Biliary Cirrhosis, Primary, 2 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Name: Biliary Cirrhosis, Primary, 2 ⁵⁶ ¹³ ⁷¹

Pbc2 ⁵⁶

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Gastrointestinal diseases Liver diseases Endocrine diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁶ 613007

OMIM Phenotypic Series ⁵⁶ PS109720

MedGen ⁴¹ C2751696

UMLS ⁷¹ C2751696

Sources

Summaries for Biliary Cirrhosis, Primary, 2

OMIM : ⁵⁶ Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (613007)

MalaCards based summary : Biliary Cirrhosis, Primary, 2, also known as pbc2, is related to primary biliary cirrhosis and biliary cirrhosis, primary, 1. An important gene associated with Biliary Cirrhosis, Primary, 2 is PBC2 (Biliary Cirrhosis, Primary, 2). Affiliated tissues include liver.

Sources

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1	Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3	Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score
1	primary biliary cirrhosis	11.6
2	biliary cirrhosis, primary, 1	10.2
3	cholestasis	10.2

Sources

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

613007

Sources

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Search Clinical Trials , NIH Clinical Center for Biliary Cirrhosis, Primary, 2

Sources

Genetic Tests for Biliary Cirrhosis, Primary, 2

Sources

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

⁴⁰

Liver

Sources

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

(show all 19)

#	Title	Authors	PMID	Year
1	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. ⁵⁶	Hirschfield GM...Siminovitch KA	19458352	2009
2	Primary biliary cirrhosis. ⁵⁶	Kaplan MM	8900092	1996
3	Changing Perception but Unaltered Reality: How Effective Is C1-C2 Fixation for Chiari Malformations without Instability? ⁶¹	Salunke P...Panchal C	31899405	2019
4	LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain. ⁶¹	Kong M...Ryu S	30552194	2019
5	Odor mitigation and bacterial community dynamics in on-site biocovers at a sanitary landfill in South Korea. ⁶¹	Yun J...Cho KS	29957505	2018
6	Chiari-related scoliosis: a single-center experience with long-term radiographic follow-up and relationship to deformity correction. ⁶¹	Ravindra VM...Brockmeyer DL	29171800	2018
7	A Complementary Metal Oxide Semiconductor Process-Compatible Ferroelectric Tunnel Junction. ⁶¹	Ambriz-Vargas F...Ruediger A	28368099	2017
8	Energy Landscape of Zirconia Phase Transitions. ⁶¹	Guan SH...Liu ZP	26075311	2015
9	Effective induction of pblac1 laccase by copper ion in Polyporus brumalis ibrc05015. ⁶¹	Nakade K...Sakamoto Y	23332833	2013
10	Ferroelectricity in Simple Binary ZrO2 and HfO2. ⁶¹	Muller J...Mikolajick T	22812909	2012
11	Ventral compression in adult patients with Chiari 1 malformation sans basilar invagination: cause and management. ⁶¹	Salunke P...Gupta SK	22075730	2012
12	Proton dynamics in strong (short) intramolecular H-bond. DFT study of the KH maleate crystal. ⁶¹	Vener MV...Tsirelson VG	19053812	2008
13	Structure of anhydrous alkali-metal formates. ⁶¹	Wilson MP...Rodger PM	16711684	2006
14	Temperature-resolved study of three [M(M'O4)4(TBPO)4] complexes (MM' = URe, ThRe, ThTc). ⁶¹	Helliwell M...Sutton AD	16434794	2006
15	Terephthalate salts: salts of monopositive cations ⁶¹	Kaduk JA	10877356	2000
16	Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. ⁶¹	Fu H...Vierstra RD	9611183	1998
17	Molecular structures of CPF-dipeptides, inhibitors for the binding of CD4 with gp120. ⁶¹	Venkatramani L...Van der Helm D	7928082	1994
18	Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. PBC1 and PBC2 trial groups. ⁶¹	Christensen E...Williams R	8253362	1993
19	Evidence that rabbit cytochrome P-450 K is encoded by the plasmid pP-450 PBc2. ⁶¹	Finlayson MJ...Johnson EF	3801023	1986

Sources

Genes for Biliary Cirrhosis, Primary, 2

Genes related to Biliary Cirrhosis, Primary, 2 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	PBC2	Biliary Cirrhosis, Primary, 2	Genetic Locus	58.64	Susceptibility factor ⁵⁶ GeneCards inferred via : Gene name (show sections)

Sources

Variations for Biliary Cirrhosis, Primary, 2

Sources

Expression for Biliary Cirrhosis, Primary, 2

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 2.

Sources

Pathways for Biliary Cirrhosis, Primary, 2

Sources

GO Terms for Biliary Cirrhosis, Primary, 2

Sources

Sources for Biliary Cirrhosis, Primary, 2

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Biliary Cirrhosis, Primary, 2 (PBC2)

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Classifications:

External Ids:

Summaries for Biliary Cirrhosis, Primary, 2

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Genetic Tests for Biliary Cirrhosis, Primary, 2

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

Genes for Biliary Cirrhosis, Primary, 2

Genes related to Biliary Cirrhosis, Primary, 2 (1 elite genes):

Variations for Biliary Cirrhosis, Primary, 2

Expression for Biliary Cirrhosis, Primary, 2

Pathways for Biliary Cirrhosis, Primary, 2

GO Terms for Biliary Cirrhosis, Primary, 2

Sources for Biliary Cirrhosis, Primary, 2