MCID: BLD046
MIFTS: 25

Bladder Papillary Transitional Cell Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Bladder Papillary Transitional Cell Neoplasm

MalaCards integrated aliases for Bladder Papillary Transitional Cell Neoplasm:

Name: Bladder Papillary Transitional Cell Neoplasm 12 15
Urinary Bladder Papillary Urothelial Neoplasm 12
Bladder Papillary Urothelial Neoplasm 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5432
NCIt 51 C39857
UMLS 74 C1511197

Summaries for Bladder Papillary Transitional Cell Neoplasm

MalaCards based summary : Bladder Papillary Transitional Cell Neoplasm, also known as urinary bladder papillary urothelial neoplasm, is related to colloid adenoma and fibroepithelial basal cell carcinoma. An important gene associated with Bladder Papillary Transitional Cell Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Pathways in cancer and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include breast, lung and skin, and related phenotypes are hematopoietic system and neoplasm

Related Diseases for Bladder Papillary Transitional Cell Neoplasm

Diseases related to Bladder Papillary Transitional Cell Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 colloid adenoma 10.2 KRT20 TP53
2 fibroepithelial basal cell carcinoma 10.2 KRT20 TP53
3 papillary serous adenocarcinoma 10.2 KRT20 TP53
4 glycogen-rich clear cell breast carcinoma 10.2 KRT20 TP53
5 biliary papillomatosis 10.2 KRT20 TP53
6 endocervical adenocarcinoma 10.2 KRT20 TP53
7 cervical adenocarcinoma 10.2 KRT20 TP53
8 eccrine sweat gland neoplasm 10.2 KRT20 TP53
9 appendix cancer 10.2 KRT20 TP53
10 cystic teratoma 10.2 KRT20 TP53
11 pseudomyxoma peritonei 10.2 KRT20 TP53
12 cervix carcinoma 10.2 FGFR3 TP53
13 ampulla of vater cancer 10.2 KRT20 TP53
14 pancreatic ductal carcinoma 10.2 KRT20 TP53
15 giant cell glioblastoma 10.2 FGFR3 TP53
16 inverted papilloma 10.2 KRT20 TP53
17 soft tissue sarcoma 10.2 TERT TP53
18 cystitis cystica 10.2 KRT20 TERT
19 jejunal adenocarcinoma 10.2 KRT20 MSH6
20 dyskeratosis congenita autosomal recessive 10.2 TERT TP53
21 actinic keratosis 10.2 KRT20 TP53
22 cecum adenocarcinoma 10.1 KRT20 MSH6
23 small cell carcinoma 10.1 KRT20 TP53
24 sweat gland cancer 10.1 KRT20 TP53
25 skin benign neoplasm 10.1 KRT20 MSH6
26 supratentorial cancer 10.1 TERT TP53
27 small intestine cancer 10.1 KRT20 MSH6
28 cerebrum cancer 10.1 TERT TP53
29 merkel cell carcinoma 10.1 KRT20 TP53
30 transitional cell carcinoma 10.0 FGFR3 KRT20 TP53
31 papilloma 10.0 FGFR3 KRT20 TP53
32 bladder urothelial carcinoma 10.0 FGFR3 KRT20 TP53
33 uterine anomalies 10.0 MSH6 TP53
34 laryngeal squamous cell carcinoma 10.0 TERT TP53
35 colonic disease 10.0 MSH6 TP53
36 cholangiocarcinoma 10.0 KRT20 TERT TP53
37 colorectal adenocarcinoma 9.9 KRT20 MSH6 TP53
38 hereditary breast ovarian cancer syndrome 9.9 MSH6 TP53
39 female reproductive system disease 9.9 MSH6 TP53
40 brain cancer 9.8 MSH6 TERT TP53
41 non-invasive bladder papillary urothelial neoplasm 9.8 FGFR3 SIGLEC12 TP53
42 bladder disease 9.8 FGFR3 KRT20 TERT TP53
43 lung cancer susceptibility 3 9.8 FGFR3 KRT20 TERT TP53
44 bladder cancer 9.8 FGFR3 KRT20 TERT TP53
45 large intestine cancer 9.7 KRT20 MSH6 TERT TP53
46 cervical cancer 9.6 FGFR3 TERT TP53
47 urinary tract papillary transitional cell benign neoplasm 9.1 FGFR3 KRT20 LMAN1 PTGES2 TERT TP53

Graphical network of the top 20 diseases related to Bladder Papillary Transitional Cell Neoplasm:



Diseases related to Bladder Papillary Transitional Cell Neoplasm

Symptoms & Phenotypes for Bladder Papillary Transitional Cell Neoplasm

MGI Mouse Phenotypes related to Bladder Papillary Transitional Cell Neoplasm:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.43 FGFR3 LMAN1 MSH6 PTGES2 TERT TP53
2 neoplasm MP:0002006 8.92 FGFR3 MSH6 TERT TP53

Drugs & Therapeutics for Bladder Papillary Transitional Cell Neoplasm

Search Clinical Trials , NIH Clinical Center for Bladder Papillary Transitional Cell Neoplasm

Genetic Tests for Bladder Papillary Transitional Cell Neoplasm

Anatomical Context for Bladder Papillary Transitional Cell Neoplasm

MalaCards organs/tissues related to Bladder Papillary Transitional Cell Neoplasm:

42
Breast, Lung, Skin, Brain, Colon, Cervix, Small Intestine

Publications for Bladder Papillary Transitional Cell Neoplasm

Variations for Bladder Papillary Transitional Cell Neoplasm

Cosmic variations for Bladder Papillary Transitional Cell Neoplasm:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM483 HRAS urinary tract,bladder,other,neoplasm c.35G>T p.G12V 11:534288-534288 0
2 COSM499 HRAS urinary tract,bladder,other,neoplasm c.182A>G p.Q61R 11:533874-533874 0
3 COSM498 HRAS urinary tract,bladder,other,neoplasm c.182A>T p.Q61L 11:533874-533874 0
4 COSM496 HRAS urinary tract,bladder,other,neoplasm c.181C>A p.Q61K 11:533875-533875 0
5 COSM488 HRAS urinary tract,bladder,other,neoplasm c.37G>T p.G13C 11:534286-534286 0

Expression for Bladder Papillary Transitional Cell Neoplasm

Search GEO for disease gene expression data for Bladder Papillary Transitional Cell Neoplasm.

Pathways for Bladder Papillary Transitional Cell Neoplasm

Pathways related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.65 FGFR3 MSH6 TERT TP53
2
Show member pathways
11.54 FGFR3 TERT TP53
3 11.23 FGFR3 TP53
4 11.18 MSH6 TP53
5 11.07 FGFR3 TP53
6 10.62 MSH6 TP53

GO Terms for Bladder Papillary Transitional Cell Neoplasm

Biological processes related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway GO:0097193 9.26 MSH6 TP53
2 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 TERT TP53
3 determination of adult lifespan GO:0008340 8.96 MSH6 TP53
4 replicative senescence GO:0090399 8.62 TERT TP53

Sources for Bladder Papillary Transitional Cell Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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