MCID: BLR008
MIFTS: 55

Bilirubin Metabolic Disorder

Categories: Blood diseases, Metabolic diseases

Aliases & Classifications for Bilirubin Metabolic Disorder

MalaCards integrated aliases for Bilirubin Metabolic Disorder:

Name: Bilirubin Metabolic Disorder 12 15
Hyperbilirubinemia 12 76 37 29 55 6 44 15 73
Hyperbilirubinemia, Hereditary 44 73
Hereditary Hyperbilirubinemia 12
Hyperbilirubinaemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2741
NCIt 50 C84761
SNOMED-CT 68 14783006 20505009
KEGG 37 H00208
ICD10 33 E80.6

Summaries for Bilirubin Metabolic Disorder

Disease Ontology : 12 An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.

MalaCards based summary : Bilirubin Metabolic Disorder, also known as hyperbilirubinemia, is related to hyperbilirubinemia, rotor type and obstructive jaundice, and has symptoms including muscle weakness, polydipsia and icterus. An important gene associated with Bilirubin Metabolic Disorder is UGT1A1 (UDP Glucuronosyltransferase Family 1 Member A1), and among its related pathways/superpathways are Porphyrin and chlorophyll metabolism and ABC transporters. Affiliated tissues include liver, testes and bone, and related phenotype is homeostasis/metabolism.

Wikipedia : 76 Bilirubin is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in... more...

Related Diseases for Bilirubin Metabolic Disorder

Diseases related to Bilirubin Metabolic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 242)
# Related Disease Score Top Affiliating Genes
1 hyperbilirubinemia, rotor type 34.3 ABCC2 ALB SLCO1B1
2 obstructive jaundice 31.8 ALB F2 GGT1 GPT SLC17A5
3 gilbert syndrome 31.7 G6PD SLCO1B1 UGT1A1 UGT1A6 UGT1A7
4 crigler-najjar syndrome, type ii 31.6 UGT1A UGT1A1 UGT1A6 UGT1A7
5 crigler-najjar syndrome, type i 31.5 SLC35A2 UGT1A UGT1A1 UGT1A6
6 kernicterus 30.5 ALB G6PD PKM UGT1A1 UGT1A6
7 glucosephosphate dehydrogenase deficiency 30.4 G6PD HP SLCO1B1 UGT1A1
8 neonatal jaundice 30.3 G6PD HMOX1 NR1I3 SLCO1B1 UGT1A1
9 hepatitis a 30.2 ALB F2 GPT
10 cholelithiasis 30.0 ALB GPT UGT1A1 UGT1A6
11 infantile liver failure syndrome 1 29.9 ALB F2 GPT SLC17A5
12 cholestasis 29.9 ABCC2 F2 GGT1 GPT NR1I3 SLCO1B1
13 cholecystitis 29.9 ALB F2 GPT HP
14 hepatic coma 29.8 ALB F2 GPT
15 hemorrhagic fever 29.8 ALB F2 GPT
16 hepatitis e 29.8 ALB F2 GPT
17 alpha-thalassemia 29.7 G6PD HP UGT1A1
18 pyruvate kinase deficiency of red cells 29.7 G6PD PKM
19 sickle cell anemia 29.7 F2 G6PD UGT1A1 UGT1A6
20 nonalcoholic steatohepatitis 29.7 F2 GPT SLC17A5
21 hepatitis 29.6 F2 GGT1 GPT SLC17A5
22 alcoholic hepatitis 29.6 ADAMTS13 ALB F2 GPT SLC17A5
23 viral hepatitis 29.6 ALB F2 GGT1 GPT SLC17A5
24 analbuminemia 29.6 ALB F2 GPT SLC17A5
25 acute liver failure 29.6 ALB F2 GPT SLC17A5
26 liver disease 29.5 ALB F2 GGT1 GPT SLC17A5
27 primary biliary cirrhosis 29.4 ALB F2 GGT1
28 hepatitis b 29.3 ALB F2 GGT1 GPT SLC17A5
29 liver cirrhosis 29.3 ALB F2 GGT1 GPT SLC17A5
30 hyperbilirubinemia, transient familial neonatal 12.5
31 hyperbilirubinemia, shunt, primary 12.3
32 hyperbilirubinemia, conjugated, type iii 12.0
33 liver failure, infantile, transient 11.2
34 congenital intrauterine infection-like syndrome 11.1
35 bamforth syndrome 11.1
36 dubin-johnson syndrome 11.1
37 cryohydrocytosis 11.0
38 biliary atresia, extrahepatic 11.0
39 bile acid synthesis defect, congenital, 1 11.0
40 stomatin-deficient cryohydrocytosis with neurologic defects 11.0
41 obesity, early-onset, with adrenal insufficiency and red hair 11.0
42 congenital toxoplasmosis 11.0
43 antipyrine metabolism 10.3 ALB F2
44 non-a-e hepatitis 10.3 ALB F2
45 epstein-barr virus hepatitis 10.3 ALB F2
46 fournier gangrene 10.2 ALB F2
47 heme oxygenase 1 deficiency 10.2 HMOX1 HP
48 abdominal tuberculosis 10.2 ALB F2
49 hepatoportal sclerosis 10.2 F2 GPT
50 intracranial embolism 10.2 F12 F2

Graphical network of the top 20 diseases related to Bilirubin Metabolic Disorder:



Diseases related to Bilirubin Metabolic Disorder

Symptoms & Phenotypes for Bilirubin Metabolic Disorder

UMLS symptoms related to Bilirubin Metabolic Disorder:


muscle weakness, polydipsia, icterus, jaundice (not of newborn)

MGI Mouse Phenotypes related to Bilirubin Metabolic Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.4 ABCC2 ADAMTS13 ALB F12 F2 G6PD

Drugs & Therapeutics for Bilirubin Metabolic Disorder

Search Clinical Trials , NIH Clinical Center for Bilirubin Metabolic Disorder

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: hyperbilirubinemia

Genetic Tests for Bilirubin Metabolic Disorder

Genetic tests related to Bilirubin Metabolic Disorder:

# Genetic test Affiliating Genes
1 Hyperbilirubinemia 29

Anatomical Context for Bilirubin Metabolic Disorder

MalaCards organs/tissues related to Bilirubin Metabolic Disorder:

41
Liver, Testes, Bone, Heart, Myeloid, Lung, Colon

Publications for Bilirubin Metabolic Disorder

Articles related to Bilirubin Metabolic Disorder:

(show top 50) (show all 787)
# Title Authors Year
1
Probiotics for the management of neonatal hyperbilirubinemia: a systematic review of randomized controlled trials. ( 28823200 )
2019
2
Role of massage therapy on reduction of neonatal hyperbilirubinemia in term and preterm neonates: a review of clinical trials. ( 28870134 )
2019
3
Acute liver failure with extreme hyperbilirubinemia secondary to endocarditis-related severe mitral and tricuspid regurgitation: a challenge and an opportunity for surgeons. ( 29607182 )
2018
4
A Prospective Study on the Diagnostic Value of Hyperbilirubinemia as a Predictive Factor for Appendicular Perforation in Acute Appendicitis. ( 30405990 )
2018
5
Hyperbilirubinemia, Phototherapy, and Childhood Asthma. ( 30209075 )
2018
6
Clinical Value of Inflammation-Based Prognostic Scores to Predict the Resectability of Hyperbilirubinemia Patients with Potentially Resectable Hilar Cholangiocarcinoma. ( 30076591 )
2018
7
Vitamin B12 deficiency associated with hyperbilirubinemia and cholestasis in infants. ( 30034445 )
2018
8
Adding neonatal hyperbilirubinemia/bilirubin encephalopathy to the American Society for Apheresis Guidelines on Therapeutic Apheresis. ( 29193228 )
2018
9
Adding neonatal hyperbilirubinemia/bilirubin encephalopathy to the American Society for Apheresis Guidelines on Therapeutic Apheresis. ( 29193232 )
2018
10
Direct hyperbilirubinemia in newborns with gastroschisis. ( 30415437 )
2018
11
An unexpectedly prolonged severe hyperbilirubinemia in a patient with pre-existing hepatitis A: a role of genetic predisposition? ( 30422796 )
2018
12
Tokyo-1 Mutation: Hereditary Spherocytosis in a Hispanic Newborn Presenting as Early Onset Severe Hyperbilirubinemia. ( 30207817 )
2018
13
Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus. ( 30369069 )
2018
14
Letter: tacrolimus may be hazardous in decompensated autoimmune liver disease with hyperbilirubinemia-authors' reply. ( 29878432 )
2018
15
Phototherapy for neonatal hyperbilirubinemia and childhood eczema, rhinitis and wheeze. ( 29678409 )
2018
16
Risk Factors for Sensorineural Hearing Loss in Neonatal Hyperbilirubinemia. ( 30083525 )
2018
17
Brief Report: Hyperbilirubinemia Is Associated With a Decreased Risk of Carotid Atherosclerosis in HIV-Infected Patients on Virological Suppression. ( 30204718 )
2018
18
Effect of Hyperbilirubinemia on Hepatic Hypertrophy after Portal Vein Embolization and Liver Failure after Heatectomy in Primary Biliary Malignancy. ( 30527653 )
2018
19
Severe neonatal hyperbilirubinemia induces temporal and occipital lobe seizures. ( 29750802 )
2018
20
Intraoperative Phototherapy for Hyperbilirubinemia. ( 29035896 )
2018
21
Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia. ( 29059457 )
2018
22
Double versus single intensive phototherapy with LEDs in treatment of neonatal hyperbilirubinemia. ( 29095431 )
2018
23
Urinary tract infections in neonates with unexplained pathological indirect hyperbilirubinemia: Prevalence and significance. ( 29150336 )
2018
24
Direct hyperbilirubinemia in infants with congenital heart disease. ( 29178522 )
2018
25
Neonatal hyperbilirubinemia secondary to combined anti e and anti C isoimmunisation: a literature review. ( 29295661 )
2018
26
Heme oxygenase-1 genetic variants and the conundrum of hyperbilirubinemia in African-American newborns. ( 29302043 )
2018
27
"Gilbert's-like" syndrome as part of a spectrum of persistent unconjugated hyperbilirubinemia in post-chronic hepatitis patients. ( 29386646 )
2018
28
Effectiveness of universal hyperbilirubinemia screening on newborn health: a systematic review protocol. ( 29419612 )
2018
29
Prediction of Neonatal Hyperbilirubinemia Using 1st Day Serum Bilirubin Levels. ( 29450817 )
2018
30
Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia. ( 29458193 )
2018
31
Incidence and risk factors of post-phototherapy neonatal rebound hyperbilirubinemia. ( 29464578 )
2018
32
Hyperbilirubinemia-induced pro-angiogenic activity of infantile endothelial progenitor cells. ( 29476756 )
2018
33
Phone app detects hyperbilirubinemia. ( 29478501 )
2018
34
Significant Hyperbilirubinemia and Acute Hepatocellular Jaundice in a Pediatric Patient Receiving Deferasirox: A Case Report. ( 29491755 )
2018
35
UGT1A1 gene and neonatal hyperbilirubinemia: a preliminary study from Bengkulu, Indonesia. ( 29534743 )
2018
36
L-carnitine and Vitamin B Complex for the Treatment of Pegasparaginase-induced Hyperbilirubinemia. ( 29550108 )
2018
37
Unconjugated hyperbilirubinemia in a blood donor: Chance finding due to unusual plasma discoloration. ( 29563668 )
2018
38
Conjugated Hyperbilirubinemia in the Neonate and Young Infant. ( 29601463 )
2018
39
Conjugated Hyperbilirubinemia in the Neonate and Young Infant. ( 29601464 )
2018
40
The accuracy of transcutaneous bilirubinometer measurements to identify the hyperbilirubinemia in outpatient newborn population. ( 29601801 )
2018
41
UGT1A1 Genetic Variations and a Haplotype Associated with Neonatal Hyperbilirubinemia in Indonesian Population. ( 29607327 )
2018
42
Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review. ( 29623226 )
2018
43
The influence of massage on neonatal hyperbilirubinemia: a meta-analysis of randomized controlled trials. ( 29631455 )
2018
44
Adherence to hyperbilirubinemia guidelines by midwives, general practitioners, and pediatricians in Indonesia. ( 29672616 )
2018
45
Mutation responsible for congenital photosensitivity and hyperbilirubinemia in Southdown sheep. ( 29688779 )
2018
46
Gadoxetic acid-enhanced magnetic resonance imaging to predict paritaprevir-induced hyperbilirubinemia during treatment of hepatitis C. ( 29709031 )
2018
47
Adoption of the American Academy of Pediatrics' neonatal hyperbilirubinemia guidelines and its effect on blood exchange transfusion rate in a tertiary care center in Amman, Jordan. ( 29713209 )
2018
48
Hyperbilirubinemia following lenalidomide administration. ( 29744077 )
2018
49
Liver Failure and Conjugated Hyperbilirubinemia in a Preterm Neonate: Role of Early IVIG and Exchange Transfusion. ( 29765787 )
2018
50
Correlation between serum vitamin D level and neonatal indirect hyperbilirubinemia. ( 29803223 )
2018

Variations for Bilirubin Metabolic Disorder

ClinVar genetic disease variations for Bilirubin Metabolic Disorder:

6 (show all 34)
# Gene Variation Type Significance SNP ID Assembly Location
1 F12 NM_000505.3(F12): c.983C> G (p.Thr328Arg) single nucleotide variant Pathogenic rs118204456 GRCh37 Chromosome 5, 176831232: 176831232
2 F12 NM_000505.3(F12): c.983C> G (p.Thr328Arg) single nucleotide variant Pathogenic rs118204456 GRCh38 Chromosome 5, 177404231: 177404231
3 UGT1A1 NM_000463.2(UGT1A1): c.1456T> G (p.Tyr486Asp) single nucleotide variant Pathogenic rs34993780 GRCh37 Chromosome 2, 234681059: 234681059
4 UGT1A1 NM_000463.2(UGT1A1): c.1456T> G (p.Tyr486Asp) single nucleotide variant Pathogenic rs34993780 GRCh38 Chromosome 2, 233772413: 233772413
5 UGT1A1 NM_000463.2(UGT1A1): c.141C> A (p.Ile47=) single nucleotide variant Uncertain significance rs34526305 GRCh37 Chromosome 2, 234669074: 234669074
6 UGT1A1 NM_000463.2(UGT1A1): c.141C> A (p.Ile47=) single nucleotide variant Uncertain significance rs34526305 GRCh38 Chromosome 2, 233760428: 233760428
7 UGT1A1 NM_000463.2(UGT1A1): c.141C> T (p.Ile47=) single nucleotide variant Conflicting interpretations of pathogenicity rs34526305 GRCh37 Chromosome 2, 234669074: 234669074
8 UGT1A1 NM_000463.2(UGT1A1): c.141C> T (p.Ile47=) single nucleotide variant Conflicting interpretations of pathogenicity rs34526305 GRCh38 Chromosome 2, 233760428: 233760428
9 UGT1A1 NM_000463.2(UGT1A1): c.322C> T (p.Arg108Cys) single nucleotide variant Uncertain significance rs587784538 GRCh37 Chromosome 2, 234669255: 234669255
10 UGT1A1 NM_000463.2(UGT1A1): c.322C> T (p.Arg108Cys) single nucleotide variant Uncertain significance rs587784538 GRCh38 Chromosome 2, 233760609: 233760609
11 UGT1A1 NM_000463.2(UGT1A1): c.476T> C (p.Ile159Thr) single nucleotide variant Uncertain significance rs587784539 GRCh37 Chromosome 2, 234669409: 234669409
12 UGT1A1 NM_000463.2(UGT1A1): c.476T> C (p.Ile159Thr) single nucleotide variant Uncertain significance rs587784539 GRCh38 Chromosome 2, 233760763: 233760763
13 UGT1A1 NM_000463.2(UGT1A1): c.479T> A (p.Val160Glu) single nucleotide variant Uncertain significance rs587784540 GRCh37 Chromosome 2, 234669412: 234669412
14 UGT1A1 NM_000463.2(UGT1A1): c.479T> A (p.Val160Glu) single nucleotide variant Uncertain significance rs587784540 GRCh38 Chromosome 2, 233760766: 233760766
15 UGT1A1 NM_000463.2(UGT1A1): c.674T> G (p.Val225Gly) single nucleotide variant Conflicting interpretations of pathogenicity rs35003977 GRCh37 Chromosome 2, 234669607: 234669607
16 UGT1A1 NM_000463.2(UGT1A1): c.674T> G (p.Val225Gly) single nucleotide variant Conflicting interpretations of pathogenicity rs35003977 GRCh38 Chromosome 2, 233760961: 233760961
17 UGT1A1 NM_000463.2(UGT1A1): c.748T> C (p.Ser250Pro) single nucleotide variant Uncertain significance rs57307513 GRCh37 Chromosome 2, 234669681: 234669681
18 UGT1A1 NM_000463.2(UGT1A1): c.748T> C (p.Ser250Pro) single nucleotide variant Uncertain significance rs57307513 GRCh38 Chromosome 2, 233761035: 233761035
19 UGT1A1 NM_000463.2(UGT1A1): c.996+15T> C single nucleotide variant Conflicting interpretations of pathogenicity rs4148327 GRCh37 Chromosome 2, 234675826: 234675826
20 UGT1A1 NM_000463.2(UGT1A1): c.996+15T> C single nucleotide variant Conflicting interpretations of pathogenicity rs4148327 GRCh38 Chromosome 2, 233767180: 233767180
21 UGT1A1 NM_000463.2(UGT1A1): c.1084+1G> T single nucleotide variant Pathogenic rs587784535 GRCh37 Chromosome 2, 234676583: 234676583
22 UGT1A1 NM_000463.2(UGT1A1): c.1084+1G> T single nucleotide variant Pathogenic rs587784535 GRCh38 Chromosome 2, 233767937: 233767937
23 UGT1A1 NM_000463.2(UGT1A1): c.1231G> T (p.Val411Leu) single nucleotide variant Uncertain significance rs36076514 GRCh37 Chromosome 2, 234677012: 234677012
24 UGT1A1 NM_000463.2(UGT1A1): c.1231G> T (p.Val411Leu) single nucleotide variant Uncertain significance rs36076514 GRCh38 Chromosome 2, 233768366: 233768366
25 UGT1A1 NM_000463.2(UGT1A1): c.1354G> T (p.Val452Leu) single nucleotide variant Uncertain significance rs587784536 GRCh37 Chromosome 2, 234680957: 234680957
26 UGT1A1 NM_000463.2(UGT1A1): c.1354G> T (p.Val452Leu) single nucleotide variant Uncertain significance rs587784536 GRCh38 Chromosome 2, 233772311: 233772311
27 UGT1A1 NM_000463.2(UGT1A1): c.1413G> A (p.Ala471=) single nucleotide variant Uncertain significance rs587784537 GRCh37 Chromosome 2, 234681016: 234681016
28 UGT1A1 NM_000463.2(UGT1A1): c.1413G> A (p.Ala471=) single nucleotide variant Uncertain significance rs587784537 GRCh38 Chromosome 2, 233772370: 233772370
29 UGT1A1 NM_000463.2(UGT1A1): c.238_239insGTAC (p.Pro80Argfs) insertion Pathogenic rs797046090 GRCh38 Chromosome 2, 233760525: 233760526
30 UGT1A1 NM_000463.2(UGT1A1): c.238_239insGTAC (p.Pro80Argfs) insertion Pathogenic rs797046090 GRCh37 Chromosome 2, 234669171: 234669172
31 UGT1A1 NM_000463.2(UGT1A1): c.722_723delAG (p.Glu241Glyfs) deletion Pathogenic rs797046091 GRCh38 Chromosome 2, 233761009: 233761010
32 UGT1A1 NM_000463.2(UGT1A1): c.722_723delAG (p.Glu241Glyfs) deletion Pathogenic rs797046091 GRCh37 Chromosome 2, 234669655: 234669656
33 UGT1A1 NM_000463.2(UGT1A1): c.1091C> T (p.Pro364Leu) single nucleotide variant Likely pathogenic rs34946978 GRCh38 Chromosome 2, 233768226: 233768226
34 UGT1A1 NM_000463.2(UGT1A1): c.1091C> T (p.Pro364Leu) single nucleotide variant Likely pathogenic rs34946978 GRCh37 Chromosome 2, 234676872: 234676872

Expression for Bilirubin Metabolic Disorder

Search GEO for disease gene expression data for Bilirubin Metabolic Disorder.

Pathways for Bilirubin Metabolic Disorder

Pathways related to Bilirubin Metabolic Disorder according to KEGG:

37
# Name Kegg Source Accession
1 Porphyrin and chlorophyll metabolism hsa00860
2 ABC transporters hsa02010
3 Bile secretion hsa04976

Pathways related to Bilirubin Metabolic Disorder according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1 12.22 ABCC2 G6PD PKM UGT1A1 UGT1A6 UGT1A7
2
Show member pathways
12.13 HMOX1 UGT1A1 UGT1A6 UGT1A7
3
Show member pathways
11.63 ABCC2 SLCO1B1 UGT1A1
4
Show member pathways
11.58 ABCC2 UGT1A1 UGT1A6
6
Show member pathways
11.45 UGT1A1 UGT1A6 UGT1A7
7
Show member pathways
11.43 ABCC2 NR1I3 UGT1A1 UGT1A6
8 11.33 ABCC2 G6PD GGT1 HMOX1 UGT1A1 UGT1A6
9 11.29 UGT1A1 UGT1A6 UGT1A7
10
Show member pathways
11.16 ABCC2 SLCO1B1 UGT1A1
11
Show member pathways
11.09 ABCC2 SLCO1B1 UGT1A1 UGT1A6 UGT1A7
12 10.96 ABCC2 NR1I3 UGT1A1 UGT1A6
13
Show member pathways
10.85 ABCC2 SLCO1B1
14 10.77 ABCC2 NR1I3 SLCO1B1
15 10.74 G6PD GPT

GO Terms for Bilirubin Metabolic Disorder

Cellular components related to Bilirubin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.56 ALB F12 F2 G6PD GGT1 GPT
2 extracellular space GO:0005615 9.28 ADAMTS13 ALB F12 F2 GGT1 GPT

Biological processes related to Bilirubin Metabolic Disorder according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 response to organic substance GO:0010033 9.69 HP PKM UGT1A1
2 hemostasis GO:0007599 9.58 ADAMTS13 F12 F2
3 blood coagulation, intrinsic pathway GO:0007597 9.55 F12 F2
4 zymogen activation GO:0031638 9.54 F12 GGT1
5 retinoic acid metabolic process GO:0042573 9.52 UGT1A1 UGT1A7
6 acute-phase response GO:0006953 9.5 F2 HP UGT1A1
7 positive regulation of blood coagulation GO:0030194 9.49 F12 F2
8 regulation of blood coagulation GO:0030193 9.48 F12 F2
9 thyroid hormone transport GO:0070327 9.46 ABCC2 SLCO1B1
10 heme catabolic process GO:0042167 9.43 HMOX1 UGT1A1
11 response to steroid hormone GO:0048545 9.43 ABCC2 OXT UGT1A1
12 flavone metabolic process GO:0051552 9.37 UGT1A1 UGT1A7
13 cellular glucuronidation GO:0052695 9.33 UGT1A1 UGT1A6 UGT1A7
14 xenobiotic glucuronidation GO:0052697 9.13 UGT1A1 UGT1A6 UGT1A7
15 flavonoid glucuronidation GO:0052696 8.8 UGT1A1 UGT1A6 UGT1A7

Molecular functions related to Bilirubin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring hexosyl groups GO:0016758 9.43 UGT1A1 UGT1A6 UGT1A7
2 glucuronosyltransferase activity GO:0015020 9.33 UGT1A1 UGT1A6 UGT1A7
3 retinoic acid binding GO:0001972 9.13 UGT1A1 UGT1A6 UGT1A7
4 UDP-glycosyltransferase activity GO:0008194 8.8 UGT1A1 UGT1A6 UGT1A7

Sources for Bilirubin Metabolic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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