MCID: BLD041
MIFTS: 33

Bladder Calculus

Categories: Nephrological diseases
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Aliases & Classifications for Bladder Calculus

MalaCards integrated aliases for Bladder Calculus:

Name: Bladder Calculus 11 14 16
Urinary Bladder Calculi 43 71
Urinary Bladder Calculus 33
Urinary Bladder Stone 33
Vesical Calculus 33
Bladder Calculi 33
Vesical Calculi 33
Vesicolithiasis 33
Cystic Calculus 33
Cystolithiasis 33
Cystic Calculi 33
Bladder Stone 33

Classifications:



External Ids:

Disease Ontology 11 DOID:11355
MeSH 43 D001744
SNOMED-CT 68 155879005
ICD10 31 N21.0
ICD11 33 197850369
UMLS 71 C0005683

Summaries for Bladder Calculus

MalaCards based summary: Bladder Calculus, also known as urinary bladder calculi, is related to urinary tract infection and pyuria. An important gene associated with Bladder Calculus is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways is tRNA processing. The drug Liver Extracts has been mentioned in the context of this disorder. Affiliated tissues include prostate, spinal cord and kidney.

Related Diseases for Bladder Calculus

Diseases related to Bladder Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 urinary tract infection 30.2 UPK1A KLK3
2 pyuria 30.0 NUMA1 KLK3
3 neurogenic bladder 30.0 UPK1A KLK3
4 chronic cystitis 29.9 UPK1A NUMA1
5 phosphoribosylpyrophosphate synthetase superactivity 11.1
6 bile duct cysts 10.3
7 cystitis 10.2
8 kidney disease 10.2
9 brugada syndrome 10.1
10 hydrocephalus 10.1
11 bladder cancer 10.1
12 bladder neck obstruction 10.1
13 acute kidney failure 10.1
14 nephrolithiasis 10.1
15 spinal cord injury 10.1
16 urogenital tuberculosis 10.1 SLC26A6 KLK3
17 nephrolithiasis, calcium oxalate 10.0
18 ureterocele 10.0
19 urinary tract infections, recurrent 10.0
20 inguinal hernia 10.0
21 urolithiasis 10.0
22 hydronephrosis 10.0
23 neural tube defects 10.0
24 meningocele 10.0
25 diarrhea 10.0
26 pelvic organ prolapse 10.0
27 prostatic adenoma 10.0
28 primary hyperoxaluria 10.0
29 adenoma 10.0
30 vesicoureteral reflux 10.0
31 disorder of glyoxylate metabolism 10.0
32 ataxia with vitamin e deficiency 10.0
33 cholelithiasis 10.0
34 squamous cell carcinoma 10.0
35 cholecystitis 10.0
36 nutritional deficiency disease 10.0
37 ureteral obstruction 10.0
38 osteogenic sarcoma 10.0
39 metabolic acidosis 10.0
40 obstructive nephropathy 10.0
41 cysticercosis 10.0
42 focal segmental glomerulosclerosis 10.0
43 typhoid fever 10.0
44 acromegaly 10.0
45 carcinosarcoma 10.0
46 prostate disease 10.0
47 non-invasive bladder papillary urothelial neoplasm 10.0
48 amyloidosis 10.0
49 renal tuberculosis 10.0
50 posttransplant acute limbic encephalitis 10.0

Graphical network of the top 20 diseases related to Bladder Calculus:



Diseases related to Bladder Calculus

Symptoms & Phenotypes for Bladder Calculus

Drugs & Therapeutics for Bladder Calculus

Drugs for Bladder Calculus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones Unknown status NCT03630926
2 Transurethral Versus Percutaneous Endoscopic Management of Bladder Stones in Boys: A Comparative Prospective Randomized Study Completed NCT03294239
3 RISK FACTORS OF GALL BLADDER STONE FORMATION Completed NCT04822519
4 Clipless Laparoscopic Cholecystectomy Using Harmonic Scalpel in Cirrhotic Patients a Prospective Randomized Study Completed NCT01009450
5 Efficacy of the Act of Urination to Relief the Pain During Flexible Cystoscopy Procedure. Recruiting NCT05207969
6 A Multicenter, Single-blind, Observational Clinical Trial of URISAFE Recruiting NCT05337189

Search NIH Clinical Center for Bladder Calculus

Cochrane evidence based reviews: urinary bladder calculi

Genetic Tests for Bladder Calculus

Anatomical Context for Bladder Calculus

Organs/tissues related to Bladder Calculus:

MalaCards : Prostate, Spinal Cord, Kidney, Liver, Uterus, Pancreas, Bone

Publications for Bladder Calculus

Articles related to Bladder Calculus:

(show top 50) (show all 1722)
# Title Authors PMID Year
1
Incarcerated Procidentia Caused by Multiple Vesical Calculi: A Rare Case Report. 62
36457439 2022
2
Successful engraftment of bladder organoids in de-epithelialized mouse colon. 62
36449180 2022
3
Retrospective comparison of open vs minimally invasive cystotomy in 28 cats using a composite outcome score. 62
34904482 2022
4
Stone Formation Due to Migration of Hemostatic Clip After Robot-Assisted Laparoscopic Radical Prostatectomy: A Late and Rare Presentation. 62
36465783 2022
5
May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications? 62
34529244 2022
6
Stone disease in low- and middle-income countries: could augmented reality have a role in its management? 62
35993671 2022
7
Acute Cholelithiasis With Acute Pancreatic Calcifications: A Unique Presentation of Sickle Cell Crisis. 62
36381715 2022
8
Diagnosis and management of choledochal cysts. 62
36257874 2022
9
IUCD as bladder stone. 62
35770316 2022
10
Orthotopic ureterocele with concurrent ureteral urothelial carcinoma in a dog. 62
35820027 2022
11
Glossary of pre-settings given by laser companies: no consensus! 62
35933626 2022
12
Comparison of three different modalities for the treatment of bladder calculi by size. 62
34058930 2022
13
Comparison of two different minimally invasive techniques used in bladder stone surgery for preschool-aged children. 62
36326399 2022
14
Giant bladder stone: A case report. 62
35837049 2022
15
A childhood blast victim presenting with bladder stone in adulthood-A rare case report of retained blast fragment with secondary stone. 62
35444927 2022
16
Giant Bladder Stone: A Case Report and Literature Review. 62
35992289 2022
17
A giant vesical calculus. 62
35983122 2022
18
Incomplete sagittal septum of the bladder with cystolithiasis. 62
35795107 2022
19
[Robot-assisted laparoscopic bladder diverticulum resection (RABDR)]. 62
33975364 2022
20
Suprapubic catheter encasement by bladder stone. 62
35346532 2022
21
Vesicovaginal fistula with bladder and vaginal stone. 62
35803097 2022
22
First reported case of incidental complete passage of multiple vesical calculi after vaginal packing of edematous and ulcerated procidentia. 62
34661683 2022
23
Giant bladder stone resulting in acute kidney injury; A case report and review of literature. 62
35070725 2022
24
Giant Bladder Stone: A Case Report. 62
35774646 2022
25
Bladder stone causing vesicovaginal fistula and migration into the vagina. 62
35534044 2022
26
Giant bladder stone resulting in renal failure and concurrent bladder cancer: A case report. 62
35658321 2022
27
Percutaneous and endoscopic combined treatment of bladder and renal lithiasis in mitrofanoff conduit. 62
35263058 2022
28
Bipolar transurethral enucleation of the prostate combined with open cystolithotomy in the treatment of large and giant prostate with bladder stones: Case series. 62
33784912 2022
29
Assessing the Complications of Monopolar Transurethral Resection of the Prostate (M-TURP) Using Clavien-Dindo Complications Grading System. 62
35813687 2022
30
A Case Report of Endoscopic Retrograde Cholangiopancreatography (ERCP) and Acute Pancreatitis Induced Takotsubo Cardiomyopathy (TCM) in a Patient With Gallstones Induced Acute Pancreatitis and Cholangitis. 62
35663673 2022
31
AKI in a Patient with Urinary Tract Infection, Urinary Crystals, and a Bladder Stone. 62
35721621 2022
32
Bladder stones in a herniated bladder: A rare case report and literature review. 62
35286982 2022
33
Assess the safety and effectiveness of a novel approach during transurethral pneumatic cystolithotripsy in large urinary bladder stone: quasi-clinical trial. 62
34853892 2022
34
Ectopic intrauterine device in the bladder causing cystolithiasis: A case report. 62
35611133 2022
35
Complications and Comorbidities in Foals Undergoing Surgical Repair for Uroperitoneum. 62
34958882 2022
36
Assessment of Bacterial Communities Within the Biofilm of Bladder Calculi in the Neurogenic Bladder Rat Model Following Spinal Cord Injury. 62
35368183 2022
37
Ample dietary fat reduced the risk of primary vesical calculi by inducing macrophages to engulf budding crystals in mice. 62
35256944 2022
38
A 17-year-old indwelling ureteral stent with large vesical calculus at one end: The tombstone of a forgotten Double "J" stent. 62
35360771 2022
39
Synchronous transurethral cystolitholapaxy and TURP reveals better results than transurethral cystolitholapaxy plus medical therapy for BPH: a randomized prospective study on 100 patients with concomitant urinary bladder stone(s) and BPH. 62
34807286 2022
40
Holmium laser enucleation versus bipolar resection in the management of large-volume benign prostatic hyperplasia: A randomized controlled trial. 62
34788900 2022
41
One-stage laparoscopy combined with resectoscope in the treatment of huge bladder diverticulum, multiple stones in diverticulum, multiple stones in bladder and benign prostatic hyperplasia: A case report. 62
36388908 2022
42
Transurethral enucleation of the prostate combined with laparoscopic bladder diverticulectomy. 62
32432482 2022
43
Coincidental finding of a giant bladder calculus and squamous cell carcinoma of bladder: A case report. 62
35449528 2022
44
Primary Hyperoxaluria Type 3 Can Also Result in Kidney Failure: A Case Report. 62
34245816 2022
45
Utilizing trans-scrotal percutaneous cystolitholapaxy in the case of massive inguinoscrotal herniation of the bladder with concomitant bladder calculi. 62
34820288 2022
46
Hypoglycemia with lactic acidosis caused by a new MRPS2 gene mutation in a Chinese girl: a case report. 62
34991560 2022
47
Comprehensive proteomic quantification of bladder stone progression in a cystinuric mouse model using data-independent acquisitions. 62
35771811 2022
48
Jackstone: A Calculus "Toy" in the Bladder. A Case Report of Rare Entity and Comprehensive Review of the Literature. 62
36061940 2022
49
Giant urinary bladder calculi in a 60-year-old man: a case report. 62
35382051 2022
50
Percutaneous cystolithotripsy of bladder stones in children: A case series, an experience from a tertiary hospital. 62
35197709 2022

Variations for Bladder Calculus

Expression for Bladder Calculus

Search GEO for disease gene expression data for Bladder Calculus.

Pathways for Bladder Calculus

Pathways related to Bladder Calculus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.3 TPRKB TP53RK OSGEP LAGE3

GO Terms for Bladder Calculus

Cellular components related to Bladder Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 EKC/KEOPS complex GO:0000408 9.23 TPRKB TP53RK OSGEP LAGE3

Biological processes related to Bladder Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus organization GO:0006997 9.56 WDR73 NUMA1
2 tRNA threonylcarbamoyladenosine metabolic process GO:0070525 9.46 TP53RK LAGE3
3 tRNA threonylcarbamoyladenosine modification GO:0002949 9.26 TPRKB OSGEP
4 tRNA processing GO:0008033 9.1 TPRKB TP53RK OSGEP LAGE3

Sources for Bladder Calculus

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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