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Bone Fracture

Categories: Bone diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Bone Fracture

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MalaCards integrated aliases for Bone Fracture:

Name: Bone Fracture 39 56 17

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)


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Summaries for Bone Fracture

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MalaCards based summary : Bone Fracture is related to osteofibrous dysplasia and pneumonia. An important gene associated with Bone Fracture is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are Adipogenesis and Th1 Differentiation Pathway. The drugs Ceftaroline fosamil and Teriparatide have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Adipose, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 77 A bone fracture (sometimes abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a... more...

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Related Diseases for Bone Fracture

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Diseases related to Bone Fracture via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 211)
# Related Disease Score Top Affiliating Genes
1 osteofibrous dysplasia 31.3 BGLAP BMP2
2 pneumonia 29.4 CRP TLR4
3 bone resorption disease 29.3 BGLAP BMP2
4 spinal muscular atrophy, type i, with congenital bone fractures 12.7
5 spinal muscular atrophy with congenital bone fractures 2 12.6
6 prenatal-onset spinal muscular atrophy with congenital bone fractures 12.2
7 antley-bixler syndrome without genital anomalies or disordered steroidogenesis 11.4
8 polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 11.2
9 antley-bixler syndrome 11.2
10 hyper-ige recurrent infection syndrome 1, autosomal dominant 11.1
11 osteogenesis imperfecta, type ii 11.1
12 gnathodiaphyseal dysplasia 11.1
13 polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2 11.1
14 marsili syndrome 10.9
15 osteogenesis imperfecta, type i 10.9
16 mucolipidosis iii alpha/beta 10.9
17 multiple pterygium syndrome, lethal type 10.9
18 osteoporosis-pseudoglioma syndrome 10.9
19 pyle disease 10.9
20 spinal muscular atrophy, x-linked 2 10.9
21 lethal congenital contracture syndrome 2 10.9
22 osteogenesis imperfecta, type v 10.9
23 cerebroretinal microangiopathy with calcifications and cysts 1 10.9
24 ewing sarcoma 10.9
25 neuropathy, hereditary sensory and autonomic, type vii 10.9
26 hyper-ige recurrent infection syndrome 3, autosomal recessive 10.9
27 bruck syndrome 10.9
28 rickets 10.9
29 tetanus 10.9
30 osteitis fibrosa 10.9
31 cerebrospinal fluid leak 10.9
32 osteoporosis 10.3
33 facial paralysis 10.3
34 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
35 head injury 10.1
36 lymphadenitis 10.1 STAT3 TLR4
37 brain injury 10.0
38 dental abscess 10.0 CRP TLR4
39 suppurative otitis media 10.0 CRP TLR4
40 pyelitis 10.0 CRP TLR4
41 septic arthritis 10.0 CRP TLR4
42 scrub typhus 10.0 CRP TLR4
43 bacterial sepsis 10.0 CRP TLR4
44 pelvic inflammatory disease 10.0 CRP TLR4
45 perinatal necrotizing enterocolitis 10.0 CRP TLR4
46 extrinsic cardiomyopathy 10.0 CRP TLR4
47 pyelonephritis 10.0 CRP TLR4
48 spinal muscular atrophy 10.0
49 muscular atrophy 10.0
50 brucellosis 10.0 CRP TLR4

Graphical network of the top 20 diseases related to Bone Fracture:



Diseases related to Bone Fracture
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Symptoms & Phenotypes for Bone Fracture

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GenomeRNAi Phenotypes related to Bone Fracture according to GeneCards Suite gene sharing:

27 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.44 BGLAP
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.44 CRP
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-167 9.44 STAT3
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.44 BGLAP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.44 BGLAP CRP STAT3
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-181 9.44 BGLAP
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-187 9.44 STAT3
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.44 STAT3
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.44 STAT3
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.44 CRP
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.44 CRP
Sources

Drugs & Therapeutics for Bone Fracture

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Drugs for Bone Fracture (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 869)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftaroline fosamil Approved, Investigational Phase 4,Phase 1,Phase 2 229016-73-3
2
Teriparatide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 52232-67-4 16133850
3
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 38396-39-3, 2180-92-9 2474
4
Parathyroid hormone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9002-64-6
5
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
6
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1177-87-3
7
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 137-58-6 3676
8
Iron Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable 7439-89-6, 15438-31-0 27284 23925
9
Risedronate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 105462-24-6 5245
10
Etidronic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7414-83-7, 2809-21-4 3305
11
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Not Applicable 1197-18-8 5526
12
Levobupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 27262-47-1 92253
13
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 2078-54-8 4943
14
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 84057-95-4 175805 71273
15
Calcium Carbonate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 471-34-1
16
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 437-38-7 3345
17
Sevoflurane Approved, Vet_approved Phase 4,Phase 2,Not Applicable 28523-86-6 5206
18
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable,Early Phase 1 113775-47-6 5311068 68602
19
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 57-27-2 5288826
20
Cilostazol Approved, Investigational Phase 4,Not Applicable 73963-72-1 2754
21
Clopidogrel Approved Phase 4,Not Applicable 120202-66-6, 113665-84-2 60606
22
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 50-78-2 2244
23
Ketorolac Approved Phase 4,Phase 3,Not Applicable 74103-06-3, 66635-83-4 3826
24
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 329-65-7 838
25
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 76-42-6 5284603
26
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-43-4 5816
27
Cefmetazole Approved, Investigational Phase 4 56796-20-4 42008
28
Celecoxib Approved, Investigational Phase 4,Phase 3,Not Applicable 169590-42-5 2662
29
Silver sulfadiazine Approved, Vet_approved Phase 4,Phase 3 22199-08-2 441244
30
Linagliptin Approved Phase 4 668270-12-0 10096344
31
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
32
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 112809-51-5 3902
33
Zoledronic Acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 118072-93-8 68740
34
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3 73590-58-6 4594
35
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
36
Nitric Oxide Approved Phase 4,Phase 1 10102-43-9 145068
37
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
38
Hydrocortisone Approved, Vet_approved Phase 4,Not Applicable 50-23-7 5754
39
Etomidate Approved Phase 4 33125-97-2 667484 36339
40
Hydrocortisone acetate Approved, Vet_approved Phase 4,Not Applicable 50-03-3
41
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Not Applicable 59467-70-8 4192
42
Alendronate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 66376-36-1, 121268-17-5 2088
43
tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1401-55-4
44
Tocopherol Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 1406-66-2 14986
45
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
46
Perindopril Approved Phase 4 107133-36-8, 82834-16-0 107807
47
Indapamide Approved Phase 4 26807-65-8 3702
48
Emtricitabine Approved, Investigational Phase 4,Phase 2 143491-57-0 60877
49
Tenofovir Approved, Experimental, Investigational Phase 4,Phase 2 147127-20-6 464205
50
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113

Interventional clinical trials:

(show top 50) (show all 3867)
# Name Status NCT ID Phase Drugs
1 Treatment of Intertrochanteric Fracture With New Type of Intramedullary Nail Unknown status NCT01437176 Phase 4
2 Antibiotic Prophylaxis in Open Fractures Unknown status NCT02937181 Phase 4 Ceftaroline
3 Ankle Fractures Treated With Teriparatide Unknown status NCT02955056 Phase 4 Forsteo
4 The Use of Teriparatide as an Adjunctive Therapy for the Treatment of Jones Fractures Unknown status NCT01173081 Phase 4 Teriparatide;Placebo
5 Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture Unknown status NCT00829725 Phase 4
6 NovaLign Intramedullary Fixation System (IFS) for the Treatment of Humeral Fractures Unknown status NCT00969839 Phase 4
7 Obturator and Femoral Nerve Block in Patients With Hip Fracture Unknown status NCT02540837 Phase 4 Bupivacaine;Saline
8 Parathyroid Hormone for the Treatment of Humerus Fractures Unknown status NCT01687374 Phase 4 1-84 parathyroid hormone;Placebo
9 Single Dose of Dexamethasone in Femur Fractures Unknown status NCT01550146 Phase 4 Dexamethasone acetate;Placebo
10 Outcome Comparison Between PFNA and InterTAN Unknown status NCT01797237 Phase 4
11 Hematoma Block for Reduction of Distal Radius Fractures Unknown status NCT02129270 Phase 4 Lidocaine HCl 2% .;Lidocaine HCl 1%
12 The Effect of Liberal vs. Restrictive Transfusion Strategies on Rehabilitation After Hip Fracture Surgery Unknown status NCT00162617 Phase 4 Red blood cell transfusion
13 Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia Unknown status NCT01084122 Phase 4 Iron sucrose
14 Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty Unknown status NCT02148848 Phase 4 Risedronate
15 Comparing Weight Bearing After Intramedullary Fixation Devices for the Proximal Femur Fracture Unknown status NCT01509859 Phase 4
16 W-Shaped Acetabular Angular Plate (WAAP) Versus Reconstruction Plate Unknown status NCT02327949 Phase 4
17 Dose Finding Study for Continuous Spinal Anaesthesia Unknown status NCT01680120 Phase 4
18 Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures Unknown status NCT02580227 Phase 4 Tranexamic Acid
19 A Dose Finding Study for Pain Relief of a Broken Hip Unknown status NCT00926666 Phase 4 Levobupivacaine
20 Study of Nerve Block Anesthesia for Surgery of Hip Fracture in the Elderly Unknown status NCT02104908 Phase 4
21 Analgesic Effects of the Gastrolith, in Osteoporotic Patients Suffering From Recent Skeletal Pain Caused by Vertebral Fractures Unknown status NCT01482858 Phase 4
22 Does Optimized General Anesthesia Care Reduce Postoperative Delirium? Unknown status NCT02604459 Phase 4 propofol;fentanyl;sevoflurane
23 Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty Unknown status NCT01934049 Phase 4 Total Intravenous Anesthesia and Peripheral nerve blocks
24 Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw Unknown status NCT01219088 Phase 4 Bupivacaine, morphine
25 Monopolar Electrosurgery Versus Ultrasound Scissors in Thoracoscopic Ventral Spondylodesis Unknown status NCT00941213 Phase 4
26 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
27 The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement Unknown status NCT01112436 Phase 4 periarticular injection of multidrug regimen;none of medication preoperatively and intraoperatively
28 Clinical Comparison of Efficacy and Safety of Two Teriparatide Formulations: Osteofortil and Forteo Unknown status NCT01945788 Phase 4 Teriparatide (rDNA origin)
29 The New Skin Stretching Device for Treatment of Limb Tension Wounds Unknown status NCT03141502 Phase 4
30 A One-year Randomized Controlled Trial Evaluating the Impact of Pioglitazone Versus Linagliptin on Bone Turnover Markers Unknown status NCT02429232 Phase 4 Pioglitazone;Linagliptin
31 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole
32 The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion Unknown status NCT01310465 Phase 4 zoledronic acid;sodium chloride
33 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
34 Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus Unknown status NCT02011620 Phase 4
35 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4 etomidate;midazolam;propofol
36 Role of Stress Reduction Protocol on Outcome of Periodontal Therapy Unknown status NCT02487862 Phase 4
37 Bone Turnover in Type 2 Diabetes Patients Unknown status NCT00732121 Phase 4 Sitagliptin;Placebo
38 Manually Versus Digitally Fabricated Removable Partial Dentures Unknown status NCT01191073 Phase 4
39 Efficacy and Safety of Brand Versus Generic Alendronate for Osteoporosis Treatment Unknown status NCT02371252 Phase 4 Generic alendronate
40 Determination of Vitamin D Dose to Maintain Sufficiency Amongst Indian and Malay Women in the Tropics Unknown status NCT02389179 Phase 4 Vitamin D3
41 Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC Unknown status NCT01795794 Phase 4 omeprazole
42 the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle Unknown status NCT02519881 Phase 4
43 Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients Unknown status NCT00912938 Phase 4 zoledronic acid
44 Intranasal Fentanyl for Pain Management Unknown status NCT00882960 Phase 4 intravenous fentanyl;intra-nasal fentanyl
45 Comparison of Efficacy and Safety of Microfracture and Modified Microfracture Unknown status NCT02539030 Phase 4
46 The Hypertension in the Very Elderly Trial (HYVET) Unknown status NCT00122811 Phase 4 Indapamide SR 1.5mg; Perindopril 2-4mg
47 Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss Unknown status NCT02322099 Phase 4 Alendronate;Placebo;Tenofovir disoproxil
48 Study Evaluating InductOs in Diaphyseal Tibia Fractures Completed NCT00161616 Phase 4 InductOs
49 Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants Completed NCT01431560 Phase 4
50 Treatment of Acetabular Posterior Wall Fracture With Anatomical Locking Plate Completed NCT01437150 Phase 4

Search NIH Clinical Center for Bone Fracture

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Bone Fracture cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Bone Fracture:
ALLOB, allogeneic osteoblasts for bone disorders
Bone marrow-derived mesenchymal stem cells for treatment of atrophic nonunion fractures
Map3, multipotent adult progenitor cel-based bone graft for bone injury
Ovation, mesenchymal stem cells for bone repair
PREOB, autologous osteoblasts for bone disorders
Stromal vascular fraction cells for osteoporotic bone fractures
Embryonic/Adult Cultured Cells Related to Bone Fracture:
Bone marrow-derived mesenchymal stem cells PMIDs: 23180104
Bone marrow-derived adherent progenitor cells (MultiStem)
Stromal vascular fraction cells PMIDs: 21605897 16488036
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Genetic Tests for Bone Fracture

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Anatomical Context for Bone Fracture

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MalaCards organs/tissues related to Bone Fracture:

42
Bone, Prostate, Breast, Kidney, Bone Marrow, Testes, Spinal Cord
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Bone Fracture:
# Tissue Anatomical CompartmentCell Relevance
1 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Stromal Cells Potential therapeutic candidate
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Publications for Bone Fracture

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Articles related to Bone Fracture:

(show top 50) (show all 830)
# Title Authors Year
1
Cerebral Edema and Neurological Recovery after Traumatic Brain Injury Are Worsened if Accompanied by a Concomitant Long Bone Fracture. ( 30084745 )
2019
2
Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture. ( 30274548 )
2019
3
Risk factors for ischemic stroke post bone fracture. ( 30414811 )
2019
4
Effects of Sodium-glucose Cotransporter 2 Inhibitors on Amputation, Bone Fracture, and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus Using an Alternative Measure to the Hazard Ratio. ( 30506378 )
2019
5
Role of SMPD3 during Bone Fracture Healing and Regulation of Its Expression. ( 30530524 )
2019
6
Otopathology of Unilateral Cochlear Implantation in Patients With Bilateral Temporal Bone Fracture. ( 30531637 )
2019
7
Vestibular Traumatic Neuroma Following Temporal Bone Fracture. ( 30531646 )
2019
8
Risk of Ischemic Stroke After a Facial Bone Fracture in Elderly Patients. ( 30628941 )
2019
9
Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture Healing. ( 30645111 )
2019
10
Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts. ( 30702934 )
2019
11
Effect of fentanyl nasal packing treatment on patients with acute postoperative pain after closed reduction of nasal bone fracture: a randomized double-blind controlled trial. ( 30734629 )
2019
12
Risk of bone fracture associated with sodium-glucose cotransporter-2 inhibitor treatment: A meta-analysis of randomized controlled trials. ( 30738154 )
2019
13
The effectiveness and safety of cervus and cucumis polypeptide injection in promoting fracture healing after bone fracture surgeries: Protocol for a systematic review and meta-analysis. ( 30762805 )
2019
14
Ultrasound Radiation Force for the Assessment of Bone Fracture Healing in Children: An In Vivo Pilot Study. ( 30813465 )
2019
15
Conservative versus Surgical Therapy in Managing Patients with Facial Nerve Palsy Due to the Temporal Bone Fracture. ( 30815211 )
2019
16
Effect of ultrasound on bone fracture healing: A computational mechanobioregulatory model. ( 30823826 )
2019
17
Perilymphatic fistula and pneumolabyrinth without temporal bone fracture: a rare entity. ( 30826783 )
2019
18
Optimal currents for electrical stimulation of bone fracture repair: A computational analysis including variations in frequency, tissue properties, and fracture morphology. ( 30830978 )
2019
19
Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing. ( 30832329 )
2019
20
The effects of dynamic loading on bone fracture healing under Ilizarov Circular Fixators. ( 30835278 )
2019
21
Finger reduction of nasal bone fracture under local anesthesia: outcomes and patient reported satisfaction. ( 30840815 )
2019
22
The measurement of nose dimensions through the three-dimensional reformation images after nasal bone fracture. ( 30840816 )
2019
23
Bone fracture healing under Ilizarov fixator: influence of fixator configuration, fracture geometry and loading. ( 30869195 )
2019
24
Misplaced incus: an unusual complication of a temporal bone fracture. ( 30898967 )
2019
25
Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture. ( 30944542 )
2019
26
Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling. ( 30948630 )
2019
27
Electrical stimulation-based bone fracture treatment, if it works so well why do not more surgeons use it? ( 30955053 )
2019
28
Early detection of bone metastases of hepatocellular carcinoma reduces bone fracture and paralysis. ( 30957835 )
2019
29
Glucagon-like peptide-1 receptor agonists and risk of bone fracture in patients with type 2 diabetes: A meta-analysis of randomized controlled trials. ( 30974033 )
2019
30
Utilizing Multiple bioMEMS Sensors to Monitor Orthopaedic Strain and Predict Bone Fracture Healing. ( 31042313 )
2019
31
Are postoperative prophylactic antibiotics in closed reduction of nasal bone fracture valuable?: prospective study of 30 cases. ( 31048645 )
2019
32
Influence of Skull Base or Frontal Bone Fracture on the Result of Treatment for Le Fort Type Maxillofacial Fractures: Outcomes of Le Fort IV Fractures. ( 31057291 )
2019
33
Peripheral Vestibular Organ Degeneration After Temporal Bone Fracture: A Human Otopathology Study. ( 31074866 )
2019
34
Low Hemoglobin Is Associated With Low Bone Mineral Density and High Risk of Bone Fracture in Male Adults: A Retrospective Medical Record Review Study. ( 31081448 )
2019
35
Novel, cost-effective, Cu-doped calcium silicate nanoparticles for bone fracture intervention: Inherent bioactivity and in vivo performance. ( 29656599 )
2019
36
Application of mesenchymal stem cells to enhance non-union bone fracture healing. ( 29673055 )
2019
37
Optimal administration frequency and dose of teriparatide for acceleration of biomechanical healing of long-bone fracture in a mouse model. ( 29721806 )
2019
38
Application of resampling techniques to improve the quality of survival analysis risk curves for human frontal bone fracture. ( 29753560 )
2019
39
Can quantitative computed tomography detect bone morphological changes associated with catastrophic proximal sesamoid bone fracture in Thoroughbred racehorses? ( 29758110 )
2019
40
Accuracy in Screw Selection in a Cadaveric, Small-Bone Fracture Model. ( 29801935 )
2018
41
Effects of obesity on the healing of bone fracture in mice. ( 29880016 )
2018
42
Otopathologic Changes in the Cochlea following Head Injury without Temporal Bone Fracture. ( 29890895 )
2018
43
Pronounced femur malunion after pathological bone fracture due to a simple bone cyst in the shaft of the femur, treated using Ilizarov fixation: a case report. ( 29925426 )
2018
44
Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover. ( 29931664 )
2018
45
Discovery of a novel 2-(1H-pyrazolo[3,4-b]pyridin-1-yl)thiazole derivative as an EP1 receptor antagonist and in vivo studies in a bone fracture model. ( 29934246 )
2018
46
Dietary fat, saturated fatty acid, and monounsaturated fatty acid intakes and risk of bone fracture: a systematic review and meta-analysis of observational studies. ( 29947872 )
2018
47
New Insights in Understanding and Treating Bone Fracture Pain. ( 29948820 )
2018
48
Effect of ultrasound on bone fracture healing: A computational bioregulatory model. ( 29975857 )
2018
49
Role of Dynamic Loading on Early Stage of Bone Fracture Healing. ( 29987542 )
2018
50
A Model-Based Approach to Investigate the Effect of a Long Bone Fracture on Ultrasound Strain Elastography. ( 29994472 )
2018
Sources

Variations for Bone Fracture

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Expression for Bone Fracture

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Search GEO for disease gene expression data for Bone Fracture.
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Pathways for Bone Fracture

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Pathways related to Bone Fracture according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Adipogenesis 1
11.62 BMP2 STAT3
2
Th1 Differentiation Pathway 66
Show member pathways
 11.59 STAT3 TLR4
3
MAPK Pathway 73
Show member pathways
 11.55 STAT3 TLR4
4
Visual Cycle in Retinal Rods 65
11.38 CRP STAT3
5
HIF-1 signaling pathway 38
11.37 STAT3 TLR4
6
Cytokine production by Th17 cells in CF (Mouse model) 23
Show member pathways
 11.29 STAT3 TLR4
7
Notch-mediated HES/HEY network 1
10.94 BGLAP STAT3
8
Interleukin-11 Signaling Pathway 1
10.8 BGLAP STAT3
9
Development_Thrombopoetin signaling via JAK-STAT pathway 23
10.79 CRP STAT3
10
IL-10 Pathway 65
10.5 STAT3 TLR4
11
Development_Leptin signaling via JAK/STAT and MAPK cascades 23
Show member pathways
 10.1 CRP STAT3
Sources

GO Terms for Bone Fracture

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Biological processes related to Bone Fracture according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 response to organic cyclic compound GO:0014070 9.52 BGLAP STAT3
2 activation of MAPK activity GO:0000187 9.51 BMP2 TLR4
3 response to ethanol GO:0045471 9.49 BGLAP STAT3
4 response to bacterium GO:0009617 9.48 BMP2 TLR4
5 osteoblast differentiation GO:0001649 9.46 BGLAP BMP2
6 ossification GO:0001503 9.43 BGLAP BMP2
7 cellular response to organic cyclic compound GO:0071407 9.4 BMP2 STAT3
8 cellular response to growth factor stimulus GO:0071363 9.37 BGLAP BMP2
9 bone mineralization GO:0030282 9.32 BGLAP BMP2
10 acute-phase response GO:0006953 9.26 CRP STAT3
11 positive regulation of gene expression GO:0010628 9.26 BMP2 CRP STAT3 TLR4
12 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 BMP2 STAT3
13 inflammatory response GO:0006954 8.92 BMP2 CRP STAT3 TLR4
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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
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47 MGI
50 NCI
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52 NDF-RT
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63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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