PBC2
MCID: BLR016
MIFTS: 17

Biliary Cirrhosis, Primary, 2 (PBC2)

Categories: Gastrointestinal diseases, Genetic diseases, Immune diseases, Liver diseases, Rare diseases

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Name: Biliary Cirrhosis, Primary, 2 56 13 71
Pbc2 56

Classifications:



External Ids:

OMIM 56 613007
OMIM Phenotypic Series 56 PS109720
MedGen 41 C2751696
UMLS 71 C2751696

Summaries for Biliary Cirrhosis, Primary, 2

OMIM : 56 Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (613007)

MalaCards based summary : Biliary Cirrhosis, Primary, 2, also known as pbc2, is related to primary biliary cirrhosis and biliary cirrhosis, primary, 1. An important gene associated with Biliary Cirrhosis, Primary, 2 is PBC2 (Biliary Cirrhosis, Primary, 2). Affiliated tissues include liver and breast.

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1 Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3 Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 primary biliary cirrhosis 11.6
2 biliary cirrhosis, primary, 1 10.2
3 cholestasis 10.2

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

613007

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Search Clinical Trials , NIH Clinical Center for Biliary Cirrhosis, Primary, 2

Genetic Tests for Biliary Cirrhosis, Primary, 2

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

40
Liver, Breast

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

(show all 21)
# Title Authors PMID Year
1
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. 56
19458352 2009
2
Primary biliary cirrhosis. 56
8900092 1996
3
Changing Perception but Unaltered Reality: How Effective Is C1-C2 Fixation for Chiari Malformations without Instability? 61
31899405 2020
4
Complex Chiari Malformation Presenting with Bulbar Symptoms in an Adult: Single-stage Posterior Fusion and Foramen Magnum Decompression: A Rare Case Report. 61
32181187 2020
5
Plasma membrane expression of G protein-coupled estrogen receptor (GPER)/G protein-coupled receptor 30 (GPR30) is associated with worse outcome in metachronous contralateral breast cancer. 61
32302351 2020
6
LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain. 61
30552194 2019
7
Odor mitigation and bacterial community dynamics in on-site biocovers at a sanitary landfill in South Korea. 61
29957505 2018
8
Chiari-related scoliosis: a single-center experience with long-term radiographic follow-up and relationship to deformity correction. 61
29171800 2018
9
A Complementary Metal Oxide Semiconductor Process-Compatible Ferroelectric Tunnel Junction. 61
28368099 2017
10
Energy Landscape of Zirconia Phase Transitions. 61
26075311 2015
11
Effective induction of pblac1 laccase by copper ion in Polyporus brumalis ibrc05015. 61
23332833 2013
12
Ferroelectricity in Simple Binary ZrO2 and HfO2. 61
22812909 2012
13
Ventral compression in adult patients with Chiari 1 malformation sans basilar invagination: cause and management. 61
22075730 2012
14
Proton dynamics in strong (short) intramolecular H-bond. DFT study of the KH maleate crystal. 61
19053812 2008
15
Structure of anhydrous alkali-metal formates. 61
16711684 2006
16
Temperature-resolved study of three [M(M'O4)4(TBPO)4] complexes (MM' = URe, ThRe, ThTc). 61
16434794 2006
17
Terephthalate salts: salts of monopositive cations 61
10877356 2000
18
Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. 61
9611183 1998
19
Molecular structures of CPF-dipeptides, inhibitors for the binding of CD4 with gp120. 61
7928082 1994
20
Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. PBC1 and PBC2 trial groups. 61
8253362 1993
21
Evidence that rabbit cytochrome P-450 K is encoded by the plasmid pP-450 PBc2. 61
3801023 1986

Variations for Biliary Cirrhosis, Primary, 2

Expression for Biliary Cirrhosis, Primary, 2

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 2.

Pathways for Biliary Cirrhosis, Primary, 2

GO Terms for Biliary Cirrhosis, Primary, 2

Sources for Biliary Cirrhosis, Primary, 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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