Body Dysmorphic Disorder disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BDY001 MIFTS: 44	Body Dysmorphic Disorder Categories: Mental diseases, Neuronal diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Body Dysmorphic Disorder

MalaCards integrated aliases for Body Dysmorphic Disorder:

Name: Body Dysmorphic Disorder ¹² ⁷⁶ ³⁷ ¹⁵

Dysmorphophobia ¹² ⁷⁶

Body Dysmorphic Disorders ⁷³

Dysmorphic Syndrome ¹²

Body Dysmorphia ¹²

Classifications:

MalaCards categories:
Anatomical: Mental diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060163

KEGG ³⁷ H01447

UMLS ⁷³ C0005887

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Summaries for Body Dysmorphic Disorder

Disease Ontology : ¹² A somatoform disorder that involves an excessive concern about and preoccupation with a perceived defect in his or her physical features (body image).

MalaCards based summary : Body Dysmorphic Disorder, also known as dysmorphophobia, is related to hypoparathyroidism-retardation-dysmorphism syndrome and macrocephaly, macrosomia, and facial dysmorphism syndrome. An important gene associated with Body Dysmorphic Disorder is SLITRK1 (SLIT And NTRK Like Family Member 1), and among its related pathways/superpathways are Serotonergic synapse and Glycosaminoglycan metabolism. The drugs Piracetam and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and skin.

Wikipedia : ⁷⁶ Body dysmorphic disorder (BDD), occasionally still called dysmorphophobia, is a mental disorder... more...

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Related Diseases for Body Dysmorphic Disorder

Diseases related to Body Dysmorphic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)

#	Related Disease	Score
1	hypoparathyroidism-retardation-dysmorphism syndrome	12.3
2	macrocephaly, macrosomia, and facial dysmorphism syndrome	12.2
3	hypoparathyroidism-intellectual disability-dysmorphism syndrome	12.2
4	aids dysmorphic syndrome	12.1
5	choanal atresia-hearing loss-cardiac defects-craniofacial dysmorphism syndrome	12.1
6	intellectual disability-severe speech delay-mild dysmorphism syndrome	12.1
7	night blindness-skeletal anomalies-dysmorphism syndrome	11.9
8	hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome	11.9
9	intellectual disability-expressive aphasia-facial dysmorphism syndrome	11.9
10	congenital labioscrotal agenesis-cerebellar malformation-corneal dystrophy-facial dysmorphism syndrome	11.9
11	birk-barel syndrome	11.9
12	thin ribs-tubular bones-dysmorphism syndrome	11.8
13	short stature-deafness-neutrophil dysfunction-dysmorphism syndrome	11.8
14	intellectual disability-obesity-brain malformations-facial dysmorphism syndrome	11.8
15	intellectual disability-muscle weakness-short stature-facial dysmorphism syndrome	11.8
16	microcephaly-short stature-intellectual disability-facial dysmorphism syndrome	11.8
17	x-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome	11.8
18	metopic ridging-ptosis-facial dysmorphism syndrome	11.8
19	osteopenia-myopia-hearing loss-intellectual disability-facial dysmorphism syndrome	11.8
20	x-linked intellectual disability-epilepsy-progressive joint contractures-dysmorphism syndrome	11.8
21	xia-gibbs syndrome	11.4
22	arachnodactyly - intellectual disability - dysmorphism	11.4
23	epiphyseal dysplasia hearing loss dysmorphism	11.4
24	kcnk9 imprinting syndrome	11.4
25	culler-jones syndrome	11.0
26	epileptic encephalopathy, early infantile, 23	11.0
27	short stature, hearing loss, retinitis pigmentosa, and distinctive facies	11.0
28	fibromatosis, gingival, with distinctive facies	10.8
29	hirschsprung disease with hypoplastic nails and dysmorphic facial features	10.8
30	spinocerebellar ataxia with dysmorphism	10.8
31	cubitus valgus with mental retardation and unusual facies	10.8
32	fryns macrocephaly	10.8
33	dislocation of hip, congenital, with hyperextensibility of fingers and facial dysmorphism	10.8
34	spondylometaphyseal dysplasia with bowed forearms and facial dysmorphism	10.8
35	burn-mckeown syndrome	10.8
36	mental retardation with language impairment and with or without autistic features	10.8
37	beaulieu-boycott-innes syndrome	10.8
38	steel syndrome	10.8
39	mental retardation, autosomal recessive 39	10.8
40	mental retardation, autosomal dominant 23	10.8
41	tatton-brown-rahman syndrome	10.8
42	mental retardation, autosomal dominant 36	10.8
43	klippel-feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism	10.8
44	mental retardation and distinctive facial features with or without cardiac defects	10.8
45	skraban-deardorff syndrome	10.8
46	med13l haploinsufficiency syndrome	10.8
47	reunion island larsen syndrome	10.8
48	cono-spondylar dysplasia	10.8
49	acromegaloid facial appearance syndrome	10.7
50	microcephalic primordial dwarfism, montreal type	10.7

Graphical network of the top 20 diseases related to Body Dysmorphic Disorder:

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Symptoms & Phenotypes for Body Dysmorphic Disorder

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Drugs & Therapeutics for Body Dysmorphic Disorder

Drugs for Body Dysmorphic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Piracetam

Approved, Investigational

Phase 4

7491-74-9

Fluoxetine

Approved, Vet_approved

Phase 4

54910-89-3

3386

Norepinephrine

Approved

Phase 4

51-41-2

439260

Etiracetam

Investigational

Phase 4

33996-58-6

Nootropic Agents

Phase 4

Neuroprotective Agents

Phase 4

Anticonvulsants

Phase 4

Protective Agents

Phase 4,Phase 2

Serotonin Agents

Phase 4,Phase 3,Phase 2

Psychotropic Drugs

Phase 4,Phase 3,Phase 2

Neurotransmitter Uptake Inhibitors

Phase 4,Phase 3,Phase 2

Antidepressive Agents, Second-Generation

Phase 4,Phase 3

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Antidepressive Agents

Phase 4,Phase 3

Serotonin Uptake Inhibitors

Phase 4,Phase 3,Phase 2

Neurotransmitter Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Cytochrome P-450 CYP2D6 Inhibitors

Phase 4

Serotonin and Noradrenaline Reuptake Inhibitors

Phase 4

Venlafaxine Hydrochloride

Phase 4

Serotonin

Investigational, Nutraceutical

Phase 4,Phase 3,Phase 2

50-67-9

5202

Citalopram

Approved

Phase 3

59729-33-8

2771

Cholinergic Agents

Phase 3

Parasympatholytics

Phase 3

Cholinergic Antagonists

Phase 3

Peripheral Nervous System Agents

Phase 3,Phase 2,Not Applicable

Muscarinic Antagonists

Phase 3

Autonomic Agents

Phase 3,Phase 2

Antiparkinson Agents

Phase 3,Not Applicable

Oxytocin

Approved, Vet_approved

Phase 2

50-56-6

439302 53477758

Milk thistle

Approved, Experimental, Investigational

Phase 2

65666-07-1

Ondansetron

Approved

Phase 2

99614-02-5

4595

Lactitol

Investigational

Phase 2

585-86-4

3871

Oxytocics

Phase 2

Hormones

Phase 2

Central Nervous System Depressants

Phase 2,Not Applicable

Antioxidants

Phase 2

silymarin

Phase 2

Serotonin Antagonists

Phase 2

Tranquilizing Agents

Phase 2

Anti-Anxiety Agents

Phase 2

Dermatologic Agents

Phase 2

Antipsychotic Agents

Phase 2

Gastrointestinal Agents

Phase 2

Antipruritics

Phase 2

Antiemetics

Phase 2

Cycloserine

Approved

Early Phase 1

68-41-7

6234 401

Dopamine

Approved

Not Applicable

51-61-6, 62-31-7

681

Memantine

Approved, Investigational

Not Applicable

19982-08-2

4054

Cocaine

Approved, Illicit

Not Applicable

50-36-2

5760 446220

Diprenorphine

Illicit, Vet_approved

Not Applicable

14357-78-9

Interventional clinical trials:

(show all 38)

#	Name	Status	NCT ID	Phase	Drugs
1	Effectiveness of Levetiracetam in the Treatment of Body Dysmorphic Disorder	Completed	NCT00265109	Phase 4	Levetiracetam
2	Fluoxetine in Pediatric Body Dysmorphic Disorder	Completed	NCT00245635	Phase 4	Fluoxetine;Placebo
3	CBT as an Adjunct to SRIs in the Treatment of BDD	Terminated	NCT00211809	Phase 4	Venlafaxine
4	Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder	Completed	NCT00149799	Phase 3	Escitalopram;Placebo
5	Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions	Unknown status	NCT01316627	Phase 2
6	Oxytocin Administration in BDD and OCD	Completed	NCT02671266	Phase 2	Oxytocin;Placebo
7	Milk Thistle in Body Dysmorphic Disorder	Recruiting	NCT02843451	Phase 2	Milk Thistle;Placebo
8	Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder	Terminated	NCT01275248	Phase 2	Ondansetron;Placebo
9	Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder	Unknown status	NCT01453439	Not Applicable
10	Body Image and Self-Care in HIV-Infected MSM	Unknown status	NCT01817621	Not Applicable
11	Interpretation Bias Modification for Body Dysmorphic Disorder	Completed	NCT02635152	Not Applicable
12	Attentional Bias in Body Dysmorphic Disorder	Completed	NCT01398904
13	Internet Cognitive Behavior Therapy (CBT) for Body Dysmorphic Disorder (BDD)	Completed	NCT01850433	Not Applicable
14	D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder	Completed	NCT00842309	Early Phase 1	d-cycloserine;Placebo
15	Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder	Completed	NCT00106223	Not Applicable
16	Cognitive-Behavioral Therapy for Pediatric Body Dysmorphic Disorder	Completed	NCT01002326	Not Applicable
17	Internet Delivered CBT for Body Dysmorphic Disorder	Completed	NCT02010619	Not Applicable
18	An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder	Completed	NCT01038128	Not Applicable	Memantine
19	Prevention of Body Image Disorder by Nurse Intervention on the Patient and Family Prior to Breast and Colon Surgery	Completed	NCT03726801	Not Applicable
20	Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD)	Completed	NCT00871143	Not Applicable
21	Escitalopram Neuroimaging Supplement	Completed	NCT01398865
22	Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study	Completed	NCT02524301	Not Applicable	Positron Emission Tomography using [11C]diprenorphine
23	Assessment of Body Image in Patients With Rheumatoid Arthritis	Completed	NCT00832910
24	Effectiveness of Dance on Patients With Fibromyalgia	Completed	NCT00961805	Not Applicable
25	Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)	Completed	NCT02381639	Not Applicable
26	Cortical Excitability in Obsessive-Compulsive and Related Disorders	Completed	NCT00029068
27	Contribution of a Virtual Reality Program in the Treatment of Dysmorphophobia for Adolescent Female With Anorexia Nervosa	Recruiting	NCT03426930	Not Applicable
28	Body Image Disorder in Anorexia Nervosa and Virtual Reality	Recruiting	NCT03118921	Not Applicable
29	Brain Correlates of Self-Focused Processing	Recruiting	NCT02808702	Not Applicable
30	White Light Scanning to Aid Body Contouring: A Pilot Project	Recruiting	NCT01093950
31	The Pride Body Project	Recruiting	NCT03451513	Not Applicable
32	Feasibility Pilot Study of Internet-based Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder With Global Recruitment	Active, not recruiting	NCT03517384	Not Applicable
33	Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder	Active, not recruiting	NCT03221738	Not Applicable
34	Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals	Active, not recruiting	NCT01075672	Not Applicable
35	A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder	Not yet recruiting	NCT03773549
36	Waitlist-Control Trial of Smartphone CBT for Body Dysmorphic Disorder (BDD)	Not yet recruiting	NCT03673046	Not Applicable
37	Effects of Mindfulness Meditation on Rhinoplasty Outcomes	Not yet recruiting	NCT03727815	Not Applicable
38	Benefits of a Psychoeducation Program for Those Awaiting Treatment for OCD and OCD Spectrum Disorders	Withdrawn	NCT01953042	Not Applicable

Search NIH Clinical Center for Body Dysmorphic Disorder

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Genetic Tests for Body Dysmorphic Disorder

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Anatomical Context for Body Dysmorphic Disorder

MalaCards organs/tissues related to Body Dysmorphic Disorder:

⁴¹

Brain, Eye, Skin, Testes, Bone, Heart, Neutrophil

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Publications for Body Dysmorphic Disorder

Articles related to Body Dysmorphic Disorder:

(show top 50) (show all 627)

#	Title	Authors	Year
1	Shame and Defectiveness Beliefs in Treatment Seeking Patients With Body Dysmorphic Disorder. ( 29557815 )	Weingarden H....Wilhelm S.	2018
2	Escalation from normal appearance related intrusive cognitions to clinical preoccupations in Body Dysmorphic Disorder: A cross-sectional study. ( 29704773 )	Giraldo-O'Meara M....Belloch A.	2018
3	New perspectives in the treatment of body dysmorphic disorder. ( 29636904 )	Hong K....Hollander E.	2018
4	A systematic review and meta-analysis of cognitive processing deficits associated with body dysmorphic disorder. ( 29935380 )	Johnson S....Wade T.D.	2018
5	Patients Screening Positive for Body Dysmorphic Disorder Show No Significant Health-Related Quality of Life Gain after Functional Septorhinoplasty at a Tertiary Referral Center. ( 29702720 )	Bulut O.C....Hohenberger R.	2018
6	Body dysmorphic disorder: a guide to identification and management for the orthodontic team. ( 29952250 )	Rosten A....Newton J.T.	2018
7	The classification of body dysmorphic disorder symptoms in male and female adolescents. ( 28858657 )		2018
8	Non-weight-related body image concerns and Body Dysmorphic Disorder prevalence in patients with Anorexia Nervosa. ( 29886274 )		2018
9	Pharmacological Treatment Of Body Dysmorphic Disorder. ( 29701157 )		2018
10	Body dysmorphic disorder in the cosmetic practice. ( 29667794 )		2018
11	Cosmetic Surgery and Body Dysmorphic Disorder - An Update. ( 29872676 )		2018
12	Aberrant Dynamic Connectivity for Fear Processing in Anorexia Nervosa and Body Dysmorphic Disorder. ( 29997532 )	Rangaprakash D...Feusner JD	2018
13	Influencing Factors of Social Anxiety Disorder and Body Dysmorphic Disorder in a Nonclinical Brazilian Population. ( 30388392 )	Tatiana Soler P...Miguel Fernandes H	2018
14	An experimental test of the role of appearance-related safety behaviors in body dysmorphic disorder, social anxiety, and body dissatisfaction. ( 30307259 )	Summers BJ...Cougle JR	2018
15	Set shifting and visuospatial organization deficits in body dysmorphic disorder. ( 29202381 )	Greenberg JL...Wilhelm S	2018
16	Body dysmorphic disorder in pediatric dermatology. ( 29984846 )	Dennin MH...Lee MS	2018
17	Effects of induced appearance-related interpretation bias: A test of the cognitive-behavioral model of body dysmorphic disorder. ( 30118967 )	Dietel FA...Buhlmann U	2018
18	An initial investigation of the unique relationship between disgust propensity and body dysmorphic disorder. ( 30153602 )	Wilver NL...Cougle JR	2018
19	Prevalence of bullying in a pediatric sample of body dysmorphic disorder. ( 30193152 )	Neziroglu F...Bonasera B	2018
20	Conscious Perception of Facial Asymmetry in a Unilateral Cleft Lip Model: Body Dysmorphic Disorder Is an Exclusion Criterion. ( 30223679 )	Boriani F	2018
21	The relationship between body dysmorphic disorder and obsessive-compulsive disorder: A systematic review of direct comparative studies. ( 30238784 )	Malcolm A...Rossell SL	2018
22	Body dysmorphic disorder: A diagnostic challenge in adolescence. ( 30263210 )	Thungana Y...Lachman A	2018
23	Plastic surgery in gynaecology: Factors affecting women's decision to undergo labiaplasty. Mind the risk of body dysmorphic disorder: A review. ( 30351259 )	M?llerov? J...Weiss P	2018
24	A psychiatric condition ...: Body dysmorphic disorder: a guide to identification and management for the orthodontic team. ( 30412528 )		2018
25	Application of a transdiagnostic treatment for emotional disorders to body dysmorphic disorder: A randomized controlled trial. ( 30445389 )	Mohajerin B...Motabi F	2018
26	Skin, Body Dysmorphic Disorder, and Other Syndromes. ( 30482571 )	Mart?nez-Gonz?lez C	2018
27	Validation of Spanish Language Evaluation Instruments for Body Dysmorphic Disorder and the Dysmorphic Concern Construct. ( 28713311 )	SenA-n-CalderA^n C....RodrA-guez-Testal J.F.	2017
28	The neurobiology of body dysmorphic disorder: A systematic review and theoretical model. ( 29017915 )	Grace S.A....Rossell S.L.	2017
29	Prevalence of body dysmorphic disorder and associated features in German adolescents: A self-report survey. ( 28482195 )	MAPllmann A....Buhlmann U.	2017
30	Evaluation of the Body Parts That Preoccupy Adolescents With Body Dysmorphic Disorder. ( 29099545 )	Jafferany M....Osuagwu F.C.	2017
31	Neurocognitive Functioning in Young Adults with Subclinical Body Dysmorphic Disorder. ( 28367586 )	Blum A.W....Grant J.E.	2017
32	Long-Term Outcomes of Cognitive-Behavioral Therapy for Adolescent Body Dysmorphic Disorder. ( 28577583 )	Krebs G....Mataix-Cols D.	2017
33	Body dysmorphic disorder: A serious concern for our young generation. ( 28784390 )	Jangda A.A....Shah S.R.	2017
34	Insight in body dysmorphic disorder (BDD) relative to obsessive-compulsive disorder (OCD) and psychotic disorders: Revisiting this issue in light of DSM-5. ( 28651226 )	Toh W.L....Rossell S.L.	2017
35	Face and Object Perception in Body Dysmorphic Disorder versus Obsessive-Compulsive Disorder: The Mooney Faces Task. ( 28528596 )	Toh W.L....Rossell S.L.	2017
36	[Body dysmorphic disorder : Diagnostics and treatment in cosmetic dermatology]. ( 29075869 )	Lahousen T....Gieler U.	2017
37	How individuals with body dysmorphic disorder (BDD) process their own face: a quantitative and qualitative investigation based on an eye-tracking paradigm. ( 28322616 )	Toh W.L....Rossell S.L.	2017
38	Body Dysmorphic Disorder in Patients With Autism Spectrum Disorder: A Reflection of Increased Local Processing and Self-Focus. ( 28366095 )	Vasudeva S.B....Hollander E.	2017
39	Prevalence of Body Dysmorphic Disorder in Plastic Surgery and Dermatology Patients: A Systematic Review with Meta-Analysis. ( 28411353 )	Ribeiro R.V.E.	2017
40	Body dysmorphic disorder in female Swedish dermatology patients. ( 28960272 )	Brohede S....Wijma K.	2017
41	A multi-method analysis of distress tolerance in body dysmorphic disorder. ( 28826046 )	Matheny N.L....Cougle J.R.	2017
42	Patient-identified events implicated in the development of body dysmorphic disorder. ( 28285175 )	Weingarden H....Wilhelm S.	2017
43	Visual selective attention in body dysmorphic disorder, bulimia nervosa and healthy controls. ( 27998509 )	Kollei I....Martin A.	2017
44	'Not just right' experiences and incompleteness in body dysmorphic disorder. ( 27918970 )	Summers B.J....Cougle J.R.	2017
45	Selfie use: The implications for psychopathology expression of body dysmorphic disorder. ( 29456333 )	Khanna A....Sharma M.K.	2017
46	A Review of Body Dysmorphic Disorder in Aesthetic Surgery Patients and the Legal Implications. ( 28204935 )	Sweis I.E....COHEN M.	2017
47	Recent advances in understanding and managing body dysmorphic disorder. ( 28729345 )	Krebs G....Mataix-Cols D.	2017
48	Body dysmorphic disorder: history and curiosities. ( 28220373 )		2017
49	An Aberrant Presentation of Delusional Body Dysmorphic Disorder - Importance of Early Psychiatry Liaison. ( 28479822 )		2017
50	Body dysmorphic disorder and its associated psychological and psychopathological features in an Italian community sample. ( 29069974 )		2017

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Genes for Body Dysmorphic Disorder

Genes related to Body Dysmorphic Disorder (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SLITRK1	SLIT And NTRK Like Family Member 1	Protein Coding	16.56	DISEASES inferred ¹⁵
2	SLC25A24	Solute Carrier Family 25 Member 24	Protein Coding	16.03	DISEASES inferred ¹⁵
3	TFCP2	Transcription Factor CP2	Protein Coding	15.46	DISEASES inferred ¹⁵
4	KCNJ16	Potassium Voltage-Gated Channel Subfamily J Member 16	Protein Coding	15.26	DISEASES inferred ¹⁵
5	VPS13B	Vacuolar Protein Sorting 13 Homolog B	Protein Coding	15.2	DISEASES inferred ¹⁵
6	GALE	UDP-Galactose-4-Epimerase	Protein Coding	15.19	DISEASES inferred ¹⁵
7	GPC6	Glypican 6	Protein Coding	15.17	DISEASES inferred ¹⁵
8	GPC1	Glypican 1	Protein Coding	15.06	DISEASES inferred ¹⁵
9	GPC3	Glypican 3	Protein Coding	14.68	DISEASES inferred ¹⁵

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Variations for Body Dysmorphic Disorder

Copy number variations for Body Dysmorphic Disorder from CNVD:

⁷

#	CNVD ID	Chromosom	Start	End	Type	Gene Symbol	CNVD Disease
1	63474	12	119100000	132349534	Deletion	FBXW8	dysmorphic
2	63477	12	119100000	132349534	Deletion	FZD10	dysmorphic
3	63480	12	119100000	132349534	Deletion	NCOR2	dysmorphic
4	63483	12	119100000	132349534	Deletion	P2RX2	dysmorphic
5	63486	12	119100000	132349534	Deletion	RAN	dysmorphic
6	63489	12	119100000	132349534	Deletion	STX2	dysmorphic
7	63492	12	119100000	132349534	Deletion	TBX3	dysmorphic
8	63495	12	119100000	132349534	Deletion	TESC	dysmorphic
9	63498	12	119100000	132349534	Deletion	ULK1	dysmorphic

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Expression for Body Dysmorphic Disorder

Search GEO for disease gene expression data for Body Dysmorphic Disorder.

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Pathways for Body Dysmorphic Disorder

Pathways related to Body Dysmorphic Disorder according to KEGG:

³⁷

#	Name	Kegg Source Accession
1	Serotonergic synapse	hsa04726

Pathways related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glycosaminoglycan metabolism ⁶⁶ Show member pathways chondroitin sulfate biosynthesis ¹ chondroitin sulfate biosynthesis (late stages) ¹ Heparan sulfate/heparin (HS-GAG) metabolism ⁶⁶ HS-GAG biosynthesis ⁶⁶ Hyaluronan biosynthesis and export ⁶⁶ Hyaluronan metabolism ⁶⁶ Hyaluronan uptake and degradation ⁶⁶ Metabolism of carbohydrates ⁶⁶	12.31	GALE GPC1 GPC3 GPC6
2	Metabolism of water-soluble vitamins and cofactors ⁶⁶ Show member pathways [2Fe-2S] iron-sulfur cluster biosynthesis ¹ Biotin transport and metabolism ⁶⁶ biotin-carboxyl carrier protein assembly ¹ coenzyme A biosynthesis ¹ Coenzyme A biosynthesis ⁶⁶ flavin biosynthesis ¹ folate polyglutamylation ¹ glycine/serine biosynthesis ¹ Metabolism of folate and pterines ⁶⁶ Metabolism of vitamins and cofactors ⁶⁶ molybdenum cofactor biosynthesis ¹ Molybdenum cofactor biosynthesis ⁶⁶ thiamin salvage III ¹ thio-molybdenum cofactor biosynthesis ¹ Vitamin B1 (thiamin) metabolism ⁶⁶ Vitamin B2 (riboflavin) metabolism ⁶⁶ Vitamin B5 (pantothenate) metabolism ⁶⁶ Vitamin C (ascorbate) metabolism ⁶⁶ Vitamins B6 activation to pyridoxal phosphate ⁶⁶	12.24	GPC1 GPC3 GPC6
3	Chondroitin sulfate/dermatan sulfate metabolism ⁶⁶ Show member pathways A tetrasaccharide linker sequence is required for GAG synthesis ⁶⁶ chondroitin biosynthesis ¹ Chondroitin sulfate biosynthesis ⁶⁶ CS/DS degradation ⁶⁶ Defective B3GALT6 causes EDSP2 and SEMDJL1 ⁶⁶ Defective B3GAT3 causes JDSSDHD ⁶⁶ Defective B4GALT7 causes EDS, progeroid type ⁶⁶ Defective CHST14 causes EDS, musculocontractural type ⁶⁶ Defective CHST3 causes SEDCJD ⁶⁶ Defective CHSY1 causes TPBS ⁶⁶ Defective EXT1 causes exostoses 1, TRPS2 and CHDS ⁶⁶ Defective EXT2 causes exostoses 2 ⁶⁶ dermatan sulfate biosynthesis ¹ Dermatan sulfate biosynthesis ⁶⁶ dermatan sulfate biosynthesis (late stages) ¹ Diseases associated with glycosaminoglycan metabolism ⁶⁶ glycoaminoglycan-protein linkage region biosynthesis ¹ Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate ³⁷ Glypican pathway ¹ HS-GAG degradation ⁶⁶ Proteogylcan syndecan-mediated signaling events ¹	12.12	GPC1 GPC3 GPC6
4	mTOR signaling pathway (KEGG) ⁶⁵ Show member pathways mTOR signaling pathway ³⁷	12.04	GPC1 GPC3 GPC6
5	Development VEGF signaling via VEGFR2 - generic cascades ²² Show member pathways Development VEGF signaling and activation ²² VEGF - VEGF R2 Signaling Pathways ⁶⁵	11.93	GPC1 GPC3 GPC6
6	Metabolism of fat-soluble vitamins ⁶⁶ Show member pathways Metabolism of vitamin K ⁶⁶ Retinoid metabolism and transport ⁶⁶ The retinoid cycle in cones (daylight vision) ⁶⁶ Visual phototransduction ⁶⁶ Vitamin D (calciferol) metabolism ⁶⁶	11.83	GPC1 GPC3 GPC6
7	Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling ⁶⁵ Show member pathways Basal cell carcinoma ³⁷	11.51	GPC1 GPC3 GPC6
8	Diseases of glycosylation ⁶⁶ Show member pathways Diseases associated with O-glycosylation of proteins ⁶⁶	11.3	GPC1 GPC3 GPC6
9	Microglia Activation During Neuroinflammation: Overview ⁶⁵ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁵	10.9	GPC1 GPC3 GPC6

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GO Terms for Body Dysmorphic Disorder

Cellular components related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	collagen-containing extracellular matrix	GO:0062023	9.54	GPC1 GPC3 GPC6
2	anchored component of membrane	GO:0031225	9.43	GPC1 GPC3 GPC6
3	Golgi lumen	GO:0005796	9.33	GPC1 GPC3 GPC6
4	intrinsic component of plasma membrane	GO:0031226	9.32	GPC1 GPC3
5	lysosomal lumen	GO:0043202	9.13	GPC1 GPC3 GPC6
6	anchored component of plasma membrane	GO:0046658	8.8	GPC1 GPC3 GPC6

Biological processes related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	retinoid metabolic process	GO:0001523	9.43	GPC1 GPC3 GPC6
2	regulation of signal transduction	GO:0009966	9.33	GPC1 GPC3 GPC6
3	glycosaminoglycan biosynthetic process	GO:0006024	9.13	GPC1 GPC3 GPC6
4	glycosaminoglycan catabolic process	GO:0006027	8.8	GPC1 GPC3 GPC6

Sources

Sources for Body Dysmorphic Disorder

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia