MCID: BNP002
MIFTS: 26

Bone Epithelioid Hemangioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Bone Epithelioid Hemangioma

MalaCards integrated aliases for Bone Epithelioid Hemangioma:

Name: Bone Epithelioid Hemangioma 12 15 17 74
Bone Hemangioma 12 74
Osseous Epithelioid Hemangioma 12
Hemangioma of Bone 12
Osseous Hemangioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6610
NCIt 51 C5396 C6477

Summaries for Bone Epithelioid Hemangioma

MalaCards based summary : Bone Epithelioid Hemangioma, also known as bone hemangioma, is related to hemangioma and kaposiform hemangioendothelioma. An important gene associated with Bone Epithelioid Hemangioma is NFATC1 (Nuclear Factor Of Activated T Cells 1), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and NF-kappaB Signaling. Affiliated tissues include bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Bone Epithelioid Hemangioma

Diseases related to Bone Epithelioid Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 hemangioma 30.2 CD34 PECAM1
2 kaposiform hemangioendothelioma 10.1 CD34 PECAM1
3 erythema elevatum diutinum 10.1 CD34 PECAM1
4 vulvar sarcoma 10.0 CD34 EWSR1
5 mesenchymal cell neoplasm 10.0 CD34 EWSR1
6 skin sarcoma 10.0 CD34 EWSR1
7 zika fever 10.0 EWSR1 F3
8 muscle cancer 9.9 CD34 EWSR1
9 spleen angiosarcoma 9.9 CD34 SMUG1
10 tibial adamantinoma 9.9 CD34 SMUG1
11 liposarcoma 9.9 CD34 EWSR1
12 sternum cancer 9.9 CD34 SMUG1
13 angiosarcoma 9.9
14 breast leiomyosarcoma 9.9 CD34 SMUG1
15 malignant epithelioid hemangioendothelioma 9.9 CD34 SMUG1
16 eccrine adenocarcinoma 9.9 CD34 SMUG1
17 klippel-trenaunay-weber syndrome 9.8
18 nervous system cancer 9.8 CD34 EWSR1
19 breast angiosarcoma 9.8 CD34 SMUG1
20 partial motor epilepsy 9.8 F3 SMUG1
21 malignant hemangioma 9.8 CD34 SMUG1
22 pediatric lymphoma 9.8 CD34 SMUG1
23 lymphangiosarcoma 9.8 CD34 SMUG1
24 lemierre's syndrome 9.8 F3 SMUG1
25 endocardium disease 9.8 F3 SMUG1
26 leukocyte disease 9.7 CD34 SMUG1
27 nevus, epidermal 9.7
28 osteomalacia 9.7
29 rickets 9.7
30 histiocytoid hemangioma 9.7
31 hemangioendothelioma 9.7
32 hereditary hypophosphatemic rickets 9.7
33 facial paralysis 9.7
34 gastrointestinal system cancer 9.6 CD34 SMUG1
35 connective tissue cancer 9.6 CD34 EWSR1 SMUG1
36 muscular disease 9.6 CD34 EWSR1 SMUG1
37 meningioma, familial 9.5 CD34 SMUG1

Graphical network of the top 20 diseases related to Bone Epithelioid Hemangioma:



Diseases related to Bone Epithelioid Hemangioma

Symptoms & Phenotypes for Bone Epithelioid Hemangioma

GenomeRNAi Phenotypes related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

27 (show all 20)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.7 PECAM1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.7 EWSR1 PECAM1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.7 PECAM1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.7 EWSR1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.7 PECAM1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.7 EWSR1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.7 EWSR1 PECAM1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.7 EWSR1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.7 EWSR1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.7 EWSR1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.7 EWSR1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.7 PECAM1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.7 PECAM1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.7 PECAM1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.7 EWSR1 PECAM1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.7 EWSR1 PECAM1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.7 PECAM1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.7 EWSR1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.7 EWSR1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.7 EWSR1

MGI Mouse Phenotypes related to Bone Epithelioid Hemangioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 CD34 F3 NFATC1 PECAM1 SMUG1

Drugs & Therapeutics for Bone Epithelioid Hemangioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epithelioid Hemangioma of Bone And Soft Tissue Completed NCT03169595

Search NIH Clinical Center for Bone Epithelioid Hemangioma

Genetic Tests for Bone Epithelioid Hemangioma

Anatomical Context for Bone Epithelioid Hemangioma

MalaCards organs/tissues related to Bone Epithelioid Hemangioma:

42
Bone

Publications for Bone Epithelioid Hemangioma

Articles related to Bone Epithelioid Hemangioma:

# Title Authors Year
1
Frontal Bone Hemangioma in an 8-year-old Female: A Common Tumor in a Rare Location. ( 28163515 )
2016
2
A rare case of parietal bone hemangioma. ( 27365969 )
2016
3
Temporal bone hemangioma as a cause of facial paralysis. ( 10089691 )
1999

Variations for Bone Epithelioid Hemangioma

Expression for Bone Epithelioid Hemangioma

Search GEO for disease gene expression data for Bone Epithelioid Hemangioma.

Pathways for Bone Epithelioid Hemangioma

Pathways related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 CD34 PECAM1
2 11.31 CD34 NFATC1 PECAM1
3 11.16 F3 NFATC1
4 10.91 F3 PECAM1

GO Terms for Bone Epithelioid Hemangioma

Cellular components related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 PECAM1

Biological processes related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of angiogenesis GO:0045766 8.96 CD34 F3
2 glomerular endothelium development GO:0072011 8.62 CD34 PECAM1

Sources for Bone Epithelioid Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....