WR
MCID: BLD151
MIFTS: 15

Blood Group--Wright Antigen (WR)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group--Wright Antigen

MalaCards integrated aliases for Blood Group--Wright Antigen:

Name: Blood Group--Wright Antigen 58 30 6
Wright Blood Group Antigen 58
Wr 58

Classifications:



External Ids:

OMIM 58 112050
MedGen 43 C1862190

Summaries for Blood Group--Wright Antigen

OMIM : 58 The Wright antigen, a 'private' blood group (see 111500), was found by Holman (1953). Although it is very rare, the early date of its discovery and the ready availability of testing sera led to a large number of persons and variety of populations being tested. The frequency of the gene for the Wr(a) antigen was found to be about 3 in 10,000 among Europeans (Mourant et al., 1978). (112050)

MalaCards based summary : Blood Group--Wright Antigen, also known as wright blood group antigen, is related to epiphyseal dysplasia, multiple, with early-onset diabetes mellitus and wiedemann-rautenstrauch syndrome. An important gene associated with Blood Group--Wright Antigen is SLC4A1 (Solute Carrier Family 4 Member 1 (Diego Blood Group)). Affiliated tissues include testes.

Related Diseases for Blood Group--Wright Antigen

Graphical network of the top 20 diseases related to Blood Group--Wright Antigen:



Diseases related to Blood Group--Wright Antigen

Symptoms & Phenotypes for Blood Group--Wright Antigen

Clinical features from OMIM:

112050

Drugs & Therapeutics for Blood Group--Wright Antigen

Search Clinical Trials , NIH Clinical Center for Blood Group--Wright Antigen

Genetic Tests for Blood Group--Wright Antigen

Genetic tests related to Blood Group--Wright Antigen:

# Genetic test Affiliating Genes
1 Blood Group--Wright Antigen 30 SLC4A1

Anatomical Context for Blood Group--Wright Antigen

MalaCards organs/tissues related to Blood Group--Wright Antigen:

42
Testes

Publications for Blood Group--Wright Antigen

Variations for Blood Group--Wright Antigen

ClinVar genetic disease variations for Blood Group--Wright Antigen:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 SLC4A1 NM_000342.3(SLC4A1): c.1972G> A (p.Glu658Lys) single nucleotide variant Affects rs75731670 GRCh37 Chromosome 17, 42331949: 42331949
2 SLC4A1 NM_000342.3(SLC4A1): c.1972G> A (p.Glu658Lys) single nucleotide variant Affects rs75731670 GRCh38 Chromosome 17, 44254581: 44254581

Expression for Blood Group--Wright Antigen

Search GEO for disease gene expression data for Blood Group--Wright Antigen.

Pathways for Blood Group--Wright Antigen

GO Terms for Blood Group--Wright Antigen

Sources for Blood Group--Wright Antigen

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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