MCID: BLD023
MIFTS: 32

Bladder Leiomyoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Bladder Leiomyoma

MalaCards integrated aliases for Bladder Leiomyoma:

Name: Bladder Leiomyoma 12 15 70
Leiomyoma of the Urinary Bladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13109
NCIt 50 C6178
UMLS 70 C1332560

Summaries for Bladder Leiomyoma

Disease Ontology : 12 A bladder benign neoplasm that derives from smooth muscle cells.

MalaCards based summary : Bladder Leiomyoma, also known as leiomyoma of the urinary bladder, is related to leiomyoma and rare tumor. An important gene associated with Bladder Leiomyoma is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Nanog in Mammalian ESC Pluripotency and C-MYB transcription factor network. Affiliated tissues include smooth muscle, breast and kidney, and related phenotypes are integument and normal

Related Diseases for Bladder Leiomyoma

Diseases related to Bladder Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 317)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 31.2 VIM KIT GNRH1 CD34
2 rare tumor 30.8 KIT EWSR1
3 neurofibromatosis, type i 30.0 KIT EWSR1 CD34
4 myoma 29.9 KIT GNRH1 CD34 CALD1
5 renal oncocytoma 29.8 VIM KRT7 KIT
6 oncocytoma 29.8 VIM KRT7 KIT
7 cystitis 29.7 VIM KRT7 KIT
8 lipomatosis, multiple 29.7 KIT EWSR1 CD34 CALD1 ANO1
9 mesenchymal cell neoplasm 29.5 ROS1 PDGFRB KIT EWSR1 CD34 CALD1
10 gastrointestinal stromal tumor 29.2 VIM PDGFRB KIT CD34 ANO1
11 urethra leiomyoma 10.4 KIT CALD1
12 diffuse peritoneal leiomyomatosis 10.4 GNRH1 CALD1
13 small cell sarcoma 10.4 EWSR1 CALD1
14 spinal cord sarcoma 10.4 KIT CD34
15 gallbladder leiomyoma 10.4 KIT CD34
16 gastric leiomyosarcoma 10.4 KIT ANO1
17 neuronal intestinal dysplasia, type b 10.3 KIT CD34
18 vulvar sarcoma 10.3 EWSR1 CD34
19 intravascular angioleiomyoma 10.3 CD34 CALD1
20 gastric hemangioma 10.3 KIT ANO1
21 breast myofibroblastoma 10.3 CD34 CALD1
22 mucocele of appendix 10.3 KIT CD34
23 ovarian fibrothecoma 10.3 KIT CALB2
24 vulvar leiomyosarcoma 10.3 CD34 CALD1
25 retroperitoneal hemangiopericytoma 10.3 KIT CD34
26 parasagittal meningioma 10.3 CD34 ANO1
27 glomangiosarcoma 10.3 CD34 CALD1
28 plexiform schwannoma 10.3 KIT CD34
29 heart sarcoma 10.3 KIT CD34
30 ovarian melanoma 10.3 CALD1 CALB2
31 cutaneous ganglioneuroma 10.3 KIT CD34
32 cervical polyp 10.3 CD34 CALD1
33 intravenous leiomyomatosis 10.3 CD34 CALD1
34 sarcomatoid squamous cell skin carcinoma 10.3 CD34 CALD1
35 congenital granular cell tumor 10.3 CD34 CALD1
36 subungual glomus tumor 10.3 CD34 CALD1
37 vulvar leiomyoma 10.3 CD34 CALD1
38 active peptic ulcer disease 10.3 KIT ANO1
39 breast malignant phyllodes tumor 10.3 KIT CD34
40 pacinian tumor 10.3 CD34 CALB2
41 kidney hemangiopericytoma 10.3 CD34 CALB2
42 extraosseous osteosarcoma 10.3 CD34 CALD1
43 pineal region teratoma 10.3 MYOD1 KIT
44 central nervous system mesenchymal non-meningothelial tumor 10.3 MYOD1 EWSR1
45 conventional leiomyosarcoma 10.3 MYOD1 CALD1
46 ovarian endometrioid stromal sarcoma 10.3 CALD1 CALB2
47 testicular gonadoblastoma 10.3 VIM KIT
48 inflammatory leiomyosarcoma 10.3 MYOD1 CALD1
49 malignant fibrous histiocytoma of bone 10.3 MYOD1 CALD1
50 small intestinal sarcoma 10.3 KIT EWSR1 ANO1

Graphical network of the top 20 diseases related to Bladder Leiomyoma:



Diseases related to Bladder Leiomyoma

Symptoms & Phenotypes for Bladder Leiomyoma

MGI Mouse Phenotypes related to Bladder Leiomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.92 ANO1 CD34 DICER1 GNRH1 KIT PDGFRB
2 normal MP:0002873 9.76 CALB2 DICER1 GNRH1 KIT MYOD1 PDGFRB
3 neoplasm MP:0002006 9.73 CD34 DICER1 GNRH1 KIT MYOD1 STAT6
4 renal/urinary system MP:0005367 9.56 ANO1 DICER1 GNRH1 KIT KRT7 PDGFRB
5 reproductive system MP:0005389 9.28 DICER1 GNRH1 KIT MYOD1 PDGFRB ROS1

Drugs & Therapeutics for Bladder Leiomyoma

Search Clinical Trials , NIH Clinical Center for Bladder Leiomyoma

Genetic Tests for Bladder Leiomyoma

Anatomical Context for Bladder Leiomyoma

MalaCards organs/tissues related to Bladder Leiomyoma:

40
Smooth Muscle, Breast, Kidney, Ovary, Small Intestine, Liver, Lung

Publications for Bladder Leiomyoma

Articles related to Bladder Leiomyoma:

(show top 50) (show all 169)
# Title Authors PMID Year
1
Open Partial Cystectomy of Intramural Bladder Leiomyoma With Unfavorable Position: A Rare Case Report. 61
33659116 2021
2
Bladder Leiomyoma. 61
33412310 2021
3
Transvesical laparoscopy for bladder leiomyoma excision: a novel surgical technique. 61
33064155 2020
4
Transurethral resection of a bladder trigone leiomyoma: a rare case report. 61
33028269 2020
5
A large bladder leiomyoma. 61
32322534 2020
6
Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura. 61
32158588 2020
7
Not All Pediatric Bladder Masses are Rhabdomyosarcoma: Report of a Rare Case With Review of the Literature. 61
30299349 2019
8
[Bladder leiomyomas.] 61
31274128 2019
9
Partial cystectomy in young male for a urachal tumor masquerading a bladder leiomyoma. 61
30932431 2019
10
Transurethral Enucleation of Bladder Leiomyoma: A Series of Six Cases and Review of the Literature. 61
30227443 2019
11
Cystoscope-Assisted Laparoscopic Enucleation of a Large Progressive Bladder Leiomyoma. 61
32775643 2019
12
Bladder Leiomyoma: A Rare Differential and a Potential Pitfall in the Evaluation for a Bladder Mass in 18F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography. 61
29962734 2018
13
Spontaneous Urinary Bladder Leiomyoma in a Rhesus Macaque (Macaca mulatta). 61
29857795 2018
14
Vaginal ultrasound for imaging of a urinary bladder mass and treatment of a large leiomyoma of the urinary bladder in pregnancy. 61
29147754 2018
15
Rare symptomatic bladder leiomyoma: case report and literature review. 61
29436249 2018
16
Incidental Asymptomatic Leiomyoma of the Urinary Bladder. 61
29122624 2018
17
[Urethral leiomyoma]. 61
29634147 2018
18
Total Laparoscopic Treatment With Cystotomy for Intramural Bladder Leiomyoma. 61
28373126 2018
19
The Rare Togetherness of Bladder Leiomyoma and Neurofibromatosis. 61
29736289 2018
20
Leiomyoma of the urinary bladder. 61
28924293 2017
21
Cystoscopic Evaluation of Bladder Leiomyoma. 61
28161381 2017
22
Bladder leiomyoma. 61
28794597 2017
23
Transurethral Resection of a Large Urinary Bladder Leiomyoma: A Rare Case Report. 61
28670675 2017
24
Bladder Leiomyoma. 61
28406781 2017
25
Bladder leiomyoma in male patient presenting with renal oncocytoma: Are the two conditions related? 61
27453673 2016
26
Bladder leiomyoma presenting as dyspareunia: Case report and literature review. 61
27428187 2016
27
Large leiomyoma of the bladder masquerading as an enlarged prostate gland. 61
26907817 2016
28
Leiomyoma of Urinary Bladder Presenting with Febrile Urinary Tract Infection: A Case Report. 61
27621100 2016
29
Total endoscopic management of a large bladder leiomyoma. 61
26692681 2015
30
Transvaginal Resection of a Bladder Leiomyoma Misdiagnosed with a Vaginal Mass: A Case Report and Literature Review. 61
26693368 2015
31
Leiomyoma of the urinary bladder. 61
25603641 2014
32
Bladder Leiomyoma Presenting With LUTS and Coexisting Bladder and Uterine Leiomyomata: A Review of Two Cases. 61
24791156 2014
33
Transurethral resection of a bladder leiomyoma: A case report. 61
24554974 2014
34
Imaging findings of atypical leiomyoma of the urinary bladder simulating bladder cancer: a case report and literature review. 61
23702508 2013
35
Leiomyoma of the urinary bladder: a case report. 61
23849576 2013
36
Endovesical leiomyoma of bladder: a case report. 61
23787498 2013
37
Bladder leiomyoma. 61
23337189 2013
38
Bladder leiomyoma: Presentation, evaluation and treatment. 61
26579246 2013
39
Transvesical enucleation of multiple leiomyoma of bladder and urethra. 61
23577337 2013
40
Leiomyoma of the urinary bladder in asymptomatic women. 61
23248525 2012
41
Influence of clinical characteristics and tumor size on symptoms of bladder leiomyoma: a pooled analysis of 61 cases. 61
22882917 2012
42
Bladder leiomyoma in a 6-year-old boy. 61
21820699 2012
43
Cystoscopic enucleation of bladder leiomyoma. 61
22346100 2012
44
Bladder leiomyoma: a case report. 61
22187802 2011
45
Presentation of bladder leiomyoma concurrent with transitional cell carcinoma. 61
21333053 2011
46
Laparoscopic enucleation of leiomyoma of the urinary bladder: a case report and review of the literature. 61
21656478 2011
47
Leiomyoma of the urinary bladder: a series of nine cases and review of the literature. 61
20947147 2010
48
Laparoscopic enucleation of a bladder leiomyoma. 61
19896608 2009
49
Leiomyoma of the urinary bladder presenting as urinary retention in the female. 61
19671234 2009
50
Leiomyoma of the urinary bladder with bladder stone. 61
18803905 2008

Variations for Bladder Leiomyoma

Expression for Bladder Leiomyoma

Search GEO for disease gene expression data for Bladder Leiomyoma.

Pathways for Bladder Leiomyoma

Pathways related to Bladder Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.78 WNT4 VIM ROS1 PDGFRB KIT GNRH1
2 11.22 MYOD1 KIT CD34
3 10.9 WNT4 MYOD1 KIT CD34
4 10.26 VIM ROS1 PDGFRB KIT GNRH1

GO Terms for Bladder Leiomyoma

Cellular components related to Bladder Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.44 WNT4 VIM STAT6 PDGFRB MYOD1 KRT7
2 cell surface GO:0009986 9.35 WNT4 ROS1 PDGFRB KIT CD34

Biological processes related to Bladder Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 9.61 ROS1 PDGFRB KIT
2 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.58 ROS1 PDGFRB KIT
3 negative regulation of gene expression GO:0010629 9.56 WNT4 ROS1 DICER1 CD34
4 male gonad development GO:0008584 9.54 WNT4 PDGFRB KIT
5 multicellular organism development GO:0007275 9.5 WNT4 ROS1 PDGFRB MYOD1 KIT GNRH1
6 positive regulation of kinase activity GO:0033674 9.33 ROS1 PDGFRB KIT
7 positive regulation of phospholipase C activity GO:0010863 9.32 PDGFRB KIT
8 positive regulation of collagen biosynthetic process GO:0032967 8.8 WNT4 VIM PDGFRB

Molecular functions related to Bladder Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.13 ROS1 PDGFRB KIT
2 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 ROS1 PDGFRB KIT

Sources for Bladder Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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