MCID: BNP002
MIFTS: 23

Bone Epithelioid Hemangioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Bone Epithelioid Hemangioma

MalaCards integrated aliases for Bone Epithelioid Hemangioma:

Name: Bone Epithelioid Hemangioma 12 15 17 71
Bone Hemangioma 12 71
Osseous Epithelioid Hemangioma 12
Hemangioma of Bone 12
Osseous Hemangioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6610
NCIt 49 C5396 C6477
UMLS 71 C1332575 C1332578

Summaries for Bone Epithelioid Hemangioma

MalaCards based summary : Bone Epithelioid Hemangioma, also known as bone hemangioma, is related to mesenchymal cell neoplasm and histiocytoid hemangioma. An important gene associated with Bone Epithelioid Hemangioma is PATZ1 (POZ/BTB And AT Hook Containing Zinc Finger 1). Affiliated tissues include bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Bone Epithelioid Hemangioma

Diseases related to Bone Epithelioid Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 mesenchymal cell neoplasm 29.6 PECAM1 EWSR1
2 histiocytoid hemangioma 10.1
3 vulvar sarcoma 10.0 ZNF444 EWSR1
4 sweat gland benign neoplasm 10.0 ZNF444 EWSR1
5 myoepithelial carcinoma 10.0 ZNF444 EWSR1
6 angiosarcoma 10.0
7 hemangioma 10.0
8 hemangioendothelioma 10.0
9 epithelioid hemangioendothelioma 10.0
10 sweat gland disease 10.0 ZNF444 EWSR1
11 cardiovascular cancer 9.9 PECAM1 EWSR1
12 glomangiosarcoma 9.9 ZNF444 PECAM1
13 connective tissue benign neoplasm 9.9 PECAM1 EWSR1
14 hypophosphatemia 9.9
15 osteomalacia 9.9
16 vascular cancer 9.9
17 facial paralysis 9.9
18 klippel-trenaunay-weber syndrome 9.9
19 new daily-persistent headache 9.9
20 headache 9.9
21 fibrous histiocytoma 9.8 PECAM1 EWSR1
22 myoepithelioma 9.8 ZNF444 PBX3 EWSR1
23 extraskeletal ewing sarcoma 9.8 SMARCA5 EWSR1
24 nevus, epidermal 9.7
25 renal glucosuria 9.7
26 bone disease 9.7
27 malignant hemangioma 9.7
28 osteomyelitis 9.7
29 rickets 9.7
30 sarcoma 9.7
31 myopathy 9.7
32 spindle cell sarcoma 9.7
33 cavernous hemangioma 9.7
34 hypereosinophilic syndrome 9.7
35 inflammatory linear verrucous epidermal nevus 9.7
36 pyogenic granuloma 9.7
37 hereditary hypophosphatemic rickets 9.7
38 back pain 9.7
39 rare vascular tumor 9.7
40 retiform hemangioendothelioma 9.7
41 hemifacial spasm, familial 9.7
42 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
43 inflammatory spondylopathy 9.7
44 spondylitis 9.7
45 primary bone cancer 9.7
46 hemifacial spasm 9.7
47 rare tumor 9.7
48 glanzmann thrombasthenia 9.6 RAP1A PECAM1
49 extraosseous chondrosarcoma 9.4 ZNF444 PATZ1 NFATC2 EWSR1
50 chondrosarcoma, extraskeletal myxoid 9.2 ZNF444 PBX3 PATZ1 NFATC2 EWSR1

Graphical network of the top 20 diseases related to Bone Epithelioid Hemangioma:



Diseases related to Bone Epithelioid Hemangioma

Symptoms & Phenotypes for Bone Epithelioid Hemangioma

GenomeRNAi Phenotypes related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.72 PECAM1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.72 EWSR1 PECAM1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-119 9.72 NFATC2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.72 PECAM1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.72 PECAM1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-14 9.72 PECAM1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.72 PECAM1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.72 NFATC2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.72 EWSR1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.72 EWSR1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.72 PECAM1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.72 EWSR1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-203 9.72 EWSR1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.72 NFATC2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-211 9.72 PECAM1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.72 PECAM1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.72 EWSR1 PECAM1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.72 PECAM1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.72 PECAM1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-75 9.72 PECAM1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-89 9.72 EWSR1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.72 NFATC2
23 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.72 EWSR1

Drugs & Therapeutics for Bone Epithelioid Hemangioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential Completed NCT03169595

Search NIH Clinical Center for Bone Epithelioid Hemangioma

Genetic Tests for Bone Epithelioid Hemangioma

Anatomical Context for Bone Epithelioid Hemangioma

MalaCards organs/tissues related to Bone Epithelioid Hemangioma:

40
Bone

Publications for Bone Epithelioid Hemangioma

Articles related to Bone Epithelioid Hemangioma:

(show all 28)
# Title Authors PMID Year
1
68Ga DOTATATE Uptake in Hemangioma Simulating Metastasis on PET Imaging: CT helps characterize bone hemangioma that could be wrongly interpreted as skeletal metastases on 68Ga DOTATATE PET imaging. 61
31276092 2019
2
Clinicopathological characteristics of costal hemangiomas: a case report and literature review. 61
30477380 2019
3
[Cavernous hemangioma of the nasal bones: a case report]. 61
30425381 2018
4
Frontal Bone Hemangioma in an 8-year-old Female: A Common Tumor in a Rare Location. 61
28163515 2016
5
A rare case of parietal bone hemangioma. 61
27365969 2016
6
[Primary intraoseous hemangioma of temporal bone]. 61
24835906 2014
7
A surface-based hemangioma of the radius which posed radiological diagnostic difficulties. 61
23544276 2013
8
Cavernous hemangioma of the parietal bone. 61
24133611 2013
9
Surgical techniques for the removal of forehead hemangioma. 61
16877918 2006
10
Reconstruction of intraosseous hemangiomas of the midface using split calvarial bone grafts. 61
16525289 2006
11
Hemangioma of the radius associated with Kasabach-Merritt syndrome: case report and literature review. 61
14676541 2004
12
[Recurring bone epithelioid hemangioma]. 61
12843975 2003
13
Primary hemangioma of the occipital bone in the region of the torcula--two case reports. 61
11902074 2002
14
Solitary osseous hemangioma outside the spinal and craniofacial bones. 61
10853892 2000
15
Temporal bone hemangioma as a cause of facial paralysis. 61
10089691 1999
16
Acquired spinal stenosis secondary to an expanding thoracic vertebral hemangioma. 61
8441948 1993
17
[Infraorbital bone hemangioma]. 61
1515190 1992
18
[Bone hemangioma of the limbs. A report of two cases in children]. 61
1588239 1992
19
[Skeletal scintigraphy in hemangioma of the bones]. 61
3357384 1988
20
[Cavernous hemangioma of the frontal bone]. 61
3785565 1986
21
[Embolization of an extensive soft tissue and bone hemangioma of the left half of the face in childhood: an interesting case]. 61
6970433 1980
22
Hemangioma of the nasal bones: radiographic appearance. 61
655574 1978
23
[A bone hemangioma in the articular process of the mandible]. 61
1058588 1975
24
[Bone hemangioma]. 61
5043689 1972
25
[Clinical aspects and therapy of bone hemangioma of the jaws]. 61
5277030 1970
26
[CONTRIBUTION TO BONE HEMANGIOMA (HEMANGIOMA OF THE RIBS IN POLYOSTOTIC HEMANGIOMA)]. 61
14165994 1964
27
[Cranial bone hemangioma with supra- and infra-tentorial spreading]. 61
5831194 1964
28
[2 Cases of bone hemangioma with rare site & 1 case of specific spondylitis with x-ray resembling hemangioma]. 61
13618973 1958

Variations for Bone Epithelioid Hemangioma

Expression for Bone Epithelioid Hemangioma

Search GEO for disease gene expression data for Bone Epithelioid Hemangioma.

Pathways for Bone Epithelioid Hemangioma

GO Terms for Bone Epithelioid Hemangioma

Biological processes related to Bone Epithelioid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.35 ZNF444 PBX3 PATZ1 NFATC2 EWSR1
2 establishment of endothelial barrier GO:0061028 8.62 RAP1A PECAM1

Sources for Bone Epithelioid Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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