MCID: BPH002
MIFTS: 29

Biphasic Synovial Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Biphasic Synovial Sarcoma

MalaCards integrated aliases for Biphasic Synovial Sarcoma:

Name: Biphasic Synovial Sarcoma 12 15
Synovial Sarcoma, Biphasic 12 74
Biphasic Sarcoma of Synovium 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5492
NCIt 51 C4279
SNOMED-CT 69 18588008
UMLS 74 C0334507

Summaries for Biphasic Synovial Sarcoma

MalaCards based summary : Biphasic Synovial Sarcoma, also known as synovial sarcoma, biphasic, is related to sarcoma and spindle cell sarcoma. An important gene associated with Biphasic Synovial Sarcoma is CDH1 (Cadherin 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Striated Muscle Contraction. Affiliated tissues include thyroid, small intestine and lung.

Related Diseases for Biphasic Synovial Sarcoma

Diseases related to Biphasic Synovial Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 sarcoma 31.1 EWSR1 SSX1 VIM
2 spindle cell sarcoma 30.4 DES MUC1 VIM
3 papillary carcinoma 30.0 CDH1 MUC1
4 cavernous hemangioma 30.0 DES MUC1 VIM
5 sarcoma, synovial 29.7 CDH1 DES HEATR3 MUC1 SSX1 VIM
6 ewing sarcoma 29.7 CDH1 DES EWSR1 VIM
7 adenoid squamous cell carcinoma 10.3 CDH1 VIM
8 infantile digital fibromatosis 10.2 DES VIM
9 fibromatosis 10.2 DES VIM
10 lymphangiomatosis 10.2 DES VIM
11 angiolipoma 10.2 DES VIM
12 primitive neuroectodermal tumor of the cervix uteri 10.2 DES VIM
13 leiomyosarcoma 10.2 DES VIM
14 spindle cell lipoma 10.2 DES VIM
15 epulis 10.2 DES VIM
16 epithelioid leiomyosarcoma 10.2 DES VIM
17 benign metastasizing leiomyoma 10.2 DES VIM
18 leiomyoma 10.2 DES VIM
19 cystic nephroma 10.2 DES VIM
20 juvenile xanthogranuloma 10.2 DES VIM
21 cutaneous fibrous histiocytoma 10.2 DES VIM
22 congenital fibrosarcoma 10.2 DES VIM
23 pseudosarcomatous fibromatosis 10.2 DES VIM
24 sarcomatoid renal cell carcinoma 10.2 CDH1 MUC1
25 malignant peritoneal mesothelioma 10.2 MUC1 VIM
26 papillary tumor of the pineal region 10.2 MUC1 VIM
27 glomus tumor 10.2 DES VIM
28 secretory meningioma 10.2 MUC1 VIM
29 granular cell tumor 10.2 DES VIM
30 fibrous meningioma 10.2 MUC1 VIM
31 chordoid meningioma 10.2 MUC1 VIM
32 nodular hidradenoma 10.2 MUC1 VIM
33 hidradenoma 10.2 MUC1 VIM
34 clear cell ependymoma 10.2 MUC1 VIM
35 ependymoma 10.2 MUC1 VIM
36 eccrine porocarcinoma 10.2 MUC1 VIM
37 lobular neoplasia 10.2 CDH1 MUC1
38 embryonal sarcoma 10.2 DES VIM
39 smooth muscle tumor 10.2 DES VIM
40 lymphoepithelioma-like carcinoma 10.2 CDH1 MUC1
41 endometrial mucinous adenocarcinoma 10.2 MUC1 VIM
42 adenofibroma 10.2 MUC1 VIM
43 congenital epulis 10.2 DES VIM
44 clear cell meningioma 10.2 MUC1 VIM
45 myxopapillary ependymoma 10.2 MUC1 VIM
46 infantile myofibromatosis 10.2 DES VIM
47 gastric cardia carcinoma 10.2 CDH1 MUC1
48 cutaneous leiomyosarcoma 10.2 DES MUC1
49 spindle cell thymoma 10.2 DES MUC1
50 anaplastic ependymoma 10.2 MUC1 VIM

Graphical network of the top 20 diseases related to Biphasic Synovial Sarcoma:



Diseases related to Biphasic Synovial Sarcoma

Symptoms & Phenotypes for Biphasic Synovial Sarcoma

Drugs & Therapeutics for Biphasic Synovial Sarcoma

Search Clinical Trials , NIH Clinical Center for Biphasic Synovial Sarcoma

Genetic Tests for Biphasic Synovial Sarcoma

Anatomical Context for Biphasic Synovial Sarcoma

MalaCards organs/tissues related to Biphasic Synovial Sarcoma:

42
Thyroid, Small Intestine, Lung, Ovary, Cervix, Smooth Muscle, Pineal

Publications for Biphasic Synovial Sarcoma

Articles related to Biphasic Synovial Sarcoma:

(show top 50) (show all 52)
# Title Authors Year
1
Primary biphasic synovial sarcoma of the right atrium. ( 26178188 )
2018
2
Biphasic synovial sarcoma of the epiglottis: Case report and literature review. ( 28689931 )
2018
3
Laser capture microdissection for detecting the expression of epithelial-mesenchymal transition-related genes in epithelial and spindle cells of paraffin-embedded formalin-fixed biphasic synovial sarcoma. ( 29575169 )
2018
4
Primary thyroid biphasic synovial sarcoma and synchronous papillary carcinoma: report of a remarkable case. ( 30546147 )
2018
5
Biphasic synovial sarcoma with prominent cavernous hemangioma-like stroma. ( 27988941 )
2017
6
PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors. ( 28248726 )
2017
7
Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component: Report of a case. ( 27118264 )
2016
8
Intravascular Biphasic Synovial Sarcoma: The Beneficial Role of Adjuvant Treatment Approach in the Pre-metastatic Stage. ( 27190730 )
2016
9
Biphasic synovial sarcoma in a 19-year-old pregnant woman: a case report. ( 25826519 )
2015
10
Biphasic synovial sarcoma of the hypopharynx. ( 25923284 )
2015
11
Superficial soft tissue biphasic synovial sarcoma with apocrine differentiation in the glandular component: a report of two cases. ( 23563252 )
2014
12
SS18-bronchial biphasic synovial sarcoma in an octogenarian with hemothorax. ( 24429587 )
2014
13
A non-joint tissue biphasic synovial sarcoma in a dog. ( 24447570 )
2014
14
Primary biphasic synovial sarcoma of gingiva: Report of a rare case. ( 24959041 )
2014
15
Biphasic synovial sarcoma arising from superior vena cava. ( 22419995 )
2012
16
Primary pulmonary biphasic synovial sarcoma: a case report and literature review. ( 22472156 )
2012
17
Primary intrathoracic biphasic synovial sarcoma. ( 22519387 )
2012
18
Pericardium: an exceedingly rare site for a primary biphasic synovial sarcoma. ( 22771650 )
2012
19
Biphasic synovial sarcoma of the extremity: quadruple approach of isolated limb perfusion, surgical ablation, adipofascial perforator flap and radiation to avoid amputation. ( 21516237 )
2011
20
Biphasic synovial sarcoma in the cervical spine: Case report. ( 21605432 )
2011
21
Biphasic synovial sarcoma in mandibular region. ( 22529590 )
2011
22
Cryptic SYT/SXX1 fusion gene in high-grade biphasic synovial sarcoma with unique complex rearrangement and extensive BCL2 overexpression. ( 20082858 )
2010
23
Cytogenetic heterogeneity in biphasic synovial sarcoma associated with telomere instability. ( 20113844 )
2010
24
Primary pulmonary biphasic synovial sarcoma confirmed by molecular detection of a SYT-SSX2 fusion gene: report of 1 case. ( 20830232 )
2010
25
Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature. ( 21358103 )
2010
26
Biphasic synovial sarcoma. ( 18761552 )
2009
27
Biphasic synovial sarcoma of oral cavity. ( 18983797 )
2008
28
Biphasic synovial sarcoma of the abdominal wall. ( 16855839 )
2006
29
Biphasic synovial sarcoma of the posterior pharyngeal wall: a case report. ( 15971754 )
2005
30
Primary intrathoracic biphasic synovial sarcoma--a case report. ( 16477881 )
2005
31
Establishment and characterization of a biphasic synovial sarcoma cell line, SYO-1. ( 14744540 )
2004
32
Canine biphasic synovial sarcoma: case report and immunohistochemical characterization. ( 15192346 )
2004
33
Well-differentiated biphasic synovial sarcoma in the atlanto-occipital joint of a Holstein cow. ( 15557078 )
2004
34
MAGE antigen expression in monophasic and biphasic synovial sarcoma. ( 11957149 )
2002
35
Differential Ki67 and bcl-2 immunoexpression in solid-glandular and spindle cell components of biphasic synovial sarcoma: a double immunostaining assessment with cytokeratin and vimentin. ( 12010367 )
2002
36
Biphasic synovial sarcoma in a 13-month-old girl. ( 12151720 )
2002
37
Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection. ( 11561755 )
2001
38
Detection of SYT-SSX fusion transcripts in both epithelial and spindle cell areas of biphasic synovial sarcoma using laser capture microdissection. ( 10889911 )
2000
39
Pathologic quiz case. Pulmonary mass in a patient presenting with a hemothorax. Diagnosis: primary pulmonary biphasic synovial sarcoma. ( 10583938 )
1999
40
Translocation (X;18) in a biphasic synovial sarcoma with morphologic features of neural differentiation. ( 9646030 )
1998
41
Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR. ( 9739025 )
1998
42
Primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma: a case report. ( 9539323 )
1998
43
Biphasic synovial sarcoma of the peritoneal cavity with t(X;18) demonstrated by reverse transcriptase polymerase chain reaction. ( 9311017 )
1997
44
Primary biphasic synovial sarcoma of the pleura. ( 9415360 )
1997
45
Intraneural biphasic synovial sarcoma: an alternative "glandular" tumor of peripheral nerve. ( 8832556 )
1996
46
Biphasic synovial sarcoma in the small intestinal mesentery. ( 7539716 )
1995
47
Primary biphasic synovial sarcoma of the orbit. ( 1313455 )
1992
48
Fine needle aspiration cytology of biphasic synovial sarcoma of soft tissue. Report of a case with ultrastructural, immunohistologic and cytophotometric studies. ( 2296842 )
1990
49
Neuroendocrine differentiation in the glandular peripheral nerve sheath tumor. Pathologic distinction from the biphasic synovial sarcoma with glands. ( 2837100 )
1988
50
Pathologic quiz case 2. Synovial sarcoma (biphasic). ( 2838054 )
1988

Variations for Biphasic Synovial Sarcoma

Expression for Biphasic Synovial Sarcoma

Search GEO for disease gene expression data for Biphasic Synovial Sarcoma.

Pathways for Biphasic Synovial Sarcoma

Pathways related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 CDH1 DES MUC1 VIM
2 11.11 DES VIM
3
Show member pathways
10.81 DES VIM
4 10.21 CDH1 VIM

GO Terms for Biphasic Synovial Sarcoma

Biological processes related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 DES VIM
2 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 CDH1 DES EWSR1 VIM

Sources for Biphasic Synovial Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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