JK
MCID: BLD167
MIFTS: 17

Blood Group, Kidd System (JK)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group, Kidd System

MalaCards integrated aliases for Blood Group, Kidd System:

Name: Blood Group, Kidd System 57
Blood Group--Kidd System 29
Kidd Blood Group System 57
Blood Group, Kidd 57
Jk 57

Classifications:



External Ids:

OMIM® 57 111000
MedGen 41 C0022645

Summaries for Blood Group, Kidd System

OMIM® : 57 The Kidd blood group locus encodes a urea transporter (SLC14A1) that is expressed on human red cells and in the kidney. The Kidd blood group system (Jk) is defined by 2 alleles, Jk(a) and Jk(b), whose products were first identified with alloantibodies responsible for haemolytic disease of the newborn or transfusion reactions (summary by Olives et al., 1997). (111000) (Updated 05-Mar-2021)

MalaCards based summary : Blood Group, Kidd System, also known as blood group--kidd system, is related to kidney disease and chronic kidney disease. An important gene associated with Blood Group, Kidd System is SLC14A1 (Solute Carrier Family 14 Member 1 (Kidd Blood Group)). Affiliated tissues include kidney, heart and endothelial.

Related Diseases for Blood Group, Kidd System

Diseases related to Blood Group, Kidd System via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 kidney disease 10.1
2 chronic kidney disease 10.1

Symptoms & Phenotypes for Blood Group, Kidd System

Clinical features from OMIM®:

111000 (Updated 05-Mar-2021)

Drugs & Therapeutics for Blood Group, Kidd System

Search Clinical Trials , NIH Clinical Center for Blood Group, Kidd System

Genetic Tests for Blood Group, Kidd System

Genetic tests related to Blood Group, Kidd System:

# Genetic test Affiliating Genes
1 Blood Group--Kidd System 29 SLC14A1

Anatomical Context for Blood Group, Kidd System

MalaCards organs/tissues related to Blood Group, Kidd System:

40
Kidney, Heart, Endothelial

Publications for Blood Group, Kidd System

Articles related to Blood Group, Kidd System:

(show all 43)
# Title Authors PMID Year
1
Partial deletion in the JK locus causing a Jk(null) phenotype. 57
11807016 2002
2
The molecular basis of the Kidd blood group polymorphism and its lack of association with type 1 diabetes susceptibility. 57
9215669 1997
3
Endothelial cells of the kidney vasa recta express the urea transporter HUT11. 57
8995727 1997
4
Evidence for distinct vascular and tubular urea transporters in the rat kidney. 57
8793793 1996
5
Urinary concentrating ability in patients with Jk(a-b-) blood type who lack carrier-mediated urea transport. 57
1498276 1992
6
The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLP. 57
2890568 1987
7
Analysis of the linkage JK-IGK, MNS-GC and of two other possible linkage groups. 57
3477523 1987
8
Linkage disequilibrium between insulin-dependent diabetes and the Kidd blood group Jkb allele. 57
6951830 1982
9
Close genetic linkage between diabetes mellitus and kidd blood group. 57
6117683 1981
10
Colton blood groups: indication of linkage with the Kidd (Jk) system as support for assignment to chromosome 7. 57
862214 1977
11
Proceedings: Linkage data on AcP1 and MNSs. 57
4827476 1974
12
Deletion of the long arm of chromosome no. 7: tentative assignment of the Kidd (Jk) locus. 57
4518278 1973
13
Possible localization of the genes for the Kidd blood group on an autosome involved in a reciprocal translocation. 57
5970105 1966
14
Severe hemolytic disease of the fetus and newborn due to anti-E and anti-Jka. 61
32667819 2020
15
Genotyping and serotyping profiles showed weak Jka presentation for previously typed as Jknull donors. 61
30820956 2019
16
Management of the blood supply for a Jk(a-b-) patient with an anti-Jk3 in preparation for an urgent heart transplant: An illustrative example of a successful international cooperation. 61
29802018 2019
17
Lack of association between Kidd blood group system and chronic kidney disease. 61
29150101 2017
18
The Kidd (JK) Blood Group System. 61
28065763 2017
19
Profile of Rh, Kell, Duffy, Kidd, and Diego blood group systems among blood donors in the Southwest region of the Paraná state, Southern Brazil. 61
27566949 2016
20
Red cell antigen prevalence predicted by molecular testing in ethnic groups of South Texas blood donors. 61
27187198 2015
21
Kidd blood group system: a review. 61
26308468 2015
22
Production of human monoclonal anti-Jk3, recognising an epitope including the Jk(a) /Jk(b) polymorphic site of the Kidd glycoprotein. 61
25180691 2014
23
JK null alleles identified from Japanese individuals with Jk(a−b−) phenotype. 61
24877238 2014
24
Implications of the Kidd blood group system in renal transplantation. 61
23286555 2012
25
[Kidd blood group system and antibodies]. 61
20942184 2010
26
A genetic strategy to control expression of human blood group antigens in red blood cells generated in vitro. 61
19175544 2009
27
The manual Polybrene test has limited sensitivities for detecting the Kidd blood group system. 61
19929723 2009
28
The value of DNA analysis for antigens of the Kidd blood group system. 61
17593282 2007
29
[Kidd blood group system and antibodies (anti-Jk(a), anti-Jk(b))]. 61
16111372 2005
30
Acute transplant rejection induced by blood transfusion reaction to the Kidd blood group system. 61
15299103 2004
31
[Kidd blood group system and antibodies (anti-Jka, anti-Jkb)]. 61
10635928 1999
32
Prenatal genotyping of Jk(a) and Jk(b) of the human Kidd blood group system by allele-specific polymerase chain reaction. 61
9885013 1998
33
IgG anti-Jka/Jkb antibodies are unlikely to fix complement. 61
9675791 1998
34
Blood group gene frequency in a selected north Indian population. 61
9378531 1997
35
Temporary suppression of Kidd system antigen expression accompanied by transient production of anti-Jk3. 61
2296791 1990
36
Investigation of genetic markers in a true hermaphrodite with chi 46,XX/46,XY. 61
6955258 1982
37
Further evidence of heterogeneity within the Kidd blood group system. 61
59434 1976
38
The Kidd blood group system in caucasians. 61
5860070 1965
39
[The Kidd blood group system in the population of Santiago]. 61
5864588 1965
40
[THE KIDD BLOOD GROUP SYSTEM IN THE POPULATION OF SANTIAGO]. 61
14242629 1964
41
Evidence for a new allele in the Kidd blood group system in Indians of northern Mato Grosso, Brazil. 61
14446744 1960
42
The phenotype Jk(a-b-) in the Kidd blood group system. 61
13669429 1959
43
The Kidd blood group system investigated with anti-JKa. 61
13301737 1956

Variations for Blood Group, Kidd System

Expression for Blood Group, Kidd System

Search GEO for disease gene expression data for Blood Group, Kidd System.

Pathways for Blood Group, Kidd System

GO Terms for Blood Group, Kidd System

Sources for Blood Group, Kidd System

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
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30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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45 MESH via Orphanet
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49 NCI
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51 NDF-RT
53 NINDS
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56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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