PBC3
MCID: BLR017
MIFTS: 11

Biliary Cirrhosis, Primary, 3 (PBC3)

Categories: Endocrine diseases, Gastrointestinal diseases, Immune diseases, Liver diseases

Aliases & Classifications for Biliary Cirrhosis, Primary, 3

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 3:

Name: Biliary Cirrhosis, Primary, 3 57 13 73
Pbc3 57

Classifications:



External Ids:

OMIM 57 613008
MedGen 42 C2751695
UMLS 73 C2751695

Summaries for Biliary Cirrhosis, Primary, 3

OMIM : 57 Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (613008)

MalaCards based summary : Biliary Cirrhosis, Primary, 3, also known as pbc3, is related to primary biliary cirrhosis. An important gene associated with Biliary Cirrhosis, Primary, 3 is PBC3 (Biliary Cirrhosis, Primary, 3). The drug Ursodeoxycholic acid has been mentioned in the context of this disorder. Affiliated tissues include liver.

Related Diseases for Biliary Cirrhosis, Primary, 3

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1 Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3 Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 3 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 primary biliary cirrhosis 11.1

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 3

Clinical features from OMIM:

613008

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 3

Drugs for Biliary Cirrhosis, Primary, 3 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial of 18-22mg/kg/d Ursodeoxycholic in Refractory Primary Biliary Cholangitis Recruiting NCT03345589 Phase 4 18-22mg/kg/d Ursodeoxycholic;13-15mg/kg/d Ursodeoxycholic

Search NIH Clinical Center for Biliary Cirrhosis, Primary, 3

Genetic Tests for Biliary Cirrhosis, Primary, 3

Anatomical Context for Biliary Cirrhosis, Primary, 3

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 3:

41
Liver

Publications for Biliary Cirrhosis, Primary, 3

Variations for Biliary Cirrhosis, Primary, 3

Expression for Biliary Cirrhosis, Primary, 3

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 3.

Pathways for Biliary Cirrhosis, Primary, 3

GO Terms for Biliary Cirrhosis, Primary, 3

Sources for Biliary Cirrhosis, Primary, 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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