MCID: BLD025
MIFTS: 29

Bladder Sarcoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Bladder Sarcoma

MalaCards integrated aliases for Bladder Sarcoma:

Name: Bladder Sarcoma 12 15 71
Sarcoma of the Urinary Bladder 12
Sarcoma of Bladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11812
NCIt 49 C4669
UMLS 71 C0349666

Summaries for Bladder Sarcoma

Disease Ontology : 12 A sarcoma and malignant neoplasm of urinary bladder that is located in the bladder.

MalaCards based summary : Bladder Sarcoma, also known as sarcoma of the urinary bladder, is related to leiomyosarcoma and sarcoma. An important gene associated with Bladder Sarcoma is MYOG (Myogenin), and among its related pathways/superpathways are Cytochrome P450 - arranged by substrate type and Folate Metabolism. Affiliated tissues include bladder, myeloid and prostate, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Bladder Sarcoma

Graphical network of the top 20 diseases related to Bladder Sarcoma:



Diseases related to Bladder Sarcoma

Symptoms & Phenotypes for Bladder Sarcoma

GenomeRNAi Phenotypes related to Bladder Sarcoma according to GeneCards Suite gene sharing:

26 (showing 11, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.62 GGTLC1 GGTLC2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.62 GGTLC1 GGTLC2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.62 GGTLC1 GGTLC2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-200 9.62 GGTLC1 GGTLC2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.62 GGTLC2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.62 GGTLC2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-130 9.5 GGTLC2
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-156 9.5 GGTLC1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.5 GGTLC2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.5 GGTLC1 GGTLC2
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-62 9.5 GGTLC1 GGTLC2

Drugs & Therapeutics for Bladder Sarcoma

Search Clinical Trials , NIH Clinical Center for Bladder Sarcoma

Genetic Tests for Bladder Sarcoma

Anatomical Context for Bladder Sarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Bladder Sarcoma:

19
Bladder

MalaCards organs/tissues related to Bladder Sarcoma:

40
Myeloid, Prostate, Lymph Node, Heart, Kidney

Publications for Bladder Sarcoma

Articles related to Bladder Sarcoma:

(showing 61, show less)
# Title Authors PMID Year
1
Carcino-sarcoma of the urinary bladder with cartilaginous differentiation: About a case report. 61
31681537 2020
2
Primary follicular dendritic cell sarcoma of the urinary bladder: the first case report and potential diagnostic pitfalls. 61
28438212 2017
3
Lymph node metastases in patients with urothelial carcinoma variants: influence of the specific variant on nodal histology. 61
25047418 2015
4
Multiple groups of endogenous epsilon-like retroviruses conserved across primates. 61
25142585 2014
5
Leiomyosarcoma, a nonurothelial bladder tumor: a rare entity with therapeutic diversity. 61
23789052 2013
6
Granulocytic sarcoma of the urinary bladder in a pediatric patient. 61
22583597 2013
7
Commentary to 'Granulocytic sarcoma of the urinary bladder in a pediatric patient'. 61
22763104 2013
8
Histiocytic sarcoma of the urinary bladder in a dog. 61
22136452 2011
9
Cutaneous metastasis of bladder sarcoma: when should we consider this hypothesis? A review of the literature. 61
22147049 2011
10
Primitive neuroectodermal tumor/Ewing's sarcoma of the urinary bladder: a case report and its molecular diagnosis. 61
21063743 2011
11
Myeloid sarcoma of the urinary bladder with cutaneous tumour seeding after percutaneous suprapubic catheterization. 61
21874752 2011
12
[Case report: a patient with bladder sarcoma exclusively treated with transurethral resection with long-term follow-up]. 61
19663245 2009
13
Pseudosarcomatous and sarcomatous proliferations of the bladder. 61
17306332 2007
14
Review of the M.D. Anderson experience in the treatment of bladder sarcoma. 61
17208137 2007
15
Alveolar soft-part sarcoma of the urinary bladder with urethral recurrence: a unique case with emphasis on differential diagnoses and diagnostic utility of an immunohistochemical panel including TFE3. 61
17001165 2006
16
Myeloid sarcoma of the urinary bladder and epididymis as a primary manifestation of acute myeloid leukemia with inv(16). 61
16740041 2006
17
Identification and characterization of an exogenous retrovirus from atlantic salmon swim bladder sarcomas. 61
16501103 2006
18
Granulocytic sarcoma of the urinary bladder. 61
15054826 2004
19
First cases of animal diseases published since 2000. 1. Dogs. 61
14535581 2003
20
Neurovesical dysfunction in children after treating pelvic neoplasms. 61
12887486 2003
21
Primary granulocytic sarcoma of the urinary bladder: case report and review of the literature. 61
12137850 2002
22
[Multiple synchronous primary malignant tumors of fibrosarcoma and squamous cell carcinoma in the urinary bladder: a case report]. 61
12174642 2002
23
Rhabdomyosarcoma (botryoid sarcoma) of the urinary bladder in a Maltese. 61
12074293 2002
24
[Leiomyosarcoma of the bladder. Report of a new case and review of the literature]. 61
10394658 1999
25
Multifocal Sarcoma of the Urinary Bladder. 61
10851299 1999
26
Primary osteogenic sarcoma of the urinary bladder successfully treated with combination therapy. 61
7974956 1994
27
[Leukemoid reaction and thrombocytosis in bladder sarcoma]. 61
7942222 1994
28
[Bladder tumors in patients under 40 years of age]. 61
7825985 1994
29
[Kaposi's sarcoma of the urinary bladder after kidney transplantation]. 61
1464548 1992
30
[Two case reports of eosinophilic cystitis--clinical review of 43 cases in Japan]. 61
1942710 1991
31
[Indiana continent urinary reservoir: report of 15 cases]. 61
2801378 1989
32
Schistosomiasis and sarcoma of the urinary bladder. 61
3145885 1988
33
Pharmacokinetics of "activated" cyclophosphamide and therapeutic efficacies. 61
6467149 1984
34
[Treatment of five cases of bladder sarcoma]. 61
6516999 1984
35
[Chordoid sarcoma of the urinary bladder]. 61
6524124 1984
36
Hematologic neoplasms with initial manifestations in lower urinary tract. 61
6581644 1984
37
The influence of the protector thiol L-cystein on the toxic and therapeutic responses of stabilized "activated" cyclophosphamide (4-(S-ethanol)-sulfido-cyclophosphamide). 61
6469518 1984
38
Sarcoma of the urinary bladder in the adult. Pathomorphological considerations. 61
160989 1979
39
Sarcoma of the urinary bladder and prostate in children. 61
738298 1978
40
[Bladder sarcoma in adults]. 61
1274362 1976
41
Embryonal rhabdomyosarcoma of the bladder and prostate in childhood. 61
1127815 1975
42
[Electron microscopy demonstration of the myoblastic origin of various tumours]. 61
50146 1975
43
[Sarcoma of the urinary bladder (author's transl)]. 61
4589194 1973
44
Primary osteogenic sarcoma of the urinary bladder. 61
4518929 1973
45
[Sarcoma of the urinary bladder in childhood]. 61
5423181 1970
46
[Botryoid sarcoma of the urinary bladder in a 3 and a half-year-old boy]. 61
5805032 1969
47
Bladder sarcoma. The presentation of three cases. 61
5308760 1968
48
[Case of primary osteoplastic sarcoma of the urinary bladder]. 61
4174066 1967
49
An autopsy case of primary osteogenic sarcoma of the urinary bladder. 61
5217046 1965
50
[Sarcoma of the urinary bladder]. 61
13887893 1962
51
[Sarcoma of the urinary bladder and prostate in children]. 61
14451149 1961
52
[2 cases of botryoid sarcoma of the urinary bladder in infants]. 61
14480099 1961
53
Bladder sarcoma. 61
13838071 1959
54
[Bladder sarcoma in a child]. 61
13531656 1957
55
A case of sarcoma of the urinary bladder in von Recklinghausen's disease. 61
13436762 1957
56
Primary osteogenic sarcoma of the urinary bladder. 61
13567658 1956
57
Polypoid rhabdomyosarcoma of the bladder: sarcoma botryoides. 61
14369935 1955
58
[Rhabdomyoblastic sarcoma of the urinary bladder in children]. 61
13116173 1953
59
[Notes on sarcoma of the urinary bladder]. 61
13112478 1953
60
Sarcoma of the urinary bladder in children; with a review of the literature. 61
15396496 1949
61
Primary spindle cell sarcoma of the urinary bladder with solitary metastasis to the heart muscle. 61
20990742 1946

Variations for Bladder Sarcoma

Expression for Bladder Sarcoma

Search GEO for disease gene expression data for Bladder Sarcoma.

Pathways for Bladder Sarcoma

Pathways related to Bladder Sarcoma according to GeneCards Suite gene sharing:

(showing 7, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.58 GGTLC2 GGT7 GGT6
2
Show member pathways
11.7 GGTLC2 GGTLC1
3
Show member pathways
11.56 GGTLC2 GGTLC1 GGT7 GGT6
4 11.48 GGTLC2 GGTLC1
5 10.64 GGTLC2 GGTLC1
6 10.2 GGT7 GGT6
7 10.16 GGTLC2 GGT7 GGT6

GO Terms for Bladder Sarcoma

Biological processes related to Bladder Sarcoma according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.56 GGTLC2 GGTLC1 GGT7 GGT6
2 biological_process GO:0008150 9.54 GGTLC2 GGTLC1 GGT6
3 glutathione metabolic process GO:0006749 9.32 GGT7 GGT6
4 glutathione biosynthetic process GO:0006750 9.16 GGT7 GGT6
5 glutathione catabolic process GO:0006751 9.13 GGTLC2 GGTLC1 GGT7
6 leukotriene D4 biosynthetic process GO:1901750 8.92 GGTLC2 GGTLC1 GGT7 GGT6

Molecular functions related to Bladder Sarcoma according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 molecular_function GO:0003674 9.43 GGTLC2 GGTLC1 GGT6
2 transferase activity, transferring acyl groups GO:0016746 9.32 GGT7 GGT6
3 leukotriene C4 gamma-glutamyl transferase activity GO:0103068 9.16 GGT7 GGT6
4 hypoglycin A gamma-glutamyl transpeptidase activity GO:0102953 8.96 GGT7 GGT6
5 glutathione hydrolase activity GO:0036374 8.92 GGTLC2 GGTLC1 GGT7 GGT6

Sources for Bladder Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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