MCID: BNN002
MIFTS: 20

Bone Angioendothelial Sarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Bone Angioendothelial Sarcoma

MalaCards integrated aliases for Bone Angioendothelial Sarcoma:

Name: Bone Angioendothelial Sarcoma 12 15
Osseous Hemangiosarcoma 12
Bone Angiosarcoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3351
NCIt 49 C6479
UMLS 71 C1332574

Summaries for Bone Angioendothelial Sarcoma

MalaCards based summary : Bone Angioendothelial Sarcoma, also known as osseous hemangiosarcoma, is related to angiosarcoma and spindle cell synovial sarcoma, and has symptoms including pain An important gene associated with Bone Angioendothelial Sarcoma is COPS3 (COP9 Signalosome Subunit 3), and among its related pathways/superpathways is Transcriptional misregulation in cancer. Affiliated tissues include bone, skeletal muscle and kidney, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Bone Angioendothelial Sarcoma

Graphical network of the top 20 diseases related to Bone Angioendothelial Sarcoma:



Diseases related to Bone Angioendothelial Sarcoma

Symptoms & Phenotypes for Bone Angioendothelial Sarcoma

UMLS symptoms related to Bone Angioendothelial Sarcoma:


pain

GenomeRNAi Phenotypes related to Bone Angioendothelial Sarcoma according to GeneCards Suite gene sharing:

26 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.95 SSX1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.95 SSX4 SSX4B SSX1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.95 SSX4 SSX4B
4 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.95 SSX1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.95 SSX4 SSX4B
6 Increased shRNA abundance (Z-score > 2) GR00366-A-51 9.95 SSX4 SSX4B
7 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.95 SSX1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.95 SSX1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.95 SSX4 SSX4B
10 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.95 SSX1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-82 9.95 SSX4 SSX4B
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.43 SSX4 SSX4B
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.43 SSX4 SSX4B
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.43 SSX4 SSX4B

Drugs & Therapeutics for Bone Angioendothelial Sarcoma

Search Clinical Trials , NIH Clinical Center for Bone Angioendothelial Sarcoma

Genetic Tests for Bone Angioendothelial Sarcoma

Anatomical Context for Bone Angioendothelial Sarcoma

MalaCards organs/tissues related to Bone Angioendothelial Sarcoma:

40
Bone, Skeletal Muscle, Kidney, Lung

Publications for Bone Angioendothelial Sarcoma

Articles related to Bone Angioendothelial Sarcoma:

# Title Authors PMID Year
1
Survival Analysis of Patients with Osseous Malignant Vascular Tumors: Results of the Surveillance, Epidemiology, and End Results (SEER) Database from 1973 to 2015. 61
31344019 2019
2
Multicentric osseous hemangiosarcoma in a Chianina-Angus steer. 61
7193377 1981

Variations for Bone Angioendothelial Sarcoma

Expression for Bone Angioendothelial Sarcoma

Search GEO for disease gene expression data for Bone Angioendothelial Sarcoma.

Pathways for Bone Angioendothelial Sarcoma

Pathways related to Bone Angioendothelial Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.89 SSX1 SS18

GO Terms for Bone Angioendothelial Sarcoma

Cellular components related to Bone Angioendothelial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular GO:0005622 8.8 SSX4B SSX4 SSX1

Molecular functions related to Bone Angioendothelial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleic acid binding GO:0003676 8.8 SSX4B SSX4 SSX1

Sources for Bone Angioendothelial Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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