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MCID: BLD009
MIFTS: 38

Bladder Neck Obstruction

Categories: Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Bladder Neck Obstruction

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MalaCards integrated aliases for Bladder Neck Obstruction:

Name: Bladder Neck Obstruction 12 15 73
Obstruction of Bladder Neck or Vesicourethral Orifice 12
Urinary Bladder Neck Obstruction 44

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:13948
ICD10 33 N32.0
ICD9CM 35 596.0
MeSH 44 D001748
NCIt 50 C79541
SNOMED-CT 68 25220001
UMLS 73 C0005694
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Summaries for Bladder Neck Obstruction

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MalaCards based summary : Bladder Neck Obstruction, also known as obstruction of bladder neck or vesicourethral orifice, is related to urethral stricture and zika fever. An important gene associated with Bladder Neck Obstruction is SIRPA (Signal Regulatory Protein Alpha), and among its related pathways/superpathways are Adhesion and FOXA2 and FOXA3 transcription factor networks. The drugs Tamsulosin and Fesoterodine have been mentioned in the context of this disorder. Affiliated tissues include prostate, kidney and skin, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 76 Bladder neck obstruction is a condition where the bladder neck does not open enough during... more...

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Related Diseases for Bladder Neck Obstruction

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Diseases related to Bladder Neck Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 urethral stricture 10.2 KLK3 SIRPA
2 zika fever 10.2 F3 PURA
3 autonomic nervous system disease 10.1 TAC1 TTR
4 urethral diverticulum 10.1 F3 KLK3
5 nephrogenic adenoma of the urethra 10.1 ACPP KLK3
6 vertebrobasilar insufficiency 10.1 F3 SIRPA
7 analbuminemia 10.1 F3 TTR
8 skin sarcoidosis 10.1 ACE TNFRSF1B
9 granulomatous dermatitis 10.1 ACE TNFRSF1B
10 transient arthritis 10.1 F3 TNFRSF1B
11 tuberculous epididymitis 10.1 AFP KLK3
12 sexual disorder 10.1 ACE KLK3
13 male reproductive organ benign neoplasm 10.1 AFP KLK3
14 rete testis adenocarcinoma 10.1 AFP KLK3
15 seminal vesicle tumor 10.1 AFP KLK3
16 endodermal sinus tumor 10.1 AFP KLK3
17 rete testis neoplasm 10.1 AFP KLK3
18 pure autonomic failure 10.1 ACE TTR
19 intermediate coronary syndrome 10.0 ACE F3
20 melkersson-rosenthal syndrome 10.0 ACE TNFRSF1B
21 hypersensitivity reaction type iv disease 10.0 ACE TNFRSF1B
22 carpal tunnel syndrome 10.0 TAC1 TTR
23 heart conduction disease 10.0 ACE TTR
24 hepatic vascular disease 10.0 AFP F3
25 tracheal cancer 10.0 AFP TNFRSF1B
26 testicular yolk sac tumor 10.0 AFP TTR
27 diabetes insipidus, nephrogenic, autosomal 10.0
28 ureterocele 10.0
29 hydronephrosis 10.0
30 neurogenic bladder 10.0
31 diabetes insipidus 10.0
32 posterior urethral valves 10.0
33 vein disease 10.0 AFP F3
34 respiratory failure 9.9 ACE F3 TTR
35 placental insufficiency 9.9 AFP F3
36 liver cirrhosis 9.9 AFP F3 TTR
37 placenta disease 9.9 AFP F3
38 vesicoureteral reflux 1 9.8
39 prostatic hypertrophy 9.8
40 acute cystitis 9.8
41 ehlers-danlos syndrome 9.8
42 prostatitis 9.8
43 cystitis 9.8
44 uremia 9.8
45 oligohydramnios 9.8 ACE AFP

Comorbidity relations with Bladder Neck Obstruction via Phenotypic Disease Network (PDN): (show all 30)


Acute Cystitis Acute Kidney Failure
Balanoposthitis Bladder Cancer
Bladder Disease Chronic Kidney Failure
Cystitis Cystitis Cystica
Epididymo-Orchitis Gout
Hydronephrosis Kidney Disease
Lipoma of Spermatic Cord Nephrolithiasis, X-Linked Recessive, with Renal Failure
Neurogenic Bladder Peyronie's Disease
Prostate Calculus Prostate Cancer
Prostate Carcinoma in Situ Prostatic Hypertrophy
Prostatitis Prostatocystitis
Radiation Cystitis Spermatocele
Ureterolithiasis Urethral Calculus
Urethral Stricture Urethritis
Urinary Tract Obstruction Vesicoureteral Reflux 1

Graphical network of the top 20 diseases related to Bladder Neck Obstruction:



Diseases related to Bladder Neck Obstruction
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Symptoms & Phenotypes for Bladder Neck Obstruction

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MGI Mouse Phenotypes related to Bladder Neck Obstruction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.92 ACE ACPP AFP F3 PURA SIRPA
2 cardiovascular system MP:0005385 9.8 ACE F3 HCCS SIRPA TAC1 TNFRSF1B
3 endocrine/exocrine gland MP:0005379 9.63 ACE ACPP AFP PURA SP6 TNFRSF1B
4 homeostasis/metabolism MP:0005376 9.56 ACE AFP F3 HCCS PURA SIRPA
5 neoplasm MP:0002006 9.02 ACE ACPP AFP F3 TNFRSF1B
Sources

Drugs & Therapeutics for Bladder Neck Obstruction

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Drugs for Bladder Neck Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamsulosin Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 106133-20-4 129211
2
Fesoterodine Approved Phase 4 286930-03-8, 286930-02-7 6918558
3
Alfuzosin Approved, Investigational Phase 4 81403-80-7 2092
4
Doxazosin Approved Phase 4 74191-85-8 3157
5
Silodosin Approved Phase 4 160970-54-7
6
Dutasteride Approved, Investigational Phase 4 164656-23-9 6918296 152945
7
Baclofen Approved Phase 4 1134-47-0 2284
8
Ezogabine Approved, Investigational Phase 4 150812-12-7 121892
9 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
10 Adrenergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
11 Adrenergic Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
12 Adrenergic alpha-Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
13 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
14 Tolterodine tartrate Phase 4 124937-52-6
15 Cholinergic Antagonists Phase 4,Phase 2,Phase 1
16 Cholinergic Agents Phase 4,Phase 2,Phase 3,Phase 1
17 Muscarinic Antagonists Phase 4,Phase 2,Phase 1
18 Antihypertensive Agents Phase 4
19 Hormone Antagonists Phase 4
20 Steroid Synthesis Inhibitors Phase 4
21 Hormones Phase 4
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
23 5-alpha Reductase Inhibitors Phase 4
24 Coagulants Phase 4
25 Hemostatics Phase 4
26 Anticonvulsants Phase 4
27
Acetylcholine Approved Phase 2, Phase 3 51-84-3 187
28 Peripheral Nervous System Agents Phase 2, Phase 3
29 onabotulinumtoxinA Phase 2, Phase 3
30 abobotulinumtoxinA Phase 2, Phase 3
31 Neuromuscular Agents Phase 2, Phase 3
32 Acetylcholine Release Inhibitors Phase 2, Phase 3
33 Pharmaceutical Solutions Phase 2, Phase 3,Phase 1
34 Botulinum Toxins Phase 2, Phase 3
35 Botulinum Toxins, Type A Phase 2, Phase 3
36 Mirabegron Approved Phase 2 223673-61-8
37
Tadalafil Approved, Investigational Phase 2 171596-29-5 110635
38 Anesthetics Phase 1, Phase 2,Not Applicable
39 Solifenacin succinate Phase 2,Phase 1 242478-38-2
40 Adrenergic Agonists Phase 2
41 Adrenergic beta-Agonists Phase 2
42 Adrenergic beta-3 Receptor Agonists Phase 2
43 Phosphodiesterase Inhibitors Phase 2
44 Vasodilator Agents Phase 2
45 Phosphodiesterase 5 Inhibitors Phase 2
46
Bupivacaine Approved, Investigational Not Applicable 2180-92-9, 38396-39-3 2474
47 Olodaterol Approved 868049-49-4
48
Fluticasone Approved, Experimental 90566-53-3 62924
49
Budesonide Approved 51333-22-3 63006 5281004
50 Central Nervous System Depressants ,Not Applicable

Interventional clinical trials:

(show top 50) (show all 57)
# Name Status NCT ID Phase Drugs
1 Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures Unknown status NCT01196572 Phase 4
2 Ejaculatory Sparing vs. Non-ejaculatory Sparing GreenLight Laser Photoselective Vaporization of the Prostate Unknown status NCT02749604 Phase 4
3 Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction Completed NCT00147654 Phase 4 Tolterodine ER 4 mg QD;Tamsulosin 0.4 mg QD
4 An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia Completed NCT00605319 Phase 4 Toviaz (Fesoterodine)
5 The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients Completed NCT00696761 Phase 4 alfuzosin;alfuzosin;alfuzosin;alfuzosin
6 Antimuscarinics as the First-line Treatment for Male With IPSS-V/S≤1 Completed NCT01661621 Phase 4 Detrusitol 4 mg QD;Doxazosin 4 mg QD
7 Evaluation of Symptom-specific Goal Achievement Completed NCT00836823 Phase 4 Alfuzosin
8 Efficacy and Safety of Silodosin on Voiding Dysfunction Associated With Neurogenic Bladder Completed NCT01228370 Phase 4 silodosin
9 Effect of Dutasteride on Bladder Wall Hypertrophy in Patients With Benign Prostatic Obstruction Completed NCT00827814 Phase 4 Dutasteride
10 Effect of TachoSil® on Incidence of Symptomatic and Radiographic Lymphoceles After Extended Pelvic Lymph Node Dissection in Prostate and Bladder Cancer. Completed NCT02001857 Phase 4 1 TachoSil hemostatic sponge (9,5 cm x 4,8 cm) placed on each side on the external iliac artery.
11 Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen Terminated NCT01003249 Phase 4 Baclofen;Placebo
12 An Open Label Study to Evaluate the Effects of Ezogabine/Retigabine Added to Existing Anti-epileptic Drug(s) on Urinary Voiding Function in Subjects With Partial Onset Seizures Terminated NCT01607346 Phase 4 ezogabine/retigabine
13 Intraprostatic Botulinum Toxin Type "A" Injection in Patients With Benign Prostatic Hyperplasia and Unsatisfactory Response to Medical Therapy Completed NCT01566292 Phase 2, Phase 3 BOTOX
14 Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)(NX02-0022) Completed NCT01846793 Phase 3 NX-1207
15 Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH) Completed NCT01438775 Phase 3 NX-1207
16 Effectiveness and Safety of Adipose-derived Regenerative Cells for Reduction of Risk of Bladder Neck Contracture Unknown status NCT02869061 Phase 1, Phase 2
17 Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction Completed NCT00507455 Phase 2 solifenacin succinate;tamsulosin hydrochloride;Placebo to solifenacin;Placebo to tamsulosin
18 A Study of Mirabegron (YM178) in Men With Lower Urinary Tract Symptoms (LUTS) and Bladder Outlet Obstruction (BOO) Completed NCT00410514 Phase 2 Mirabegron;Placebo
19 Prophylactic Urethral Stenting With Memokath After Prostate Implantation for Prostate Adenocarcinoma Completed NCT00252941 Phase 1, Phase 2
20 Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia Completed NCT00386009 Phase 2 Tadalafil;Placebo
21 Urodynamic Effects of UK-369,003 in Men With Lower Urinary Tract Symptoms Completed NCT00408954 Phase 2 UK-369,003;UK-369,003
22 Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy Recruiting NCT02961114 Phase 1, Phase 2
23 Prostate Artery Embolization as a Treatment for Benign Prostatic Hyperplasia in Men With Prostates Larger Than 90 Grams Terminated NCT02396420 Phase 2
24 EC905 Pharmacokinetic Profile Study Completed NCT02634489 Phase 1 Tamsulosin HCl;Solifenacin Succinate;EC905
25 Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia Not yet recruiting NCT03723564 Phase 1 Lactated Ringers Solution for Injection
26 Diagnosis of Bladder Outlet Obstruction Using Dynamic Urine Vibration "Holter" in Comparison to Pressure Flow Study Unknown status NCT01388348 Not Applicable
27 Comparison Between Invasive Pressure Flow Study and Non-invasive Penile Cuff Test Unknown status NCT02031653
28 The Effect of Daily Tamsulosin 0.2mg Administration on Renal Function in Patients With Benign Prostatic Hyperplasia Unknown status NCT02033798 Not Applicable Tamsulosin
29 The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group Unknown status NCT01762007
30 Functional Changes of Urogenital System After Holmium Laser Prostatectomy Unknown status NCT02033785
31 Non-Micturation Bladder Activity in Relation to Self-Consciousness During Filling Phase and Sensation Measurement During the Filling Phase Unknown status NCT00628615
32 BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele Completed NCT03613324
33 Assessing Safety & Efficacy of MediTate Temporary Implant in Subjects With Benign Prostate Hyperplasia Completed NCT01436877 Not Applicable
34 The Role of microRNAs in Organ Remodeling in Lower Urinary Tract Dysfunction Completed NCT01482676
35 The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects Completed NCT00710749 Not Applicable
36 Impact of 80 W KTP Laser Vaporization Prostatectomy on Severity of Obstruction in Benign Prostatic Hyperplasia Completed NCT00908427 Not Applicable
37 Sensitivity and Specificity of NGAL in an Emergency Room Population Completed NCT00786708
38 Anesthetic Management in Fetoscopic Surgery and Incidence of Complications Completed NCT02434926
39 Comparative Study Between Continuous Epidural Anesthesia And Continuous Spinal Anesthesia Using Wileyâ„¢ Spinal Catheter Completed NCT01845389 Not Applicable
40 Urinary Markers for Unilateral Kidney Obstruction Completed NCT01979042
41 A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination) Completed NCT03333018 Aclidinium bromide;Aclidinium bromide/formoterol;Other COPD medication
42 PVP Compared to TURP for the Treatment of Benign Hyperplasia of the Prostate Completed NCT00527371 Not Applicable
43 Prostatic Artery Embolization in Advanced Prostate Cancer Recruiting NCT03457805 Not Applicable
44 Bipolar Transurethral Enucleation (BipolEP) vs Bipolar Transurethral Resection of the Prostate Recruiting NCT03503721 Not Applicable
45 Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity Recruiting NCT03486639
46 Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (LUTO) Recruiting NCT03281798 Not Applicable
47 Primary Care Management of Lower Urinary Tract Symptoms in Men Recruiting NCT03520673 Not Applicable
48 Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP) Recruiting NCT03062111 Not Applicable
49 A Study on Accuracy Improvement of Repeated Measure Uroflowmetry- Electromyography Recruiting NCT03399877 Not Applicable
50 Overactive Bladder (OAB) Voiding Diary and Urodynamics Correlation Study Recruiting NCT03473782

Search NIH Clinical Center for Bladder Neck Obstruction

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: urinary bladder neck obstruction

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Genetic Tests for Bladder Neck Obstruction

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Anatomical Context for Bladder Neck Obstruction

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MalaCards organs/tissues related to Bladder Neck Obstruction:

41
Prostate, Kidney, Skin, Liver, Heart, Testis, Placenta
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Publications for Bladder Neck Obstruction

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Articles related to Bladder Neck Obstruction:

(show top 50) (show all 168)
# Title Authors Year
1
Urodynamic outcomes of tamsulosin in the treatment of primary bladder neck obstruction in men. ( 29343910 )
2018
2
The Long-term Effect of Superficial Bladder Neck Incision on Ejaculation and Incontinence in Boys with Primary and Secondary Bladder Neck Obstruction. ( 28752084 )
2017
3
Gait analysis of young male patients diagnosed with primary bladder neck obstruction. ( 28601565 )
2017
4
Female primary bladder neck obstruction: role of videourodynamics and treatment options in a rare clinical entity. ( 27886351 )
2016
5
Controlled transurethral resection and incision of the bladder neck to treat female primary bladder neck obstruction: Description of a novel surgical procedure. ( 27037830 )
2016
6
Primary bladder neck obstruction may be determined by postural imbalances. ( 27876119 )
2016
7
Application of Acoustic Radiation Force Impulse Imaging for Diagnosis of Female Bladder Neck Obstruction. ( 27162282 )
2016
8
Use of transvaginal ultrasound in females with primary bladder neck obstruction. A preliminary study. ( 26150036 )
2015
9
Transurethral incision of the bladder neck in a woman with primary bladder neck obstruction after kidney transplantation. ( 25861513 )
2015
10
Transurethral bladder neck incision in women with primary bladder neck obstruction. ( 24496715 )
2014
11
Fetal therapy for the treatment of congenital bladder neck obstruction. ( 24934451 )
2014
12
Thulium laser resection for bladder neck obstruction in women. ( 24988202 )
2014
13
Bladder neck incision for female bladder neck obstruction: long-term outcomes. ( 24680443 )
2014
14
Video-urodynamics study on female patients with bladder neck obstruction. ( 22613647 )
2012
15
Modified transurethral incision for primary bladder neck obstruction in women: a method to improve voiding function without urinary incontinence. ( 22310746 )
2012
16
Giant Urinary Bladder and Bilateral Giant Hydronephrosis due to Bladder Neck Obstruction: One Case Report and Literature Review. ( 22606637 )
2012
17
Urodynamic differences between dysfunctional voiding and primary bladder neck obstruction in women. ( 22748864 )
2012
18
Long-term safety, tolerability, and efficacy of I+1-adrenergic blocker in young men with primary bladder neck obstruction: results from a single centre in China. ( 22130960 )
2012
19
Transurethral incision of the bladder neck using KTP in the treatment of bladder neck obstruction in women. ( 19172099 )
2009
20
Effect of alfuzosin on female primary bladder neck obstruction. ( 18982236 )
2009
21
Modified transurethral incision of the bladder neck treating primary bladder neck obstruction in young men: a method to improve voiding function and to preserve antegrade ejaculation. ( 18204229 )
2008
22
Primary bladder neck obstruction in men, women, and children. ( 17880837 )
2007
23
Primary bladder neck obstruction in men and women. ( 16985885 )
2005
24
Endoscopic incision for functional bladder neck obstruction in men: long-term outcome. ( 16040090 )
2005
25
Diagnosis and treatment of primary bladder neck obstruction in men. ( 15978226 )
2005
26
Myogenic bladder decompensation in boys with a history of posterior urethral valves is caused by secondary bladder neck obstruction? ( 15963137 )
2005
27
Use of alpha1-blockers in female functional bladder neck obstruction. ( 15812214 )
2005
28
Transurethral incision of bladder neck in treatment of bladder neck obstruction in women. ( 15708037 )
2005
29
Treatment of primary bladder neck obstruction in women with transurethral resection of the bladder neck. ( 14767294 )
2004
30
Effect of cyclohexenonic long-chain fatty alcohol on rat overactive bladder induced by bladder neck obstruction. ( 15464073 )
2004
31
Bladder neck obstruction due to bilharzial cystitis as a cause of renal failure in Aden City. ( 14612029 )
2003
32
Unilateral transurethral incision for primary bladder neck obstruction: symptom relief and fertility preservation. ( 12783172 )
2003
33
alpha1-Adrenergic blockers in young men with primary bladder neck obstruction. ( 12131312 )
2002
34
Is endoscopic decompression of the neonatal extravesical upper pole ureterocele necessary for prevention of urinary tract infections or bladder neck obstruction? ( 11832766 )
2002
35
Endoscopic treatment of complete bladder neck obstruction by transurethral Seldinger technique. ( 11555013 )
2001
36
Bladder neck obstruction in the female. ( 11998456 )
2001
37
The effectiveness of terazosin, an alpha1-blocker, on bladder neck obstruction as assessed by urodynamic hydraulic energy. ( 10671877 )
2000
38
Management of functional bladder neck obstruction in women: use of alpha-blockers and pediatric resectoscope for bladder neck incision. ( 10569570 )
1999
39
Primary bladder neck obstruction: urodynamic findings and treatment results in 36 men. ( 8808886 )
1996
40
Bladder neck obstruction caused by a large simple ureterocele in a young male. ( 7491202 )
1995
41
Laparoscopic cystomyotomy for bladder neck obstruction. ( 8845505 )
1995
42
Functional bladder neck obstruction: a rare cause of renal failure. ( 7776419 )
1995
43
Functional bladder neck obstruction in males: a progressive disorder? ( 1478227 )
1992
44
Functional bladder neck obstruction in females--a revisit. ( 1687802 )
1991
45
Effects of prazosin in men with symptoms of bladder neck obstruction and a non-hyperplastic prostate. ( 2480639 )
1989
46
Bladder neck obstruction secondary to Brunn's cyst. ( 3336077 )
1988
47
Bladder neck obstruction in women. ( 3820385 )
1987
48
Origin of carcinomas causing bladder neck obstruction demonstrated by immunoperoxidase localisation of specific antigens. ( 3521781 )
1986
49
Functional bladder neck obstruction. Results of endoscopic bladder neck incision in 131 consecutive patients. ( 3971106 )
1985
50
Bladder neck obstruction in women: a real entity. ( 6539828 )
1984
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Variations for Bladder Neck Obstruction

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Expression for Bladder Neck Obstruction

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Search GEO for disease gene expression data for Bladder Neck Obstruction.
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Pathways for Bladder Neck Obstruction

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Pathways related to Bladder Neck Obstruction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Adhesion 4
10.89 F3 KLK3 SIRPA
2
FOXA2 and FOXA3 transcription factor networks 1
10.6 AFP TTR
Sources

GO Terms for Bladder Neck Obstruction

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Cellular components related to Bladder Neck Obstruction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ACE ACPP AFP F3 KLK3 TAC1
2 extracellular region GO:0005576 9.23 ACE ACPP AFP F3 KLK3 TAC1

Biological processes related to Bladder Neck Obstruction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.13 AFP KLK3 TTR
2 neutrophil degranulation GO:0043312 8.92 ACPP SIRPA TNFRSF1B TTR
Sources

Sources for Bladder Neck Obstruction

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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