LW
MCID: BLD144
MIFTS: 11

Blood Group System, Landsteiner-Wiener (LW)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group System, Landsteiner-Wiener

MalaCards integrated aliases for Blood Group System, Landsteiner-Wiener:

Name: Blood Group System, Landsteiner-Wiener 57
Landsteiner-Wiener Blood Group System 57
Lw 57

Classifications:



External Ids:

OMIM 57 111250

Summaries for Blood Group System, Landsteiner-Wiener

OMIM : 57 The LW blood group antigens reside on a 42-kD red cell intercellular adhesion molecule designated ICAM4 (Bailly et al., 1994; Bailly et al., 1995). (111250)

MalaCards based summary : Blood Group System, Landsteiner-Wiener, also known as landsteiner-wiener blood group system, is related to epiphyseal dysplasia, microcephaly, and nystagmus and marden-walker syndrome. An important gene associated with Blood Group System, Landsteiner-Wiener is ICAM4 (Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group)).

Related Diseases for Blood Group System, Landsteiner-Wiener

Diseases related to Blood Group System, Landsteiner-Wiener via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 epiphyseal dysplasia, microcephaly, and nystagmus 11.3
2 marden-walker syndrome 10.3
3 pityriasis rubra pilaris 10.0
4 immune deficiency disease 10.0
5 diabetes mellitus 10.0
6 exocrine pancreatic insufficiency 10.0

Graphical network of the top 20 diseases related to Blood Group System, Landsteiner-Wiener:



Diseases related to Blood Group System, Landsteiner-Wiener

Symptoms & Phenotypes for Blood Group System, Landsteiner-Wiener

Clinical features from OMIM:

111250

Drugs & Therapeutics for Blood Group System, Landsteiner-Wiener

Search Clinical Trials , NIH Clinical Center for Blood Group System, Landsteiner-Wiener

Genetic Tests for Blood Group System, Landsteiner-Wiener

Anatomical Context for Blood Group System, Landsteiner-Wiener

Publications for Blood Group System, Landsteiner-Wiener

Variations for Blood Group System, Landsteiner-Wiener

ClinVar genetic disease variations for Blood Group System, Landsteiner-Wiener:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 ICAM4 ICAM4, 10-BP DEL, NT346 deletion Affects
2 ICAM4 NM_001544.4(ICAM4): c.299A> G (p.Gln100Arg) single nucleotide variant Affects rs77493670 GRCh38 Chromosome 19, 10287311: 10287311
3 ICAM4 NM_001544.4(ICAM4): c.299A> G (p.Gln100Arg) single nucleotide variant Affects rs77493670 GRCh37 Chromosome 19, 10397987: 10397987

Expression for Blood Group System, Landsteiner-Wiener

Search GEO for disease gene expression data for Blood Group System, Landsteiner-Wiener.

Pathways for Blood Group System, Landsteiner-Wiener

GO Terms for Blood Group System, Landsteiner-Wiener

Sources for Blood Group System, Landsteiner-Wiener

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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