CO
MCID: BLD165
MIFTS: 27

Blood Group, Colton System (CO)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group, Colton System

MalaCards integrated aliases for Blood Group, Colton System:

Name: Blood Group, Colton System 57
Colton Blood Group System 57 29
Co 57 3
Blood Group System, Colton 40
Aquaporin-1 Deficiency 57
Aquaporin-1 13

Classifications:



External Ids:

OMIM 57 110450

Summaries for Blood Group, Colton System

OMIM : 57 Colton is a relatively simple blood group system consisting of a single polymorphism, with high and low incidence alleles represented by Co(a) and Co(b) antigens, respectively. A third antigen, Co3, is present on all cells, save those of the null phenotype, Co(a-b-) (summary by Daniels, 2002). The Colton-null phenotype, Co(a-b-), is also known as aquaporin-1 deficiency. (110450)

MalaCards based summary : Blood Group, Colton System, also known as colton blood group system, is related to co-trimoxazole allergy and twin-to-twin transfusion syndrome. An important gene associated with Blood Group, Colton System is AQP1 (Aquaporin 1 (Colton Blood Group)). Affiliated tissues include brain, kidney and liver.

CDC : 3 CAS No. 7440-48-4

Related Diseases for Blood Group, Colton System

Diseases related to Blood Group, Colton System via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1927)
# Related Disease Score Top Affiliating Genes
1 co-trimoxazole allergy 12.3
2 twin-to-twin transfusion syndrome 11.5
3 attention deficit-hyperactivity disorder 11.2
4 pulmonary alveolar microlithiasis 11.2
5 pain - chronic 11.2
6 pelger-huet anomaly 11.2
7 developmental coordination disorder 11.2
8 whiplash 11.2
9 vacterl association 11.2
10 hypotonia 11.2
11 cortisone reductase deficiency 11.0
12 meconium ileus 11.0
13 cobalt allergic contact dermatitis 11.0
14 cobalt allergic asthma 11.0
15 isolated duane retraction syndrome 11.0
16 carbon monoxide-induced parkinsonism 11.0
17 dystonia, dopa-responsive 10.9
18 trichodentoosseous syndrome 10.9
19 mitochondrial dna depletion syndrome 4a 10.9
20 fucosidosis 10.9
21 mitochondrial complex i deficiency 10.9
22 gonadoblastoma 10.9
23 lathosterolosis 10.9
24 erythroderma, ichthyosiform, congenital reticular 10.9
25 heart-hand syndrome, slovenian type 10.9
26 aromatase deficiency 10.9
27 powassan encephalitis 10.9
28 good syndrome 10.9
29 social emotional agnosia 10.9
30 tabes dorsalis 10.9
31 hemoglobinopathy 10.9
32 vulvitis 10.9
33 cerebellar agenesis 10.9
34 paroxysmal exertion-induced dyskinesia 10.9
35 phacomatosis pigmentovascularis 10.9
36 infantile hypotonia 10.9
37 progressive locomotor ataxia 10.9
38 syphilitic spinal sclerosis 10.9
39 floppy infant syndrome 10.9
40 hepatitis 10.4
41 chronic interstitial cystitis 10.3
42 hepatitis c 10.2
43 depression 10.2
44 hepatitis b 10.2
45 malaria 10.2
46 breast cancer 10.2
47 anxiety 10.2
48 hepatitis c virus 10.2
49 adenocarcinoma 10.1
50 influenza 10.1

Graphical network of the top 20 diseases related to Blood Group, Colton System:



Diseases related to Blood Group, Colton System

Symptoms & Phenotypes for Blood Group, Colton System

Clinical features from OMIM:

110450

Drugs & Therapeutics for Blood Group, Colton System

Search Clinical Trials , NIH Clinical Center for Blood Group, Colton System

Genetic Tests for Blood Group, Colton System

Genetic tests related to Blood Group, Colton System:

# Genetic test Affiliating Genes
1 Colton Blood Group System 29 AQP1

Anatomical Context for Blood Group, Colton System

MalaCards organs/tissues related to Blood Group, Colton System:

41
Brain, Kidney, Liver, Bone, Heart, T Cells, B Cells

Publications for Blood Group, Colton System

Articles related to Blood Group, Colton System:

# Title Authors Year
1
A review of the Colton blood group system. ( 20795314 )
2010
2
A silenced allele in the Colton blood group system. ( 20345514 )
2010
3
A functional AQP1 allele producing a Co(a-b-) phenotype revises and extends the Colton blood group system. ( 20492605 )
2010
4
Exclusion of the red blood cell antigen Fra from the Colton blood group system. ( 7368269 )
1980

Variations for Blood Group, Colton System

Expression for Blood Group, Colton System

Search GEO for disease gene expression data for Blood Group, Colton System.

Pathways for Blood Group, Colton System

GO Terms for Blood Group, Colton System

Sources for Blood Group, Colton System

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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