LW
MCID: BLD144
MIFTS: 11

Blood Group System, Landsteiner-Wiener (LW)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group System, Landsteiner-Wiener

MalaCards integrated aliases for Blood Group System, Landsteiner-Wiener:

Name: Blood Group System, Landsteiner-Wiener 58
Landsteiner-Wiener Blood Group System 58
Lw 58

Classifications:



External Ids:

OMIM 58 111250

Summaries for Blood Group System, Landsteiner-Wiener

OMIM : 58 The LW blood group antigens reside on a 42-kD red cell intercellular adhesion molecule designated ICAM4 (Bailly et al., 1994; Bailly et al., 1995). (111250)

MalaCards based summary : Blood Group System, Landsteiner-Wiener, also known as landsteiner-wiener blood group system, is related to epiphyseal dysplasia, microcephaly, and nystagmus and marden-walker syndrome. An important gene associated with Blood Group System, Landsteiner-Wiener is ICAM4 (Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group)).

Related Diseases for Blood Group System, Landsteiner-Wiener

Diseases related to Blood Group System, Landsteiner-Wiener via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 epiphyseal dysplasia, microcephaly, and nystagmus 11.4
2 marden-walker syndrome 10.3
3 pityriasis rubra pilaris 10.0
4 immune deficiency disease 10.0
5 diabetes mellitus 10.0
6 exocrine pancreatic insufficiency 10.0
7 hemolytic anemia 10.0

Graphical network of the top 20 diseases related to Blood Group System, Landsteiner-Wiener:



Diseases related to Blood Group System, Landsteiner-Wiener

Symptoms & Phenotypes for Blood Group System, Landsteiner-Wiener

Clinical features from OMIM:

111250

Drugs & Therapeutics for Blood Group System, Landsteiner-Wiener

Search Clinical Trials , NIH Clinical Center for Blood Group System, Landsteiner-Wiener

Genetic Tests for Blood Group System, Landsteiner-Wiener

Anatomical Context for Blood Group System, Landsteiner-Wiener

Publications for Blood Group System, Landsteiner-Wiener

Variations for Blood Group System, Landsteiner-Wiener

ClinVar genetic disease variations for Blood Group System, Landsteiner-Wiener:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 ICAM4 NM_001544.4(ICAM4): c.299A> G (p.Gln100Arg) single nucleotide variant Affects rs77493670 GRCh37 Chromosome 19, 10397987: 10397987
2 ICAM4 NM_001544.4(ICAM4): c.299A> G (p.Gln100Arg) single nucleotide variant Affects rs77493670 GRCh38 Chromosome 19, 10287311: 10287311
3 ICAM4 ICAM4, 10-BP DEL, NT346 deletion Affects

Expression for Blood Group System, Landsteiner-Wiener

Search GEO for disease gene expression data for Blood Group System, Landsteiner-Wiener.

Pathways for Blood Group System, Landsteiner-Wiener

GO Terms for Blood Group System, Landsteiner-Wiener

Sources for Blood Group System, Landsteiner-Wiener

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
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43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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