MCID: BLV001
MIFTS: 28

Bolivian Hemorrhagic Fever

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Bolivian Hemorrhagic Fever

MalaCards integrated aliases for Bolivian Hemorrhagic Fever:

Name: Bolivian Hemorrhagic Fever 12 73 58 29 15
Hemorrhagic Fever, Bolivian 70
Machupo Hemorrhagic Fever 58

Classifications:

Orphanet: 58  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:0050195
ICD10 32 A96.1
ICD10 via Orphanet 33 A96.1
UMLS via Orphanet 71 C0282192
Orphanet 58 ORPHA319229
UMLS 70 C0282192

Summaries for Bolivian Hemorrhagic Fever

Disease Ontology : 12 A viral infectious disease that is a hemorrhagic fever, has material basis in Machupo virus, which is transmitted by vesper mouse, Calomys callosus. The infection has symptom fever, has symptom headache, has symptom fatigue, has symptom myalgia, has symptom arthralgia, has symptom bleeding from the oral and nasal mucosa, and has symptom bleeding from the bronchopulmonary, gastrointestinal and genitourinary tracts.

MalaCards based summary : Bolivian Hemorrhagic Fever, also known as hemorrhagic fever, bolivian, is related to argentine hemorrhagic fever and hemorrhagic disease, and has symptoms including fatigue, fever and arthralgia. An important gene associated with Bolivian Hemorrhagic Fever is GTPBP1 (GTP Binding Protein 1), and among its related pathways/superpathways is Peginterferon alpha-2a/Peginterferon alpha-2b Pathway (Hepatocyte), Pharmacodynamics.

Wikipedia : 73 Bolivian hemorrhagic fever (BHF), also known as black typhus or Ordog Fever, is a hemorrhagic fever and... more...

Related Diseases for Bolivian Hemorrhagic Fever

Diseases related to Bolivian Hemorrhagic Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 argentine hemorrhagic fever 30.5 TFRC MBTPS1 GTPBP1 GP2 ERVW-1 DDX58
2 hemorrhagic disease 28.9 STAT1 GTPBP1 GP2 ERVW-1 DDX58
3 blessig's cysts 10.2 GTPBP1 GP2
4 exanthem 10.2
5 thrombocytopenia 10.2
6 tremor 10.2
7 de quervain disease 10.2 GTPBP1 GP2
8 marburg hemorrhagic fever 10.2 GTPBP1 GP2
9 articulation disorder 10.2 GTPBP1 GP2
10 alzheimer disease 5 10.1 GTPBP1 DDX58
11 meningoencephalitis 10.1
12 disseminated intravascular coagulation 10.1
13 neutropenia 10.1
14 bronchopneumonia 10.1
15 central nervous system disease 10.1
16 lymphopenia 10.1
17 nervous system disease 10.1
18 splenomegaly 10.1
19 viral hemorrhagic fever 10.1
20 swine influenza 10.1 GP2 DDX58
21 crimean-congo hemorrhagic fever 10.0 MBTPS1 DDX58
22 lymphocytic choriomeningitis 10.0 DDX58 DAG1
23 zika fever 10.0 ERVW-1 DDX58
24 gray platelet syndrome 10.0 GTPBP1 GP2
25 hantavirus hemorrhagic fever with renal syndrome 10.0 ERVW-1 DDX58
26 congenital disorder of glycosylation, type iin 10.0 OSTC OST4
27 vulto-van silfhout-de vries syndrome 9.9 GTPBP1 GP2 ERVW-1
28 coronavirus infectious disease 9.9 ERVW-1 DDX58
29 stuttering 9.9 GTPBP1 GP2
30 brazilian hemorrhagic fever 9.8 MBTPS1 GTPBP1 GP2 DAG1
31 venezuelan hemorrhagic fever 9.8 MBTPS1 GTPBP1 GP2 DAG1
32 combined t and b cell immunodeficiency 9.8 TFRC STAT1
33 sting-associated vasculopathy with onset in infancy 9.8 STAT1 DDX58
34 microphthalmia with limb anomalies 9.7 STAT1 DDX58
35 japanese encephalitis 9.7 STAT1 DDX58
36 chikungunya 9.7 STAT1 DDX58
37 ebola hemorrhagic fever 9.7 GTPBP1 GP2 ERVW-1 DDX58
38 yellow fever 9.6 STAT1 DDX58
39 viral infectious disease 9.5 STAT1 ERVW-1 DDX58
40 human immunodeficiency virus type 1 9.5 TFRC STAT1 ERVW-1
41 lassa fever 9.3 MBTPS1 GTPBP1 GP2 ERVW-1 DDX58 DAG1

Graphical network of the top 20 diseases related to Bolivian Hemorrhagic Fever:



Diseases related to Bolivian Hemorrhagic Fever

Symptoms & Phenotypes for Bolivian Hemorrhagic Fever

Symptoms:

12
  • fatigue
  • fever
  • arthralgia
  • myalgia
  • headache
  • bleeding from the
  • bleeding from the bronchopulmonary

Drugs & Therapeutics for Bolivian Hemorrhagic Fever

Search Clinical Trials , NIH Clinical Center for Bolivian Hemorrhagic Fever

Genetic Tests for Bolivian Hemorrhagic Fever

Genetic tests related to Bolivian Hemorrhagic Fever:

# Genetic test Affiliating Genes
1 Bolivian Hemorrhagic Fever 29

Anatomical Context for Bolivian Hemorrhagic Fever

Publications for Bolivian Hemorrhagic Fever

Articles related to Bolivian Hemorrhagic Fever:

(show top 50) (show all 52)
# Title Authors PMID Year
1
Bolivian hemorrhagic fever: A narrative review. 61
33640478 2021
2
Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein. 61
31801871 2020
3
Description and characterization of a novel live-attenuated tri-segmented Machupo virus in Guinea pigs. 61
29879985 2018
4
An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection. 61
28680057 2017
5
The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor. 61
27580122 2016
6
Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic. 61
26581982 2016
7
Pathogenesis of Bolivian Hemorrhagic Fever in Guinea Pigs. 61
26139838 2016
8
Research efforts to control highly pathogenic arenaviruses: a summary of the progress and gaps. 61
25549822 2015
9
Pathology of experimental Machupo virus infection, Chicava strain, in cynomolgus macaques (Macaca fascicularis) by intramuscular and aerosol exposure. 61
24990481 2015
10
A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of Machupo virus. 61
25031335 2014
11
Epidemiology and pathogenesis of Bolivian hemorrhagic fever. 61
24636947 2014
12
Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice. 61
24284323 2014
13
[Bolivian hemorrhagic fever]. 61
24000605 2013
14
A STAT-1 knockout mouse model for Machupo virus pathogenesis. 61
21672221 2011
15
Conserved residues in Lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoprotein. 61
21228230 2011
16
[Chemotherapy for Bolivian hemorrhagic fever in experimentally infected guinea pigs]. 61
20030281 2009
17
Reemergence of Bolivian hemorrhagic fever, 2007-2008. 61
19788833 2009
18
[Use of guinea pigs to evaluate the efficacy of a heterological immunoglobulin against Bolivian hemorrhagic fever]. 61
19708556 2009
19
Genetic diversity among Bolivian arenaviruses. 61
19041349 2009
20
Models for an arenavirus infection in a rodent population: consequences of horizontal, vertical and sexual transmission. 61
19278272 2008
21
Natural nidality in Bolivian hemorrhagic fever and the systematics of the reservoir species. 61
12798015 2002
22
Risks and prevention of nosocomial transmission of rare zoonotic diseases. 61
11170953 2001
23
Treatment of Bolivian hemorrhagic fever with intravenous ribavirin. 61
9145749 1997
24
[Viral hemorrhagic fevers: what is the risk for travelers?]. 61
9612763 1997
25
[The study of protective properties of attenuated strain of Argentinian hemorrhagic fever]. 61
8999669 1996
26
[Experimental study of the possibility of emergency prophylaxis of Bolivian hemorrhagic fever]. 61
8659175 1995
27
Prospects for the control of Bolivian hemorrhagic fever. 61
8903174 1995
28
Bolivian hemorrhagic fever reappears. 61
7640699 1995
29
From the Centers for Disease Control and Prevention. Bolivian hemorrhagic fever--El Beni Department, Bolivia, 1994. 61
7807656 1995
30
Bolivian hemorrhagic fever--El Beni Department, Bolivia, 1994. 61
7990799 1994
31
Re-emergence of Bolivian hemorrhagic fever. 61
7703000 1994
32
Molecular approaches for the treatment of hemorrhagic fever virus infections. 61
8250543 1993
33
[Present status of zoonotic hemorrhagic fevers of South America]. 61
7819800 1993
34
The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase. 61
2705303 1989
35
Indirect immunofluorescence, serum neutralization, and viremia responses of rhesus monkeys (Macaca mulatta) to Machupo virus. 61
3014062 1986
36
[Bolivian hemorrhagic fever: epidemiology, symptomatology, management and prognosis]. 61
6248659 1980
37
Studies of the coagulation system and blood pressure during experimental Bolivian hemorrhagic fever in rhesus monkeys. 61
103447 1978
38
Pathology of Bolivian Hemorrhagic fever in the African green monkey. 61
99059 1978
39
The African green monkey as an alternate primate host for studying Machupo virus infection. 61
402863 1977
40
Pathology of chronic Bolivian hemorrhagic fever in the rhesus monkey. 61
181994 1976
41
A rhesus monkey model for the study of Bolivian hemorrhagic fever. 61
173762 1976
42
Pathology of Bolivian hemorrhagic fever in the rhesus monkey. 61
4202335 1973
43
Comparative histopathology of two strains of Bolivian hemorrhagic fever virus infections in suckling hamsters. 61
4745242 1973
44
The measurement of specific antibodies in Bolivian hemorrhagic fever by neutralization of virus plaques. 61
4975291 1969
45
Multiplication of Machupo virus, the etiological agent of Bolivian hemorrhagic fever, in cell cultures. 61
5765269 1969
46
Acidophilic bodies. Their chemical and physical nature in patients with Bolivian hemorrhagic fever. 61
4169327 1968
47
On the mode of transmission of Bolivian hemorrhagic fever. 61
5301560 1967
48
Some characteristics of Machupo virus, causative agent of Bolivian hemorrhagic fever. 61
4378149 1967
49
Bolivian hemorrhagic fever. A pathologic description. 61
6023050 1967
50
Bolivian hemorrhagic fever. 61
6071501 1967

Variations for Bolivian Hemorrhagic Fever

Expression for Bolivian Hemorrhagic Fever

Search GEO for disease gene expression data for Bolivian Hemorrhagic Fever.

Pathways for Bolivian Hemorrhagic Fever

Pathways related to Bolivian Hemorrhagic Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
9.98 STAT1 DDX58

GO Terms for Bolivian Hemorrhagic Fever

Cellular components related to Bolivian Hemorrhagic Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.61 TFRC OSTC OST4 MBTPS1 GTPBP1 GP2
2 oligosaccharyltransferase complex GO:0008250 8.62 OSTC OST4

Biological processes related to Bolivian Hemorrhagic Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to peptide hormone GO:0043434 9.32 STAT1 DAG1
2 positive regulation of defense response to virus by host GO:0002230 9.26 STAT1 DDX58
3 viral process GO:0016032 9.26 TFRC STAT1 DDX58 DAG1
4 protein N-linked glycosylation via asparagine GO:0018279 9.16 OSTC OST4
5 positive regulation of interferon-alpha production GO:0032727 8.62 STAT1 DDX58

Sources for Bolivian Hemorrhagic Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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