MCID: BNC005
MIFTS: 21

Bone Chondrosarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Bone Chondrosarcoma

MalaCards integrated aliases for Bone Chondrosarcoma:

Name: Bone Chondrosarcoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050897

Summaries for Bone Chondrosarcoma

Disease Ontology : 12 A chondrosarcoma that is located in bone.

MalaCards based summary : Bone Chondrosarcoma is related to chondrosarcoma and cartilage disease. An important gene associated with Bone Chondrosarcoma is COMP (Cartilage Oligomeric Matrix Protein), and among its related pathways/superpathways are Degradation of the extracellular matrix and Parathyroid hormone synthesis, secretion and action. Affiliated tissues include bone and bone.

Related Diseases for Bone Chondrosarcoma

Graphical network of the top 20 diseases related to Bone Chondrosarcoma:



Diseases related to Bone Chondrosarcoma

Symptoms & Phenotypes for Bone Chondrosarcoma

Drugs & Therapeutics for Bone Chondrosarcoma

Search Clinical Trials , NIH Clinical Center for Bone Chondrosarcoma

Genetic Tests for Bone Chondrosarcoma

Anatomical Context for Bone Chondrosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Bone Chondrosarcoma:

20
Bone

MalaCards organs/tissues related to Bone Chondrosarcoma:

42
Bone

Publications for Bone Chondrosarcoma

Articles related to Bone Chondrosarcoma:

(showing 2, show less)
# Title Authors Year
1
Temporal bone chondrosarcoma: Presentation of 4 cases and review of the literature. ( 25531842 )
2014
2
Primary multipotential malignant neoplasm of bone: chondrosarcoma associated with squamous cell carcinoma. ( 2419240 )
1986

Variations for Bone Chondrosarcoma

Expression for Bone Chondrosarcoma

Search GEO for disease gene expression data for Bone Chondrosarcoma.

Pathways for Bone Chondrosarcoma

GO Terms for Bone Chondrosarcoma

Cellular components related to Bone Chondrosarcoma according to GeneCards Suite gene sharing:

(showing 4, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 ACAN COMP CTSD MMP13
2 lysosomal lumen GO:0043202 9.16 ACAN CTSD
3 extracellular matrix GO:0031012 9.13 ACAN COMP MMP13
4 collagen-containing extracellular matrix GO:0062023 8.8 ACAN COMP CTSD

Biological processes related to Bone Chondrosarcoma according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.54 ACAN CTSD MMP13
2 collagen catabolic process GO:0030574 9.32 CTSD MMP13
3 endochondral ossification GO:0001958 9.26 MMP13 RUNX2
4 chondrocyte development GO:0002063 9.16 ACAN RUNX2
5 skeletal system development GO:0001501 9.13 ACAN COMP RUNX2
6 growth plate cartilage development GO:0003417 8.62 COMP MMP13

Molecular functions related to Bone Chondrosarcoma according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 9.16 ACAN COMP
2 calcium ion binding GO:0005509 9.13 ACAN COMP MMP13
3 collagen binding GO:0005518 8.62 COMP MMP13

Sources for Bone Chondrosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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