LAN
MCID: BLD148
MIFTS: 24

Blood Group, Langereis System (LAN)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group, Langereis System

MalaCards integrated aliases for Blood Group, Langereis System:

Name: Blood Group, Langereis System 58
Blood Group System, Langereis 41
Lan 58

Classifications:



External Ids:

OMIM 58 111600
MedGen 43 C3276339

Summaries for Blood Group, Langereis System

OMIM : 58 Individuals with Lan(-) blood group lack the Lan antigen on their red blood cells. These individuals may have anti-Lan antibodies in their serum, which can cause transfusion reactions or hemolytic disease of the fetus or newborn. The Lan(-) blood group is only clinically significant in transfusion settings or during pregnancy; otherwise Lan(-) individuals have no clinical features (summary by Helias et al., 2012). (111600)

MalaCards based summary : Blood Group, Langereis System, also known as blood group system, langereis, is related to aging and blood group, junior system. An important gene associated with Blood Group, Langereis System is ABCB6 (ATP Binding Cassette Subfamily B Member 6 (Langereis Blood Group)). Affiliated tissues include lung, breast and skeletal muscle.

Related Diseases for Blood Group, Langereis System

Diseases related to Blood Group, Langereis System via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 aging 10.5
2 blood group, junior system 10.3
3 breast cancer 10.2
4 lung cancer 10.1
5 blood group--kell system 9.9
6 multiple sclerosis 9.9
7 neutrophil migration 9.9
8 osteoporosis 9.9
9 small cell cancer of the lung 9.9
10 neuroblastoma 1 9.9
11 horns in sheep 9.9
12 welander distal myopathy 9.9
13 blood group, vel system 9.9
14 diabetes mellitus 9.9
15 dengue shock syndrome 9.9
16 dementia 9.9
17 porphyria 9.9
18 frozen shoulder 9.9
19 acromegaly 9.9
20 severe acute respiratory syndrome 9.9
21 compartment syndrome 9.9
22 influenza 9.9
23 autoimmune progesterone dermatitis 9.9

Graphical network of the top 20 diseases related to Blood Group, Langereis System:



Diseases related to Blood Group, Langereis System

Symptoms & Phenotypes for Blood Group, Langereis System

Clinical features from OMIM:

111600

Drugs & Therapeutics for Blood Group, Langereis System

Search Clinical Trials , NIH Clinical Center for Blood Group, Langereis System

Genetic Tests for Blood Group, Langereis System

Anatomical Context for Blood Group, Langereis System

MalaCards organs/tissues related to Blood Group, Langereis System:

42
Lung, Breast, Skeletal Muscle, Colon, Testes, Prostate, Neutrophil

Publications for Blood Group, Langereis System

Articles related to Blood Group, Langereis System:

(show top 50) (show all 199)
# Title Authors Year
1
The Effect of Time Synchronization Error in LAN-Based Digital Substation. ( 31052465 )
2019
2
Is the LAN effect in morphosyntactic processing an ERP artifact? ( 30731324 )
2019
3
A New Approach Using AHP to Generate Landslide Susceptibility Maps in the Chen-Yu-Lan Watershed, Taiwan. ( 30691107 )
2019
4
Reply to Lan and Shi: Different Background, Short Duration, and Inappropriate Participants May Harm Your Conclusion. ( 30335471 )
2019
5
Increased activin A levels in prediabetes and association with carotid intima-media thickness: a cross-sectional analysis from I-Lan Longitudinal Aging Study. ( 29967428 )
2018
6
"Socio-cultural transmission" in language evolution?: Comment on "Rethinking [the] foundations of language from a multidisciplinary perspective" by Tao Gong, Lan Shuai, & Yicheng Wu. ( 30477686 )
2018
7
The biological and the social in the origin and development of language: Comment on "Rethinking foundations of language from a multidisciplinary perspective" by Tao Gong, Lan Shuai, Yicheng Wu. ( 30477684 )
2018
8
Nguyen Trong Lan, MD, PhD. ( 30350773 )
2018
9
Elucidation of the mechanism of reflowering in tree peony (Paeonia suffruticosa) 'Zi Luo Lan' by defoliation and gibberellic acid application. ( 30326436 )
2018
10
Clinical significance of antibodies to antigens in the Raph, John Milton Hagen, I, Globoside, Gill, Rh-associated glycoprotein, FORS, JR, LAN, Vel, CD59, and Augustine blood group systems. ( 30295501 )
2018
11
Biology Matters: Comment on "Rethinking foundations of language from a multidisciplinary perspective" by Tao Gong, Lan Shuai, Yicheng Wu. ( 30078475 )
2018
12
Foundations of language and the recursion-only hypothesis: Comment on "Rethinking foundations of language from a multidisciplinary perspective" by Tao Gong, Lan Shuai and Yicheng Wu. ( 30049475 )
2018
13
Space, time, and language: Comment on "Rethinking foundations of language from a multidisciplinary perspective" by Tao Gong, Lan Shuai and Yicheng Wu. ( 30005973 )
2018
14
The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis. ( 29844288 )
2018
15
Cognitive Frailty and Its Association with All-Cause Mortality Among Community-Dwelling Older Adults in Taiwan: Results from I-Lan Longitudinal Aging Study. ( 29644921 )
2018
16
Association between serum uric acid and cardiovascular risk in nonhypertensive and nondiabetic individuals: The Taiwan I-Lan Longitudinal Aging Study. ( 29588485 )
2018
17
Folate receptor-targeted lipid-albumin nanoparticles (F-LAN) for therapeutic delivery of an Akt1 antisense oligonucleotide. ( 29376449 )
2018
18
Age-related changes of skeletal muscle mass and strength among Italian and Taiwanese older people: Results from the Milan EXPO 2015 survey and the I-Lan Longitudinal Aging Study. ( 29246506 )
2018
19
The Association Between Serum Activin A Levels and Hypertension in the Elderly: A Cross-Sectional Analysis From I-Lan Longitudinal Aging Study. ( 29182731 )
2018
20
Comment on "Serum human epididymis protein 4 is associated with the treatment response of concurrent chemo-radiotherapy and prognosis in patients with locally advanced non-small cell lung cancer" by Lan WG et al. ( 29063355 )
2018
21
FNIH-defined Sarcopenia Predicts Adverse Outcomes Among Community-Dwelling Older People in Taiwan: Results From I-Lan Longitudinal Aging Study. ( 28977377 )
2018
22
"Ulnar artery pseudoaneurysm and compartment syndrome formation after snake bite to the left forearm" by Lan Pin et al., Clin Toxicol (Phila) 2017 Nov. 10. ( 29260951 )
2018
23
8,4'-Oxyneolignane glucosides from an aqueous extract of "ban lan gen" (Isatis indigotica root) and their absolute configurations. ( 29159023 )
2017
24
Low-Energy Photoelectron Imaging Spectroscopy of Lan(benzene) (n = 1 and 2). ( 29061045 )
2017
25
Response to "Commentary on: Undertreatment trend in elderly lung cancer patients in Brazil"-Jing-lan Tang, Chun-jie Hou. ( 28875356 )
2017
26
Correction for Lan et al., Long-read sequencing uncovers the adaptive topography of a carnivorous plant genome. ( 28630343 )
2017
27
Aromatic compounds from an aqueous extract of "ban lan gen" and their antiviral activities. ( 28303224 )
2017
28
A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry. ( 28741071 )
2017
29
Association between low-grade albuminuria and frailty among community-dwelling middle-aged and older people: a cross-sectional analysis from I-Lan Longitudinal Aging Study. ( 28000719 )
2016
30
The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. ( 27480179 )
2016
31
Period of public commentary begins on the revised proposal of species-group level names, and on the proposal of genus-group level names of the Candidate Part of List of Available Names (LAN) in the phylum Rotifera. ( 27395533 )
2016
32
Lipid-Albumin Nanoparticles (LAN) for Therapeutic Delivery of Antisense Oligonucleotide against HIF-1α. ( 27253378 )
2016
33
Tumor Growth Rate (TGR) as an Indicator of Antitumor Activity With Lanreotide Autogel/Depot (LAN) Versus Placebo (Pbo) in Intestinal/Pancreatic NET: Post Hoc Analysis of CLARINET Data. ( 27168103 )
2016
34
Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor. ( 26987505 )
2016
35
Manual for proposing a Part of the List of Available Names (LAN) in Zoology. ( 26884699 )
2016
36
The List of Available Names (LAN): A new generation for stable taxonomic names in zoology? ( 26877661 )
2016
37
The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. ( 27507172 )
2016
38
454-Sequencing™ for the KEL, JR, and LAN Blood Groups. ( 26024631 )
2015
39
Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes. ( 26594235 )
2015
40
Association of Frailty and Cardiometabolic Risk Among Community-Dwelling Middle-Aged and Older People: Results from the I-Lan Longitudinal Aging Study. ( 26556635 )
2015
41
Anion Photoelectron Spectroscopy and CASSCF/CASPT2/RASSI Study of Lan(-) (n = 1, 3-7). ( 26503562 )
2015
42
Association between Frailty, Osteoporosis, Falls and Hip Fractures among Community-Dwelling People Aged 50 Years and Older in Taiwan: Results from I-Lan Longitudinal Aging Study. ( 26348034 )
2015
43
Cognitive Function in Individuals With Physical Frailty but Without Dementia or Cognitive Complaints: Results From the I-Lan Longitudinal Aging Study. ( 26321467 )
2015
44
Crystal structure of bis-{(Z)-(benzyl-amino)[(5Z)-2-(benzyl-imino-κN)-5-(2-meth-oxy-2-oxo-ethyl-idene)-4-oxo-thio-lan-3-yl-idene]methane-thiol-ato-κS}copper(II). ( 26029418 )
2015
45
Efficacy and safety of Ban-Lan-Gen granules in the treatment of seasonal influenza: study protocol for a randomized controlled trial. ( 25873046 )
2015
46
Quantitation of Lan antigen in Lan+, Lan+(w) and Lan- phenotypes. ( 25761317 )
2015
47
On the left anterior negativity (LAN): The case of morphosyntactic agreement: a reply to Tanner et al. ( 25017646 )
2015
48
On the left anterior negativity (LAN) in electrophysiological studies of morphosyntactic agreement: a commentary on "grammatical agreement processing in reading: ERP findings and future directions" by Molinaro et al., 2014. ( 24928489 )
2015
49
Molecular analysis of immunized Jr(a-) or Lan- patients and validation of a high-throughput genotyping assay to screen blood donors for Jr(a-) and Lan- phenotypes. ( 24456066 )
2014
50
Sarcopenia, and its association with cardiometabolic and functional characteristics in Taiwan: results from I-Lan Longitudinal Aging Study. ( 24450559 )
2014

Variations for Blood Group, Langereis System

ClinVar genetic disease variations for Blood Group, Langereis System:

6 (show all 16)
# Gene Variation Type Significance SNP ID Assembly Location
1 ABCB6 NM_005689.3(ABCB6): c.717G> A (p.Trp239Ter) single nucleotide variant Affects rs148458820 GRCh38 Chromosome 2, 219216803: 219216803
2 ABCB6 NM_005689.3(ABCB6): c.717G> A (p.Trp239Ter) single nucleotide variant Affects rs148458820 GRCh37 Chromosome 2, 220081525: 220081525
3 ABCB6 NM_005689.3(ABCB6): c.1690_1691del (p.Met564Valfs) deletion Affects rs387906908 GRCh37 Chromosome 2, 220078189: 220078190
4 ABCB6 NM_005689.3(ABCB6): c.1690_1691del (p.Met564Valfs) deletion Affects rs387906908 GRCh38 Chromosome 2, 219213467: 219213468
5 ABCB6 NM_005689.3(ABCB6): c.1942C> T (p.Arg648Ter) single nucleotide variant Affects rs376664522 GRCh37 Chromosome 2, 220077135: 220077135
6 ABCB6 NM_005689.3(ABCB6): c.1942C> T (p.Arg648Ter) single nucleotide variant Affects rs376664522 GRCh38 Chromosome 2, 219212413: 219212413
7 ABCB6 NM_005689.3(ABCB6): c.1985_1986del (p.Leu662Profs) deletion Affects rs387906909 GRCh37 Chromosome 2, 220075813: 220075814
8 ABCB6 NM_005689.3(ABCB6): c.1985_1986del (p.Leu662Profs) deletion Affects rs387906909 GRCh38 Chromosome 2, 219211091: 219211092
9 ABCB6 NM_005689.3(ABCB6): c.2256+2T> G single nucleotide variant Affects GRCh37 Chromosome 2, 220075431: 220075431
10 ABCB6 NM_005689.3(ABCB6): c.2256+2T> G single nucleotide variant Affects GRCh38 Chromosome 2, 219210709: 219210709
11 ABCB6 NM_005689.3(ABCB6): c.1656-1G> A single nucleotide variant Affects rs879255549 GRCh37 Chromosome 2, 220078225: 220078225
12 ABCB6 NM_005689.3(ABCB6): c.1656-1G> A single nucleotide variant Affects rs879255549 GRCh38 Chromosome 2, 219213503: 219213503
13 ABCB6 NM_005689.3(ABCB6): c.1118_1124delCGGATCG (p.Ala373Glyfs) deletion Affects rs765925019 GRCh37 Chromosome 2, 220080749: 220080755
14 ABCB6 NM_005689.3(ABCB6): c.1118_1124delCGGATCG (p.Ala373Glyfs) deletion Affects rs765925019 GRCh38 Chromosome 2, 219216027: 219216033
15 ABCB6 NM_005689.4(ABCB6): c.574C> T (p.Arg192Trp) single nucleotide variant Affects rs149202834 GRCh38 Chromosome 2, 219217783: 219217783
16 ABCB6 NM_005689.4(ABCB6): c.574C> T (p.Arg192Trp) single nucleotide variant Affects rs149202834 GRCh37 Chromosome 2, 220082505: 220082505

Expression for Blood Group, Langereis System

Search GEO for disease gene expression data for Blood Group, Langereis System.

Pathways for Blood Group, Langereis System

GO Terms for Blood Group, Langereis System

Sources for Blood Group, Langereis System

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....