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MCID: BLD002
MIFTS: 26

Bile Duct Mucinous Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes
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Aliases & Classifications for Bile Duct Mucinous Adenocarcinoma

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MalaCards integrated aliases for Bile Duct Mucinous Adenocarcinoma:

Name: Bile Duct Mucinous Adenocarcinoma 12 15
Extrahepatic Bile Duct Mucinous Adenocarcinoma 71
Mucinous Carcinoma of the Bile Duct 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases Liver diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:3698
NCIt 49 C5846
UMLS 71 C0861856
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Summaries for Bile Duct Mucinous Adenocarcinoma

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MalaCards based summary : Bile Duct Mucinous Adenocarcinoma, also known as extrahepatic bile duct mucinous adenocarcinoma, is related to biliary papillomatosis and urinary bladder villous adenoma, and has symptoms including vomiting, abdominal pain and pruritus. An important gene associated with Bile Duct Mucinous Adenocarcinoma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are CLEC7A (Dectin-1) signaling and O-linked glycosylation. Affiliated tissues include lung, breast and ovary.

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Related Diseases for Bile Duct Mucinous Adenocarcinoma

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Diseases related to Bile Duct Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 294)
# Related Disease Score Top Affiliating Genes
1 biliary papillomatosis 10.4 MUC5AC MUC1
2 urinary bladder villous adenoma 10.3 MUC5AC MUC1
3 villous adenoma 10.3 MUC5AC MUC1
4 mucinous intrahepatic cholangiocarcinoma 10.3 MUC5AC MUC1
5 bile duct cystadenocarcinoma 10.3 MUC5AC MUC1
6 solid adenocarcinoma with mucin production 10.3 MUC5AC MUC1
7 pancreatic intraductal papillary-mucinous neoplasm 10.3 MUC5AC MUC1
8 pancreatic mucinous cystadenoma 10.3 MUC5AC MUC1
9 colorectal cancer, hereditary nonpolyposis, type 8 10.3 MUC5AC MUC1
10 complete androgen insensitivity syndrome 10.3 MUC5AC MUC1
11 androgen insensitivity syndrome 10.3 MUC5AC MUC1
12 filamentary keratitis 10.3 MUC4 MUC1
13 cap polyposis 10.3 MUC5AC MUC4
14 mucinous tubular and spindle renal cell carcinoma 10.3 MUC4 MUC1
15 meconium ileus 10.3 MUC5AC MUC1
16 paget disease, extramammary 10.3 MUC5AC MUC1
17 adenomyoma 10.3 MUC4 MUC1
18 colloid carcinoma of the pancreas 10.3 MUC5B MUC1
19 vulvar eccrine porocarcinoma 10.2 SYP MUC1
20 senile ectropion 10.2 MUC5AC MUC4
21 krukenberg carcinoma 10.2 SYP MUC1
22 cerebral primitive neuroectodermal tumor 10.2 SYP MUC1
23 duodenum cancer 10.2 MUC5AC MUC1
24 anaplastic ependymoma 10.2 SYP MUC1
25 chordoid meningioma 10.2 SYP MUC1
26 ovarian small cell carcinoma 10.2 SYP MUC1
27 sarcomatoid mesothelioma 10.2 MUC4 MUC1
28 ampulla of vater adenocarcinoma 10.2 MUC5AC MUC1
29 lung mucoepidermoid carcinoma 10.2 MUC5B MUC5AC
30 clear cell meningioma 10.2 SYP MUC1
31 myxopapillary ependymoma 10.2 SYP MUC1
32 pancreatic foamy gland adenocarcinoma 10.2 TP53 MUC1
33 blepharitis 10.2 MUC5AC MUC4
34 pancreatoblastoma 10.2 SYP MUC1
35 perivascular epithelioid cell tumor 10.2 SYP MUC1
36 myxoid chondrosarcoma 10.2 SYP MUC1
37 ovarian serous cystadenofibroma 10.2 TP53 MUC1
38 adenofibroma 10.1 TP53 MUC1
39 endosalpingiosis 10.1 TP53 MUC1
40 parotid disease 10.1 TP53 MUC1
41 lacrimal apparatus disease 10.1 MUC5AC MUC4
42 spiradenoma 10.1 TP53 MUC1
43 nonspecific interstitial pneumonia 10.1 MUC5B MUC1
44 microglandular adenosis 10.1 TP53 MUC1
45 status asthmaticus 10.1 MUC5B MUC5AC
46 sarcomatoid renal cell carcinoma 10.1 TP53 MUC1
47 epithelial-myoepithelial carcinoma 10.1 TP53 MUC1
48 myoepithelial carcinoma 10.1 TP53 MUC1
49 papillary carcinoma 10.1
50 pituitary carcinoma 10.1 TP53 MUC1

Graphical network of the top 20 diseases related to Bile Duct Mucinous Adenocarcinoma:



Diseases related to Bile Duct Mucinous Adenocarcinoma
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Symptoms & Phenotypes for Bile Duct Mucinous Adenocarcinoma

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UMLS symptoms related to Bile Duct Mucinous Adenocarcinoma:


vomiting, abdominal pain, pruritus, nausea, icterus, malaise
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Drugs & Therapeutics for Bile Duct Mucinous Adenocarcinoma

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Search Clinical Trials , NIH Clinical Center for Bile Duct Mucinous Adenocarcinoma

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Genetic Tests for Bile Duct Mucinous Adenocarcinoma

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Anatomical Context for Bile Duct Mucinous Adenocarcinoma

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MalaCards organs/tissues related to Bile Duct Mucinous Adenocarcinoma:

40
Lung, Breast, Ovary, Appendix, Pineal, Small Intestine, Pancreas
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Publications for Bile Duct Mucinous Adenocarcinoma

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Articles related to Bile Duct Mucinous Adenocarcinoma:

# Title Authors PMID Year
1
A huge intraductal papillary mucinous carcinoma of the bile duct treated by right trisectionectomy with caudate lobectomy. 61
19961613 2009
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Variations for Bile Duct Mucinous Adenocarcinoma

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Expression for Bile Duct Mucinous Adenocarcinoma

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Search GEO for disease gene expression data for Bile Duct Mucinous Adenocarcinoma.
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Pathways for Bile Duct Mucinous Adenocarcinoma

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Pathways related to Bile Duct Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
CLEC7A (Dectin-1) signaling 65
Show member pathways
 11.97 MUC5B MUC5AC MUC4 MUC1
2
O-linked glycosylation 65
Show member pathways
 11.72 MUC5B MUC5AC MUC4 MUC1
3
Diseases of glycosylation 65
Show member pathways
 11.42 MUC5B MUC5AC MUC4 MUC1
4
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) 65
Show member pathways
 10.96 MUC5B MUC5AC MUC4 MUC1
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GO Terms for Bile Duct Mucinous Adenocarcinoma

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Cellular components related to Bile Duct Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.55 MUC5B MUC5AC MUC4 MUC1 ENO2
2 extracellular space GO:0005615 9.35 MUC5B MUC5AC MUC4 MUC1 ENO2
3 Golgi lumen GO:0005796 8.92 MUC5B MUC5AC MUC4 MUC1

Biological processes related to Bile Duct Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9.32 TP53 MUC1
2 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.26 TP53 MUC1
3 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC5B MUC5AC MUC4 MUC1
4 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.16 TP53 MUC1
5 O-glycan processing GO:0016266 8.92 MUC5B MUC5AC MUC4 MUC1

Molecular functions related to Bile Duct Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 TP53 SYP
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Sources for Bile Duct Mucinous Adenocarcinoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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