PBC2
MCID: BLR016
MIFTS: 17

Biliary Cirrhosis, Primary, 2 (PBC2)

Categories: Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Biliary Cirrhosis, Primary, 2

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 2:

Name: Biliary Cirrhosis, Primary, 2 57 13 72
Pbc2 57

Classifications:



External Ids:

MedGen 42 C2751696
UMLS 72 C2751696

Summaries for Biliary Cirrhosis, Primary, 2

OMIM : 57 Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (613007)

MalaCards based summary : Biliary Cirrhosis, Primary, 2, also known as pbc2, is related to primary biliary cirrhosis and biliary cirrhosis, primary, 1. An important gene associated with Biliary Cirrhosis, Primary, 2 is PBC2 (Biliary Cirrhosis, Primary, 2). Affiliated tissues include liver.

Related Diseases for Biliary Cirrhosis, Primary, 2

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1 Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3 Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 primary biliary cirrhosis 11.6
2 biliary cirrhosis, primary, 1 10.2
3 cholestasis 10.2
4 liver cirrhosis 10.2
5 primary biliary cholangitis 10.2

Graphical network of the top 20 diseases related to Biliary Cirrhosis, Primary, 2:



Diseases related to Biliary Cirrhosis, Primary, 2

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 2

Clinical features from OMIM:

613007

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 2

Search Clinical Trials , NIH Clinical Center for Biliary Cirrhosis, Primary, 2

Genetic Tests for Biliary Cirrhosis, Primary, 2

Anatomical Context for Biliary Cirrhosis, Primary, 2

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 2:

41
Liver

Publications for Biliary Cirrhosis, Primary, 2

Articles related to Biliary Cirrhosis, Primary, 2:

(show all 18)
# Title Authors PMID Year
1
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. 8
19458352 2009
2
Primary biliary cirrhosis. 8
8900092 1996
3
LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain. 38
30552194 2019
4
Odor mitigation and bacterial community dynamics in on-site biocovers at a sanitary landfill in South Korea. 38
29957505 2018
5
Chiari-related scoliosis: a single-center experience with long-term radiographic follow-up and relationship to deformity correction. 38
29171800 2018
6
A Complementary Metal Oxide Semiconductor Process-Compatible Ferroelectric Tunnel Junction. 38
28368099 2017
7
Energy Landscape of Zirconia Phase Transitions. 38
26075311 2015
8
Effective induction of pblac1 laccase by copper ion in Polyporus brumalis ibrc05015. 38
23332833 2013
9
Ferroelectricity in Simple Binary ZrO2 and HfO2. 38
22812909 2012
10
Ventral compression in adult patients with Chiari 1 malformation sans basilar invagination: cause and management. 38
22075730 2012
11
Proton dynamics in strong (short) intramolecular H-bond. DFT study of the KH maleate crystal. 38
19053812 2008
12
Structure of anhydrous alkali-metal formates. 38
16711684 2006
13
Temperature-resolved study of three [M(M'O4)4(TBPO)4] complexes (MM' = URe, ThRe, ThTc). 38
16434794 2006
14
Terephthalate salts: salts of monopositive cations 38
10877356 2000
15
Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. 38
9611183 1998
16
Molecular structures of CPF-dipeptides, inhibitors for the binding of CD4 with gp120. 38
7928082 1994
17
Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. PBC1 and PBC2 trial groups. 38
8253362 1993
18
Evidence that rabbit cytochrome P-450 K is encoded by the plasmid pP-450 PBc2. 38
3801023 1986

Variations for Biliary Cirrhosis, Primary, 2

Expression for Biliary Cirrhosis, Primary, 2

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 2.

Pathways for Biliary Cirrhosis, Primary, 2

GO Terms for Biliary Cirrhosis, Primary, 2

Sources for Biliary Cirrhosis, Primary, 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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