MCID: BLR006
MIFTS: 52

Biliary Tract Disease

Categories: Gastrointestinal diseases

Aliases & Classifications for Biliary Tract Disease

MalaCards integrated aliases for Biliary Tract Disease:

Name: Biliary Tract Disease 12 15 17
Biliary Tract Diseases 45 74
Biliary Tract Abnormality 30

Classifications:



External Ids:

Disease Ontology 12 DOID:9741
ICD9CM 36 576.9
MeSH 45 D001660
SNOMED-CT 69 5235004
ICD10 34 K83.8 K83.9
UMLS 74 C0005424

Summaries for Biliary Tract Disease

MalaCards based summary : Biliary Tract Disease, also known as biliary tract diseases, is related to obstructive jaundice and cholecystitis, and has symptoms including digestive system symptom An important gene associated with Biliary Tract Disease is NR1H4 (Nuclear Receptor Subfamily 1 Group H Member 4), and among its related pathways/superpathways are Synthesis of bile acids and bile salts and NRF2 pathway. The drugs Vancomycin and Nefopam have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and lung, and related phenotypes are homeostasis/metabolism and liver/biliary system

Related Diseases for Biliary Tract Disease

Diseases related to Biliary Tract Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
# Related Disease Score Top Affiliating Genes
1 obstructive jaundice 30.6 ALB GGT1 GPT SLC25A13
2 cholecystitis 30.6 ABCB4 ALB CCK GPT
3 cholangitis 30.4 ABCB11 ABCB4 ALB GGT1 GPT
4 sclerosing cholangitis 30.2 ABCB11 ABCB4 ALB GGT1 NR1H4 NR1I2
5 cholelithiasis 30.1 ABCB4 ALB CCK CYP7A1 GPT NR1H4
6 biliary atresia 29.9 ALB ATP8B1 GPT KRT7 NR1H4 SLC10A1
7 cholangitis, primary sclerosing 29.8 ABCB4 ALB GGT1 GPT KRT19 NR1I2
8 autosomal dominant non-syndromic intellectual disability 2 10.5 NR1I2 NR1I3
9 autosomal dominant non-syndromic intellectual disability 3 10.5 NR1I2 NR1I3
10 cholestasis, progressive familial intrahepatic, 5 10.5 NR1H4 NR1I2 NR1I3
11 atp8b1 deficiency 10.5 ABCB11 ATP8B1 NR1H4
12 cholestasis, progressive familial intrahepatic, 4 10.4 ABCB11 ABCB4 ATP8B1
13 cerebrotendinous xanthomatosis 10.4 CYP7A1 NR1H4 NR1I2
14 cholestasis, progressive familial intrahepatic, 3 10.4 ABCB11 ABCB4 ATP8B1
15 alagille syndrome 1 10.4 ABCB11 ABCB4 ATP8B1
16 cholestasis, benign recurrent intrahepatic, 1 10.4 ABCB11 ATP8B1 SLC10A1
17 cyclosporiasis 10.4 GGT1 GGT2
18 cholecystolithiasis 10.4 ABCB4 CCK
19 intrahepatic bile duct adenoma 10.4 KRT19 KRT7
20 choledocholithiasis 10.4 ABCB4 ALB GPT
21 anal gland adenocarcinoma 10.4 KRT19 KRT7
22 algoneurodystrophy 10.4 GGT1 GGT2
23 proliferating trichilemmal cyst 10.4 KRT19 KRT7
24 hyperbilirubinemia, rotor type 10.4 ABCC2 ALB
25 anus adenocarcinoma 10.4 KRT19 KRT7
26 periampullary adenoma 10.4 GGT1 GGT2
27 cholestasis, progressive familial intrahepatic, 2 10.4 ABCB11 ABCB4 ATP8B1 NR1H4
28 renal pelvis adenocarcinoma 10.4 KRT19 KRT7
29 cholestasis, progressive familial intrahepatic, 1 10.4 ABCB11 ABCB4 ATP8B1 NR1H4
30 hepatic encephalopathy 10.4 ALB GPT SLC25A13
31 pancreatic cystadenocarcinoma 10.4 GGT1 GGT2
32 cutaneous adenocystic carcinoma 10.4 KRT19 KRT7
33 ethmoid sinus cancer 10.4 GGT1 GGT2
34 ethmoid sinus adenocarcinoma 10.4 GGT1 GGT2
35 kwashiorkor 10.3 ALB GPT
36 bladder carcinoma in situ 10.3 KRT19 KRT7
37 hepatic coma 10.3 ALB GPT
38 viral hepatitis 10.3 ALB GGT1 GPT
39 malignant leydig cell tumor 10.3 KRT19 KRT7
40 common bile duct disease 10.3 CCK GGT2
41 corneal abscess 10.3 KRT19 KRT7
42 nasal cavity adenocarcinoma 10.3 CCK KRT7
43 bile duct adenocarcinoma 10.3 KRT19 KRT7 PRRT2
44 eccrine adenocarcinoma 10.3 KRT19 KRT7
45 infantile liver failure syndrome 1 10.3 ALB GPT
46 gastrointestinal system cancer 10.3 ALB KRT19 KRT7
47 colloid carcinoma of the pancreas 10.3 GGT1 GGT2 KRT19
48 progressive familial intrahepatic cholestasis 10.3 ABCB11 ABCB4 ABCC2 ATP8B1 NR1H4
49 hepatitis b 10.3 ALB GGT1 GPT SLC10A1
50 anal canal adenocarcinoma 10.2 KRT19 KRT7

Comorbidity relations with Biliary Tract Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Pancreatitis

Graphical network of the top 20 diseases related to Biliary Tract Disease:



Diseases related to Biliary Tract Disease

Symptoms & Phenotypes for Biliary Tract Disease

UMLS symptoms related to Biliary Tract Disease:


digestive system symptom

MGI Mouse Phenotypes related to Biliary Tract Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10 ABCB11 ABCB4 ABCC2 ABCC4 ALB ATP8B1
2 liver/biliary system MP:0005370 9.65 ABCB11 ABCB4 ABCC2 ALB ATP8B1 CYP7A1
3 renal/urinary system MP:0005367 9.17 ABCC2 ABCC4 ALB CCK GGT1 KRT7

Drugs & Therapeutics for Biliary Tract Disease

Drugs for Biliary Tract Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 544)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vancomycin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1404-90-6 14969 441141
2
Nefopam Approved, Investigational Phase 4 13669-70-0
3
Ketamine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 6740-88-1 3821
4
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
5
Benzocaine Approved, Investigational Phase 4,Phase 2,Not Applicable 1994-09-7, 94-09-7 2337
6
tannic acid Approved Phase 4,Phase 2,Not Applicable 1401-55-4
7
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 2078-54-8 4943
8
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
9
Dopamine Approved Phase 4,Phase 3 62-31-7, 51-61-6 681
10
Droperidol Approved, Vet_approved Phase 4 548-73-2 3168
11
Gabapentin Approved, Investigational Phase 4,Phase 3 60142-96-3 3446
12
Esketamine Approved, Investigational Phase 4 33643-46-8
13 Pinaverium Approved Phase 4,Not Applicable 59995-65-2
14
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 175805 71273
15
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
16
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
17
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
18
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
19
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
20
Etomidate Approved Phase 4 33125-97-2 667484 36339
21
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
22
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
23
Pancrelipase Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 53608-75-6
24
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
25
Ursodeoxycholic acid Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 128-13-2 31401
26
chenodeoxycholic acid Approved Phase 4,Phase 3,Phase 2,Early Phase 1 474-25-9 10133
27
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
28
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 437-38-7 3345
29
Acetaminophen Approved Phase 4 103-90-2 1983
30
Ibuprofen Approved Phase 4,Not Applicable 15687-27-1 3672
31
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
32
Meperidine Approved Phase 4,Not Applicable 57-42-1 4058
33
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613
34
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
35
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
36
Granisetron Approved, Investigational Phase 4 109889-09-0 3510
37
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
38
Neostigmine Approved, Vet_approved Phase 4,Not Applicable 59-99-4 4456
39
Ondansetron Approved Phase 4 99614-02-5 4595
40
Morphine Approved, Investigational Phase 4,Phase 2,Not Applicable 57-27-2 5288826
41
Ketorolac Approved Phase 4,Not Applicable 74103-06-3, 66635-83-4 3826
42
Ephedrine Approved Phase 4,Not Applicable 299-42-3 9294
43
Pseudoephedrine Approved Phase 4,Not Applicable 90-82-4 7028
44
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 38396-39-3, 2180-92-9 2474
45
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
46
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
47
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 443-48-1 4173
48
Secretin Approved Phase 4 108153-74-8
49
Abatacept Approved Phase 4 332348-12-6 10237
50
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619

Interventional clinical trials:

(show top 50) (show all 1109)
# Name Status NCT ID Phase Drugs
1 Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis Patients Unknown status NCT02605213 Phase 4 Vancomycin;Placebo
2 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
3 Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA) Unknown status NCT01126281 Phase 4
4 Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy Unknown status NCT02114437 Phase 4
5 The Discovery of the Double Sphincter in Gallbladder Unknown status NCT01998451 Phase 4 Tauroursodeoxycholic acid
6 Laparo-endoscopic Single Site (LESS) Cholecystectomy Versus Standard LAP-CHOLE Unknown status NCT01339325 Phase 4
7 Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized Controlled Trial. Unknown status NCT01052727 Phase 4
8 Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy Unknown status NCT00209885 Phase 4 Gabapentin;S-ketamine;Lidocaine;Droperidol
9 Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla Unknown status NCT02703077 Phase 4
10 Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction Unknown status NCT02833103 Phase 4 Danshu Capsules;Pinaverium Bromide
11 Uncovered Self-expandable Metal Stent Versus Double Layer Plastic Stent for Malignant Hilar Stricture Unknown status NCT01125865 Phase 4
12 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
13 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4 etomidate;midazolam;propofol
14 Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery Unknown status NCT02174575 Phase 4 Sevoflurane;Desflurane
15 Efficacy and Safety of S-adenosyl-l-methionine in Treatment of Alcoholic Hepatitis With Cholestasis Unknown status NCT02024295 Phase 4 Ademethionine;Polyene Phosphatidyl choline;Ademethionine
16 Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis Unknown status NCT01998620 Phase 4 Ademetionine 2;Ademetionine 1;Ademetionine 3
17 Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy Unknown status NCT01969110 Phase 4
18 Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy Unknown status NCT01256047 Phase 4
19 Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer Unknown status NCT01111591 Phase 4 Cox2 inhibitor (Celecoxib)
20 Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Unknown status NCT00792389 Phase 4
21 Spy II Clinical Registry Completed NCT00751998 Phase 4
22 Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01350037 Phase 4 alfentanil;remifentanil
23 Effect IV Ibuprofen and Inflammatory Responses Completed NCT01938040 Phase 4 ibuprofen
24 The Usefulness of Endoscopic Ultrasound-guided Biliary Drainage With a Newly Designed Hybrid Metallic Stent Completed NCT01862198 Phase 4
25 A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982) Completed NCT01728584 Phase 4 Rocuronium;Sugammadex
26 Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Completed NCT01709422 Phase 4 Propofol;Midazolam;Meperidine
27 Cocktail Sedation Containing Propofol Versus Conventional Sedation for Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01540084 Phase 4 propofol
28 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Completed NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
29 Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
30 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
31 Vitamin C Efficacy in Reducing Post Operative Pain Completed NCT01322061 Phase 4 Ascorbic Acid
32 LaGRA Trial in Laparoscopic Cholecystectomy Completed NCT03394807 Phase 4 Levobupivacaine;Placebo
33 Granisetron Effect on Hemodynamic Changes in Laparoscopic Cholecystectomy Completed NCT03180229 Phase 4 Granisetron 1 Mg/mL Intravenous Solution
34 Endovenous Lidocaine and Serum Cytokines Concentration Completed NCT02363699 Phase 4 Lidocaine;Saline solution
35 Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy Completed NCT02327923 Phase 4 Lidocaine;Esmolol;Paracetamol;Lidocaine;Propofol;Fentanyl;Vecuronium;Atropine;Ephedrine;Morphine;Ketorolac;Ondansetron;Bupivacaine;Tramadol;Neostigmine;Glycopyrrolate
36 Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI) Completed NCT02116985 Phase 4
37 Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy Completed NCT01397565 Phase 4
38 Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy Completed NCT01211743 Phase 4
39 Clinical Study About the Role of COX-2 Inhibitor in Liver Cirrhosis With Biliary Atresia Completed NCT02298218 Phase 4 Meloxicam
40 Multi-Port Versus Single-port Cholecystectomy Completed NCT01104727 Phase 4
41 Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy Completed NCT01103570 Phase 4
42 Levobupivacaine During Cholecystectomy Completed NCT00836316 Phase 4 levobupivacaine
43 Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study Completed NCT00562900 Phase 4
44 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
45 Effect of Rowachol on Prevention of Postcholecystectomy Syndrome Completed NCT01765465 Phase 4 Rowachol;Placebo
46 Radiofrequency Ablation for Malignant Biliary Obstruction Completed NCT01758341 Phase 4
47 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
48 A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers Completed NCT01134848 Phase 4 Morphine;Neostigmine;0.9% saline;Secretin;0.9% saline
49 Preventing Cholestasis Using SMOFLipid® Completed NCT01585935 Phase 4 SMOFLIPID;INTRALIPID
50 Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis Completed NCT02557360 Phase 4

Search NIH Clinical Center for Biliary Tract Disease

Cochrane evidence based reviews: biliary tract diseases

Genetic Tests for Biliary Tract Disease

Genetic tests related to Biliary Tract Disease:

# Genetic test Affiliating Genes
1 Biliary Tract Abnormality 30

Anatomical Context for Biliary Tract Disease

MalaCards organs/tissues related to Biliary Tract Disease:

42
Liver, Pancreas, Lung, Testes, T Cells, Bone, Nk Cells

Publications for Biliary Tract Disease

Articles related to Biliary Tract Disease:

(show top 50) (show all 342)
# Title Authors Year
1
Biliary Tract Disease in Girls and Young Women with Rett Syndrome. ( 30664568 )
2019
2
Colonization, resistance to bile, and virulence properties of Escherichia coli strains: Unusual characteristics associated with biliary tract diseases. ( 28867623 )
2017
3
Single-incision laparoscopic surgery for biliary tract disease. ( 26811621 )
2016
4
Risk and Surveillance of Cancers in Primary Biliary Tract Disease. ( 27413366 )
2016
5
Association of Statin Therapy and Risks of Cholelithiasis, Biliary Tract Diseases, and Gallbladder Procedures: Retrospective Cohort Analysis of a US Population. ( 26706861 )
2016
6
Primary Sclerosing Cholangitis as a Premalignant Biliary Tract Disease: Surveillance and Management. ( 26051390 )
2015
7
Novel Serum Biomarkers to Differentiate Cholangiocarcinoma from Benign Biliary Tract Diseases Using a Proteomic Approach. ( 26060332 )
2015
8
Type II diabetes mellitus is associated with a reduced risk of cholangiocarcinoma in patients with biliary tract diseases. ( 25348605 )
2015
9
Recurrent pyogenic cholangitis as a differential diagnosis in biliary tract diseases. ( 26367025 )
2015
10
MicroRNAs and benign biliary tract diseases. ( 25632932 )
2015
11
Asbestos fibers in the gallbladder of patients affected by benign biliary tract diseases. ( 25856690 )
2015
12
Current status of peroral cholangioscopy in biliary tract diseases. ( 25992189 )
2015
13
Advanced Imaging Technology in Biliary Tract Diseases:Narrow-Band Imaging of the Bile Duct. ( 26668795 )
2015
14
Body mass index and biliary tract disease: a systematic review and meta-analysis of prospective studies. ( 24721739 )
2014
15
Ketamine abuse, biliary tract disease, and secondary sclerosing cholangitis. ( 23695896 )
2013
16
Impact of an acute care surgery model with a dedicated daytime operating room on outcomes and timeliness of care in patients with biliary tract disease. ( 23756774 )
2013
17
Endoscopic diagnosis of biliary tract disease. ( 22343346 )
2012
18
Transgastric endoscopic retrograde cholangiopancreatography for the management of biliary tract disease after Roux-en-Y gastric bypass treatment for obesity. ( 22460551 )
2012
19
Cholangioscopy using a new type of cholangioscope for the diagnosis of biliary tract disease: a case series. ( 22814962 )
2012
20
Role of intraoperative flexible Choledochoscopy in calculous biliary tract disease. ( 22828544 )
2012
21
Lack of association between Helicobacter pylori infection and biliary tract diseases. ( 23484417 )
2012
22
Novel biopsy forceps for diagnosis of biliary tract diseases during endoscopic retrograde cholangiopancreatography: a prospective comparative study with 90° adjustable and conventional biopsy forceps. ( 22094996 )
2012
23
Prognostic relevance of circulating CK19 mRNA in advanced malignant biliary tract diseases. ( 22253524 )
2012
24
A stunning year for advances in biliary tract disease. ( 21423005 )
2011
25
Peroral cholangioscopy for diagnosis and therapy of biliary tract disease using an ultra-slim gastroscope. ( 21823068 )
2011
26
Imaging of biliary tract disease. ( 21940525 )
2011
27
Covered self-expandable metal stents for benign biliary tract diseases. ( 21248636 )
2011
28
Successful off-label use of enteral stents in uncommon complicated biliary tract diseases. ( 21457820 )
2011
29
Serum NGAL to Clinically Distinguish Cholangiocarcinoma from Benign Biliary Tract Diseases. ( 21994874 )
2011
30
Vascular factors, angiogenesis and biliary tract disease. ( 20061944 )
2010
31
Endoscopic retrograde cholangiopancreatography in pancreatic and biliary tract disease in Korean children. ( 20101777 )
2010
32
Management of biliary tract disease during pregnancy. ( 20193902 )
2010
33
Farnesoid X receptor agonists in biliary tract disease. ( 19300246 )
2009
34
Minimally invasive management of acute biliary tract disease during pregnancy. ( 19606252 )
2009
35
The role of international classification of diseases in assessment of patients with biliary tract disease. ( 19745312 )
2009
36
Management of biliary tract disease during pregnancy: a decision analysis. ( 17713817 )
2008
37
Chlamydia infection as risk factor for pediatric biliary tract disease. ( 18334886 )
2008
38
Double-balloon enteroscopy application in biliary tract disease-its therapeutic and diagnostic functions. ( 18561917 )
2008
39
Novel endoscopic approaches for assessing biliary tract diseases. ( 18408465 )
2008
40
Genetics of biliary tract diseases: new insights into gallstone disease and biliary tract cancers. ( 18408466 )
2008
41
Peroral cholangioscopic diagnosis of biliary-tract diseases by using narrow-band imaging (with videos). ( 17905015 )
2007
42
Endoscopic treatment of biliary tract disease prior to orthotopic liver transplantation. ( 16539874 )
2006
43
Liver transplantation in precirrhotic biliary tract disease: Portal hypertension is frequently associated with nodular regenerative hyperplasia and obliterative portal venopathy. ( 17063088 )
2006
44
Biliary tract disease as a risk factor for Plesiomonas shigelloides bacteraemia: a nine-year experience in a Hong Kong hospital and review of the literature. ( 15782626 )
2005
45
A bile based study of Clonorchis sinensis infections in patients with biliary tract diseases in Ulsan, Korea. ( 16385655 )
2005
46
Bacteriuria in patients with gallbladder and biliary tract diseases. ( 16295397 )
2004
47
Medical versus surgical management of biliary tract disease in pregnancy. ( 15619495 )
2004
48
Reoperation for benign biliary tract diseases in 149 cases: causes and prevention. ( 15138123 )
2004
49
C-reactive protein in patients with gallbladder and biliary tract diseases. ( 15471320 )
2004
50
Gallbladder and biliary tract disease in the intensive care unit. ( 12610852 )
2003

Variations for Biliary Tract Disease

Expression for Biliary Tract Disease

Search GEO for disease gene expression data for Biliary Tract Disease.

Pathways for Biliary Tract Disease

Pathways related to Biliary Tract Disease according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.96 ABCB11 ALB CYP7A1 NR1H4 SLC10A1
2 11.87 ABCC2 ABCC4 GGT1 GGT2
3
Show member pathways
11.76 ABCB11 ABCB4 ABCC2 SLC10A1
4
Show member pathways
11.69 ABCB11 ABCC2 ABCC4
5
Show member pathways
11.61 NR1H4 NR1I2 NR1I3
6 11.56 ABCB11 ABCB4 ABCC2 ABCC4 CYP7A1 NR1H4
7
Show member pathways
11.42 ABCC2 NR1I2 NR1I3
8 11.04 ABCB11 ABCB4 ABCC2 CYP7A1 NR1H4 NR1I2
9 10.93 ABCB11 ABCB4 CYP7A1 NR1H4 SLC10A1
10 10.9 GGT1 GGT2
11
Show member pathways
10.83 ABCC2 ABCC4
12 10.77 ABCC2 ABCC4
13 10.61 ABCC2 NR1I2
14 10.46 ABCB11 ABCC2 ABCC4 CYP7A1 NR1H4 NR1I2

GO Terms for Biliary Tract Disease

Cellular components related to Biliary Tract Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.61 ABCB11 ABCB4 ALB GGT1 GGT2 GGTLC3
2 RNA polymerase II transcription factor complex GO:0090575 9.33 NR1H4 NR1I2 NR1I3
3 intercellular canaliculus GO:0046581 8.8 ABCB11 ABCB4 ABCC2

Biological processes related to Biliary Tract Disease according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.85 ABCB11 ABCB4 ABCC2 ABCC4 SLC10A1 SLC25A13
2 steroid hormone mediated signaling pathway GO:0043401 9.65 NR1H4 NR1I2 NR1I3
3 intracellular receptor signaling pathway GO:0030522 9.58 NR1H4 NR1I2 NR1I3
4 glutamate metabolic process GO:0006536 9.56 GGT1 GGT2
5 zymogen activation GO:0031638 9.55 GGT1 GGT2
6 bile acid metabolic process GO:0008206 9.54 ATP8B1 NR1H4
7 cysteine biosynthetic process GO:0019344 9.52 GGT1 GGT2
8 regulation of immune system process GO:0002682 9.49 GGT1 GGT2
9 canalicular bile acid transport GO:0015722 9.46 ABCB11 ABCC2
10 regulation of bile acid biosynthetic process GO:0070857 9.43 CYP7A1 NR1H4
11 glutathione catabolic process GO:0006751 9.33 GGT1 GGT2 GGTLC3
12 peptide modification GO:0031179 9.32 GGT1 GGT2
13 drug transmembrane transport GO:0006855 9.26 ABCC2 ATP8B1
14 xenobiotic transport GO:0042908 9.21 NR1I2
15 leukotriene D4 biosynthetic process GO:1901750 9.13 GGT1 GGT2 GGTLC3
16 bile acid and bile salt transport GO:0015721 8.92 ABCB11 ATP8B1 NR1H4 SLC10A1

Molecular functions related to Biliary Tract Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATPase activity GO:0016887 9.73 ABCB11 ABCB4 ABCC2 ABCC4
2 transcription regulatory region sequence-specific DNA binding GO:0000976 9.58 NR1H4 NR1I2 NR1I3
3 nuclear receptor transcription coactivator activity GO:0030374 9.54 NR1H4 NR1I2 NR1I3
4 steroid hormone receptor activity GO:0003707 9.5 NR1H4 NR1I2 NR1I3
5 nuclear receptor activity GO:0004879 9.33 NR1H4 NR1I2 NR1I3
6 peptidyltransferase activity GO:0000048 9.26 GGT1 GGT2
7 ATPase activity, coupled to transmembrane movement of substances GO:0042626 9.26 ABCB11 ABCB4 ABCC2 ABCC4
8 glutathione hydrolase activity GO:0036374 8.8 GGT1 GGT2 GGTLC3

Sources for Biliary Tract Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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