MCID: BRH001
MIFTS: 18

Boerhaave Syndrome

Categories: Rare diseases

Aliases & Classifications for Boerhaave Syndrome

MalaCards integrated aliases for Boerhaave Syndrome:

Name: Boerhaave Syndrome 52 71
Spontaneous Perforation of the Esophagus 52
Spontaneous Rupture of the Esophagus 52
Boerhaave's Syndrome 52
Boerhave Syndrome 52

Classifications:



External Ids:

UMLS 71 C0238115

Summaries for Boerhaave Syndrome

MalaCards based summary : Boerhaave Syndrome, also known as spontaneous perforation of the esophagus, is related to pneumothorax and mediastinitis. Affiliated tissues include colon and liver.

Related Diseases for Boerhaave Syndrome

Diseases related to Boerhaave Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
# Related Disease Score Top Affiliating Genes
1 pneumothorax 10.4
2 mediastinitis 10.4
3 respiratory failure 10.3
4 mallory-weiss syndrome 10.3
5 esophagitis, eosinophilic, 1 10.2
6 pleural empyema 10.2
7 volvulus of midgut 10.2
8 myocardial infarction 10.2
9 gastroenteritis 10.2
10 48,xyyy 10.2
11 dysphagia 10.2
12 varicose veins 10.2
13 esophageal varix 10.2
14 leukemia, acute lymphoblastic 10.1
15 cardiac arrest 10.1
16 toxic shock syndrome 10.1
17 47,xyy 10.1
18 back pain 10.1
19 aspiration pneumonia 10.1
20 acute myocardial infarction 10.1
21 virus-associated trichodysplasia spinulosa 10.1
22 alcohol dependence 10.0
23 hernia, hiatus 10.0
24 tuberous sclerosis 1 10.0
25 lymphangioleiomyomatosis 10.0
26 diabetes mellitus, ketosis-prone 10.0
27 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.0
28 aortic dissection 10.0
29 esophagitis 10.0
30 bronchopneumonia 10.0
31 pyloric stenosis 10.0
32 tuberous sclerosis 10.0
33 candidiasis 10.0
34 alcohol use disorder 10.0
35 duodenal ulcer 10.0
36 adenocarcinoma 10.0
37 aortic aneurysm 10.0
38 systemic scleroderma 10.0
39 esophageal disease 10.0
40 peptic ulcer disease 10.0
41 peptic ulcer perforation 10.0
42 muscular atrophy 10.0
43 intestinal obstruction 10.0
44 ileus 10.0
45 hypopharynx cancer 10.0
46 subacute delirium 10.0
47 gas gangrene 10.0
48 achalasia 10.0
49 pulmonary embolism 10.0
50 aneurysm 10.0

Graphical network of the top 20 diseases related to Boerhaave Syndrome:



Diseases related to Boerhaave Syndrome

Symptoms & Phenotypes for Boerhaave Syndrome

Drugs & Therapeutics for Boerhaave Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A 75 Year Old With Dyspnea a Case Report.Observational Study Completed NCT00422760

Search NIH Clinical Center for Boerhaave Syndrome

Genetic Tests for Boerhaave Syndrome

Anatomical Context for Boerhaave Syndrome

MalaCards organs/tissues related to Boerhaave Syndrome:

40
Colon, Liver

Publications for Boerhaave Syndrome

Articles related to Boerhaave Syndrome:

(show top 50) (show all 516)
# Title Authors PMID Year
1
Spontaneous esophageal perforation (Boerhaave syndrome). 61
32456779 2020
2
Renal colic causing Boerhaave syndrome. 61
32420192 2020
3
Salvage Intraluminal Endoscopic Vacuum Therapy for Stent Failure in Late-Presenting Boerhaave Syndrome. 61
32147589 2020
4
Esophageal perforation in eosinophilic esophagitis: A systematic review on clinical presentation, management and outcomes. 61
31836305 2020
5
Food poisoning: an underestimated cause of Boerhaave syndrome. 61
31650469 2020
6
Spontaneous Esophageal Rupture or Boerhaave's Syndrome. 61
31976387 2020
7
Challenges in the diagnosis of Boerhaave syndrome: A case report. 61
31914100 2020
8
Candida Empyema as a Red Flag for Esophageal Rupture: A Case Report and Literature Review. 61
32351745 2020
9
Pathophysiology of Vomiting and Esophageal Perforation in Boerhaave's Syndrome. 61
31965389 2020
10
Use of multiple covered metal esophageal stents for treatment of Boerhaave syndrome in achalasia. 61
31844817 2019
11
Over-the-scope-clip: Endoscopic treatment of Boerhaave syndrome. 61
31405533 2019
12
Boerhaave Syndrome Causing Bilateral Empyemas. 61
31750375 2019
13
Boerhaave's syndrome with late presentation. Experience in an Argentine single center: Case series. 61
31367374 2019
14
Boerhaave syndrome: A rare postoperative complication. 61
31348107 2019
15
Aorto-oesophageal fistula: a late complication of Boerhaave syndrome. 61
31278198 2019
16
Facial swelling and dysphonia during labour: a case of Hamman's syndrome. 61
31248891 2019
17
Poorly Differentiated Biliary Adenocarcinoma Leading to Boerhaave syndrome: A Case Report and Review of the Literature. 61
31308042 2019
18
Sepsis in Acute Mediastinitis - A Severe Complication after Oesophageal Perforations. A Review of the Literature. 61
31161141 2019
19
Boerhaave syndrome presenting as gastric emphysema. 61
30316453 2019
20
Successful Treatment Using Endoluminal Vacuum Therapy after Failure of Primary Closure in Boerhaave Syndrome. 61
31030459 2019
21
Boerhaave syndrome treated with endoscopic suturing. 61
30899888 2019
22
Cervical Emphysema in Boerhaave Syndrome. 61
31056087 2019
23
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report. 61
30782160 2019
24
Long-Term Quality of Life Assessment After Successful Endoscopic Vacuum Therapy of Defects in the Upper Gastrointestinal Tract Quality of Life After EVT. 61
30430432 2019
25
[Spontaneous rupture of the esophagus in a patient with chronic obstructive pulmonary disease]. 61
31532175 2019
26
Abrupt Severe Chest Pain and Vomiting: Remember to Think of a Ruptured Oesophagus (Boerhaave Syndrome). 61
31742203 2019
27
Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report. 61
30544378 2018
28
A minimally invasive approach with a 3d imaging system for the treatment of esophageal perforation due to Boerhaave syndrome. 61
30569908 2018
29
Boerhaave Syndrome. 61
30398574 2018
30
Boerhaave syndrome in an elderly man successfully treated with 3-month indwelling esophageal stent. 61
30228849 2018
31
Intrathoracic transmural esophageal perforation (Boerhaave syndrome): Challenges in management of the delayed presentation: Retraction. 61
30142106 2018
32
Multimodal Treatment Strategies for Esophageal Perforation. 61
29975355 2018
33
Primary and Rescue Endoluminal Vacuum Therapy in the Management of Esophageal Perforations and Leaks. 61
29877217 2018
34
A rare complication of ileostomy obstruction: Boerhaave syndrome. 61
30112937 2018
35
Regulating migration of esophageal stents - management using a Sengstaken-Blakemore tube: A case report and review of literature. 61
30065565 2018
36
Boerhaave syndrome: Challenges in diagnosis and treatment of the early presentation and its complication. 61
29443861 2018
37
Boerhaave Syndrome - over 290 years of surgical experiences. Can the disorder recur? 61
31243173 2018
38
Boerhaave syndrome due to hypopharyngeal stenosis associated with chemoradiotherapy for hypopharyngeal cancer: a case report. 61
29884971 2018
39
(Re)building the Wall: Recurrent Boerhaave Syndrome Managed by Over-the-Scope Clip and Covered Metallic Stent Placement. 61
28948439 2018
40
Outcome after stenting and débridement for spontaneous esophageal rupture. 61
29523026 2018
41
Treatment of spontaneous esophageal rupture (Boerhaave syndrome) using thoracoscopic surgery and sivelestat sodium hydrate. 61
29850124 2018
42
Herman Boerhaave, the Dutch Hippocrates, a Forgotten Father of Medicine. 61
29559043 2018
43
Role of Endoscopy in the Management of Boerhaave Syndrome. 61
28928355 2018
44
Boerhaave syndrome: a common manifestation of a rare disease. 61
29415361 2018
45
[Boerhaave syndrome: update on physiopathology, diagnosis and early management]. 61
29384279 2018
46
Tension hydropneumothorax as the initial presentation of Boerhaave syndrome. 61
30101056 2018
47
Boerhaave Syndrome in an Elderly Man. 61
30755979 2018
48
Spontaneous Intramural Esophageal Rupture: An Uncommon Presentation of Eosinophilic Esophagitis Requiring Endoscopic Clipping. 61
30280106 2018
49
Barogenic rupture of esophagus (Boerhaave syndrome) as diagnostic and therapeutic challenge requiring rapid and effective interdisciplinary cooperation - case report. 61
29335396 2017
50
Intrathoracic transmural esophageal perforation (Boerhaave syndrome): Challenges in management of the delayed presentation. 61
29073118 2017

Variations for Boerhaave Syndrome

Expression for Boerhaave Syndrome

Search GEO for disease gene expression data for Boerhaave Syndrome.

Pathways for Boerhaave Syndrome

GO Terms for Boerhaave Syndrome

Sources for Boerhaave Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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