MCID: BLN006
MIFTS: 29

Blind Loop Syndrome

Categories: Gastrointestinal diseases

Aliases & Classifications for Blind Loop Syndrome

MalaCards integrated aliases for Blind Loop Syndrome:

Name: Blind Loop Syndrome 12 44 15 73
Bacterial Overgrowth Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10606
ICD10 33 K90.2
ICD9CM 35 579.2
MeSH 44 D001765
NCIt 50 C34431
SNOMED-CT 68 66379009 77225009
UMLS 73 C0005750

Summaries for Blind Loop Syndrome

Disease Ontology : 12 An intestinal disease characterized by a dysbalance of the bacterial flora of the small intestine, causing derangement to the normal physiological processes of digestion and absorption.

MalaCards based summary : Blind Loop Syndrome, also known as bacterial overgrowth syndrome, is related to duodenal atresia and mucositis. An important gene associated with Blind Loop Syndrome is GIF (Gastric Intrinsic Factor). The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include small intestine, heart and testes.

Wikipedia : 76 Blind loop syndrome (BLS) is a state that occurs when the normal bacterial flora of the small intestine... more...

Related Diseases for Blind Loop Syndrome

Diseases related to Blind Loop Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 duodenal atresia 11.0
2 mucositis 9.9
3 arthritis 9.8
4 steatorrhea 9.8
5 tropical sprue 9.8
6 duodenal obstruction 9.8
7 duodenitis 9.8
8 gastroparesis 9.7
9 constipation 9.7
10 neuropathy 9.7
11 muscular dystrophy 9.7
12 osteomalacia 9.6
13 protein-losing enteropathy 9.6
14 megaesophagus 9.6
15 megaloblastic anemia 9.6
16 panniculitis 9.6
17 dermatitis 9.6
18 reactive arthritis 9.6
19 cholangitis 9.6
20 spinocerebellar degeneration 9.6

Comorbidity relations with Blind Loop Syndrome via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Blind Loop Syndrome:



Diseases related to Blind Loop Syndrome

Symptoms & Phenotypes for Blind Loop Syndrome

Drugs & Therapeutics for Blind Loop Syndrome

Drugs for Blind Loop Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Not Applicable 50-78-2 2244
2
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
3
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
4
Pravastatin Approved Phase 4 81093-37-0 54687
5 Analgesics Phase 4
6 Analgesics, Non-Narcotic Phase 4
7 Anti-Inflammatory Agents Phase 4,Not Applicable
8 Anti-Inflammatory Agents, Non-Steroidal Phase 4
9 Antipyretics Phase 4
10 Antirheumatic Agents Phase 4
11 Cyclooxygenase Inhibitors Phase 4
12 Fibrinolytic Agents Phase 4
13 Peripheral Nervous System Agents Phase 4
14 Platelet Aggregation Inhibitors Phase 4
15 Anticholesteremic Agents Phase 4
16 Antimetabolites Phase 4
17 Atorvastatin Calcium Phase 4 134523-03-8
18 Calcium, Dietary Phase 4
19 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
20 Hypolipidemic Agents Phase 4
21 Lipid Regulating Agents Phase 4
22 Chinese Salvia Nutraceutical Phase 4,Not Applicable
23
Ginseng Approved, Investigational, Nutraceutical Phase 2,Not Applicable 50647-08-0
24
Erythromycin Approved, Investigational, Vet_approved Not Applicable 114-07-8 12560
25
Neomycin Approved, Vet_approved Not Applicable 1404-04-2 8378
26 Tangerine Approved, Nutraceutical Not Applicable
27 Anti-Bacterial Agents Not Applicable
28 Anti-Infective Agents Not Applicable
29 Erythromycin Estolate Not Applicable
30 Erythromycin Ethylsuccinate Not Applicable
31 Erythromycin stearate Not Applicable
32 Gastrointestinal Agents Not Applicable
33 Liver Extracts Not Applicable
34 Antibiotics, Antitubercular
35 Angelica Nutraceutical Not Applicable
36 Astragalus Nutraceutical Not Applicable
37 Dong Quai Nutraceutical Not Applicable

Interventional clinical trials:

(show all 30)
# Name Status NCT ID Phase Drugs
1 The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients Unknown status NCT02850627 Phase 4 Tongguan capsule;placebo capsule
2 Effectiveness and Safety of Yiqitongluo Granule for Stroke Unknown status NCT02604654 Phase 4 Yiqitongluo granule
3 Clinical Study of Combination Therapy for Angina of Coronary Heart Disease With Aspirin and Salvianolate Injection Unknown status NCT02694848 Phase 4 Salvianolate injection;Aspirin
4 Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke Completed NCT01762163 Phase 4 Qizhitongluo Capsule;Naoxintong Capsule;Aspirin Enteric-coated Tablets;placebo
5 Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index Completed NCT01502943 Phase 4 Louxiangdan Tongxin granules;TCM granules placebo;Chixiangshen Tongxin granules;TCM granule placebo plus western basis treatment;Western basis treatment
6 Danhong Injection in the Treatment of Acute Ischemic Stroke Recruiting NCT01677208 Phase 4 Danhong injection;placebo
7 The Study of MicroRNA Genomics of Blood Stasis Syndrome and of Coronary Heart Disease Unknown status NCT01615003 Phase 2 Xuesaitong soft capsule;Xuesaitong soft capsule Placebo
8 Multicentre, Randomized, Controlled Trial of Qideng Mingmu Capsule in The Treatment of Diabetic Retinopathy Completed NCT01373476 Phase 2 Qideng Mingmu capsule;Placebo Comparator
9 Observing the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy Completed NCT02303665 Phase 2
10 The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2 xue-fu-zhu-yu capsule;xue-fu-zhu-yu capsule simulated agent
11 Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina Recruiting NCT03083119 Phase 2 Xuesaitong soft capsule;Placebo oral capsule
12 A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome) Recruiting NCT02875639 Phase 2 Yiqi prescription;Huoxue prescription;Buyang huanwu decoction;QISHEN YIQI DRIPPING PILLS;Placebo 1;Placebo 2
13 Observation on the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy Recruiting NCT03078205 Phase 2
14 Uncut Roux-en-Y Gastrojejunostomy for Early Gastric Cancer Patients Recruiting NCT02644148 Phase 2
15 Clinical Evaluation and Generalized Application of "Qing-Hua-Bu" Three Dynamic Sequential Therapy of Diabetic Ulcer Not yet recruiting NCT03574935 Phase 2 External Chinese medicine;External Western medicine
16 Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy Unknown status NCT01097811 Not Applicable Erythromycin;Neomycin
17 Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing Completed NCT01324895
18 Dynamic Combination Therapy on Chinese Herbal Granules to Improve the Symptoms in Convalescent Phase of Ischemic Stroke Completed NCT01780480 Not Applicable Dynamic Chinese herbal granule formula;Placebo
19 Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS) Completed NCT00858130 Not Applicable
20 Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations Completed NCT01636154 Not Applicable Ixeris of sonchifolia Hance;Panax notoginseng saponins;Ixeris of sonchifolia Hance combined with Panax notoginseng saponins
21 Screening Protein Markers in Patients With Rheumatoid Arthritis and Hot-dampness and Blood Stasis Syndrome Recruiting NCT02408094
22 Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome Recruiting NCT02967718
23 Small Intestinal Bacterial Overgrowth Obese Recruiting NCT02819037 Not Applicable
24 Uncut Roux-en-Y vs Roux-en-Y Recruiting NCT03349398 Not Applicable
25 Yiqi Huoxue Demolition and Recipes on Recovery Stage of Cerebral Infarction Recruiting NCT02846207 Not Applicable Yiqi huoxue;Yiqi group;Huoxue group;placebo
26 Clinical Study On The Relation Among Prescription, Syndrome and Disease of Turbid Phlegm and Blood Stasis for Coronary Heart Disease Recruiting NCT02526381 Not Applicable Danlou Tablets;Tongmai Yangxin Pills
27 Heat-clearing and Blood-activating Chinese Medicinal Components in Acute Cerebral Infarction Recruiting NCT02544087 Not Applicable Ixeris of sonchifolia Hance;Panax notoginseng saponins;Ixeris of sonchifolia Hance combined with Panax notoginseng saponins
28 Impact of Traditional Chinese Medicine on the Gut Microbiota-dependent Trimethylamine N-oxide Recruiting NCT03186625 Not Applicable Compound Panax Notoginseng Granule;Placebo Granule
29 Clinical Study on Treatment of Postmenopausal Osteoporosis (Kidney Deficiency and Blood Stasis Syndrome) With Xulin Jiangu Granules Not yet recruiting NCT03563235 Early Phase 1 Xulin Jiangu granules;Calcitriol capsules
30 Clinical Trial of PSORI-CM01(YXBCM01) Granule to Treat Stable Plaque Psoriasis Terminated NCT02153840 Not Applicable PSORI-CM01(YXBCM01) granule;placebo

Search NIH Clinical Center for Blind Loop Syndrome

Cochrane evidence based reviews: blind loop syndrome

Genetic Tests for Blind Loop Syndrome

Anatomical Context for Blind Loop Syndrome

MalaCards organs/tissues related to Blind Loop Syndrome:

41
Small Intestine, Heart, Testes, Kidney, Liver

Publications for Blind Loop Syndrome

Articles related to Blind Loop Syndrome:

(show top 50) (show all 77)
# Title Authors Year
1
A Case of Blind Loop Syndrome Caused by Infection with Giardia duodenalis Diagnosed with Double Balloon Enteroscopy. ( 25408630 )
2014
2
Migrating motor complex changes after side-to-side ileal bypass in mouse ileum ex-vivo: mechanism underlying the blind loop syndrome? ( 22066044 )
2011
3
Reversible acute reactive arthritis secondary to iatrogenic blind loop syndrome. ( 17925936 )
2007
4
Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome. ( 15813834 )
2005
5
Blind loop syndrome after biliopancreatic diversion: a diagnostic challenge. ( 11594112 )
2001
6
Blind loop syndrome. Diagnosis by In-111-labeled leukocyte scintigraphy. ( 10439196 )
1999
7
Blind loop syndrome: an unusual cause of panniculitis. ( 9366844 )
1997
8
Blind loop syndrome: multiple ileal ulcers following side-to-side anastomosis. ( 8165008 )
1993
9
The blind loop syndrome in children. ( 2401946 )
1990
10
The deconjugation ability of bacteria isolated from the jejunal fluids in the blind loop syndrome with high 14CO2 excretion--using the breath analysis technique and thin-layer chromatography. ( 2513463 )
1989
11
Percutaneous duodenostomy in blind loop syndrome. ( 2451880 )
1988
12
Impaired intestinal sodium and chloride transport in the blind loop syndrome of the rat. ( 2434383 )
1987
13
Adaptation of the jejunal mucosa in the experimental blind loop syndrome: changes in paracellular conductance and tight junction structure. ( 3692303 )
1987
14
Ischemic jejunal stenosis and blind loop syndrome after blunt abdominal trauma. ( 3559122 )
1987
15
Blind loop syndrome, vitamin E malabsorption, and spinocerebellar degeneration. ( 3974892 )
1985
16
Postgastrectomy blind loop syndrome and the arthritis-dermatitis syndrome. ( 3970735 )
1985
17
Choledochoduodenostomy and the blind loop syndrome. ( 4041721 )
1985
18
Breath hydrogen test in infants and children with blind loop syndrome. ( 6737180 )
1984
19
Altered motility and duration of bacterial overgrowth in experimental blind loop syndrome. ( 6376005 )
1984
20
Blind loop syndrome and small bowel bacterial contamination. ( 6347463 )
1983
21
Altered myoelectric activity in the experimental blind loop syndrome. ( 6350361 )
1983
22
Blind loop syndrome following iatrogenic intestinal bypass in a child. ( 7141516 )
1982
23
Gut damage in human blind-loop syndrome. ( 7239120 )
1981
24
Protein-losing enteropathy in the human and experimental rat blind-loop syndrome. ( 7450442 )
1981
25
Glycoprotein degradation in the blind loop syndrome: identification of glycosidases in jejunal contents. ( 6257760 )
1981
26
Importance of anaerobic bacteria in the cobalamin malabsorption of the experimental rat blind loop syndrome. ( 7450422 )
1981
27
Sensitivity of bile acid breath test in the diagnosis of bacterial overgrowth in the small intestine with and without the stagnant (blind) loop syndrome. ( 428288 )
1979
28
Osteomalacia complicating a blind loop syndrome from congenital megaesophagus-megaduodenum. ( 439112 )
1979
29
Protein digestion and absorption in the blind loop syndrome. ( 510093 )
1979
30
Pathogenesis of mucosal injury in the blind loop syndrome. ( 359400 )
1978
31
Enterotoxigenicity of colonising coliform bacteria in tropical sprue and blind-loop syndrome. ( 79710 )
1978
32
Xylose catabolism in the experimental rat blind loop syndrome: studies, including use of a newly developed d-[14C]xylose breath test. ( 631506 )
1978
33
Diagnosis of blind-loop syndrome by X-ray/breath-hydrogen test. ( 64837 )
1977
34
Brush border peptidases and arylamidases in the experimental blind loop syndrome of the rat. ( 930537 )
1977
35
Pathogenesis of mucosal injury in the blind loop syndrome. Brush border enzyme activity and glycoprotein degradation. ( 410830 )
1977
36
Enzyme activities of jejunal mucosa in experimental blind loop syndrome of rat. ( 6913 )
1976
37
Gastrointestinal bleeding and iron absorption in the experimental blind loop syndrome. ( 1084685 )
1976
38
Intestinal blind pouch- and blind loop-syndrome in children operated previously for congenital duodenal obstruction. ( 1267407 )
1976
39
Intestinal blind pouch- and blind loop- syndrome in children operated previously for congenital duodenal obstruction. ( 1032876 )
1976
40
The uptake of vitamin B12 by the sediment of jejunal contents in patients with the blind-loop syndrome. ( 1138334 )
1975
41
Kinetics of bile acid metabolism in experimental blind loop syndrome. ( 1218814 )
1975
42
Small intestinal mucosal injury in the experimental blind loop syndrome. Light- and electron-microscopic and histochemical studies. ( 1126607 )
1975
43
Functional, biochemical and morphological alterations in the intestines of rats with an experimental blind-loop syndrome. ( 1202590 )
1975
44
The absorption of vitamin B12 in the blind-loop syndrome. ( 4215127 )
1974
45
Blind loop syndrome. ( 4594535 )
1974
46
Jejunal brush border injury and impaired sugar and amino acid uptake in the blind loop syndrome. ( 4426497 )
1974
47
Blind loop syndrome associated with growth retardation. ( 4847713 )
1974
48
The mechanism of vitamin B 12 malabsorption in blind-loop syndrome. ( 4572448 )
1973
49
Ileal resection, or disease, and the blind loop syndrome: current concepts of pathophysiology. ( 4576987 )
1973
50
Post-traumatic blind-loop syndrome. ( 4774767 )
1973

Variations for Blind Loop Syndrome

Expression for Blind Loop Syndrome

Search GEO for disease gene expression data for Blind Loop Syndrome.

Pathways for Blind Loop Syndrome

GO Terms for Blind Loop Syndrome

Sources for Blind Loop Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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