BGLPT
MCID: BTG003
MIFTS: 12

Beta-Glucopyranoside Tasting (BGLPT)

Categories: Genetic diseases

Aliases & Classifications for Beta-Glucopyranoside Tasting

MalaCards integrated aliases for Beta-Glucopyranoside Tasting:

Name: Beta-Glucopyranoside Tasting 56 6
Beta-Glycopyranoside Tasting , (3) Alcohol Dependence, Susceptibility to 56
Beta-Glycopyranoside Tasting , (3) Alcohol Dependence 56
Bglpt 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant

Miscellaneous:
most populations outside of africa carry the derivative allele that confers increased sensitivity to bitter taste


HPO:

31
beta-glucopyranoside tasting:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 56 617956
MedGen 41 C4693750
SNOMED-CT via HPO 68 263681008

Summaries for Beta-Glucopyranoside Tasting

OMIM : 56 Among the 5 taste modalities recognized by humans (bitter, sweet, sour, umami, and salty), bitter taste plays an important protective role because many plant toxins have a bitter taste. The G protein-coupled receptor encoded by TAS2R16 mediates response to salicin, amygdalin, and many bitter beta-glucopyranosides. Beta-glucopyranosides are synthesized by over 2,500 plant and insect species as a protection against predators. This family also includes various toxic cyanogenic glycosides (summary by Soranzo et al., 2005). (617956)

MalaCards based summary : Beta-Glucopyranoside Tasting, is also known as beta-glycopyranoside tasting , (3) alcohol dependence, susceptibility to. An important gene associated with Beta-Glucopyranoside Tasting is TAS2R16 (Taste 2 Receptor Member 16).

Related Diseases for Beta-Glucopyranoside Tasting

Symptoms & Phenotypes for Beta-Glucopyranoside Tasting

Symptoms via clinical synopsis from OMIM:

56
Head And Neck Mouth:
increased sensitivity to bitter taste

Clinical features from OMIM:

617956

Drugs & Therapeutics for Beta-Glucopyranoside Tasting

Search Clinical Trials , NIH Clinical Center for Beta-Glucopyranoside Tasting

Genetic Tests for Beta-Glucopyranoside Tasting

Anatomical Context for Beta-Glucopyranoside Tasting

Publications for Beta-Glucopyranoside Tasting

Articles related to Beta-Glucopyranoside Tasting:

(showing 6, show less)
# Title Authors PMID Year
1
Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. 6 56
24177185 2014
2
Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16. 56 6
16051168 2005
3
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. 6
17250611 2007
4
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. 6
16385453 2006
5
Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. 6
10923994 2000
6
Genome-wide search for genes affecting the risk for alcohol dependence. 6
9603606 1998

Variations for Beta-Glucopyranoside Tasting

ClinVar genetic disease variations for Beta-Glucopyranoside Tasting:

6 (showing 1, show less) ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 TAS2R16 NM_016945.3(TAS2R16):c.516T>G (p.Asn172Lys)SNV risk factor 5333 rs846664 7:122635173-122635173 7:122995119-122995119

Expression for Beta-Glucopyranoside Tasting

Search GEO for disease gene expression data for Beta-Glucopyranoside Tasting.

Pathways for Beta-Glucopyranoside Tasting

GO Terms for Beta-Glucopyranoside Tasting

Sources for Beta-Glucopyranoside Tasting

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....