Bladder Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Bladder Benign Neoplasm

MalaCards integrated aliases for Bladder Benign Neoplasm:

Name: Bladder Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Nephrological diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Neoplasms

Benign neoplasms

Benign neoplasm of urinary organs

Benign neoplasm: Bladder

External Ids:

Disease Ontology ¹² DOID:0050623

ICD10 ³² D30.3

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Summaries for Bladder Benign Neoplasm

Disease Ontology : ¹² A urinary system benign neoplasm located in the bladder including papillomas, leiomyomas, fibromas, hemangiomas, neurofibromas and lipomas.

MalaCards based summary : Bladder Benign Neoplasm is related to bladder leiomyoma and cervical adenocarcinoma. An important gene associated with Bladder Benign Neoplasm is KRT7 (Keratin 7), and among its related pathways/superpathways is ID signaling pathway. Affiliated tissues include bladder including papillomas.

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Related Diseases for Bladder Benign Neoplasm

Diseases related to Bladder Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)

#	Related Disease	Score	Top Affiliating Genes
1	bladder leiomyoma	11.1
2	cervical adenocarcinoma	10.1	KRT7 KRT20
3	neuroendocrine carcinoma	10.1	KRT7 KRT20
4	cystitis	10.1	KRT7 KRT20
5	teratoma	10.1	KRT7 KRT20
6	urethral villous adenoma	10.1	KRT7 KRT20
7	villous adenoma	10.1	KRT7 KRT20
8	epithelial predominant wilms' tumor	10.1	KRT7 AMACR
9	atrophic vulva	10.1	KRT7 KRT20
10	pancreatic serous cystadenocarcinoma	10.1	KRT7 KRT20
11	urinary bladder villous adenoma	10.1	KRT7 KRT20
12	vulva adenocarcinoma	10.1	KRT7 KRT20
13	vaginal tubulovillous adenoma	10.1	KRT7 KRT20
14	cystitis cystica	10.1	KRT7 KRT20
15	mucinous ovarian cystadenoma	10.1	KRT7 KRT20
16	cystadenoma	10.1	KRT7 KRT20
17	rectosigmoid junction neoplasm	10.1	KRT7 KRT20
18	transverse colon cancer	10.1	KRT7 KRT20
19	sigmoid neoplasm	10.1	KRT7 KRT20
20	urinary bladder small cell neuroendocrine carcinoma	10.1	KRT7 KRT20
21	vulvar apocrine adenocarcinoma	10.1	KRT7 KRT20
22	eyelid carcinoma	10.1	KRT7 KRT20
23	jejunal neoplasm	10.1	KRT7 KRT20
24	jejunal cancer	10.1	KRT7 KRT20
25	clear cell papillary renal cell carcinoma	10.1	KRT7 AMACR
26	colonic lymphangioma	10.1	KRT7 KRT20
27	chromophil adenoma of the kidney	10.1	KRT7 AMACR
28	intratubular embryonal carcinoma	10.1	KRT7 KRT20
29	malignant syringoma	10.1	KRT7 KRT20
30	papillary transitional carcinoma	10.1	KRT7 KRT20
31	anal canal adenocarcinoma	10.1	KRT7 KRT20
32	appendix adenocarcinoma	10.1	KRT7 KRT20
33	supine hypotensive syndrome	10.1	KRT7 KRT20
34	mucinous bronchioloalveolar adenocarcinoma	10.1	KRT7 KRT20
35	jejunal adenocarcinoma	10.1	KRT7 KRT20
36	meibomian cyst	10.1	KRT7 KRT20
37	acute orbital inflammation	10.1	KRT7 KRT20
38	gastric diffuse adenocarcinoma	10.1	KRT7 KRT20
39	eccrine sweat gland cancer	10.1	KRT7 KRT20
40	sweat gland cancer	10.1	KRT7 KRT20
41	pancreatic mucinous cystadenoma	10.1	KRT7 KRT20
42	linitis plastica	10.1	KRT7 KRT20
43	squamous papillomatosis	10.1	KRT7 KRT20
44	mucinous tubular and spindle renal cell carcinoma	10.1	KRT7 AMACR
45	vaginal adenoma	10.1	KRT7 KRT20
46	ovarian brenner tumor	10.1	KRT7 KRT20
47	vaginal benign neoplasm	10.1	KRT7 KRT20
48	lung leiomyosarcoma	10.1	KRT7 KRT20
49	clear cell basal cell carcinoma	10.1	KRT7 KRT20
50	prostate neuroendocrine neoplasm	10.1	KRT7 KRT20

Graphical network of the top 20 diseases related to Bladder Benign Neoplasm:

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Symptoms & Phenotypes for Bladder Benign Neoplasm

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Drugs & Therapeutics for Bladder Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Bladder Benign Neoplasm

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Genetic Tests for Bladder Benign Neoplasm

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Anatomical Context for Bladder Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Bladder Benign Neoplasm:

¹⁹

Bladder Including Papillomas

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Publications for Bladder Benign Neoplasm

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Genes for Bladder Benign Neoplasm

Genes related to Bladder Benign Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KRT7	Keratin 7	Protein Coding	6.18	DISEASES inferred ¹⁵
2	AMACR	Alpha-Methylacyl-CoA Racemase	Protein Coding	5.94	DISEASES inferred ¹⁵
3	PAX2	Paired Box 2	Protein Coding	5.77	DISEASES inferred ¹⁵
4	PAX8	Paired Box 8	Protein Coding	5.29	DISEASES inferred ¹⁵
5	KRT20	Keratin 20	Protein Coding	5.08	DISEASES inferred ¹⁵

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Variations for Bladder Benign Neoplasm

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Expression for Bladder Benign Neoplasm

Search GEO for disease gene expression data for Bladder Benign Neoplasm.

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Pathways for Bladder Benign Neoplasm

Pathways related to Bladder Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	ID signaling pathway ¹	9.83	PAX8 PAX2

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GO Terms for Bladder Benign Neoplasm

Biological processes related to Bladder Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 20)

#	Name	GO ID	Score	Top Affiliating Genes
1	cornification	GO:0070268	9.59	KRT7 KRT20
2	anatomical structure development	GO:0048856	9.58	PAX8 PAX2
3	inner ear morphogenesis	GO:0042472	9.58	PAX8 PAX2
4	branching involved in ureteric bud morphogenesis	GO:0001658	9.57	PAX2 PAX8
5	positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	9.56	PAX2 PAX8
6	urogenital system development	GO:0001655	9.55	PAX2 PAX8
7	mesonephros development	GO:0001823	9.54	PAX2 PAX8
8	mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0003337	9.52	PAX2 PAX8
9	pronephros development	GO:0048793	9.51	PAX2 PAX8
10	regulation of metanephric nephron tubule epithelial cell differentiation	GO:0072307	9.49	PAX2 PAX8
11	metanephric epithelium development	GO:0072207	9.48	PAX2 PAX8
12	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0072108	9.46	PAX2 PAX8
13	metanephric distal convoluted tubule development	GO:0072221	9.43	PAX2 PAX8
14	metanephric nephron tubule formation	GO:0072289	9.4	PAX2 PAX8
15	pronephric field specification	GO:0039003	9.37	PAX2 PAX8
16	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	GO:0072305	9.32	PAX2 PAX8
17	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	GO:1900212	9.26	PAX2 PAX8
18	negative regulation of apoptotic process involved in metanephric collecting duct development	GO:1900215	9.16	PAX2 PAX8
19	negative regulation of apoptotic process involved in metanephric nephron tubule development	GO:1900218	8.96	PAX2 PAX8
20	positive regulation of metanephric DCT cell differentiation	GO:2000594	8.62	PAX2 PAX8

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Sources for Bladder Benign Neoplasm

¹ BioSystems

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⁵⁷ OMIM® (Updated 05-Apr-2021)

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⁷⁰ UMLS

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⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia