WR
MCID: BLD151
MIFTS: 12

Blood Group--Wright Antigen (WR)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Blood Group--Wright Antigen

MalaCards integrated aliases for Blood Group--Wright Antigen:

Name: Blood Group--Wright Antigen 57 29 6
Wright Blood Group Antigen 57
Wr 57

Classifications:



External Ids:

OMIM® 57 112050
MedGen 41 C1862190

Summaries for Blood Group--Wright Antigen

OMIM® : 57 The Wright antigen, a 'private' blood group (see 111500), was found by Holman (1953). Although it is very rare, the early date of its discovery and the ready availability of testing sera led to a large number of persons and variety of populations being tested. The frequency of the gene for the Wr(a) antigen was found to be about 3 in 10,000 among Europeans (Mourant et al., 1978). (112050) (Updated 20-May-2021)

MalaCards based summary : Blood Group--Wright Antigen, is also known as wright blood group antigen. An important gene associated with Blood Group--Wright Antigen is SLC4A1 (Solute Carrier Family 4 Member 1 (Diego Blood Group)).

Related Diseases for Blood Group--Wright Antigen

Symptoms & Phenotypes for Blood Group--Wright Antigen

Clinical features from OMIM®:

112050 (Updated 20-May-2021)

Drugs & Therapeutics for Blood Group--Wright Antigen

Search Clinical Trials , NIH Clinical Center for Blood Group--Wright Antigen

Genetic Tests for Blood Group--Wright Antigen

Genetic tests related to Blood Group--Wright Antigen:

# Genetic test Affiliating Genes
1 Blood Group--Wright Antigen 29 SLC4A1

Anatomical Context for Blood Group--Wright Antigen

Publications for Blood Group--Wright Antigen

Articles related to Blood Group--Wright Antigen:

# Title Authors PMID Year
1
Changes in the blood group Wright antigens are associated with a mutation at amino acid 658 in human erythrocyte band 3: a site of interaction between band 3 and glycophorin A under certain conditions. 6 57
7812009 1995
2
A new rare human bloodgroup antigen (Wra). 57
13070555 1953

Variations for Blood Group--Wright Antigen

ClinVar genetic disease variations for Blood Group--Wright Antigen:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 SLC4A1 NM_000342.4(SLC4A1):c.1972G>A (p.Glu658Lys) SNV Affects 17759 rs75731670 GRCh37: 17:42331949-42331949
GRCh38: 17:44254581-44254581
2 SLC4A1 NM_000342.4(SLC4A1):c.1765C>T (p.Arg589Cys) SNV Pathogenic 17764 rs121912745 GRCh37: 17:42333076-42333076
GRCh38: 17:44255708-44255708

Expression for Blood Group--Wright Antigen

Search GEO for disease gene expression data for Blood Group--Wright Antigen.

Pathways for Blood Group--Wright Antigen

GO Terms for Blood Group--Wright Antigen

Sources for Blood Group--Wright Antigen

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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