MCID: BLD052
MIFTS: 26

Blood Group Incompatibility

Categories: Blood diseases

Aliases & Classifications for Blood Group Incompatibility

MalaCards integrated aliases for Blood Group Incompatibility:

Name: Blood Group Incompatibility 12 56 45 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4176
MeSH 45 D001787
UMLS 74 C0005806

Summaries for Blood Group Incompatibility

MalaCards based summary : Blood Group Incompatibility is related to kernicterus and infertility. An important gene associated with Blood Group Incompatibility is SLC4A1 (Solute Carrier Family 4 Member 1 (Diego Blood Group)). The drug Bilirubin has been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and kidney.

Related Diseases for Blood Group Incompatibility

Graphical network of the top 20 diseases related to Blood Group Incompatibility:



Diseases related to Blood Group Incompatibility

Symptoms & Phenotypes for Blood Group Incompatibility

Drugs & Therapeutics for Blood Group Incompatibility

Drugs for Blood Group Incompatibility (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bilirubin Not Applicable 635-65-4, 69853-43-6 5280352 21252250

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization Completed NCT00199628
2 Transcutaneous Bilirubinometers in the Community Completed NCT00735319 Not Applicable

Search NIH Clinical Center for Blood Group Incompatibility

Cochrane evidence based reviews: blood group incompatibility

Genetic Tests for Blood Group Incompatibility

Anatomical Context for Blood Group Incompatibility

MalaCards organs/tissues related to Blood Group Incompatibility:

42
Bone, Bone Marrow, Kidney, Endothelial, Liver, Myeloid

Publications for Blood Group Incompatibility

Articles related to Blood Group Incompatibility:

(show top 50) (show all 73)
# Title Authors Year
1
ABO blood group incompatibility and infertility: still an open debate. ( 28104243 )
2017
2
ABO blood group incompatibility as an adverse risk factor for outcomes in patients with myelodysplastic syndromes and acute myeloid leukemia undergoing HLA-matched peripheral blood hematopoietic cell transplantation after reduced-intensity conditioning. ( 26446051 )
2015
3
Predictive value of cord blood bilirubin for hyperbilirubinemia in neonates at risk for maternal-fetal blood group incompatibility and hemolytic disease of the newborn. ( 26518407 )
2015
4
CD144(+) endothelial microparticles as a marker of endothelial injury in neonatal ABO blood group incompatibility. ( 24333075 )
2013
5
Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1. ( 23878048 )
2013
6
Effect of ABO Blood Group Incompatibility on the Outcome of Single-Unit Cord Blood Transplantation after Myeloablative Conditioning. ( 24368297 )
2013
7
Homografts in aortic position: does blood group incompatibility have an impact on patient outcomes? ( 23390142 )
2013
8
ABO blood group incompatibility: a diminishing barrier to successful kidney transplantation? ( 20979554 )
2010
9
Mother-child blood group incompatibility and the risk of multiple sclerosis. ( 19795153 )
2010
10
Spectrum and outcome analysis of marked neonatal hyperbilirubinemia with blood group incompatibility. ( 19664346 )
2009
11
Impact of AB0-blood group incompatibility on the outcome of recipients of bone marrow transplants from unrelated donors in the Japan Marrow Donor Program. ( 18835834 )
2008
12
Blood group incompatibility in kidney transplantation: definitely time to re-examine! ( 17767439 )
2007
13
ABO-histo blood group incompatibility in hematopoietic stem cell and solid organ transplantation. ( 16935028 )
2006
14
Blood group incompatibility and accelerated homograft fibrocalcifications. ( 14752436 )
2004
15
Islet cell autoantibodies in cord blood from children with blood group incompatibility or hyperbilirubinemia. ( 12820693 )
2003
16
HLA-DR11 in addition to donor age, gender, and major blood group incompatibility influence the incidence of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. ( 12826219 )
2003
17
Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. ( 11245041 )
1998
18
Combination of ABO blood group incompatibility and glucose-6-phosphate dehydrogenase deficiency: effect on hemolysis and neonatal hyperbilirubinemia. ( 9628306 )
1998
19
ABO blood group incompatibility in liver transplantation: a single-centre experience. ( 9152158 )
1997
20
Differences in clinical significance of maternal-infant blood group incompatibility in mothers with blood type O, A, or B. ( 7844689 )
1995
21
Relationship between donor-recipient blood group incompatibility and serum bilirubin after allogeneic bone marrow transplantation from HLA-identical siblings. ( 7581080 )
1995
22
Bone marrow transplantation with major ABO blood group incompatibility using automated removal of red blood cells from incompatible bone marrow by CS 3000 plus. ( 8066772 )
1994
23
Removal of maternal antibodies from a woman with repeated fetal loss due to P blood group incompatibility. ( 8073488 )
1994
24
Prevalence and lack of clinical significance of blood group incompatibility in mothers with blood type A or B. ( 8021795 )
1994
25
The clinical significance of ABO blood group incompatibility. ( 8252149 )
1993
26
Maternal-child blood group incompatibility and other perinatal events increase the risk for early-onset type 1 (insulin-dependent) diabetes mellitus. ( 1644246 )
1992
27
High-dose intravenous gammaglobulin therapy for neonatal immune haemolytic jaundice due to blood group incompatibility. ( 1709770 )
1991
28
ABO blood group incompatibility and primary tooth discoloration. ( 2639328 )
1989
29
Bone marrow transplantation in Polish conditions. Method for removal of red cells from the transplant in the case of major blood group incompatibility. ( 2639626 )
1989
30
ABO blood group incompatibility and infertility in Nigerian couples. ( 3583322 )
1987
31
Human cadaver renal transplantation in the presence of ABO blood group incompatibility. ( 3296359 )
1987
32
AB0 blood group incompatibility and inbreeding effects: evidence for an interaction. ( 3972416 )
1985
33
Familial occurrence of hemolytic disease of the newborn due to AO blood group incompatibility. ( 3972392 )
1985
34
Blood group incompatibility in bone marrow transplantation. ( 6346604 )
1983
35
Transfusion reactions in cats due to AB blood group incompatibility. ( 6635340 )
1983
36
Fetomaternal blood group incompatibility studies in placental intervillous thrombosis. ( 6672809 )
1983
37
Bone marrow transplantation with major ABO blood group incompatibility using erythrocyte depletion of marrow prior to infusion. ( 7046847 )
1982
38
Renal transplant in a patient with major donor-recipient blood group incompatibility: reversal of acute rejection by the use of modified plasmapheresis. ( 7015598 )
1981
39
ABO blood group incompatibility differentials in reproductive performance with respect to maternal age and parity among Dawoodi Bohras of Udaipur, Rajasthan. ( 7341446 )
1981
40
Current clinical concepts in hemolytic disease and blood group incompatibility. ( 6273933 )
1981
41
Current concepts in hemolytic disease and blood group incompatibility. ( 6969353 )
1980
42
Preeclampsia, neonatal asphyxia and ABO blood group incompatibility. ( 457202 )
1979
43
Blood group incompatibility and cervical hostility in relation to sterility. ( 622233 )
1978
44
Significance of HLA and blood-group incompatibility in spontaneous abortion. ( 819191 )
1976
45
Unexplained infertility and ABO blood group incompatibility. ( 1027620 )
1976
46
Practical effects of blood group incompatibility between mother and fetus. ( 4630468 )
1973
47
Blood group incompatibility between mother and foetus. ( 4114342 )
1972
48
Practical effects of blood group incompatibility between mother and fetus. ( 5062951 )
1972
49
Evaluation of a simple method for determination of IgG titre anti-A or-B in cases of possible ABO blood group incompatibility. ( 5032414 )
1972
50
Blood group incompatibility and immunoglobulin levels. ( 4104378 )
1971

Variations for Blood Group Incompatibility

Expression for Blood Group Incompatibility

Search GEO for disease gene expression data for Blood Group Incompatibility.

Pathways for Blood Group Incompatibility

GO Terms for Blood Group Incompatibility

Cellular components related to Blood Group Incompatibility according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vesicle GO:0031982 8.62 ABO CSH1

Biological processes related to Blood Group Incompatibility according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione metabolic process GO:0006749 9.16 G6PD GGT5
2 ammonium transmembrane transport GO:0072488 8.96 RHCE RHD
3 ammonium transport GO:0015696 8.62 RHCE RHD

Molecular functions related to Blood Group Incompatibility according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ammonium transmembrane transporter activity GO:0008519 8.62 RHCE RHD

Sources for Blood Group Incompatibility

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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