MCID: BCR002
MIFTS: 24

Bicornuate Uterus

Categories: Fetal diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Bicornuate Uterus

MalaCards integrated aliases for Bicornuate Uterus:

Name: Bicornuate Uterus 58 29 54 6

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 33 Q51.3
UMLS via Orphanet 72 C0266387
Orphanet 58 ORPHA180134

Summaries for Bicornuate Uterus

MalaCards based summary : Bicornuate Uterus is related to didelphys uterus and unicervical bicornuate uterus. An important gene associated with Bicornuate Uterus is HNF1B (HNF1 Homeobox B). Affiliated tissues include uterus, cervix and placenta.

Wikipedia : 74 A bicornuate uterus or bicornate uterus (from the Latin cornū, meaning "horn"), is a type of mullerian... more...

Related Diseases for Bicornuate Uterus

Diseases related to Bicornuate Uterus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 didelphys uterus 11.2
2 unicervical bicornuate uterus 11.2
3 bicervical bicornuate uterus and blind hemivagina 11.2
4 bicervical bicornuate uterus with patent cervix and vagina 11.2
5 renal cysts and diabetes syndrome 11.2
6 uterine anomalies 10.6
7 renal hypodysplasia/aplasia 1 10.5
8 infertility 10.4
9 ectopic pregnancy 10.4
10 endometrial cancer 10.3
11 hemometra 10.3
12 septate uterus 10.3
13 endometrial adenocarcinoma 10.2
14 uterine inversion 10.2
15 mayer-rokitansky-kuster-hauser syndrome 10.1
16 arteriovenous malformation 10.1
17 amenorrhea 10.1
18 placenta disease 10.1
19 transverse vaginal septum 10.1
20 renal dysplasia 10.1
21 cleft palate, isolated 10.0
22 type 2 diabetes mellitus 10.0
23 epicanthus 10.0
24 leiomyoma, uterine 10.0
25 polykaryocytosis inducer 10.0
26 tracheoesophageal fistula with or without esophageal atresia 10.0
27 vater/vacterl association 10.0
28 anencephaly 10.0
29 hydatidiform mole, recurrent, 1 10.0
30 adenomyosis 10.0
31 budd-chiari syndrome 10.0
32 cervical cancer 10.0
33 maturity-onset diabetes of the young 10.0
34 hyperprolactinemia 10.0
35 hepatocellular adenoma 10.0
36 pancreatic agenesis 10.0
37 scoliosis 10.0
38 omphalocele 10.0
39 bladder exstrophy 10.0
40 endometrial hyperplasia 10.0
41 esophageal atresia 10.0
42 supine hypotensive syndrome 10.0
43 pre-eclampsia 10.0
44 meningocele 10.0
45 microcephaly 10.0
46 placenta praevia 10.0
47 hydronephrosis 10.0
48 sarcoma 10.0
49 leiomyoma 10.0
50 typhoid fever 10.0

Graphical network of the top 20 diseases related to Bicornuate Uterus:



Diseases related to Bicornuate Uterus

Symptoms & Phenotypes for Bicornuate Uterus

Drugs & Therapeutics for Bicornuate Uterus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Sonographic Assessment of Myometrial Thickness as a Predictor for the Latency Interval in Women With Preterm Premature Rupture of Membranes Unknown status NCT02380560

Search NIH Clinical Center for Bicornuate Uterus

Genetic Tests for Bicornuate Uterus

Genetic tests related to Bicornuate Uterus:

# Genetic test Affiliating Genes
1 Bicornuate Uterus 29

Anatomical Context for Bicornuate Uterus

MalaCards organs/tissues related to Bicornuate Uterus:

40
Uterus, Cervix, Placenta, Ovary, Endothelial, Fetal Brain

Publications for Bicornuate Uterus

Articles related to Bicornuate Uterus:

(show top 50) (show all 479)
# Title Authors PMID Year
1
Splice site mutation in the hepatocyte nuclear factor-1 beta gene, IVS2nt + 1G > A, associated with maturity-onset diabetes of the young, renal dysplasia and bicornuate uterus. 61 54
11317673 2001
2
Abdominoperineal anoplasty with use of a rectal fistula as a substitute vagina in a cloacal malformation associated with absence of the vagina: short-term follow-up. 61
33585028 2021
3
Diagnosis and management of rudimentary horn pregnancy rupture, misinterpreted as bicornuate uterus in the 14th week of pregnancy. 61
33271628 2021
4
Persistent breech presentation in a bicornuate uterus. 61
32565237 2021
5
Adenomyotic cyst mimicking a congenital Müllerian anomaly: Diagnosis and treatment with laparoscopy. 61
33467841 2021
6
Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy. 61
33575266 2021
7
Placenta percreta after Strassman metroplasty of complete bicornuate uterus: a case report. 61
33514327 2021
8
VNOTES (Vaginal Natural Orifices Transluminal Endoscopic Surgery) myomectomy through anterior cul-de-sac approach on the bicornuate uterus. 61
32931956 2021
9
Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation. 61
33360540 2021
10
Effects of bicornuate uterus on pregnancy and obstetric outcomes of in vitro fertilization / intracytoplasmic sperm injection. 61
33421810 2020
11
Congenital diaphragmatic hernia as a prominent feature of a SPECC1L-related syndrome. 61
32954677 2020
12
Favorable pregnancy outcome for a patient with Robert's uterus, bicornuate uterus, and ipsilateral renal agenesis. 61
32542745 2020
13
Cervical length surveillance for predicting spontaneous preterm birth in women with uterine anomalies: A cohort study. 61
32438506 2020
14
Avoiding the fatal misdiagnosis of pregnancy in a noncommunicating rudimentary horn using 3D transvaginal ultrasound. 61
32255499 2020
15
Longitudinal vaginal septum: a proposed classification and surgical management. 61
32826051 2020
16
First-trimester rupture of a gravid bicornuate uterus after prior vaginal deliveries, simulating a ruptured ectopic pregnancy: a case report. 61
33133501 2020
17
A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the HNF1B gene. 61
32461507 2020
18
Twin pregnancy in a bicornuate uterus in rural Kenya: A case report for accidental discovery and successful delivery. 61
32787410 2020
19
Mosaic Trisomy 12: Prenatal Diagnosis at Amniocentesis and Molecular Genetic Analysis on Fetal Tissues. 61
32609035 2020
20
Morphology of male and female reproductive tract of the ocelot (Leopardus pardalis). 61
32714460 2020
21
Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA). 61
31931122 2020
22
Management of Mullerian Development Anomalies: 9 Years' Experience of a Tertiary Care Center. 61
32676285 2020
23
Diagnosis and treatment of müllerian malformations. 61
32127135 2020
24
Case Report: Spontaneous perforation of a bicornuate uterus with concomitant sarcoma. 61
33447379 2020
25
Inguinal herniation of left ovary, fallopian tube and rudimentary left horn of bicornuate uterus associated with type 2 Mayer-Rakitansky-Kuster-Hauser (MRKH) syndrome in a teenage girl: A case report and literature review. 61
32021881 2020
26
Laparoscopic Hysterectomy and Bilateral Salpingectomy in a Patient with Microduplication Syndrome (20p13p12.1) and a Bicornuate Uterus: An Unreported Association. 61
32904596 2020
27
Rare cases of ectopic ureter: Analysis from a single centre with review of the literature. 61
30475701 2019
28
Unintended pregnancy with IUD in situ reveals the IUD placement into one of the uterine horns in a bicornuate uterus. 61
31796441 2019
29
Müllerian Anomalies Prevalence Diagnosed by Hysteroscopy and Laparoscopy in Mexican Infertile Women: Results from a Cohort Study. 61
31627332 2019
30
Currarino syndrome in an adult woman. 61
31538082 2019
31
Treatment of locally advanced cervical cancer in a patient with a bicornuate uterus with MRI-guided intracavitary/interstitial brachytherapy. 61
31435436 2019
32
Bicornuate Uterus with Complete Cervico-Vaginal Agenesis and Skeletal Deformity: A Case Report. 61
30956497 2019
33
Frequency and types of uterine anomalies during caesarean section. 61
30372654 2019
34
Successful delivery of spontaneously conceived twins in a single horn of a bicornuate uterus: A case report. 61
30886828 2019
35
Successful Management of Complicated Uterine Displacement Caused by Unilateral Incarceration of the Bicornuate Uterus. 61
30984434 2019
36
Congenital anal atresia with rectovestibular fistula, scoliosis, unilateral renal agenesis, and finger defect (VACTERL association) in a patient with partial bicornuate uterus and distal vaginal atresia: A case report. 61
30407282 2018
37
Modified ex utero intrapartum treatment procedure in a bicornuate uterus breech presentation Pierre Robin fetus with severe micrognathia and cleft palate. 61
30455887 2018
38
Uterine didelphys with one cervix obscured by blind hemivagina: a lesson in rarity. 61
30077979 2018
39
Obstetric outcome in patients with a unicornuate uterus after laparoscopic resection of a rudimentary horn. 61
29516633 2018
40
Endometrial carcinoma in a single horn of a bicornuate uterus: A case report. 61
29779939 2018
41
Are 3D ultrasound and office hysteroscopy useful for the assessment of uterine cavity after late foetal loss? 61
29475047 2018
42
Uterine torsion and subsequent rupture in a gravid bicornuate uterus associated with an elevated alpha-fetoprotein. 61
29804076 2018
43
Successful use of balloon tamponade in the management of postpartum hemorrhage in a case of bicornuate uterus. 61
29796270 2018
44
Successful Pregnancy Outcome after Open Strassman Metroplasty for Bicornuate Uterus. 61
30018833 2018
45
Bicornuate Bicollis Uterus with Obstruction of the Lower Uterine Segment and Cervical Prolapse Complicating Pregnancy. 61
30186650 2018
46
De novo HNF1 homeobox B mutation as a cause for chronic, treatment-resistant hypomagnesaemia. 61
29576871 2018
47
Dietary management of maternal phenylketonuria with glycomacropeptide and amino acids supplements: A case report. 61
29085781 2017
48
The spectrum of imaging appearances of müllerian duct anomalies: focus on MR imaging. 61
28921452 2017
49
Bicornuate uterus is an independent risk factor for cervical os insufficiency: A retrospective population based cohort study. 61
27903074 2017
50
Scar Endometriosis with Rudimentary Horn: An Unusual and Elucidative Report of a Case Diagnosed on Histopathology and Immunohistochemistry. 61
29307985 2017

Variations for Bicornuate Uterus

Expression for Bicornuate Uterus

Search GEO for disease gene expression data for Bicornuate Uterus.

Pathways for Bicornuate Uterus

GO Terms for Bicornuate Uterus

Sources for Bicornuate Uterus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....