Body Dysmorphic Disorder disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BDY001 MIFTS: 45	Body Dysmorphic Disorder Categories: Mental diseases, Neuronal diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Body Dysmorphic Disorder

MalaCards integrated aliases for Body Dysmorphic Disorder:

Name: Body Dysmorphic Disorder ¹² ⁷⁷ ³⁸ ¹⁵

Dysmorphophobia ¹² ⁷⁷

Body Dysmorphic Disorders ⁷⁴

Dysmorphic Syndrome ¹²

Body Dysmorphia ¹²

Classifications:

MalaCards categories:
Anatomical: Mental diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0060163

KEGG ³⁸ H01447

UMLS ⁷⁴ C0005887

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Summaries for Body Dysmorphic Disorder

Disease Ontology : ¹² A somatoform disorder that involves an excessive concern about and preoccupation with a perceived defect in his or her physical features (body image).

MalaCards based summary : Body Dysmorphic Disorder, also known as dysmorphophobia, is related to hypoparathyroidism-retardation-dysmorphism syndrome and hypoparathyroidism-intellectual disability-dysmorphism syndrome. An important gene associated with Body Dysmorphic Disorder is TMEM94 (Transmembrane Protein 94), and among its related pathways/superpathways are Serotonergic synapse and Glycosaminoglycan metabolism. The drugs Levetiracetam and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include brain, breast and eye.

Wikipedia : ⁷⁷ Body dysmorphic disorder (BDD), occasionally still called dysmorphophobia, is a mental disorder... more...

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Related Diseases for Body Dysmorphic Disorder

Diseases related to Body Dysmorphic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)

#	Related Disease	Score
1	hypoparathyroidism-retardation-dysmorphism syndrome	12.4
2	hypoparathyroidism-intellectual disability-dysmorphism syndrome	12.2
3	aids dysmorphic syndrome	12.1
4	choanal atresia-hearing loss-cardiac defects-craniofacial dysmorphism syndrome	12.1
5	intellectual disability-severe speech delay-mild dysmorphism syndrome	12.1
6	night blindness-skeletal anomalies-dysmorphism syndrome	11.9
7	hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome	11.9
8	intellectual disability-expressive aphasia-facial dysmorphism syndrome	11.9
9	congenital labioscrotal agenesis-cerebellar malformation-corneal dystrophy-facial dysmorphism syndrome	11.9
10	birk-barel syndrome	11.9
11	overgrowth-macrocephaly-facial dysmorphism syndrome	11.9
12	thin ribs-tubular bones-dysmorphism syndrome	11.9
13	short stature-deafness-neutrophil dysfunction-dysmorphism syndrome	11.9
14	intellectual disability-obesity-brain malformations-facial dysmorphism syndrome	11.9
15	intellectual disability-muscle weakness-short stature-facial dysmorphism syndrome	11.9
16	microcephaly-short stature-intellectual disability-facial dysmorphism syndrome	11.9
17	metopic ridging-ptosis-facial dysmorphism syndrome	11.9
18	osteopenia-myopia-hearing loss-intellectual disability-facial dysmorphism syndrome	11.9
19	x-linked intellectual disability-epilepsy-progressive joint contractures-dysmorphism syndrome	11.9
20	arachnodactyly - intellectual disability - dysmorphism	11.5
21	epiphyseal dysplasia hearing loss dysmorphism	11.5
22	kcnk9 imprinting syndrome	11.4
23	burn-mckeown syndrome	11.2
24	xia-gibbs syndrome	11.1
25	epileptic encephalopathy, early infantile, 23	11.1
26	culler-jones syndrome	11.0
27	short stature, hearing loss, retinitis pigmentosa, and distinctive facies	11.0
28	fibromatosis, gingival, with distinctive facies	10.8
29	hirschsprung disease with hypoplastic nails and dysmorphic facial features	10.8
30	spinocerebellar ataxia with dysmorphism	10.8
31	cubitus valgus with mental retardation and unusual facies	10.8
32	deafness, x-linked 7	10.8
33	fryns macrocephaly	10.8
34	dislocation of hip, congenital, with hyperextensibility of fingers and facial dysmorphism	10.8
35	spondylometaphyseal dysplasia with bowed forearms and facial dysmorphism	10.8
36	mental retardation with language impairment and with or without autistic features	10.8
37	beaulieu-boycott-innes syndrome	10.8
38	steel syndrome	10.8
39	mental retardation, autosomal recessive 39	10.8
40	mental retardation, autosomal dominant 23	10.8
41	tatton-brown-rahman syndrome	10.8
42	mental retardation, autosomal dominant 36	10.8
43	klippel-feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism	10.8
44	smith-kingsmore syndrome	10.8
45	mental retardation and distinctive facial features with or without cardiac defects	10.8
46	skraban-deardorff syndrome	10.8
47	pilarowski-bjornsson syndrome	10.8
48	med13l haploinsufficiency syndrome	10.8
49	reunion island larsen-like syndrome	10.8
50	cono-spondylar dysplasia	10.8

Graphical network of the top 20 diseases related to Body Dysmorphic Disorder:

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Symptoms & Phenotypes for Body Dysmorphic Disorder

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Drugs & Therapeutics for Body Dysmorphic Disorder

Drugs for Body Dysmorphic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 64)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Levetiracetam

Approved, Investigational

Phase 4

102767-28-2

441341

Fluoxetine

Approved, Vet_approved

Phase 4

54910-89-3

3386

Norepinephrine

Approved

Phase 4

51-41-2

439260

Anticonvulsants

Phase 4

Nootropic Agents

Phase 4

Antidepressive Agents

Phase 4,Phase 3

Neurotransmitter Uptake Inhibitors

Phase 4,Phase 3,Phase 2

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Neurotransmitter Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Antidepressive Agents, Second-Generation

Phase 4,Phase 3

Serotonin Agents

Phase 4,Phase 3,Phase 2

Psychotropic Drugs

Phase 4,Phase 3,Phase 2

Serotonin Uptake Inhibitors

Phase 4,Phase 3,Phase 2

Cytochrome P-450 CYP2D6 Inhibitors

Phase 4

Venlafaxine Hydrochloride

Phase 4

Serotonin and Noradrenaline Reuptake Inhibitors

Phase 4

Serotonin

Investigational, Nutraceutical

Phase 4,Phase 3,Phase 2

50-67-9

5202

Citalopram

Approved

Phase 3

59729-33-8

2771

Autonomic Agents

Phase 3,Phase 2

Antiparkinson Agents

Phase 3,Not Applicable

Parasympatholytics

Phase 3

Peripheral Nervous System Agents

Phase 3,Phase 2,Not Applicable

Muscarinic Antagonists

Phase 3

Cholinergic Antagonists

Phase 3

Cholinergic Agents

Phase 3

Oxytocin

Approved, Vet_approved

Phase 2

50-56-6

53477758 439302

Milk thistle

Approved, Experimental, Investigational

Phase 2

65666-07-1

Ondansetron

Approved

Phase 2

99614-02-5

4595

Lactitol

Investigational

Phase 2

585-88-6, 585-86-4

493591

Oxytocics

Phase 2

Hormones

Phase 2

Central Nervous System Depressants

Phase 2,Not Applicable

Antioxidants

Phase 2

Protective Agents

Phase 2

silymarin

Phase 2

Dermatologic Agents

Phase 2

Serotonin Antagonists

Phase 2

Gastrointestinal Agents

Phase 2

Antiemetics

Phase 2

Tranquilizing Agents

Phase 2

Antipruritics

Phase 2

Anti-Anxiety Agents

Phase 2

Antipsychotic Agents

Phase 2

Serotonin Receptor Agonists

Phase 2

Cycloserine

Approved

Early Phase 1

68-41-7

6234 401

Dopamine

Approved

Not Applicable

62-31-7, 51-61-6

681

Memantine

Approved, Investigational

Not Applicable

19982-08-2

4054

Cocaine

Approved, Illicit

Not Applicable

50-36-2

446220 5760

Diprenorphine

Illicit, Vet_approved

Not Applicable

14357-78-9

Antibiotics, Antitubercular

Early Phase 1

Interventional clinical trials:

(show all 40)

#	Name	Status	NCT ID	Phase	Drugs
1	Effectiveness of Levetiracetam in the Treatment of Body Dysmorphic Disorder	Completed	NCT00265109	Phase 4	Levetiracetam
2	Fluoxetine in Pediatric Body Dysmorphic Disorder	Completed	NCT00245635	Phase 4	Fluoxetine;Placebo
3	CBT as an Adjunct to SRIs in the Treatment of BDD	Terminated	NCT00211809	Phase 4	Venlafaxine
4	Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder	Completed	NCT00149799	Phase 3	Escitalopram;Placebo
5	Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions	Unknown status	NCT01316627	Phase 2
6	Oxytocin Administration in BDD and OCD	Completed	NCT02671266	Phase 2	Oxytocin;Placebo
7	Milk Thistle in Body Dysmorphic Disorder	Recruiting	NCT02843451	Phase 2	Milk Thistle;Placebo
8	Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder	Terminated	NCT01275248	Phase 2	Ondansetron;Placebo
9	Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder	Unknown status	NCT01453439	Not Applicable
10	Body Image and Self-Care in HIV-Infected MSM	Unknown status	NCT01817621	Not Applicable
11	Interpretation Bias Modification for Body Dysmorphic Disorder	Completed	NCT02635152	Not Applicable
12	Attentional Bias in Body Dysmorphic Disorder	Completed	NCT01398904
13	Internet Cognitive Behavior Therapy (CBT) for Body Dysmorphic Disorder (BDD)	Completed	NCT01850433	Not Applicable
14	D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder	Completed	NCT00842309	Early Phase 1	d-cycloserine;Placebo
15	Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder	Completed	NCT00106223	Not Applicable
16	Cognitive-Behavioral Therapy for Pediatric Body Dysmorphic Disorder	Completed	NCT01002326	Not Applicable
17	Internet Delivered CBT for Body Dysmorphic Disorder	Completed	NCT02010619	Not Applicable
18	An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder	Completed	NCT01038128	Not Applicable	Memantine
19	Prevention of Body Image Disorder by Nurse Intervention on the Patient and Family Prior to Breast and Colon Surgery	Completed	NCT03726801	Not Applicable
20	Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD)	Completed	NCT00871143	Not Applicable
21	Escitalopram Neuroimaging Supplement	Completed	NCT01398865
22	Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study	Completed	NCT02524301	Not Applicable	Positron Emission Tomography using [11C]diprenorphine
23	Assessment of Body Image in Patients With Rheumatoid Arthritis	Completed	NCT00832910
24	Effectiveness of Dance on Patients With Fibromyalgia	Completed	NCT00961805	Not Applicable
25	Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA)	Completed	NCT02381639	Not Applicable
26	Cortical Excitability in Obsessive-Compulsive and Related Disorders	Completed	NCT00029068
27	A Virtual Reality Study of Cognitive Biases in Body Dysmorphic Disorder	Recruiting	NCT03773549
28	Contribution of a Virtual Reality Program in the Treatment of Dysmorphophobia for Adolescent Female With Anorexia Nervosa	Recruiting	NCT03426930	Not Applicable
29	Body Image Disorder in Anorexia Nervosa and Virtual Reality	Recruiting	NCT03118921	Not Applicable
30	Brain Correlates of Self-Focused Processing	Recruiting	NCT02808702	Not Applicable
31	White Light Scanning to Aid Body Contouring: A Pilot Project	Recruiting	NCT01093950
32	The Pride Body Project	Recruiting	NCT03451513	Not Applicable
33	Investigation of Physical Activity and Associated Factors in Lower Extremity Amputees	Recruiting	NCT03825432
34	Feasibility Pilot Study of Internet-based Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder With Global Recruitment	Active, not recruiting	NCT03517384	Not Applicable
35	Smartphone-Administered App Treatment for Adults With Body Dysmorphic Disorder	Active, not recruiting	NCT03221738	Not Applicable
36	Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals	Active, not recruiting	NCT01075672	Not Applicable
37	Waitlist-Control Trial of Smartphone CBT for Body Dysmorphic Disorder (BDD)	Not yet recruiting	NCT03673046	Not Applicable
38	Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders	Not yet recruiting	NCT03918577	Not Applicable
39	Effects of Mindfulness Meditation on Rhinoplasty Outcomes	Not yet recruiting	NCT03727815	Not Applicable
40	Benefits of a Psychoeducation Program for Those Awaiting Treatment for OCD and OCD Spectrum Disorders	Withdrawn	NCT01953042	Not Applicable

Search NIH Clinical Center for Body Dysmorphic Disorder

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Genetic Tests for Body Dysmorphic Disorder

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Anatomical Context for Body Dysmorphic Disorder

MalaCards organs/tissues related to Body Dysmorphic Disorder:

⁴²

Brain, Breast, Eye, Skin, Bone, Colon, Neutrophil

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Publications for Body Dysmorphic Disorder

Articles related to Body Dysmorphic Disorder:

(show top 50) (show all 649)

#	Title	Authors	Year
1	Direct comparisons of anorexia nervosa and body dysmorphic disorder: A systematic review. ( 30784781 )	Phillipou A...Rossell SL	2019
2	Body parts of clinical concern in anorexia nervosa versus body dysmorphic disorder: a cross-diagnostic comparison. ( 30931578 )	Toh WL...Phillipou A	2019
3	Differentiating weight-restored anorexia nervosa and body dysmorphic disorder using neuroimaging and psychometric markers. ( 31059514 )	Vaughn DA...Feusner JD	2019
4	Application of a transdiagnostic treatment for emotional disorders to body dysmorphic disorder: A randomized controlled trial. ( 30445389 )	Mohajerin B...Motabi F	2019
5	Skin, Body Dysmorphic Disorder, and Other Syndromes. ( 30482571 )	Mart?nez-Gonz?lez C	2019
6	An Internet-based controlled trial of interpretation bias modification versus progressive muscle relaxation for body dysmorphic disorder. ( 30589349 )	Wilver NL...Cougle JR	2019
7	High Prevalence of Body Dysmorphic Disorder and Moderate to Severe Appearance-Related Obsessive-Compulsive Symptoms Among Rhinoplasty Candidates. ( 30607575 )	Ramos TD...Ferreira LM	2019
8	Intranasal oxytocin modulates higher order social cognition in body dysmorphic disorder. ( 30614171 )	Fang A...Wilhelm S	2019
9	Long-term outcome of therapist-guided internet-based cognitive behavioural therapy for body dysmorphic disorder (BDD-NET): a naturalistic 2-year follow-up after a randomised controlled trial. ( 30647044 )	Enander J...R?ck C	2019
10	Body dysmorphic disorder and its relationship to sexuality, impulsivity, and addiction. ( 30658211 )	Grant JE...Chamberlain SR	2019
11	A Practical Guide to Managing Body Dysmorphic Disorder in the Cosmetic Surgery Setting. ( 30676626 )	Greenberg JL...Wilhelm S	2019
12	Body dysmorphic disorder: The drive for perfection. ( 30720669 )	Perkins A	2019
13	Understanding and treating body dysmorphic disorder. ( 30745686 )	Singh AR...Veale D	2019
14	Efficacy and Posttreatment Effects of Therapist-Delivered Cognitive Behavioral Therapy vs Supportive Psychotherapy for Adults With Body Dysmorphic Disorder: A Randomized Clinical Trial. ( 30785624 )	Wilhelm S...Schoenfeld DA	2019
15	Identifying Efficacious Treatment Elements for Refractory Conditions, Such as Body Dysmorphic Disorder. ( 30785632 )	Mennin DS	2019
16	Body dysmorphic disorder: The drive for perfection. ( 30801405 )		2019
17	Internet-based, therapist-guided, cognitive-behavioural therapy for body dysmorphic disorder with global eligibility for inclusion: an uncontrolled pilot study. ( 30904854 )	Gentile AJ...R?ck C	2019
18	The emergence of Exercise Addiction, Body Dysmorphic Disorder, and other image-related psychopathological correlates in fitness settings: A cross sectional study. ( 30943200 )	Corazza O...Martinotti G	2019
19	Low prevalence of body dysmorphic disorder in specific public and private practices in Australia. ( 30979400 )	Brignardello-Petersen R	2019
20	Body Dysmorphic Disorder: Is There an "Ideal" Strategy? ( 31011755 )	Morselli PG...Giorgini FA	2019
21	Pharmacotherapy in body dysmorphic disorder: relapse prevention and novel treatments. ( 31038370 )	Dong N...Hollander E	2019
22	Prevalence and clinical characteristics of body dysmorphic disorder in adolescent inpatient psychiatric patients-a pilot study. ( 31074670 )	Jafferany M...Roy N	2019
23	Impaired Recognition of Negative Facial Emotions in Body Dysmorphic Disorder. ( 31099324 )	Grace SA...Rossell SL	2019
24	Affect and worry during a checking episode: A comparison of individuals with symptoms of obsessive-compulsive disorder, anorexia nervosa, bulimia nervosa, body dysmorphic disorder, illness anxiety disorder, and panic disorder. ( 30599438 )	Hartmann AS...Vocks S	2018
25	Aberrant Dynamic Connectivity for Fear Processing in Anorexia Nervosa and Body Dysmorphic Disorder. ( 29997532 )	Rangaprakash D...Feusner JD	2018
26	Non-weight-related body image concerns and Body Dysmorphic Disorder prevalence in patients with Anorexia Nervosa. ( 29886274 )	Cerea S...Ghisi M	2018
27	Influencing Factors of Social Anxiety Disorder and Body Dysmorphic Disorder in a Nonclinical Brazilian Population. ( 30388392 )	Tatiana Soler P...Miguel Fernandes H	2018
28	An experimental test of the role of appearance-related safety behaviors in body dysmorphic disorder, social anxiety, and body dissatisfaction. ( 30307259 )	Summers BJ...Cougle JR	2018
29	Measurement Invariance of a Body Dysmorphic Disorder Symptom Questionnaire Across Sex: The Body Image Questionnaire-Child and Adolescent Version. ( 27866170 )	Schneider SC...Hudson JL	2018
30	Neurocognitive Functioning in Young Adults with Subclinical Body Dysmorphic Disorder. ( 28367586 )	Blum AW...Grant JE	2018
31	The classification of body dysmorphic disorder symptoms in male and female adolescents. ( 28858657 )	Schneider SC...Hudson JL	2018
32	Body dysmorphic disorder and its associated psychological and psychopathological features in an Italian community sample. ( 29069974 )	Cerea S...Ghisi M	2018
33	Set shifting and visuospatial organization deficits in body dysmorphic disorder. ( 29202381 )	Greenberg JL...Wilhelm S	2018
34	Shame and Defectiveness Beliefs in Treatment Seeking Patients With Body Dysmorphic Disorder. ( 29557815 )	Weingarden H...Wilhelm S	2018
35	New perspectives in the treatment of body dysmorphic disorder. ( 29636904 )	Hong K...Hollander E	2018
36	Body dysmorphic disorder in the cosmetic practice. ( 29667794 )	Kuhn H...Kroumpouzos G	2018
37	Pharmacological Treatment Of Body Dysmorphic Disorder. ( 29701157 )	Hong K...Hollander E	2018
38	Patients Screening Positive for Body Dysmorphic Disorder Show No Significant Health-Related Quality of Life Gain after Functional Septorhinoplasty at a Tertiary Referral Center. ( 29702720 )	Bulut OC...Hohenberger R	2018
39	Escalation from normal appearance related intrusive cognitions to clinical preoccupations in Body Dysmorphic Disorder: A cross-sectional study. ( 29704773 )	Giraldo-O'Meara M...Belloch A	2018
40	Cosmetic Surgery and Body Dysmorphic Disorder - An Update. ( 29872676 )	Higgins S...Wysong A	2018
41	A systematic review and meta-analysis of cognitive processing deficits associated with body dysmorphic disorder. ( 29935380 )	Johnson S...Wade TD	2018
42	Body dysmorphic disorder: a guide to identification and management for the orthodontic team. ( 29952250 )	Rosten A...Newton JT	2018
43	Body dysmorphic disorder in pediatric dermatology. ( 29984846 )	Dennin MH...Lee MS	2018
44	Effects of induced appearance-related interpretation bias: A test of the cognitive-behavioral model of body dysmorphic disorder. ( 30118967 )	Dietel FA...Buhlmann U	2018
45	An initial investigation of the unique relationship between disgust propensity and body dysmorphic disorder. ( 30153602 )	Wilver NL...Cougle JR	2018
46	Prevalence of bullying in a pediatric sample of body dysmorphic disorder. ( 30193152 )	Neziroglu F...Bonasera B	2018
47	Conscious Perception of Facial Asymmetry in a Unilateral Cleft Lip Model: Body Dysmorphic Disorder Is an Exclusion Criterion. ( 30223679 )	Boriani F	2018
48	The relationship between body dysmorphic disorder and obsessive-compulsive disorder: A systematic review of direct comparative studies. ( 30238784 )	Malcolm A...Rossell SL	2018
49	Body dysmorphic disorder: A diagnostic challenge in adolescence. ( 30263210 )	Thungana Y...Lachman A	2018
50	Plastic surgery in gynaecology: Factors affecting women's decision to undergo labiaplasty. Mind the risk of body dysmorphic disorder: A review. ( 30351259 )	M?llerov? J...Weiss P	2018

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Genes for Body Dysmorphic Disorder

Genes related to Body Dysmorphic Disorder (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TMEM94	Transmembrane Protein 94	Protein Coding	16.93	DISEASES inferred ¹⁵
2	SLITRK1	SLIT And NTRK Like Family Member 1	Protein Coding	16.56	DISEASES inferred ¹⁵
3	SLC25A24	Solute Carrier Family 25 Member 24	Protein Coding	15.95	DISEASES inferred ¹⁵
4	GPC6	Glypican 6	Protein Coding	15.92	DISEASES inferred ¹⁵
5	TFCP2	Transcription Factor CP2	Protein Coding	15.44	DISEASES inferred ¹⁵
6	KCNJ16	Potassium Voltage-Gated Channel Subfamily J Member 16	Protein Coding	15.19	DISEASES inferred ¹⁵
7	GPC1	Glypican 1	Protein Coding	15.07	DISEASES inferred ¹⁵
8	GPC4	Glypican 4	Protein Coding	14.98	DISEASES inferred ¹⁵
9	GPC3	Glypican 3	Protein Coding	14.68	DISEASES inferred ¹⁵

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Variations for Body Dysmorphic Disorder

Copy number variations for Body Dysmorphic Disorder from CNVD:

⁷

#	CNVD ID	Chromosom	Start	End	Type	Gene Symbol	CNVD Disease
1	63474	12	119100000	132349534	Deletion	FBXW8	dysmorphic
2	63477	12	119100000	132349534	Deletion	FZD10	dysmorphic
3	63480	12	119100000	132349534	Deletion	NCOR2	dysmorphic
4	63483	12	119100000	132349534	Deletion	P2RX2	dysmorphic
5	63486	12	119100000	132349534	Deletion	RAN	dysmorphic
6	63489	12	119100000	132349534	Deletion	STX2	dysmorphic
7	63492	12	119100000	132349534	Deletion	TBX3	dysmorphic
8	63495	12	119100000	132349534	Deletion	TESC	dysmorphic
9	63498	12	119100000	132349534	Deletion	ULK1	dysmorphic

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Expression for Body Dysmorphic Disorder

Search GEO for disease gene expression data for Body Dysmorphic Disorder.

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Pathways for Body Dysmorphic Disorder

Pathways related to Body Dysmorphic Disorder according to KEGG:

³⁸

#	Name	Kegg Source Accession
1	Serotonergic synapse	hsa04726

Pathways related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glycosaminoglycan metabolism ⁶⁷ Show member pathways chondroitin sulfate biosynthesis ¹ chondroitin sulfate biosynthesis (late stages) ¹ Heparan sulfate/heparin (HS-GAG) metabolism ⁶⁷ HS-GAG biosynthesis ⁶⁷ Hyaluronan biosynthesis and export ⁶⁷ Hyaluronan metabolism ⁶⁷ Hyaluronan uptake and degradation ⁶⁷ Metabolism of carbohydrates ⁶⁷	12.46	GPC1 GPC3 GPC4 GPC6
2	Metabolism of water-soluble vitamins and cofactors ⁶⁷ Show member pathways [2Fe-2S] iron-sulfur cluster biosynthesis ¹ Biotin transport and metabolism ⁶⁷ biotin-carboxyl carrier protein assembly ¹ coenzyme A biosynthesis ¹ Coenzyme A biosynthesis ⁶⁷ flavin biosynthesis ¹ folate polyglutamylation ¹ Metabolism of folate and pterines ⁶⁷ Metabolism of vitamins and cofactors ⁶⁷ molybdenum cofactor biosynthesis ¹ Molybdenum cofactor biosynthesis ⁶⁷ thiamin salvage III ¹ thio-molybdenum cofactor biosynthesis ¹ Vitamin B1 (thiamin) metabolism ⁶⁷ Vitamin B2 (riboflavin) metabolism ⁶⁷ Vitamin B5 (pantothenate) metabolism ⁶⁷ Vitamin C (ascorbate) metabolism ⁶⁷ Vitamins B6 activation to pyridoxal phosphate ⁶⁷	12.16	GPC1 GPC3 GPC4 GPC6
3	mTOR signaling pathway (KEGG) ³⁸ Show member pathways mTOR Signaling Pathway ⁶⁶	12.1	GPC1 GPC3 GPC6
4	Wnt Signaling Pathways: beta-Catenin-dependent Wnt Signaling ⁶⁶ Show member pathways Basal cell carcinoma ³⁸ Wnt signaling pathway ³⁸	12.03	GPC1 GPC3 GPC6
5	Development VEGF signaling via VEGFR2 - generic cascades ²³ Show member pathways Development VEGF signaling and activation ²³ VEGF - VEGF R2 Signaling Pathways ⁶⁶	12	GPC1 GPC3 GPC6
6	Chondroitin sulfate/dermatan sulfate metabolism ⁶⁷ Show member pathways A tetrasaccharide linker sequence is required for GAG synthesis ⁶⁷ chondroitin biosynthesis ¹ Chondroitin sulfate biosynthesis ⁶⁷ CS/DS degradation ⁶⁷ Defective B3GALT6 causes EDSP2 and SEMDJL1 ⁶⁷ Defective B3GAT3 causes JDSSDHD ⁶⁷ Defective B4GALT7 causes EDS, progeroid type ⁶⁷ Defective CHST14 causes EDS, musculocontractural type ⁶⁷ Defective CHST3 causes SEDCJD ⁶⁷ Defective CHSY1 causes TPBS ⁶⁷ Defective EXT1 causes exostoses 1, TRPS2 and CHDS ⁶⁷ Defective EXT2 causes exostoses 2 ⁶⁷ dermatan sulfate biosynthesis ¹ Dermatan sulfate biosynthesis ⁶⁷ dermatan sulfate biosynthesis (late stages) ¹ Diseases associated with glycosaminoglycan metabolism ⁶⁷ glycoaminoglycan-protein linkage region biosynthesis ¹ Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate ³⁸ Glypican pathway ¹ HS-GAG degradation ⁶⁷ Proteogylcan syndecan-mediated signaling events ¹	11.97	GPC1 GPC3 GPC4 GPC6
7	Microglia Activation During Neuroinflammation: Overview ⁶⁶ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁶	11.6	GPC1 GPC3 GPC6
8	Metabolism of fat-soluble vitamins ⁶⁷ Show member pathways Metabolism of vitamin K ⁶⁷ Retinoid metabolism and transport ⁶⁷ The retinoid cycle in cones (daylight vision) ⁶⁷ Visual phototransduction ⁶⁷ Vitamin D (calciferol) metabolism ⁶⁷	11.59	GPC1 GPC3 GPC4 GPC6
9	Diseases of glycosylation ⁶⁷ Show member pathways Diseases associated with O-glycosylation of proteins ⁶⁷	11.09	GPC1 GPC3 GPC4 GPC6

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GO Terms for Body Dysmorphic Disorder

Cellular components related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.83	GPC1 GPC3 GPC4 GPC6 SLITRK1
2	collagen-containing extracellular matrix	GO:0062023	9.62	GPC1 GPC3 GPC4 GPC6
3	glutamatergic synapse	GO:0098978	9.58	GPC4 GPC6 SLITRK1
4	anchored component of membrane	GO:0031225	9.56	GPC1 GPC3 GPC4 GPC6
5	Golgi lumen	GO:0005796	9.46	GPC1 GPC3 GPC4 GPC6
6	intrinsic component of plasma membrane	GO:0031226	9.37	GPC1 GPC3
7	lysosomal lumen	GO:0043202	9.26	GPC1 GPC3 GPC4 GPC6
8	anchored component of plasma membrane	GO:0046658	8.92	GPC1 GPC3 GPC4 GPC6

Biological processes related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	retinoid metabolic process	GO:0001523	9.56	GPC1 GPC3 GPC4 GPC6
2	regulation of signal transduction	GO:0009966	9.46	GPC1 GPC3 GPC4 GPC6
3	Wnt signaling pathway, planar cell polarity pathway	GO:0060071	9.43	GPC4 GPC6
4	regulation of presynapse assembly	GO:1905606	9.4	GPC4 SLITRK1
5	synaptic membrane adhesion	GO:0099560	9.37	GPC4 SLITRK1
6	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	GO:0098696	9.32	GPC4 GPC6
7	glycosaminoglycan biosynthetic process	GO:0006024	9.26	GPC1 GPC3 GPC4 GPC6
8	glycosaminoglycan catabolic process	GO:0006027	8.92	GPC1 GPC3 GPC4 GPC6

Molecular functions related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	GO:1904929	8.62	GPC4 GPC6

Sources

Sources for Body Dysmorphic Disorder

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia