BMND17
MCID: BNM031
MIFTS: 16

Bone Mineral Density Quantitative Trait Locus 17 (BMND17)

Categories: Bone diseases, Fetal diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Bone Mineral Density Quantitative Trait Locus 17

MalaCards integrated aliases for Bone Mineral Density Quantitative Trait Locus 17:

Name: Bone Mineral Density Quantitative Trait Locus 17 58 6 41
Bone Mineral Density, Low, Susceptibility to 58
Bone Mineral Density, Low 58
Bmnd17 58

Classifications:



External Ids:

OMIM 58 615311

Summaries for Bone Mineral Density Quantitative Trait Locus 17

MalaCards based summary : Bone Mineral Density Quantitative Trait Locus 17, also known as bone mineral density, low, susceptibility to, is related to bone mineral density quantitative trait locus 3. An important gene associated with Bone Mineral Density Quantitative Trait Locus 17 is LGR4 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 4). The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include bone.

Description from OMIM: 615311

Related Diseases for Bone Mineral Density Quantitative Trait Locus 17

Symptoms & Phenotypes for Bone Mineral Density Quantitative Trait Locus 17

Clinical features from OMIM:

615311

Drugs & Therapeutics for Bone Mineral Density Quantitative Trait Locus 17

Drugs for Bone Mineral Density Quantitative Trait Locus 17 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved Not Applicable 1401-55-4
2
Benzocaine Approved, Investigational Not Applicable 1994-09-7, 94-09-7 2337
3
Vitamin D3 Approved, Nutraceutical Not Applicable 67-97-0 5280795 6221
4
Ergocalciferol Approved, Nutraceutical Not Applicable 50-14-6 5280793
5
Calcium Approved, Nutraceutical Not Applicable 7440-70-2 271
6
Vitamin D Approved, Nutraceutical, Vet_approved Not Applicable 1406-16-2
7 Calciferol Not Applicable
8 Vitamins Not Applicable
9 Bone Density Conservation Agents Not Applicable
10 Hormones Not Applicable
11 Calcium Supplement Not Applicable
12 Trace Elements Not Applicable
13 Nutrients Not Applicable
14 Calcium, Dietary Not Applicable
15 Ergocalciferols Not Applicable
16 Micronutrients Not Applicable
17 Vitamin D2 Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Assessment of Bone Mineral Density During Pregnancy Completed NCT02480023 Phase 1
2 Effects of Whole Body Vibration and Pilates on Bone Mineral Density in Postmenopausal Women Completed NCT02769143 Not Applicable
3 High-dose Vitamin D Supplementation for ADT-induced Side Effects Completed NCT02064946 Not Applicable
4 The Health of Competitive Fitness Athletes Completed NCT03007459

Search NIH Clinical Center for Bone Mineral Density Quantitative Trait Locus 17

Genetic Tests for Bone Mineral Density Quantitative Trait Locus 17

Anatomical Context for Bone Mineral Density Quantitative Trait Locus 17

MalaCards organs/tissues related to Bone Mineral Density Quantitative Trait Locus 17:

42
Bone

Publications for Bone Mineral Density Quantitative Trait Locus 17

Articles related to Bone Mineral Density Quantitative Trait Locus 17:

# Title Authors Year
1
Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits. ( 23644456 )
2013

Variations for Bone Mineral Density Quantitative Trait Locus 17

ClinVar genetic disease variations for Bone Mineral Density Quantitative Trait Locus 17:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 LGR4 NM_018490.3(LGR4): c.376C> T (p.Arg126Ter) single nucleotide variant association rs587777005 GRCh37 Chromosome 11, 27412666: 27412666
2 LGR4 NM_018490.3(LGR4): c.376C> T (p.Arg126Ter) single nucleotide variant association rs587777005 GRCh38 Chromosome 11, 27391119: 27391119

Expression for Bone Mineral Density Quantitative Trait Locus 17

Search GEO for disease gene expression data for Bone Mineral Density Quantitative Trait Locus 17.

Pathways for Bone Mineral Density Quantitative Trait Locus 17

GO Terms for Bone Mineral Density Quantitative Trait Locus 17

Sources for Bone Mineral Density Quantitative Trait Locus 17

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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