MCID: BCR002
MIFTS: 25

Bicornuate Uterus

Categories: Fetal diseases, Rare diseases, Reproductive diseases
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Aliases & Classifications for Bicornuate Uterus

MalaCards integrated aliases for Bicornuate Uterus:

Name: Bicornuate Uterus 58 28 53 5 75 33
Uterus Bicornis 33
Uterus Biforis 33
Bifid Uterus 33

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases
Developmental anomalies during embryogenesis


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ICD10 via Orphanet 32 Q51.3
UMLS via Orphanet 72 C0266387
Orphanet 58 ORPHA180134
ICD11 33 1965739367

Summaries for Bicornuate Uterus

MalaCards based summary: Bicornuate Uterus, also known as uterus bicornis, is related to teebi hypertelorism syndrome 1 and omphalocele-cleft palate syndrome, lethal. An important gene associated with Bicornuate Uterus is HNF1B (HNF1 Homeobox B). Affiliated tissues include uterus, cervix and placenta.

Wikipedia: 75 A bicornuate uterus or bicornate uterus (from the Latin cornū, meaning "horn"), is a type of mullerian... more...

Related Diseases for Bicornuate Uterus

Diseases related to Bicornuate Uterus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 teebi hypertelorism syndrome 1 11.3
2 omphalocele-cleft palate syndrome, lethal 11.3
3 didelphys uterus 11.3
4 unicervical bicornuate uterus 11.2
5 uterus bicornis bicollis with partial vaginal septum and unilateral hematocolpos with ipsilateral renal agenesis 11.2
6 bicervical bicornuate uterus and blind hemivagina 11.2
7 bicervical bicornuate uterus with patent cervix and vagina 11.2
8 renal cysts and diabetes syndrome 11.2
9 46,xx disorder of sex development-anorectal anomalies syndrome 11.2
10 uterine anomalies 10.6
11 renal hypodysplasia/aplasia 1 10.6
12 septate vagina 10.5
13 ectopic pregnancy 10.4
14 endometrial cancer 10.3
15 renal hypodysplasia/aplasia 3 10.3
16 hemometra 10.3
17 septate uterus 10.3
18 endometrial adenocarcinoma 10.3
19 infertility 10.3
20 amenorrhea 10.2
21 uterine inversion 10.2
22 renal dysplasia 10.2
23 basal cell nevus syndrome 10.2
24 gynatresia 10.2
25 peritonitis 10.2
26 leiomyoma, uterine 10.1
27 hymen, imperforate 10.1
28 mayer-rokitansky-kuster-hauser syndrome 10.1
29 adenomyosis 10.1
30 pregnancy loss, recurrent 1 10.1
31 pre-eclampsia 10.1
32 arteriovenous malformation 10.1
33 endometriosis 10.1
34 placental abruption 10.1
35 cervical incompetence 10.1
36 vagina, absence of 10.1
37 transverse vaginal septum 10.1
38 ovarian cancer 10.0
39 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.0
40 rhabdomyosarcoma 2 10.0
41 focal dermal hypoplasia 10.0
42 basal cell carcinoma 1 10.0
43 benign teratoma 10.0
44 adult respiratory distress syndrome 10.0
45 potter's syndrome 10.0
46 basal cell carcinoma 10.0
47 skin disease 10.0
48 vaginal discharge 10.0
49 dermoid cyst of ovary 10.0
50 pyosalpinx 10.0

Graphical network of the top 20 diseases related to Bicornuate Uterus:



Diseases related to Bicornuate Uterus

Symptoms & Phenotypes for Bicornuate Uterus

Drugs & Therapeutics for Bicornuate Uterus

Search Clinical Trials, NIH Clinical Center for Bicornuate Uterus

Genetic Tests for Bicornuate Uterus

Genetic tests related to Bicornuate Uterus:

# Genetic test Affiliating Genes
1 Bicornuate Uterus 28

Anatomical Context for Bicornuate Uterus

Organs/tissues related to Bicornuate Uterus:

MalaCards : Uterus, Cervix, Placenta, Kidney, Ovary, Small Intestine, Fetal Brain

Publications for Bicornuate Uterus

Articles related to Bicornuate Uterus:

(show top 50) (show all 699)
# Title Authors PMID Year
1
Splice site mutation in the hepatocyte nuclear factor-1 beta gene, IVS2nt + 1G > A, associated with maturity-onset diabetes of the young, renal dysplasia and bicornuate uterus. 53 62
11317673 2001
2
The association between congenital uterine anomalies and perinatal outcomes - does type of defect matters? 62
34238096 2022
3
Five-vessel umbilical cord and fetal outcome: an obstetric overview. 62
33847222 2022
4
Double Trouble: A Singleton in Each Horn of a Bicornuate Uterus. 62
36180737 2022
5
Diagnosis and Management of Mullerian Anomalies Across Differing Resource Settings: Worldwide Adaptations. 62
35489471 2022
6
Low-set umbilicus in a pregnant woman with bladder pseudoexstrophy: A case report. 62
36406178 2022
7
A case of right hypodysplastic kidney and ectopic ureter associated with bicornuate uterus in a prepubertal girl. 62
36056295 2022
8
A Case Report of a Normal Pregnancy in a Bicornuate Uterus Through In Vitro Fertilization. 62
36259042 2022
9
How do bicornuate uteri alter pregnancy, intra-partum and neonatal risks? A population based study of more than three million deliveries and more than 6000 bicornuate uteri. 62
35946504 2022
10
Torsion of unscarred gravid horn of a bicornuate uterus with abnormal foetal lie. 62
35019821 2022
11
Spontaneous Haemoperitoneum in Pregnancy with Placenta Percreta in Bicornuate Uterus with Successful Pregnancy Outcome: A case study. 62
35673281 2022
12
A "cluster" of ten uterine anomalies observed in a single center over a short period of 4 weeks: a case series. 62
35365244 2022
13
Mosaic Trisomy 12: Prenatal Diagnosis at Amniocentesis and Molecular Genetic Analysis on Fetal Tissues. 62
32609035 2022
14
Spontaneous twin pregnancy in uterus bicornis unicollis complicated with preeclampsia: A case report. 62
35278983 2022
15
A unique case of coexisting intrauterine and abdominal pregnancy which progress to term with a positive birth outcome. 62
35331173 2022
16
Short Bones, Renal Stones, and Diagnostic Moans: Hypercalcemia in a Girl Found to Have Coffin-Lowry Syndrome. 62
35638718 2022
17
Diabetes Mellitus With Renal and Müllerian Anomalies. 62
35097197 2022
18
The first case of novel variants of FSHR mutation causing primary amenorrhea in two siblings in Korea. 62
35038834 2022
19
A New Case of Herlyn-Werner-Wunderlich Syndrome: Uterine Didelphys with Unilateral Cervical Dysgenesis, Vaginal Agenesis, Cervical Distal Ureteral Remnant Fistula, Ureterocele, and Renal Agenesis in a Patient with Contralateral Multicystic Dysplastic Kidney. 62
35054250 2021
20
Does Preoperative Diagnosis Will Change the Treatment Plan of Clear Cell Carcinoma of Endometrium Masquerading as Desmoid Tumor of Anterior Abdominal Wall?: a Case Report. 62
35035162 2021
21
A case of digenic maturity onset diabetes of the young with heterozygous variants in both HNF1Α and HNF1Β genes. 62
34161864 2021
22
Evaluation of Sporadic and Familial Cases with Craniofrontonasal Syndrome: A Wide Clinical Spectrum and Identification of a Novel EFNB1 Gene Mutation. 62
34602953 2021
23
Clinical and molecular characterization of craniofrontonasal syndrome: new symptoms and novel pathogenic variants in the EFNB1 gene. 62
34174922 2021
24
Long-Term Results of an Imperforate Hymen Procedure that Leaves the Hymen Intact. 62
34149219 2021
25
Congenital Uterine Anomaly and Pelvic Organ Prolapse: A Rare Case of Pelvic Organ Prolapse in a Complete Bicornuate Uterus with Successful Pregnancy Outcomes Undiagnosed until the Time of Sacrocolpopexy. 62
33942587 2021
26
Effects of bicornuate uterus on pregnancy and obstetric outcomes of in vitro fertilization / intracytoplasmic sperm injection. 62
33421810 2021
27
Successful Delivery after Uterine Rupture with Pervious Open Strassman Metroplasty for a Bicornuate Uterus in a Twin Pregnancy. 62
33753959 2021
28
Adenomyotic cyst mimicking a congenital Müllerian anomaly: Diagnosis and treatment with laparoscopy. 62
33467841 2021
29
Diagnosis and management of rudimentary horn pregnancy rupture, misinterpreted as bicornuate uterus in the 14th week of pregnancy. 62
33271628 2021
30
Abdominoperineal anoplasty with use of a rectal fistula as a substitute vagina in a cloacal malformation associated with absence of the vagina: short-term follow-up. 62
33585028 2021
31
Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation. 62
33360540 2021
32
VNOTES (Vaginal Natural Orifices Transluminal Endoscopic Surgery) myomectomy through anterior cul-de-sac approach on the bicornuate uterus. 62
32931956 2021
33
Advanced Abdominal Pregnancy (AAP) after 20 Weeks of Gestation in Japan: A Retrospective Review. 62
34349802 2021
34
Persistent breech presentation in a bicornuate uterus. 62
32565237 2021
35
[Hydrocele of the canal of Nuck detected during infertility evaluation: an atypical case report]. 62
34285744 2021
36
Case Report: Recurrent Placental Abruption During Pregnancy in a Patient With Pseudoexstrophy. 62
33575266 2021
37
Placenta percreta after Strassman metroplasty of complete bicornuate uterus: a case report. 62
33514327 2021
38
Congenital diaphragmatic hernia as a prominent feature of a SPECC1L-related syndrome. 62
32954677 2020
39
Favorable pregnancy outcome for a patient with Robert's uterus, bicornuate uterus, and ipsilateral renal agenesis. 62
32542745 2020
40
Cervical length surveillance for predicting spontaneous preterm birth in women with uterine anomalies: A cohort study. 62
32438506 2020
41
Avoiding the fatal misdiagnosis of pregnancy in a noncommunicating rudimentary horn using 3D transvaginal ultrasound. 62
32255499 2020
42
Longitudinal vaginal septum: a proposed classification and surgical management. 62
32826051 2020
43
First-trimester rupture of a gravid bicornuate uterus after prior vaginal deliveries, simulating a ruptured ectopic pregnancy: a case report. 62
33133501 2020
44
A case of MODY5-like manifestations without mutations or deletions in coding and minimal promoter regions of the HNF1B gene. 62
32461507 2020
45
Twin pregnancy in a bicornuate uterus in rural Kenya: A case report for accidental discovery and successful delivery. 62
32787410 2020
46
Morphology of male and female reproductive tract of the ocelot (Leopardus pardalis). 62
32714460 2020
47
Two successful spontaneous pregnancies, single and twin, in uterus bicornis unicollis after deep infiltration endometriosis surgery. 62
32159316 2020
48
Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA). 62
31931122 2020
49
Evolution of placentation in cattle and antelopes. 62
33936288 2020
50
Management of Mullerian Development Anomalies: 9 Years' Experience of a Tertiary Care Center. 62
32676285 2020

Variations for Bicornuate Uterus

Expression for Bicornuate Uterus

Search GEO for disease gene expression data for Bicornuate Uterus.

Pathways for Bicornuate Uterus

GO Terms for Bicornuate Uterus

Sources for Bicornuate Uterus

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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