MCID: BLD035
MIFTS: 30

Bile Duct Cystadenoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Bile Duct Cystadenoma

MalaCards integrated aliases for Bile Duct Cystadenoma:

Name: Bile Duct Cystadenoma 12 15 71
Cystadenoma of the Bile Duct 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5384
NCIt 49 C4129
SNOMED-CT 67 83025009
UMLS 71 C0334285

Summaries for Bile Duct Cystadenoma

Disease Ontology : 12 A biliary tract benign neoplasm that is located in the bile duct and derives from epithelial cells.

MalaCards based summary : Bile Duct Cystadenoma, also known as cystadenoma of the bile duct, is related to intrahepatic bile duct cystadenoma and extrahepatic bile duct cystadenoma, and has symptoms including abdominal pain and icterus. An important gene associated with Bile Duct Cystadenoma is PER3 (Period Circadian Regulator 3), and among its related pathways/superpathways are Circadian rythm related genes and Integrated Breast Cancer Pathway. Affiliated tissues include bile duct, breast and liver, and related phenotypes are homeostasis/metabolism and nervous system

Related Diseases for Bile Duct Cystadenoma

Graphical network of the top 20 diseases related to Bile Duct Cystadenoma:



Diseases related to Bile Duct Cystadenoma

Symptoms & Phenotypes for Bile Duct Cystadenoma

UMLS symptoms related to Bile Duct Cystadenoma:


abdominal pain, icterus

MGI Mouse Phenotypes related to Bile Duct Cystadenoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.5 ARNTL ATM CD200 CHEK2 CLOCK ESR1
2 nervous system MP:0003631 9.17 ARNTL ATM CD200 CHEK2 CLOCK ESR1

Drugs & Therapeutics for Bile Duct Cystadenoma

Search Clinical Trials , NIH Clinical Center for Bile Duct Cystadenoma

Genetic Tests for Bile Duct Cystadenoma

Anatomical Context for Bile Duct Cystadenoma

The Foundational Model of Anatomy Ontology organs/tissues related to Bile Duct Cystadenoma:

19
Bile Duct

MalaCards organs/tissues related to Bile Duct Cystadenoma:

40
Breast, Liver, Heart, Ovary, Myeloid, T Cells, Tongue

Publications for Bile Duct Cystadenoma

Articles related to Bile Duct Cystadenoma:

# Title Authors PMID Year
1
Definitive diagnosis of a duplicate gallbladder can only be made intraoperatively: report of a case. 61
26185884 2014
2
Adult mesenchymal hamartoma of the liver mimicking bile duct cystadenoma. 61
7951866 1994
3
Biliary obstruction due to intraductal tumor. 61
2548467 1989
4
[Surgically removed bile duct cystadenoma]. 61
5212262 1968
5
Bile duct cystadenoma of the liver. 61
6027619 1967
6
[Benign tumor of biliary tract papillary cystadenoma of the bile duct]. 61
13344312 1956

Variations for Bile Duct Cystadenoma

Expression for Bile Duct Cystadenoma

Search GEO for disease gene expression data for Bile Duct Cystadenoma.

Pathways for Bile Duct Cystadenoma

GO Terms for Bile Duct Cystadenoma

Cellular components related to Bile Duct Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromosome, telomeric region GO:0000781 8.96 CHEK2 ATM
2 chromatoid body GO:0033391 8.62 CLOCK ARNTL

Biological processes related to Bile Duct Cystadenoma according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.81 ESR1 CLOCK CHEK2 ARNTL
2 rhythmic process GO:0048511 9.65 PER3 CLOCK ARNTL
3 regulation of insulin secretion GO:0050796 9.56 CLOCK ARNTL
4 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9.55 CHEK2 ATM
5 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.54 CHEK2 ATM
6 circadian rhythm GO:0007623 9.54 PER3 CLOCK ARNTL
7 cellular response to gamma radiation GO:0071480 9.52 CHEK2 ATM
8 regulation of protein catabolic process GO:0042176 9.49 CHEK2 ARNTL
9 replicative senescence GO:0090399 9.46 CHEK2 ATM
10 response to redox state GO:0051775 9.43 CLOCK ARNTL
11 DNA damage induced protein phosphorylation GO:0006975 9.4 CHEK2 ATM
12 circadian regulation of gene expression GO:0032922 9.33 PER3 CLOCK ARNTL
13 negative regulation of glucocorticoid receptor signaling pathway GO:2000323 9.32 CLOCK ARNTL
14 regulation of hair cycle GO:0042634 9.26 CLOCK ARNTL
15 regulation of type B pancreatic cell development GO:2000074 8.96 CLOCK ARNTL
16 DNA damage checkpoint GO:0000077 8.8 CLOCK CHEK2 ATM

Molecular functions related to Bile Duct Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 E-box binding GO:0070888 8.96 CLOCK ARNTL
2 protein dimerization activity GO:0046983 8.8 CLOCK ATM ARNTL

Sources for Bile Duct Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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