MCID: BRH001
MIFTS: 22

Boerhaave Syndrome

Categories: Gastrointestinal diseases, Rare diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Boerhaave Syndrome

MalaCards integrated aliases for Boerhaave Syndrome:

Name: Boerhaave Syndrome 19 71 33
Boerhaave's Syndrome 19 75
Spontaneous Perforation of the Esophagus 19
Spontaneous Rupture of the Esophagus 19
Rupture of Oesophagus 33
Oesophageal Rupture 33
Ruptured Oesophagus 33
Boerhave Syndrome 19

Classifications:



External Ids:

ICD11 33 1363344947
UMLS 71 C0238115

Summaries for Boerhaave Syndrome

GARD: 19 The occurrence of the full-thickness tear (perforation) of the wall of the esophagus.

MalaCards based summary: Boerhaave Syndrome, also known as boerhaave's syndrome, is related to pneumothorax, primary spontaneous and pneumothorax. Affiliated tissues include smooth muscle, heart and liver.

Related Diseases for Boerhaave Syndrome

Diseases related to Boerhaave Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 pneumothorax, primary spontaneous 10.5
2 pneumothorax 10.5
3 mediastinitis 10.4
4 mallory-weiss syndrome 10.4
5 respiratory failure 10.3
6 pleural empyema 10.3
7 volvulus of midgut 10.1
8 gastroenteritis 10.1
9 muscle hypertrophy 10.1
10 polymyositis 10.1
11 dermatomyositis 10.1
12 asthma 10.1
13 pulmonary disease, chronic obstructive 10.1
14 gastric cancer 10.1
15 pyelonephritis 10.1
16 ehlers-danlos syndrome 10.1
17 intestinal perforation 10.1
18 tracheal stenosis 10.1
19 status asthmaticus 10.1
20 47 xxx syndrome 10.1
21 diabetes mellitus, ketosis-prone 10.1
22 leukemia, acute lymphoblastic 10.1
23 esophagitis 10.1
24 toxic shock syndrome 10.1
25 alcohol use disorder 10.1
26 duodenal ulcer 10.1
27 esophageal disease 10.1
28 diaphragmatic hernia, congenital 10.1
29 aspiration pneumonia 10.1
30 peptic esophagitis 10.1
31 gastrointestinal system disease 10.1
32 acute myocardial infarction 10.1
33 48,xyyy 10.1
34 varicose veins 10.0
35 esophageal varix 10.0
36 alcohol dependence 9.9
37 gastroesophageal reflux 9.9
38 hernia, hiatus 9.9
39 oculodentodigital dysplasia 9.9
40 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 9.9
41 tuberous sclerosis 1 9.9
42 type 1 diabetes mellitus 9.9
43 lymphangioleiomyomatosis 9.9
44 esophagitis, eosinophilic, 1 9.9
45 tuberous sclerosis 2 9.9
46 cardiac arrest 9.9
47 aortic dissection 9.9
48 adult respiratory distress syndrome 9.9
49 head and neck cancer 9.9
50 bronchopneumonia 9.9

Graphical network of the top 20 diseases related to Boerhaave Syndrome:



Diseases related to Boerhaave Syndrome

Symptoms & Phenotypes for Boerhaave Syndrome

Drugs & Therapeutics for Boerhaave Syndrome

Search Clinical Trials, NIH Clinical Center for Boerhaave Syndrome

Genetic Tests for Boerhaave Syndrome

Anatomical Context for Boerhaave Syndrome

Organs/tissues related to Boerhaave Syndrome:

MalaCards : Smooth Muscle, Heart, Liver, Pancreas, Colon, Lung

Publications for Boerhaave Syndrome

Articles related to Boerhaave Syndrome:

(show top 50) (show all 1121)
# Title Authors PMID Year
1
Rare case of high amylase pleural effusion without pancreatitis, oesophageal rupture or malignancy. 62
36343981 2022
2
[Pneumomediastinum and vomiting: Which approach to diagnosis? A case report]. 62
36064640 2022
3
Boerhaave syndrome initially presenting as acute coronary syndrome with systolic total obstruction of myocardial bridge. 62
36278252 2022
4
Small Bowel Obstruction Secondary to Migration of a Fractured Esophageal Stent. 62
36457606 2022
5
Oesophageal rupture after right pneumonectomy: A case report. 62
36314724 2022
6
Spontaneous esophageal perforation within a hiatal hernia: A case report. 62
36030761 2022
7
Atypical Presentation of Boerhaave Syndrome With Hypoxia and Unresponsiveness. 62
36110495 2022
8
Laparoscopic Repair of Spontaneous Esophageal Perforation After Multiple Endoscopic Failures. 62
35967151 2022
9
Presentation of Boerhaave's syndrome as an upper-esophageal perforation associated with a right-sided pleural effusion: A case report. 62
35949820 2022
10
Boerhaave Syndrome: An Unexpected Complication of Diabetic Ketoacidosis. 62
35755500 2022
11
It Is Not a Boerhaave! A Case of Spontaneous Pneumothorax. 62
35746987 2022
12
Three Cases of Boerhaave's Syndrome Treated via Laparoscopic Transhiatal Esophageal Repair. 62
35949239 2022
13
Boerhaave Syndrome: A Report of Two Cases and Literature Review. 62
35755521 2022
14
Prolonged Emesis Causing Esophageal Perforation: A Case Report. 62
35673315 2022
15
Above and Below the Diaphragm: A Previously Undescribed Case of Recurrent Boerhaave Syndrome Diagnosed With Computerized Tomography Esophagram. 62
35547434 2022
16
Boerhaave's Syndrome: A Case Report. 62
35530901 2022
17
[Laparoscopic transchiatal access in Boerhaave syndrome]. 62
36073589 2022
18
Outcomes after hybrid minimally invasive treatment of Boerhaave syndrome: a single-institution experience. 62
35020548 2022
19
Subtotal esophagectomy followed by subtotal gastric reconstruction for Boerhaave's syndrome: Case report with literature review. 62
34959089 2022
20
Boerhaave syndrome presenting black pleural effusion: A case report. 62
36408483 2022
21
Boerhaave's Syndrome. 62
34219113 2022
22
Current status of surgical treatment of Boerhaave's syndrome. 62
34117586 2022
23
Transhiatal esophagectomy in Boerhaave syndrome - Case report and literature review. 62
34775326 2021
24
Endoluminal vacuum therapy in the management of an esophago-pleural fistula as a complication of Boerhaave syndrome in a patient with eosinophilic esophagitis. 62
34930127 2021
25
Cyanoacrylate injection treatment for postoperative leakage of Boerhaave's syndrome: A case report. 62
34889255 2021
26
Spontaneous Esophageal Perforation in an Infant: A Rare Case. 62
34692464 2021
27
Minimally Invasive Approach in Boerhaave's Syndrome: Case Series and Systematic Review. 62
33400893 2021
28
'Diagnosis of Boerhaave's Syndrome With Aid of Bedside Ultrasound. 62
34193358 2021
29
Diagnostic challenge and surgical management of Boerhaave's syndrome: a case series. 62
34749789 2021
30
Bovine xenograft pericardial patch use for definitive single stage repair of a large esophageal defect: a case report. 62
34645503 2021
31
Boerhaave syndrome. 62
34580144 2021
32
Boerhaave's syndrome with rupture of the right wall of the esophagus after oral administration of sulfate solution. 62
33393326 2021
33
Successful Late Endoscopic Stent-Grafting in a Patient with Boerhaave Syndrome. 62
34385411 2021
34
Unusual Presentation of COVID Pneumonia as Esophageal Rupture Ended With Successful Management. 62
34567889 2021
35
A rare endoscopic image of Boerhaave syndrome in a patient treated with pleural effusion drainage. 62
34018707 2021
36
Management of Boerhaave syndrome in Australasia: a retrospective case series and systematic review of the Australasian literature. 62
33319446 2021
37
Clinical features of idiopathic esophageal perforation compared with typical post-emetic type: a newly proposed subtype in Boerhaave's syndrome. 62
33386506 2021
38
Boerhaave's syndrome: A case of spontaneous oesophageal rupture. 62
34782544 2021
39
Spontaneous Intramural Esophageal Hematoma Secondary to Thrombolysis in the Setting of Pulmonary Embolism. 62
33550927 2021
40
Finding the bubble: atypical and unusual extrapulmonary air in the chest. 62
34246426 2021
41
Alternative management of delayed spontaneous oesophageal perforation by endoscopic stenting. 62
34257131 2021
42
Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta-analysis. 62
32681374 2021
43
Oesophageal rupture from a pneumatic blast injury: an unusual mechanism of blunt oesophageal trauma. 62
34116992 2021
44
Usefulness of lavage and drainage using video-assisted thoracoscopic surgery for Boerhaave's syndrome: a retrospective analysis. 62
34277038 2021
45
VACStent: Combining the benefits of endoscopic vacuum therapy and covered stents for upper gastrointestinal tract leakage. 62
34079885 2021
46
Endoscopic negative pressure therapy (ENPT) of a spontaneous oesophageal rupture (Boerhaave's syndrome) with peritonitis - a new treatment option. 62
34589575 2021
47
Third time recurrent Boerhaave's syndrome: a case report. 62
33933141 2021
48
Survival of Boerhaave syndrome against all odds at a rural Emergency Department. 62
33818536 2021
49
Salvage Intraluminal Endoscopic Vacuum Therapy for Stent Failure in Late-Presenting Boerhaave Syndrome. 62
32147589 2021
50
Spontaneous esophageal perforation (Boerhaave syndrome). 62
32456779 2021

Variations for Boerhaave Syndrome

Expression for Boerhaave Syndrome

Search GEO for disease gene expression data for Boerhaave Syndrome.

Pathways for Boerhaave Syndrome

GO Terms for Boerhaave Syndrome

Sources for Boerhaave Syndrome

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....