MCID: BDR001
MIFTS: 19

Bidirectional Tachycardia

Categories: Rare diseases

Aliases & Classifications for Bidirectional Tachycardia

MalaCards integrated aliases for Bidirectional Tachycardia:

Name: Bidirectional Tachycardia 53 72
Bidirectional Ventricular Tachycardia 53

Classifications:



External Ids:

UMLS 72 C2930902

Summaries for Bidirectional Tachycardia

MalaCards based summary : Bidirectional Tachycardia, also known as bidirectional ventricular tachycardia, is related to catecholaminergic polymorphic ventricular tachycardia and ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy. The drugs Propranolol and Metoprolol have been mentioned in the context of this disorder. Affiliated tissues include heart and testes.

Related Diseases for Bidirectional Tachycardia

Diseases related to Bidirectional Tachycardia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 catecholaminergic polymorphic ventricular tachycardia 11.7
2 ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy 11.6
3 ventricular tachycardia, catecholaminergic polymorphic, 2 11.6
4 ventricular tachycardia, catecholaminergic polymorphic, 4 11.6
5 ventricular tachycardia, familial 11.5
6 ventricular tachycardia, catecholaminergic polymorphic, 3 11.5
7 ventricular tachycardia, catecholaminergic polymorphic, 5, with or without muscle weakness 11.5
8 myocarditis 10.5
9 andersen cardiodysrhythmic periodic paralysis 10.4
10 syncope 10.4
11 cardiac conduction defect 10.3
12 atrial standstill 1 10.3
13 myocardial infarction 10.3
14 pheochromocytoma 10.2
15 adrenal gland pheochromocytoma 10.2
16 sick sinus syndrome 10.2
17 long qt syndrome 10.2
18 hypokalemia 10.2
19 acute myocardial infarction 10.2
20 ventricular fibrillation, paroxysmal familial, 1 10.1
21 progressive familial heart block, type ia 10.0
22 cardiac arrhythmia 10.0
23 sarcoidosis 1 10.0
24 pulmonary disease, chronic obstructive 10.0
25 arrhythmogenic right ventricular cardiomyopathy 10.0
26 atrioventricular block 10.0
27 atrial fibrillation 10.0
28 familial periodic paralysis 10.0
29 dilated cardiomyopathy 10.0
30 cardiac sarcoidosis 10.0
31 pulmonary sarcoidosis 10.0
32 rhabdomyosarcoma 10.0
33 acute myocarditis 10.0
34 coronary stenosis 10.0
35 47,xyy 10.0
36 hypertrophic cardiomyopathy 10.0
37 familial periodic paralyses 10.0
38 headache 10.0
39 familial long qt syndrome 10.0
40 hypokalemic periodic paralysis, type 1 9.9
41 progressive familial heart block, type ib 9.9
42 orthostatic intolerance 9.9
43 cardiac arrest 9.9
44 left bundle branch hemiblock 9.9
45 right bundle branch block 9.9
46 rheumatic disease 9.9
47 enthesopathy 9.9
48 aortic aneurysm 9.9
49 pulmonary embolism 9.9
50 aneurysm 9.9

Graphical network of the top 20 diseases related to Bidirectional Tachycardia:



Diseases related to Bidirectional Tachycardia

Symptoms & Phenotypes for Bidirectional Tachycardia

Drugs & Therapeutics for Bidirectional Tachycardia

Drugs for Bidirectional Tachycardia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propranolol Approved, Investigational 525-66-6 4946
2
Metoprolol Approved, Investigational 37350-58-6, 51384-51-1 4171
3
Nadolol Approved 42200-33-9 39147
4
Atenolol Approved 29122-68-7 2249
5 Sodium Channel Blockers
6 Diuretics, Potassium Sparing
7 Adrenergic beta-Antagonists
8 Adrenergic Antagonists
9 Neurotransmitter Agents
10 Adrenergic Agents
11 Anti-Arrhythmia Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Prospective Randomized Crossover Trial of Oral Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia Completed NCT01117454 Flecainide Acetate;Placebo;Beta blocker

Search NIH Clinical Center for Bidirectional Tachycardia

Genetic Tests for Bidirectional Tachycardia

Anatomical Context for Bidirectional Tachycardia

MalaCards organs/tissues related to Bidirectional Tachycardia:

41
Heart, Testes

Publications for Bidirectional Tachycardia

Articles related to Bidirectional Tachycardia:

(show top 50) (show all 195)
# Title Authors PMID Year
1
Polymorphic Wide QRS Complex Tachycardia: Differential Diagnosis. 38
31084854 2019
2
Bidirectional ventricular tachycardia in ACTH-producing pheochromocytoma. 38
30897623 2019
3
Catecholaminergic Polymorphic Ventricular Tachycardia: The Cardiac Arrest Where Epinephrine Is Contraindicated. 38
30640888 2019
4
Can flecainide totally eliminate bidirectional ventricular tachycardia in pediatric patients with Andersen-Tawil syndrome? 38
30516532 2018
5
Bidirectional ventricular tachycardia due to hypokalaemia. 38
30567276 2018
6
Catecholaminergic polymorphic ventricular tachycardia managed as orthostatic dysregulation and epilepsy in 11- and 15-year-old sisters. 38
30157307 2018
7
Different responses to exercise between Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia. 38
29309601 2018
8
Asymptomatic ventricular tachycardia: diagnostic pitfalls of Andersen-Tawil syndrome-a case report. 38
31020160 2018
9
A delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia with a mutant of RYR2 at c.7580T>G for 6 years in a 9-year-old child. 38
29668588 2018
10
Accelerated idioventricular rhythm degenerating into bidirectional ventricular tachycardia following acute myocardial infarction. 38
29429799 2018
11
Left Ventricular Aneurysm Presenting as Bidirectional Ventricular Tachycardia. 38
30275798 2018
12
Catecholaminergic Polymorphic Ventricular Tachycardia - Looking to the Future. 38
29610596 2017
13
Bidirectional ventricular tachycardia in ischemic cardiomyopathy during ablation. 38
29387544 2017
14
AV nodal reentrant tachycardia with a 2:1 right bundle branch block missed as bidirectional ventricular tachycardia in the first superficial evaluation. 38
28125405 2017
15
Bidirectional ventricular tachycardia in cardiac sarcoidosis. 38
28217233 2017
16
Are Olympic athletes free from cardiovascular diseases? Systematic investigation in 2352 participants from Athens 2004 to Sochi 2014. 38
28039126 2017
17
Bidirectional Ventricular Tachycardia Due to a Mixture of Focal Fascicular Firing and Reentry. 38
27837895 2016
18
Catecholaminergic polymorphic ventricular tachycardia associated with sinus node dysfunction and junctional rhythm: Case report and literature review. 38
27539163 2016
19
Current topics in catecholaminergic polymorphic ventricular tachycardia. 38
27761157 2016
20
Patient Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Development and Screening In Catecholaminergic Polymorphic Ventricular Tachycardia. 38
27909533 2016
21
An Unusual Etiology for Bidirectional Ventricular Tachycardia. 38
26604120 2016
22
Bidirectional ventricular tachycardia of unusual etiology. 38
27479206 2015
23
Catecholaminergic polymorphic ventricular tachycardia: a rare cause of recurrent syncope. 38
26512332 2015
24
Herb-induced cardiotoxicity from accidental aconitine overdose. 38
26243980 2015
25
Electrocardiogram in Andersen-Tawil syndrome. New electrocardiographic criteria for diagnosis of type-1 Andersen-Tawil syndrome. 38
24827800 2014
26
Bidirectional ventricular tachycardia with myocardial infarction: a case report with insight on mechanism and treatment. 38
25173208 2014
27
Bidirectional ventricular tachycardia associated with digoxin toxicity and with normal digoxin levels. 38
24685893 2014
28
Doxapram hydrochloride aggravates adrenaline-induced arrhythmias accompanied by bidirectional ventricular tachycardia. 38
24527224 2014
29
Bidirectional tachycardia after an acute intravenous administration of digitalis for a suicidal gesture. 38
25221680 2014
30
Bidirectional ventricular tachycardia? 38
24192425 2014
31
Outcomes of defibrillator therapy in catecholaminergic polymorphic ventricular tachycardia. 38
24120999 2014
32
Atypical bidirectional ventricular tachycardia. 38
24773999 2013
33
Novel mutation in the KCNJ2 gene is associated with a malignant arrhythmic phenotype of Andersen-Tawil syndrome. 38
24047492 2013
34
Catecholaminergic polymorphic ventricular tachycardia detected by an implantable loop recorder in a child. 38
23917010 2013
35
Bidirectional ventricular tachycardia of unknown etiology. 38
23673175 2013
36
Pheochromocytoma presenting with bidirectional ventricular tachycardia. 38
23315606 2013
37
Various morphologies of bidirectional ventricular tachycardia caused by aconite "Torikabuto" poisoning. 38
30533117 2013
38
Conduction slowing contributes to spontaneous ventricular arrhythmias in intrinsically active murine RyR2-P2328S hearts. 38
23131176 2013
39
Bidirectional ventricular tachycardia secondary to subacute myocarditis. 38
22819444 2013
40
Bidirectional ventricular tachycardia in a patient with acute myocardial infarction and aortic stenosis. 38
22658352 2013
41
Genetic background of catecholaminergic polymorphic ventricular tachycardia in Japan. 38
23595086 2013
42
Just sinus bradycardia or something more serious? 38
23476865 2013
43
[Andersen-Tawil syndrome. Efficacy of class IC drugs]. 38
23548357 2013
44
Bidirectional ventricular tachycardia in a patient with exacerbation of chronic obstructive pulmonary disease. 38
22552834 2012
45
Bidirectional ventricular tachycardia due to coronary allograft vasculopathy a unique presentation. 38
23094889 2012
46
Andersen-Tawil syndrome associated with aborted sudden cardiac death: atrial pacing was effective for ventricular arrhythmias. 38
22739561 2012
47
Treatment of asymptomatic catecholaminergic polymorphic ventricular tachycardia. 38
22642633 2012
48
Alternans of diastolic intracellular calcium elevation as the mechanism of bidirectional ventricular tachycardia in a rabbit model of Andersen-Tawil syndrome. 38
21167318 2012
49
Bidirectional ventricular tachycardia: a hallmark of catecholaminergic polymorphic ventricular tachycardia. 38
22557844 2012
50
Catecholaminergic polymorphic ventricular tachycardia in a patient with recurrent exertional syncope. 38
22396703 2012

Variations for Bidirectional Tachycardia

Expression for Bidirectional Tachycardia

Search GEO for disease gene expression data for Bidirectional Tachycardia.

Pathways for Bidirectional Tachycardia

GO Terms for Bidirectional Tachycardia

Sources for Bidirectional Tachycardia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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