MCID: BLD046
MIFTS: 21

Bladder Papillary Transitional Cell Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Bladder Papillary Transitional Cell Neoplasm

MalaCards integrated aliases for Bladder Papillary Transitional Cell Neoplasm:

Name: Bladder Papillary Transitional Cell Neoplasm 12 15
Urinary Bladder Papillary Urothelial Neoplasm 12
Bladder Papillary Urothelial Neoplasm 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5432
NCIt 50 C39857
UMLS 70 C1511197

Summaries for Bladder Papillary Transitional Cell Neoplasm

MalaCards based summary : Bladder Papillary Transitional Cell Neoplasm, also known as urinary bladder papillary urothelial neoplasm, is related to actinic cheilitis and cheilitis. An important gene associated with Bladder Papillary Transitional Cell Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways is Bladder cancer. Affiliated tissues include lung, thyroid and appendix.

Related Diseases for Bladder Papillary Transitional Cell Neoplasm

Diseases related to Bladder Papillary Transitional Cell Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 actinic cheilitis 10.3 TP53 FGFR3
2 cheilitis 10.3 TP53 FGFR3
3 intratubular embryonal carcinoma 10.3 TP53 KRT20
4 eccrine sweat gland cancer 10.3 TP53 KRT20
5 sweat gland cancer 10.3 TP53 KRT20
6 clear cell basal cell carcinoma 10.3 TP53 KRT20
7 urethral benign neoplasm 10.3 TP53 KRT20
8 appendix disease 10.3 TP53 KRT20
9 peritoneal serous adenocarcinoma 10.3 TP53 KRT20
10 human papillomavirus infectious disease 10.3 TP53 TERT
11 appendix cancer 10.3 TP53 KRT20
12 bile duct adenoma 10.3 TP53 KRT20
13 thyroid angiosarcoma 10.3 TERT KRT20
14 ovarian benign neoplasm 10.3 TP53 KRT20
15 intrahepatic bile duct adenoma 10.3 TP53 KRT20
16 urethra transitional cell carcinoma 10.3 UPK3A TP53
17 acanthoma 10.3 TP53 FGFR3
18 granulosa cell tumor of the ovary 10.3 TP53 TERT
19 mixed oligodendroglioma-astrocytoma 10.3 TP53 TERT
20 vulva adenocarcinoma 10.3 UPK3A KRT20
21 borst-jadassohn intraepidermal carcinoma 10.3 TP53 KRT20
22 ovarian brenner tumor 10.2 UPK3A KRT20
23 invasive bladder transitional cell carcinoma 10.2 UPK3A TP53
24 dyskeratosis congenita autosomal recessive 10.2 TP53 TERT
25 duodenum cancer 10.2 TP53 KRT20
26 urethra clear cell adenocarcinoma 10.2 UPK3A KRT20
27 liver benign neoplasm 10.2 TP53 TERT
28 bladder adenocarcinoma 10.2 UPK3A KRT20
29 renal hypodysplasia/aplasia 3 10.2 UPK3A FGFR3
30 ureter, cancer of 10.2 TERT FGFR3
31 chronic cystitis 10.2 UPK3A KRT20
32 papillary serous adenocarcinoma 10.2 TP53 KRT20
33 papilloma 10.2 TP53 KRT20 FGFR3
34 bladder sarcoma 10.2 UPK3A KRT20
35 basaloid squamous cell carcinoma 10.2 TP53 KRT20
36 pseudomyxoma peritonei 10.2 TP53 KRT20
37 chronic cervicitis 10.2 ZKSCAN3 TP53
38 teratoma 10.2 TP53 KRT20 FGFR3
39 villous adenoma 10.2 TP53 KRT20
40 inverted papilloma 10.1 TP53 KRT20
41 lung benign neoplasm 10.1 TP53 TERT KRT20
42 t-cell adult acute lymphocytic leukemia 10.1 TP53 CNTN2
43 colorectal adenocarcinoma 10.1 TP53 TERT KRT20
44 signet ring cell adenocarcinoma 10.1 TP53 KRT20
45 ureteral benign neoplasm 10.1 ZKSCAN3 UPK3A
46 glandular cystitis 10.1 UPK3A TP53 KRT20
47 progressive pseudorheumatoid dysplasia 10.1 CCN6 CCN1
48 cystitis 10.1 UPK3A TP53 KRT20
49 bladder clear cell adenocarcinoma 10.1 UPK3A TP53 KRT20
50 gliosarcoma 10.1 TP53 TERT FGFR3

Graphical network of the top 20 diseases related to Bladder Papillary Transitional Cell Neoplasm:



Diseases related to Bladder Papillary Transitional Cell Neoplasm

Symptoms & Phenotypes for Bladder Papillary Transitional Cell Neoplasm

Drugs & Therapeutics for Bladder Papillary Transitional Cell Neoplasm

Search Clinical Trials , NIH Clinical Center for Bladder Papillary Transitional Cell Neoplasm

Genetic Tests for Bladder Papillary Transitional Cell Neoplasm

Anatomical Context for Bladder Papillary Transitional Cell Neoplasm

MalaCards organs/tissues related to Bladder Papillary Transitional Cell Neoplasm:

40
Lung, Thyroid, Appendix, Liver, Ovary

Publications for Bladder Papillary Transitional Cell Neoplasm

Articles related to Bladder Papillary Transitional Cell Neoplasm:

# Title Authors PMID Year
1
Bladder papillary urothelial neoplasm of low malignant potential in Chinese: a clinical and pathological analysis. 61
26191263 2015

Variations for Bladder Papillary Transitional Cell Neoplasm

Expression for Bladder Papillary Transitional Cell Neoplasm

Search GEO for disease gene expression data for Bladder Papillary Transitional Cell Neoplasm.

Pathways for Bladder Papillary Transitional Cell Neoplasm

Pathways related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.66 UPK3A TP53 FGFR3

GO Terms for Bladder Papillary Transitional Cell Neoplasm

Cellular components related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 8.92 CCN6 CCN5 CCN4 CCN1

Biological processes related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of mitotic cell cycle GO:0045930 9.46 TP53 BRINP1
2 cell-cell signaling GO:0007267 9.46 FGFR3 CCN6 CCN5 CCN4
3 positive regulation of Wnt signaling pathway GO:0030177 9.43 TERT CCN4
4 cell adhesion GO:0007155 9.43 SIGLEC12 CNTN2 CCN6 CCN5 CCN4 CCN1
5 negative regulation of cellular senescence GO:2000773 9.4 ZKSCAN3 TERT
6 replicative senescence GO:0090399 9.37 TP53 TERT
7 negative regulation of production of miRNAs involved in gene silencing by miRNA GO:1903799 9.32 TP53 TERT
8 positive regulation of phospholipase activity GO:0010518 9.26 FGFR3 CCN1
9 negative regulation of cell death GO:0060548 8.92 CCN6 CCN5 CCN4 CCN1

Molecular functions related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 9.46 CCN6 CCN5 CCN4 CCN1
2 integrin binding GO:0005178 9.26 CCN6 CCN5 CCN4 CCN1
3 insulin-like growth factor binding GO:0005520 8.92 CCN6 CCN5 CCN4 CCN1

Sources for Bladder Papillary Transitional Cell Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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