Biliary Cirrhosis, Primary, 2 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Name: Biliary Cirrhosis, Primary, 2 ⁵⁷ ¹³ ⁷²

Pbc2 ⁵⁷

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases Endocrine diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁷ 613007 PS109720

MedGen ⁴² C2751696

UMLS ⁷² C2751696

Sources

Summaries for Biliary Cirrhosis, Primary, 2

OMIM : ⁵⁷ Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (613007)

MalaCards based summary : Biliary Cirrhosis, Primary, 2, also known as pbc2, is related to primary biliary cirrhosis and biliary cirrhosis, primary, 1. An important gene associated with Biliary Cirrhosis, Primary, 2 is PBC2 (Biliary Cirrhosis, Primary, 2). Affiliated tissues include liver.

Sources

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1	Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3	Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score
1	primary biliary cirrhosis	11.6
2	biliary cirrhosis, primary, 1	10.2
3	cholestasis	10.2
4	liver cirrhosis	10.2
5	primary biliary cholangitis	10.2

Graphical network of the top 20 diseases related to Biliary Cirrhosis, Primary, 2:

Sources

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

613007

Sources

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Search Clinical Trials , NIH Clinical Center for Biliary Cirrhosis, Primary, 2

Sources

Genetic Tests for Biliary Cirrhosis, Primary, 2

Sources

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

⁴¹

Liver

Sources

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

(show all 18)

#	Title	Authors	PMID	Year
1	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. ⁸	Hirschfield GM...Siminovitch KA	19458352	2009
2	Primary biliary cirrhosis. ⁸	Kaplan MM	8900092	1996
3	LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain. ³⁸	Kong M...Ryu S	30552194	2019
4	Odor mitigation and bacterial community dynamics in on-site biocovers at a sanitary landfill in South Korea. ³⁸	Yun J...Cho KS	29957505	2018
5	Chiari-related scoliosis: a single-center experience with long-term radiographic follow-up and relationship to deformity correction. ³⁸	Ravindra VM...Brockmeyer DL	29171800	2018
6	A Complementary Metal Oxide Semiconductor Process-Compatible Ferroelectric Tunnel Junction. ³⁸	Ambriz-Vargas F...Ruediger A	28368099	2017
7	Energy Landscape of Zirconia Phase Transitions. ³⁸	Guan SH...Liu ZP	26075311	2015
8	Effective induction of pblac1 laccase by copper ion in Polyporus brumalis ibrc05015. ³⁸	Nakade K...Sakamoto Y	23332833	2013
9	Ferroelectricity in Simple Binary ZrO2 and HfO2. ³⁸	Muller J...Mikolajick T	22812909	2012
10	Ventral compression in adult patients with Chiari 1 malformation sans basilar invagination: cause and management. ³⁸	Salunke P...Gupta SK	22075730	2012
11	Proton dynamics in strong (short) intramolecular H-bond. DFT study of the KH maleate crystal. ³⁸	Vener MV...Tsirelson VG	19053812	2008
12	Structure of anhydrous alkali-metal formates. ³⁸	Wilson MP...Rodger PM	16711684	2006
13	Temperature-resolved study of three [M(M'O4)4(TBPO)4] complexes (MM' = URe, ThRe, ThTc). ³⁸	Helliwell M...Sutton AD	16434794	2006
14	Terephthalate salts: salts of monopositive cations ³⁸	Kaduk JA	10877356	2000
15	Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. ³⁸	Fu H...Vierstra RD	9611183	1998
16	Molecular structures of CPF-dipeptides, inhibitors for the binding of CD4 with gp120. ³⁸	Venkatramani L...Van der Helm D	7928082	1994
17	Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. PBC1 and PBC2 trial groups. ³⁸	Christensen E...Williams R	8253362	1993
18	Evidence that rabbit cytochrome P-450 K is encoded by the plasmid pP-450 PBc2. ³⁸	Finlayson MJ...Johnson EF	3801023	1986

Sources

Genes for Biliary Cirrhosis, Primary, 2

Genes related to Biliary Cirrhosis, Primary, 2 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	PBC2	Biliary Cirrhosis, Primary, 2	Genetic Locus	58.66	Susceptibility factor ⁵⁷ GeneCards inferred via : Gene name (show sections)

Sources

Variations for Biliary Cirrhosis, Primary, 2

Sources

Expression for Biliary Cirrhosis, Primary, 2

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 2.

Sources

Pathways for Biliary Cirrhosis, Primary, 2

Sources

GO Terms for Biliary Cirrhosis, Primary, 2

Sources

Sources for Biliary Cirrhosis, Primary, 2

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ TGDB

⁷¹ Tocris

⁷² UMLS

⁷³ UMLS via Orphanet

⁷⁴ UniProtKB/Swiss-Prot

⁷⁵ Wikipedia

Biliary Cirrhosis, Primary, 2 (PBC2)

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Classifications:

External Ids:

Summaries for Biliary Cirrhosis, Primary, 2

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Biliary Cirrhosis, Primary, 2:

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Genetic Tests for Biliary Cirrhosis, Primary, 2

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

Genes for Biliary Cirrhosis, Primary, 2

Genes related to Biliary Cirrhosis, Primary, 2 (1 elite genes):

Variations for Biliary Cirrhosis, Primary, 2

Expression for Biliary Cirrhosis, Primary, 2

Pathways for Biliary Cirrhosis, Primary, 2

GO Terms for Biliary Cirrhosis, Primary, 2

Sources for Biliary Cirrhosis, Primary, 2