MCID: BLD046
MIFTS: 23

Bladder Papillary Transitional Cell Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Bladder Papillary Transitional Cell Neoplasm

MalaCards integrated aliases for Bladder Papillary Transitional Cell Neoplasm:

Name: Bladder Papillary Transitional Cell Neoplasm 12 15
Urinary Bladder Papillary Urothelial Neoplasm 12
Bladder Papillary Urothelial Neoplasm 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5432
NCIt 50 C39857
UMLS 73 C1511197

Summaries for Bladder Papillary Transitional Cell Neoplasm

MalaCards based summary : Bladder Papillary Transitional Cell Neoplasm, also known as urinary bladder papillary urothelial neoplasm, is related to papillary transitional carcinoma and vulval paget's disease. An important gene associated with Bladder Papillary Transitional Cell Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Bladder cancer and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include lung, breast and ovary, and related phenotype is hematopoietic system.

Related Diseases for Bladder Papillary Transitional Cell Neoplasm

Diseases related to Bladder Papillary Transitional Cell Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 papillary transitional carcinoma 10.2 KRT20 PTCRA
2 vulval paget's disease 10.2 KRT20 PTCRA
3 actinic cheilitis 10.2 FGFR3 TP53
4 vulva adenocarcinoma 10.2 KRT20 PTCRA
5 colloid adenoma 10.1 KRT20 TP53
6 fibroepithelial basal cell carcinoma 10.1 KRT20 TP53
7 papillary serous adenocarcinoma 10.1 KRT20 TP53
8 glycogen-rich clear cell breast carcinoma 10.1 KRT20 TP53
9 cervix carcinoma 10.1 FGFR3 TP53
10 biliary papillomatosis 10.1 KRT20 TP53
11 endocervical adenocarcinoma 10.1 KRT20 TP53
12 cervical adenocarcinoma 10.1 KRT20 TP53
13 eccrine sweat gland neoplasm 10.1 KRT20 TP53
14 giant cell glioblastoma 10.1 FGFR3 TP53
15 appendix cancer 10.1 KRT20 TP53
16 cystic teratoma 10.1 KRT20 TP53
17 pseudomyxoma peritonei 10.1 KRT20 TP53
18 ampulla of vater cancer 10.1 KRT20 TP53
19 pancreatic ductal carcinoma 10.1 KRT20 TP53
20 inverted papilloma 10.1 KRT20 TP53
21 actinic keratosis 10.1 KRT20 TP53
22 factor v deficiency 10.1 LMAN1 PTCRA
23 small cell carcinoma 10.1 KRT20 TP53
24 sweat gland cancer 10.1 KRT20 TP53
25 merkel cell carcinoma 10.1 KRT20 TP53
26 scrotal carcinoma 10.0 ANO2 TP53
27 colorectal adenocarcinoma 10.0 KRT20 TP53
28 non-invasive bladder papillary urothelial neoplasm 10.0 FGFR3 PTCRA TP53
29 rectal neoplasm 10.0 KRT20 TP53
30 transitional cell carcinoma 10.0 FGFR3 KRT20 TP53
31 papilloma 10.0 FGFR3 KRT20 TP53
32 bladder urothelial carcinoma 10.0 FGFR3 KRT20 TP53
33 ureter, cancer of 10.0 PTCRA TERT
34 intrahepatic cholangiocarcinoma 10.0 KRT20 TP53
35 cystitis cystica 10.0 KRT20 TERT
36 soft tissue sarcoma 10.0 TERT TP53
37 testicular germ cell tumor 10.0 FGFR3 TP53
38 dyskeratosis congenita autosomal recessive 10.0 TERT TP53
39 supratentorial cancer 9.9 TERT TP53
40 cerebrum cancer 9.9 TERT TP53
41 anaplastic thyroid cancer 9.9 TERT TP53
42 laryngeal squamous cell carcinoma 9.9 TERT TP53
43 gliosarcoma 9.9 FGFR3 TP53
44 respiratory system cancer 9.8 TERT TP53
45 cholangiocarcinoma 9.8 KRT20 TERT TP53
46 large intestine cancer 9.8 KRT20 TERT TP53
47 cervical cancer 9.7 FGFR3 TERT TP53
48 lung cancer susceptibility 3 9.7 FGFR3 KRT20 TERT TP53
49 bladder cancer 9.7 FGFR3 KRT20 TERT TP53
50 bladder disease 9.6 FGFR3 KRT20 PTCRA TERT TP53

Graphical network of the top 20 diseases related to Bladder Papillary Transitional Cell Neoplasm:



Diseases related to Bladder Papillary Transitional Cell Neoplasm

Symptoms & Phenotypes for Bladder Papillary Transitional Cell Neoplasm

MGI Mouse Phenotypes related to Bladder Papillary Transitional Cell Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.1 FGFR3 LMAN1 PTCRA PTGES2 TERT TP53

Drugs & Therapeutics for Bladder Papillary Transitional Cell Neoplasm

Search Clinical Trials , NIH Clinical Center for Bladder Papillary Transitional Cell Neoplasm

Genetic Tests for Bladder Papillary Transitional Cell Neoplasm

Anatomical Context for Bladder Papillary Transitional Cell Neoplasm

MalaCards organs/tissues related to Bladder Papillary Transitional Cell Neoplasm:

41
Lung, Breast, Ovary, Cervix, Thyroid, Appendix

Publications for Bladder Papillary Transitional Cell Neoplasm

Variations for Bladder Papillary Transitional Cell Neoplasm

Cosmic variations for Bladder Papillary Transitional Cell Neoplasm:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM483 HRAS urinary tract,bladder,other,neoplasm c.35G>T p.G12V 11:534288-534288 8
2 COSM499 HRAS urinary tract,bladder,other,neoplasm c.182A>G p.Q61R 11:533874-533874 8
3 COSM498 HRAS urinary tract,bladder,other,neoplasm c.182A>T p.Q61L 11:533874-533874 8
4 COSM496 HRAS urinary tract,bladder,other,neoplasm c.181C>A p.Q61K 11:533875-533875 8
5 COSM488 HRAS urinary tract,bladder,other,neoplasm c.37G>T p.G13C 11:534286-534286 8

Expression for Bladder Papillary Transitional Cell Neoplasm

Search GEO for disease gene expression data for Bladder Papillary Transitional Cell Neoplasm.

Pathways for Bladder Papillary Transitional Cell Neoplasm

Pathways related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.02 FGFR3 TP53
2
Show member pathways
11.01 FGFR3 TERT TP53
3 10.77 FGFR3 TP53

GO Terms for Bladder Papillary Transitional Cell Neoplasm

Biological processes related to Bladder Papillary Transitional Cell Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 8.96 TERT TP53
2 replicative senescence GO:0090399 8.62 TERT TP53

Sources for Bladder Papillary Transitional Cell Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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