Biliary Cirrhosis, Primary, 4 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Biliary Cirrhosis, Primary, 4

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 4:

Name: Biliary Cirrhosis, Primary, 4 ⁵⁶ ¹³ ⁷¹

Pbc4 ⁵⁶

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Gastrointestinal diseases Liver diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁶ 614220

OMIM Phenotypic Series ⁵⁶ PS109720

UMLS ⁷¹ C3280201

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Summaries for Biliary Cirrhosis, Primary, 4

OMIM : ⁵⁶ Primary biliary cirrhosis (PBC) is a chronic, progressive cholestatic liver disease that usually affects middle-aged women and eventually leads to liver failure (summary by Kaplan, 1996). For a discussion of genetic heterogeneity of primary biliary cirrhosis (PBC), see PBC1 (109720). (614220)

MalaCards based summary : Biliary Cirrhosis, Primary, 4, also known as pbc4, is related to primary biliary cirrhosis. An important gene associated with Biliary Cirrhosis, Primary, 4 is PBC4 (Biliary Cirrhosis, Primary, 4). Affiliated tissues include liver.

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Related Diseases for Biliary Cirrhosis, Primary, 4

Diseases in the Primary Biliary Cirrhosis family:

Biliary Cirrhosis, Primary, 1	Biliary Cirrhosis, Primary, 2
Biliary Cirrhosis, Primary, 3	Biliary Cirrhosis, Primary, 4
Biliary Cirrhosis, Primary, 5

Diseases related to Biliary Cirrhosis, Primary, 4 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	primary biliary cirrhosis	11.3

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Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 4

Clinical features from OMIM:

614220

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Drugs & Therapeutics for Biliary Cirrhosis, Primary, 4

Search Clinical Trials , NIH Clinical Center for Biliary Cirrhosis, Primary, 4

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Genetic Tests for Biliary Cirrhosis, Primary, 4

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Anatomical Context for Biliary Cirrhosis, Primary, 4

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 4:

⁴⁰

Liver

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Publications for Biliary Cirrhosis, Primary, 4

Articles related to Biliary Cirrhosis, Primary, 4:

#	Title	Authors	PMID	Year
1	Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. ⁵⁶	Hirschfield GM...Siminovitch KA	20639879	2010
2	Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. ⁵⁶	Liu X...Seldin MF	20639880	2010
3	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. ⁵⁶	Hirschfield GM...Siminovitch KA	19458352	2009
4	Primary biliary cirrhosis. ⁵⁶	Kaplan MM	8900092	1996
5	Genomic characterization of three novel Basilisk-like phages infecting Bacillus anthracis. ⁶¹	Farlow J...Kutateladze M	30227847	2018
6	Characterization of LysPBC4, a novel Bacillus cereus-specific endolysin of bacteriophage PBC4. ⁶¹	Na H...Ryu S	27190165	2016

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Genes for Biliary Cirrhosis, Primary, 4

Genes related to Biliary Cirrhosis, Primary, 4 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	PBC4	Biliary Cirrhosis, Primary, 4	Genetic Locus	58.52	Genetic linkage ⁵⁶ GeneCards inferred via : Gene name (show sections)

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Variations for Biliary Cirrhosis, Primary, 4

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Expression for Biliary Cirrhosis, Primary, 4

Search GEO for disease gene expression data for Biliary Cirrhosis, Primary, 4.

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Pathways for Biliary Cirrhosis, Primary, 4

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GO Terms for Biliary Cirrhosis, Primary, 4

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Sources for Biliary Cirrhosis, Primary, 4

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Biliary Cirrhosis, Primary, 4 (PBC4)

Aliases & Classifications for Biliary Cirrhosis, Primary, 4

MalaCards integrated aliases for Biliary Cirrhosis, Primary, 4:

Classifications:

External Ids:

Summaries for Biliary Cirrhosis, Primary, 4

Related Diseases for Biliary Cirrhosis, Primary, 4

Diseases in the Primary Biliary Cirrhosis family:

Diseases related to Biliary Cirrhosis, Primary, 4 via text searches within MalaCards or GeneCards Suite gene sharing:

Symptoms & Phenotypes for Biliary Cirrhosis, Primary, 4

Clinical features from OMIM:

Drugs & Therapeutics for Biliary Cirrhosis, Primary, 4

Genetic Tests for Biliary Cirrhosis, Primary, 4

Anatomical Context for Biliary Cirrhosis, Primary, 4

MalaCards organs/tissues related to Biliary Cirrhosis, Primary, 4:

Publications for Biliary Cirrhosis, Primary, 4

Articles related to Biliary Cirrhosis, Primary, 4:

Genes for Biliary Cirrhosis, Primary, 4

Genes related to Biliary Cirrhosis, Primary, 4 (1 elite genes):

Variations for Biliary Cirrhosis, Primary, 4

Expression for Biliary Cirrhosis, Primary, 4

Pathways for Biliary Cirrhosis, Primary, 4

GO Terms for Biliary Cirrhosis, Primary, 4

Sources for Biliary Cirrhosis, Primary, 4