MCID: BPH002
MIFTS: 28

Biphasic Synovial Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Biphasic Synovial Sarcoma

MalaCards integrated aliases for Biphasic Synovial Sarcoma:

Name: Biphasic Synovial Sarcoma 12 15
Synovial Sarcoma, Biphasic 12 72
Biphasic Sarcoma of Synovium 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5492
NCIt 50 C4279
SNOMED-CT 68 18588008
UMLS 72 C0334507

Summaries for Biphasic Synovial Sarcoma

MalaCards based summary : Biphasic Synovial Sarcoma, also known as synovial sarcoma, biphasic, is related to spindle cell sarcoma and sarcoma. An important gene associated with Biphasic Synovial Sarcoma is SSX1 (SSX Family Member 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Striated Muscle Contraction. Affiliated tissues include bone, heart and lung.

Related Diseases for Biphasic Synovial Sarcoma

Diseases related to Biphasic Synovial Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 spindle cell sarcoma 31.3 VIM MUC1 DES
2 sarcoma 30.6 VIM SSX1 EWSR1
3 cavernous hemangioma 30.1 VIM MUC1 DES
4 monophasic synovial sarcoma 29.9 VIM SSX1 MUC1
5 papillary carcinoma 29.7 MUC1 CDH1
6 sarcoma, synovial 29.4 VIM SSX1 MUC1 HEATR3 DES CDH1
7 ewing sarcoma 29.1 VIM EWSR1 DES CDH1
8 cutaneous leiomyosarcoma 10.5 MUC1 DES
9 spindle cell thymoma 10.5 MUC1 DES
10 sarcomatoid renal cell carcinoma 10.5 MUC1 CDH1
11 spindle cell rhabdomyosarcoma 10.4 MUC1 DES
12 adenoid squamous cell carcinoma 10.4 VIM CDH1
13 infantile digital fibromatosis 10.4 VIM DES
14 lymphoepithelioma-like carcinoma 10.4 MUC1 CDH1
15 fibromatosis 10.4 VIM DES
16 lymphangiomatosis 10.4 VIM DES
17 primitive neuroectodermal tumor of the cervix uteri 10.4 VIM DES
18 angiolipoma 10.4 VIM DES
19 lobular neoplasia 10.4 MUC1 CDH1
20 leiomyosarcoma 10.4 VIM DES
21 proximal spinal muscular atrophy 10.4 MUC1 DES
22 ischemic fasciitis 10.4 MUC1 DES
23 fasciitis 10.4 MUC1 DES
24 epulis 10.4 VIM DES
25 spindle cell lipoma 10.4 VIM DES
26 gastric cardia carcinoma 10.4 MUC1 CDH1
27 epithelioid leiomyosarcoma 10.4 VIM DES
28 plasmablastic lymphoma 10.4 MUC1 DES
29 benign metastasizing leiomyoma 10.4 VIM DES
30 malignant peritoneal mesothelioma 10.4 VIM MUC1
31 papillary tumor of the pineal region 10.4 VIM MUC1
32 cystic nephroma 10.4 VIM DES
33 secretory meningioma 10.4 VIM MUC1
34 juvenile xanthogranuloma 10.4 VIM DES
35 tubular adenocarcinoma 10.4 MUC1 CDH1
36 chordoid meningioma 10.4 VIM MUC1
37 signet ring cell adenocarcinoma 10.4 MUC1 CDH1
38 fibrous meningioma 10.4 VIM MUC1
39 congenital fibrosarcoma 10.4 VIM DES
40 eccrine porocarcinoma 10.4 VIM MUC1
41 rare tumor 10.4
42 cutaneous fibrous histiocytoma 10.4 VIM DES
43 clear cell ependymoma 10.4 VIM MUC1
44 ependymoma 10.4 VIM MUC1
45 nodular hidradenoma 10.4 VIM MUC1
46 hidradenoma 10.4 VIM MUC1
47 endometrial mucinous adenocarcinoma 10.4 VIM MUC1
48 bile duct adenocarcinoma 10.4 MUC1 CDH1
49 pseudosarcomatous fibromatosis 10.4 VIM DES
50 myxopapillary ependymoma 10.4 VIM MUC1

Graphical network of the top 20 diseases related to Biphasic Synovial Sarcoma:



Diseases related to Biphasic Synovial Sarcoma

Symptoms & Phenotypes for Biphasic Synovial Sarcoma

Drugs & Therapeutics for Biphasic Synovial Sarcoma

Search Clinical Trials , NIH Clinical Center for Biphasic Synovial Sarcoma

Genetic Tests for Biphasic Synovial Sarcoma

Anatomical Context for Biphasic Synovial Sarcoma

MalaCards organs/tissues related to Biphasic Synovial Sarcoma:

41
Bone, Heart, Lung, Thyroid, Colon, Kidney, Small Intestine

Publications for Biphasic Synovial Sarcoma

Articles related to Biphasic Synovial Sarcoma:

(show top 50) (show all 142)
# Title Authors PMID Year
1
PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors. 38
28248726 2019
2
From fine-needle aspiration cytology to fluorescent in-situ hybridization in an unusual case of pharyngeal synovial sarcoma. 38
31293093 2019
3
Primary synovial sarcoma of the ovary and Fallopian tube - case report and review of the literature. 38
31324112 2019
4
Primary thyroid biphasic synovial sarcoma and synchronous papillary carcinoma: report of a remarkable case. 38
30546147 2018
5
Laser capture microdissection for detecting the expression of epithelial-mesenchymal transition-related genes in epithelial and spindle cells of paraffin-embedded formalin-fixed biphasic synovial sarcoma. 38
29575169 2018
6
Biphasic synovial sarcoma of the epiglottis: Case report and literature review. 38
28689931 2018
7
Synovial sarcoma of the transverse colon: a rare cause of intussusception. 38
29602893 2018
8
Primary biphasic synovial sarcoma of the right atrium. 38
26178188 2018
9
PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy. 38
30524904 2018
10
Gastroblastoma harbors a recurrent somatic MALAT1-GLI1 fusion gene. 38
28731043 2017
11
Biphasic synovial sarcoma with prominent cavernous hemangioma-like stroma. 38
27988941 2017
12
Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas. 38
28084340 2017
13
Transoral robotic surgery for the pediatric head and neck surgeries. 38
28004263 2017
14
Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component: Report of a case. 38
27118264 2016
15
Intravascular Biphasic Synovial Sarcoma: The Beneficial Role of Adjuvant Treatment Approach in the Pre-metastatic Stage. 38
27190730 2016
16
Primary mediastinal synovial sarcoma: A rare case report. 38
27621098 2016
17
Primary synovial sarcoma of the right heart involving the tricuspid valve in an elderly Chinese woman: a case report. 38
26112006 2015
18
Biphasic synovial sarcoma of the hypopharynx. 38
25923284 2015
19
Biphasic synovial sarcoma in a 19-year-old pregnant woman: a case report. 38
25826519 2015
20
Superficial soft tissue biphasic synovial sarcoma with apocrine differentiation in the glandular component: a report of two cases. 38
23563252 2014
21
Epidemiology and survivorship of soft tissue sarcomas in adults: a national cancer database report. 38
25044961 2014
22
Primary peripheral neurolymphomatosis mimicking synovial sarcoma: FDG PETCT to the rescue. 38
25313768 2014
23
SS18-bronchial biphasic synovial sarcoma in an octogenarian with hemothorax. 38
24429587 2014
24
A non-joint tissue biphasic synovial sarcoma in a dog. 38
24447570 2014
25
Primary biphasic synovial sarcoma of gingiva: Report of a rare case. 38
24959041 2014
26
Primary intra-abdominal synovial sarcoma: a case report. 38
24556573 2013
27
Pediatric primitive intraneural synovial sarcoma of L-5 nerve root. 38
23414131 2013
28
Primary intra-abdominal synovial sarcoma: a case report. 38
24505604 2013
29
Laryngeal synovial sarcoma: a rare clinical entity. 38
23984145 2013
30
MUC4 is a sensitive and extremely useful marker for sclerosing epithelioid fibrosarcoma: association with FUS gene rearrangement. 38
22982887 2012
31
Biphasic synovial sarcoma arising from superior vena cava. 38
22419995 2012
32
Primary intrathoracic biphasic synovial sarcoma. 38
22519387 2012
33
Vascular endothelial growth factor receptor 2 as a marker for malignant vascular tumors and mesothelioma: an immunohistochemical study of 262 vascular endothelial and 1640 nonvascular tumors. 38
22314185 2012
34
Pericardium: an exceedingly rare site for a primary biphasic synovial sarcoma. 38
22771650 2012
35
Primary pulmonary biphasic synovial sarcoma: a case report and literature review. 38
22472156 2012
36
Synovial sarcoma involving the median nerve: a case report. 38
23011830 2012
37
Claudin-5 as an immunohistochemical marker for angiosarcoma and hemangioendotheliomas. 38
21959309 2011
38
Biphasic synovial sarcoma in the cervical spine: Case report. 38
21605432 2011
39
Biphasic synovial sarcoma in mandibular region. 38
22529590 2011
40
Biphasic synovial sarcoma of the extremity: quadruple approach of isolated limb perfusion, surgical ablation, adipofascial perforator flap and radiation to avoid amputation. 38
21516237 2011
41
Primary synovial sarcoma of the mediastinum : a case report. 38
22606585 2011
42
Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature. 38
21358103 2010
43
Primary pulmonary biphasic synovial sarcoma confirmed by molecular detection of a SYT-SSX2 fusion gene: report of 1 case. 38
20830232 2010
44
[Primary biphasic synovial sarcoma of the kidney]. 38
20094701 2010
45
Cytogenetic heterogeneity in biphasic synovial sarcoma associated with telomere instability. 38
20113844 2010
46
Synovial Sarcoma: A Clinicopathological and Radiological Study of 12 Cases Seen Over 18 Years. 38
29147174 2010
47
Cryptic SYT/SXX1 fusion gene in high-grade biphasic synovial sarcoma with unique complex rearrangement and extensive BCL2 overexpression. 38
20082858 2010
48
A distinctive novel epitheliomesenchymal biphasic tumor of the stomach in young adults ("gastroblastoma"): a series of 3 cases. 38
19718790 2009
49
The classic prognostic factors tumor stage, tumor size, and tumor grade are the strongest predictors of outcome in synovial sarcoma: no role for SSX fusion type or ezrin expression. 38
18997619 2009
50
Biphasic synovial sarcoma. 38
18761552 2009

Variations for Biphasic Synovial Sarcoma

Expression for Biphasic Synovial Sarcoma

Search GEO for disease gene expression data for Biphasic Synovial Sarcoma.

Pathways for Biphasic Synovial Sarcoma

Pathways related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 VIM MUC1 DES CDH1
2 11.11 VIM DES
3
Show member pathways
10.81 VIM DES
4 10.21 VIM CDH1

GO Terms for Biphasic Synovial Sarcoma

Biological processes related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 9.16 VIM DES
2 positive regulation of collagen biosynthetic process GO:0032967 8.96 VIM CREB3L1
3 intermediate filament organization GO:0045109 8.62 VIM DES

Molecular functions related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 VIM EWSR1 DES CDH1

Sources for Biphasic Synovial Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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