Aliases & Classifications for Bird Fancier's Lung

MalaCards integrated aliases for Bird Fancier's Lung:

Name: Bird Fancier's Lung 12 45 15 17 74
Pigeon Breeder's Lung 12 74
Avian Hypersensitivity Pneumonitis 12
Poultry Worker's Lung 12
Bird Breeder's Lung 12
Bird-Fancier's Lung 12
Bird-Fanciers' Lung 12
Bird Fancier Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13891
ICD9CM 36 495.2
MeSH 45 D001716
NCIt 51 C34425
SNOMED-CT 69 69339004
ICD10 34 J67.2

Summaries for Bird Fancier's Lung

Disease Ontology : 12 An extrinsic allergic alveolitis which is caused by inhalation of antigens from avian excreta. The disease has symptom abrupt onset of dyspnea, has symptom cough, has symptom malaise, and has symptom fever, after exposure to antigen.

MalaCards based summary : Bird Fancier's Lung, also known as pigeon breeder's lung, is related to ventilation pneumonitis and lung disease, and has symptoms including fever, cough and malaise. An important gene associated with Bird Fancier's Lung is SYNE1 (Spectrin Repeat Containing Nuclear Envelope Protein 1), and among its related pathways/superpathways are ERK Signaling and PEDF Induced Signaling. The drug Lidocaine has been mentioned in the context of this disorder. Affiliated tissues include lung, testes and t cells, and related phenotypes are no effect and hematopoietic system

Wikipedia : 77 Bird fancier''s lung (BFL) is a type of hypersensitivity pneumonitis (HP). It is triggered by exposure... more...

Related Diseases for Bird Fancier's Lung

Diseases related to Bird Fancier's Lung via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 ventilation pneumonitis 30.8 CD4 IGLL1
2 lung disease 29.7 CXCL10 CXCR3 ELANE SFTPD
3 hypersensitivity pneumonitis, familial 11.5
4 pulmonary fibrosis 10.5
5 pleuroparenchymal fibroelastosis 10.4 MUC1 SFTPD
6 pneumonia 10.3
7 extrinsic allergic alveolitis 10.3
8 metal allergy 10.3 CD4 CD8A
9 acute interstitial pneumonia 10.3 MUC1 SFTPD
10 polyclonal hypergammaglobulinemia 10.2 CD4 CD8A
11 pneumocystosis 10.2 CD4 MUC1 SFTPD
12 type 1 diabetes mellitus 18 10.2 TNFRSF10A TNFRSF25
13 farmer's lung 10.2
14 nocardiosis 10.2
15 idiopathic interstitial pneumonia 10.2
16 paragonimiasis 10.2 CCL17 CXCR3
17 cryptogenic organizing pneumonia 10.1 CD8A MUC1
18 diffuse scleroderma 10.1 TNFRSF10B TNFRSF25
19 interstitial lung disease 10.1 CCL17 MUC1 SFTPD
20 acute respiratory distress syndrome 10.0 ELANE LTA SFTPD
21 aspergillosis 10.0 CCL17 ELANE SFTPD
22 opsoclonus-myoclonus syndrome 10.0 CXCL10 CXCR3
23 melkersson-rosenthal syndrome 9.9 ACE CD4 CD8A
24 mycosis fungoides 9.8 CCL17 CXCL10 CXCR3
25 respiratory system disease 9.8 CXCL10 ELANE SFTPD
26 pulmonary sarcoidosis 9.8 ACE CXCR3 SFTPD
27 apple allergy 9.7 CCL17 CXCL10
28 respiratory failure 9.7 ACE ELANE SFTPD
29 pulmonary disease, chronic obstructive 9.7 CXCL10 CXCR3 ELANE SFTPD
30 sarcoidosis 1 9.6 ACE CCL17 CXCR3 LTA
31 human immunodeficiency virus type 1 9.6 CD4 CXCL10 LTA SMAD3
32 pulmonary fibrosis, idiopathic 9.1 CCL17 CXCL10 CXCR3 ELANE MUC1 SFTPD

Graphical network of the top 20 diseases related to Bird Fancier's Lung:



Diseases related to Bird Fancier's Lung

Symptoms & Phenotypes for Bird Fancier's Lung

Symptoms:

12
  • fever
  • cough
  • malaise
  • abrupt onset of dyspnea

GenomeRNAi Phenotypes related to Bird Fancier's Lung according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 9.92 ACE CCL17 CD4 CD8A CXCL10 CXCR3

MGI Mouse Phenotypes related to Bird Fancier's Lung:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.03 ACE CCL17 CD4 CD8A CXCL10 CXCR3
2 homeostasis/metabolism MP:0005376 9.93 ACE CD4 CXCL10 CXCR3 ELANE LTA
3 immune system MP:0005387 9.77 ACE CCL17 CD4 CD8A CXCL10 CXCR3
4 mortality/aging MP:0010768 9.44 ACE CD4 CD8A CXCL10 CXCR3 ELANE

Drugs & Therapeutics for Bird Fancier's Lung

Drugs for Bird Fancier's Lung (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved 137-58-6 3676

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Research for Specific Proteins of Interest for the Serological Diagnosis of Bird Fancier's Lung Recruiting NCT03056404 Not Applicable
2 BPF Genetics of ILD Study Recruiting NCT03747627
3 Immune Response in Hypersensitivity Pneumonitis Recruiting NCT03873649

Search NIH Clinical Center for Bird Fancier's Lung

Cochrane evidence based reviews: bird fancier's lung

Genetic Tests for Bird Fancier's Lung

Anatomical Context for Bird Fancier's Lung

MalaCards organs/tissues related to Bird Fancier's Lung:

42
Lung, Testes, T Cells

Publications for Bird Fancier's Lung

Articles related to Bird Fancier's Lung:

(show top 50) (show all 75)
# Title Authors Year
1
Exacerbation of Previously Undiagnosed Bird Fancier's Lung by Pembrolizumab Therapy. ( 30955583 )
2019
2
Common Proteins Located in Pigeon, Budgerigar, and Hen Droppings Related to Bird Fancier's Lung. ( 29939134 )
2018
3
A Rare Pediatric Case of Severe Bird Fancier's Lung Presented with Viral Pneumonitis-Like Picture. ( 30424525 )
2018
4
Associations of Pulmonary Fibrosis with Peripheral Blood Th1/Th2 Cell Imbalance and EBF3 Gene Methylation in Uygur Pigeon Breeder's Lung Patients. ( 29913442 )
2018
5
Usefulness of à la carte antigens for bird fancier's lung serodiagnosis: total dropping extract and/or dropping's microflora antigens. ( 28901909 )
2017
6
Significance of Foxp3+CD4+ regulatory T cells in the peripheral blood of Uygur patients in the acute and chronic phases of pigeon breeder's lung. ( 27448583 )
2017
7
The correlation between pulmonary fibrosis and methylation of peripheral Smad3 in cases of pigeon breeder's lung in a Chinese Uygur population. ( 28562330 )
2017
8
An immunoproteomic approach revealed antigenic proteins enhancing serodiagnosis performance of bird fancier's lung. ( 28760669 )
2017
9
Correlation of macrophage inflammatory protein-1α single gene polymorphisms with the susceptibility to pigeon breeder's lung in chinese uygur population. ( 26550319 )
2015
10
Bird fancier's lung--comment on: Kumar R., Singh M. "Bird fancier's lung: clinical-radiological presentation in 15 cases". ( 26050986 )
2015
11
Bird fancier's lung: clinical-radiological presentation in 15 cases. ( 25577532 )
2015
12
Immunogenic proteins specific to different bird species in bird fancier's lung. ( 24786679 )
2014
13
Bird fancier's lung caused by diamond dove. ( 23880614 )
2013
14
Bird fancier's lung complicated by pulmonary nocardiosis. ( 23503493 )
2013
15
Bird fancier's lung: a state-of-the-art review. ( 21870048 )
2012
16
Bird fancier's lung which developed in a pigeon breeder presenting organizing pneumonia. ( 21139300 )
2010
17
Bird fancier's lung: a series of 86 patients. ( 18344808 )
2008
18
Effect of cigarette smoking on the development of murine chronic pigeon breeder's lung. The difference between a short-term and a long-term exposure. ( 19845140 )
2007
19
Avian circoviruses of the genus Circovirus: A potential trigger in Pigeon breeder's lung (PBL)/Bird fancier's lung (BFL). ( 16997499 )
2007
20
Pigeon breeder's lung in childhood: is family screening necessary? ( 16400661 )
2006
21
Rosella parrot exposure as a cause of bird fancier's lung. ( 17214289 )
2005
22
Chronic bird fancier's lung: histopathological and clinical correlation. An application of the 2002 ATS/ERS consensus classification of the idiopathic interstitial pneumonias. ( 16061708 )
2005
23
Analysis of KL-6 and SP-D as disease markers in bird fancier's lung. ( 15881280 )
2005
24
Chronic bird fancier's lung presenting with acute exacerbation due to use of a feather duvet. ( 15497520 )
2004
25
Clinical features of recurrent and insidious chronic bird fancier's lung. ( 12839317 )
2003
26
Fatal outcome in chronic bird fancier's lung. ( 12015257 )
2002
27
A hazard of Christmas: Bird Fancier's Lung and the Christmas tree. ( 10714426 )
2000
28
Pigeon breeder's lung in childhood: varied clinical picture at presentation. ( 10922137 )
2000
29
Inhalation provocation tests in chronic bird fancier's lung. ( 11083690 )
2000
30
Sequential changes in bronchoalveolar lavage cells and cytokines in a patient progressing from acute to chronic bird Fancier's lung disease. ( 10563753 )
1999
31
A follow-up study of pulmonary function tests, bronchoalveolar lavage cells, and humoral and cellular immunity in bird fancier's lung. ( 7622754 )
1995
32
Chirping rales in bird-fancier's lung. ( 8325110 )
1993
33
Mortality in Mexican patients with chronic pigeon breeder's lung compared with those with usual interstitial pneumonia. ( 8317813 )
1993
34
Pigeon-breeder's lung. Extensive workup clarifies the clinical picture. ( 8446537 )
1993
35
Exponential analysis of the lung pressure-volume curve in patients with chronic pigeon-breeder's lung. ( 1582296 )
1992
36
Difference in the phenotypes of bronchoalveolar lavage lymphocytes in patients with summer-type hypersensitivity pneumonitis, farmer's lung, ventilation pneumonitis, and bird fancier's lung: report of a nationwide epidemiologic study in Japan. ( 1902851 )
1991
37
Clinical and serologic follow-up of four children and five adults with bird-fancier's lung. ( 2107243 )
1990
38
Confusing serological abnormalities in bird fancier's lung. ( 2264852 )
1990
39
Serological abnormalities in bird fancier's lung. ( 2393746 )
1990
40
Bird-fancier's lung: a case report of probable extrinsic allergic alveolitis in a pigeon-breeder. ( 2635406 )
1989
41
Impaired non-specific delayed cutaneous hypersensitivity in bird fancier's lung. ( 2928997 )
1989
42
Increase of HLA-DR7 in pigeon breeder's lung in a Mexican population. ( 3496181 )
1987
43
Bird Fancier's lung. ( 3733396 )
1986
44
Bird fancier's lung after an unusual exposure to avian protein. ( 3789530 )
1986
45
Bird fancier's lung: hazard of the fishing industry. ( 3936576 )
1985
46
'Atypical pneumonia' due to parakeet sensitivity: bird fancier's lung in a 10-year-old girl. ( 6487532 )
1984
47
Pigeon breeder's lung: association with HLA-DR 3. ( 6408759 )
1983
48
Chronic airflow obstruction in a patient with pigeon breeder's lung: prevalence of IgE antibodies to avian antigens. ( 7100661 )
1982
49
Bird fancier's lung: studies of broncho-alveolar lavage and correlations with inhalation provocation tests. ( 7218859 )
1981
50
Effect of corticosteroid on lymphocyte responsiveness in pigeon breeder's lung. ( 7438415 )
1980

Variations for Bird Fancier's Lung

Expression for Bird Fancier's Lung

Search GEO for disease gene expression data for Bird Fancier's Lung.

Pathways for Bird Fancier's Lung

Pathways related to Bird Fancier's Lung according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.57 CCL17 CD4 CXCL10 CXCR3 LTA MUC1
2
Show member pathways
13.36 CCL17 CD4 CXCL10 CXCR3 LTA SMAD3
3
Show member pathways
13.07 CCL17 CD4 CXCL10 CXCR3 LTA TNFRSF10A
4
Show member pathways
12.59 CCL17 CD4 CXCL10 CXCR3 SMAD3
5
Show member pathways
12.34 CCL17 CD4 CXCL10 CXCR3 LTA SMAD3
6 12.29 CD8A CXCL10 TNFRSF10B TNFRSF25
7
Show member pathways
11.78 CD4 LTA SMAD3
8
Show member pathways
11.7 CCL17 CXCL10 CXCR3
9
Show member pathways
11.45 CCL17 CD4 SMAD3 TNFRSF10A TNFRSF10B TNFRSF25
10 11.36 CD4 CD8A CXCR3 LTA
11 11 CD4 CD8A IGLL1

GO Terms for Bird Fancier's Lung

Cellular components related to Bird Fancier's Lung according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ACE CCL17 CXCL10 ELANE LTA MUC1
2 cell surface GO:0009986 9.72 CD4 CXCR3 ELANE TNFRSF10A TNFRSF10B
3 extracellular region GO:0005576 9.7 ACE CCL17 CD8A CXCL10 ELANE IGLL1
4 T cell receptor complex GO:0042101 9.26 CD4 CD8A
5 external side of plasma membrane GO:0009897 9.1 ACE CD4 CD8A CXCL10 CXCR3 IGLL1

Biological processes related to Bird Fancier's Lung according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.62 ELANE IGLL1 TNFRSF10A TNFRSF10B
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.61 SMAD3 TNFRSF10A TNFRSF10B
3 immune response GO:0006955 9.56 CCL17 CD4 CD8A CXCL10 CXCR3 IGLL1
4 chemokine-mediated signaling pathway GO:0070098 9.54 CCL17 CXCL10 CXCR3
5 response to vitamin D GO:0033280 9.51 CD4 CXCL10
6 activation of NF-kappaB-inducing kinase activity GO:0007250 9.49 TNFRSF10A TNFRSF10B
7 regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 9.48 TNFRSF10A TNFRSF10B
8 negative regulation of growth of symbiont in host GO:0044130 9.46 ELANE LTA
9 T cell activation GO:0042110 9.43 CD4 CD8A SMAD3
10 T cell chemotaxis GO:0010818 9.4 CXCL10 CXCR3
11 cell surface receptor signaling pathway GO:0007166 9.17 CD4 CD8A CXCL10 CXCR3 TNFRSF10A TNFRSF10B
12 TRAIL-activated apoptotic signaling pathway GO:0036462 9.16 TNFRSF10A TNFRSF10B

Molecular functions related to Bird Fancier's Lung according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor activity GO:0038023 9.26 CD4 TNFRSF10A TNFRSF10B TNFRSF25
2 TRAIL binding GO:0045569 8.62 TNFRSF10A TNFRSF10B

Sources for Bird Fancier's Lung

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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