MCID: BZR001
MIFTS: 25

Bizarre Leiomyoma

Categories: Cancer diseases

Aliases & Classifications for Bizarre Leiomyoma

MalaCards integrated aliases for Bizarre Leiomyoma:

Name: Bizarre Leiomyoma 12 15 74
Pleomorphic Leiomyoma 12
Symplastic Leiomyoma 12
Atypical Leiomyoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5127
NCIt 51 C4257
SNOMED-CT 69 48897006
UMLS 74 C0334478

Summaries for Bizarre Leiomyoma

Disease Ontology : 12 A leiomyoma that is characterized by large, atypical nuclei in otherwise normal appearing leiomyoma and rare or absent mitotic figures.

MalaCards based summary : Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to leiomyoma and smooth muscle tumor. An important gene associated with Bizarre Leiomyoma is PGR (Progesterone Receptor), and among its related pathways/superpathways is Senescence and Autophagy in Cancer. Affiliated tissues include breast, smooth muscle and prostate, and related phenotypes are cardiovascular system and mortality/aging

Related Diseases for Bizarre Leiomyoma

Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 65, show less)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 30.7 ACTC1 MED12 PGR
2 smooth muscle tumor 30.2 ACTC1 PGR
3 leiomyosarcoma 30.0 ACTC1 MED12 PGR
4 carcinosarcoma 29.7 ACTC1 PGR
5 uterine corpus bizarre leiomyoma 12.4
6 leiomyoma cutis 10.3
7 lymphangiomatosis 10.2 PCNA PGR
8 benign meningioma 10.2 PCNA PGR
9 calcifying aponeurotic fibroma 10.2 ACTC1 PGR
10 myxoid leiomyosarcoma 10.2 ACTC1 PGR
11 benign metastasizing leiomyoma 10.2 ACTC1 PGR
12 perivascular epithelioid cell tumor 10.1 ACTC1 PGR
13 pseudo-meigs syndrome 10.1
14 meningioma, radiation-induced 10.1 PCNA PGR
15 chickenpox 10.1 ACTC1 PGR
16 myoma 10.1 MED12 PGR
17 peritoneal benign neoplasm 10.1 MED12 PGR
18 diffuse peritoneal leiomyomatosis 10.1 MED12 PGR
19 leiomyomatosis 10.1 MED12 PGR
20 angiomyolipoma 10.1 ACTC1 PGR
21 breast benign neoplasm 10.1 MED12 PGR
22 spindle cell carcinoma 10.1 ACTC1 PGR
23 thoracic benign neoplasm 10.1 MED12 PGR
24 uterine benign neoplasm 10.1 MED12 PGR
25 reproductive organ benign neoplasm 10.1 MED12 PGR
26 breast fibroadenoma 10.0 MED12 PGR
27 gastric leiomyoma 10.0
28 vulvar dystrophy 10.0 CDKN2A PGR
29 bartholin's gland benign neoplasm 10.0 CDKN2A PGR
30 endometrial squamous cell carcinoma 10.0 CDKN2A PGR
31 endometrial mucinous adenocarcinoma 10.0 CDKN2A PGR
32 adenoid basal cell carcinoma 10.0 CDKN2A PGR
33 bartholin's gland disease 10.0 CDKN2A PGR
34 oral leukoplakia 9.9 CDKN2A PCNA
35 suppressor of tumorigenicity 3 9.9 CDKN2A PCNA
36 pre-malignant neoplasm 9.9 CDKN2A PGR
37 retroperitoneum carcinoma 9.9 CDKN2A SMTN
38 juvenile nasopharyngeal angiofibroma 9.9 ACTC1 PCNA PGR
39 endometrial stromal sarcoma 9.9 ACTC1 PCNA PGR
40 in situ carcinoma 9.9 CDKN2A PGR
41 ischemic fasciitis 9.9 ACTC1 CDKN2A
42 sarcoma 9.9
43 bladder leiomyoma 9.9
44 spindle cell sarcoma 9.9
45 uterine sarcoma 9.9
46 inverted papilloma 9.9 CDKN2A PCNA
47 dedifferentiated liposarcoma 9.9 ACTC1 CDKN2A
48 papilloma 9.9 CDKN2A PCNA
49 necrotizing sialometaplasia 9.9 ACTC1 CDKN2A
50 cervical adenocarcinoma 9.9 CDKN2A PGR
51 chondromyxoid fibroma 9.9 ACTC1 CDKN2A
52 uterine anomalies 9.9 CDKN2A PGR
53 actinic keratosis 9.9 CDKN2A PCNA
54 grade iii astrocytoma 9.8 CDKN2A PCNA
55 female reproductive system disease 9.8 CDKN2A PGR
56 oral cancer 9.8 CDKN2A PCNA
57 reproductive system disease 9.8 CDKN2A PGR
58 bladder cancer 9.8
59 leiomyoma, uterine 9.8
60 uterine inversion 9.8
61 endometrial adenocarcinoma 9.7 CDKN2A PGR
62 meningioma, familial 9.7 CDKN2A PCNA PGR
63 glycogen-rich clear cell breast carcinoma 9.7 ACTC1 CDKN2A PGR
64 malignant peripheral nerve sheath tumor 9.6 ACTC1 CDKN2A
65 oligodendroglioma 9.5 CDKN2A PCNA

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:



Diseases related to Bizarre Leiomyoma

Symptoms & Phenotypes for Bizarre Leiomyoma

MGI Mouse Phenotypes related to Bizarre Leiomyoma:

47 (showing 3, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.55 ACTC1 CDKN2A MED12 PGR SMTN
2 mortality/aging MP:0010768 9.43 ACTC1 CDKN2A MED12 PCNA PGR SMTN
3 muscle MP:0005369 8.92 ACTC1 CDKN2A PGR SMTN

Drugs & Therapeutics for Bizarre Leiomyoma

Search Clinical Trials , NIH Clinical Center for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

Anatomical Context for Bizarre Leiomyoma

MalaCards organs/tissues related to Bizarre Leiomyoma:

42
Breast, Smooth Muscle, Prostate, Uterus

Publications for Bizarre Leiomyoma

Articles related to Bizarre Leiomyoma:

(showing 22, show less)
# Title Authors Year
1
Bizarre leiomyoma of uterus/smooth muscle tumor of uncertain malignant potential: A diagnostic dilemma. ( 26960523 )
2015
2
Bizarre leiomyoma of the scrotum: A case report and review of the literature. ( 24765204 )
2014
3
Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report. ( 21812974 )
2011
4
Bizarre leiomyoma of the posterior vaginal fornix. ( 18501906 )
2008
5
A rare symplastic or bizarre leiomyoma of the scrotum: a case report and review of the literature. ( 19068127 )
2008
6
Bizarre leiomyoma of scrotum. ( 16146275 )
2005
7
Bizarre leiomyoma of the soft tissue. ( 16194835 )
2005
8
Pathologic quiz case: a 69-year-old asymptomatic man with a scrotal mass. Atypical (symplastic or bizarre) leiomyoma of the scrotum. ( 14736263 )
2004
9
Bizarre leiomyoma of the scrotum. ( 12808340 )
2003
10
Atypical (bizarre) leiomyoma of the nasal cavity with prominent myxoid change. ( 12401830 )
2002
11
[A clinicopathological study of bizarre leiomyoma]. ( 12485480 )
2002
12
Bizarre leiomyoma of the vagina: report of a case. ( 10782419 )
2000
13
Bizarre leiomyoma of the epididymis. A case report. ( 11517827 )
2000
14
Bizarre leiomyoma of the prostate. ( 9126110 )
1997
15
Neoplastic association of leiomyoma, bizarre leiomyoma and leiomyosarcoma uteri. Case report. ( 7828608 )
1994
16
Complex karyotypic anomalies in a bizarre leiomyoma of the uterus. ( 2487152 )
1989
17
Bizarre leiomyoma of the renal pelvis with ultrastructural and immunohistochemical findings. ( 2926892 )
1989
18
Bizarre leiomyoma of the prostate. ( 3125678 )
1988
19
Uterine bizarre leiomyoma. ( 7113686 )
1982
20
Bizarre leiomyoma of the stomach: Case report. ( 5266968 )
1970
21
A comprative electron microscopic study of a leiomyosarcoma and bizarre leiomyoma (leiomyoblastoma) of the stomach. ( 5820970 )
1969
22
Bizarre leiomyoma (leiomyoblastoma). Report of a case. ( 14009016 )
1962

Variations for Bizarre Leiomyoma

Expression for Bizarre Leiomyoma

Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for Bizarre Leiomyoma

Pathways related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

(showing 1, show less)
# Super pathways Score Top Affiliating Genes
1 10.65 CDKN2A PCNA

GO Terms for Bizarre Leiomyoma

Sources for Bizarre Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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