Borst-Jadassohn Intraepidermal Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards integrated aliases for Borst-Jadassohn Intraepidermal Carcinoma:

Name: Borst-Jadassohn Intraepidermal Carcinoma ¹² ¹⁵

Intraepidermal Epithelioma of Jadassohn ¹² ⁷⁰

Bowen's Disease, Clonal ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7039

SNOMED-CT ⁶⁷ 403886007

UMLS ⁷⁰ C0334260 C2937231

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Summaries for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards based summary : Borst-Jadassohn Intraepidermal Carcinoma, also known as intraepidermal epithelioma of jadassohn, is related to cervical basaloid squamous cell carcinoma and gastric signet ring cell adenocarcinoma. An important gene associated with Borst-Jadassohn Intraepidermal Carcinoma is KRT7 (Keratin 7), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Affiliated tissues include breast, lung and skin, and related phenotypes are digestive/alimentary and integument

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Related Diseases for Borst-Jadassohn Intraepidermal Carcinoma

Diseases related to Borst-Jadassohn Intraepidermal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 451)

#	Related Disease	Score	Top Affiliating Genes
1	cervical basaloid squamous cell carcinoma	10.5	KRT7 CDKN2A
2	gastric signet ring cell adenocarcinoma	10.5	PIP KRT7
3	leukoplakia of penis	10.5	KRT7 CEACAM5
4	male urethral cancer	10.5	KRT5 CDKN2A
5	ureter squamous cell carcinoma	10.4	KRT7 KRT5
6	bartholin's gland disease	10.4	PIP KRT7
7	bartholin's gland carcinoma	10.4	PIP KRT7
8	mucinous adenofibroma	10.4	KRT7 CEACAM5
9	cervical adenoid cystic carcinoma	10.4	KRT7 CDKN2A
10	breast hemangioma	10.4	TP53 KRT7
11	vulvar intraepithelial neoplasia	10.4	TP53 CDKN2A
12	parotid gland adenoid cystic carcinoma	10.4	CEACAM5 CDKN2A
13	esophagus verrucous carcinoma	10.4	TP53 CDKN2A
14	melanoacanthoma	10.4	MLANA KRT7
15	penile urethral cancer	10.4	KRT5 CDKN2A
16	subareolar duct papillomatosis	10.4	KRT7 KRT5
17	fox-fordyce disease	10.4	PIP CEACAM5
18	adult teratoma	10.4	TP53 CEACAM5
19	nipple benign neoplasm	10.4	KRT7 KRT5
20	renal pelvis adenocarcinoma	10.4	KRT7 CEACAM5
21	basaloid lung carcinoma	10.4	TP53 KRT5
22	auditory system benign neoplasm	10.4	KRT7 KRT5
23	bile duct cystadenocarcinoma	10.4	KRT7 CEACAM5
24	human papillomavirus infectious disease	10.4	TP53 CDKN2A
25	microinvasive cervical squamous cell carcinoma	10.4	KRT7 KRT5
26	sarcomatoid transitional cell carcinoma	10.4	TP53 MLANA
27	nipples, supernumerary	10.4	PIP KRT20
28	bladder benign neoplasm	10.4	KRT7 KRT20
29	spitz nevus	10.4	TP53 CDKN2A
30	nephrogenic adenoma of urinary bladder	10.4	KRT7 KRT20
31	cervical serous adenocarcinoma	10.4	MLANA CEACAM5
32	breast squamous cell carcinoma	10.4	TP53 KRT5
33	adenoid basal cell carcinoma	10.4	KRT7 CEACAM5
34	breast cystic hypersecretory carcinoma	10.4	KRT5 CEACAM5
35	lung acinar adenocarcinoma	10.4	PIP KRT20
36	appendiceal neoplasm	10.4	KRT7 CEACAM5
37	maxillary sinus benign neoplasm	10.4	CEACAM5 CDKN2A
38	gallbladder squamous cell carcinoma	10.4	KRT5 CEACAM5
39	cystitis cystica	10.4	KRT7 KRT20
40	breast adenomyoepithelioma	10.4	KRT5 KRT14
41	lung clear cell carcinoma	10.4	KRT7 KRT5
42	laryngeal small cell carcinoma	10.4	KRT5 CDKN2A
43	barre-lieou syndrome	10.4	PIP MLANA
44	biliary papillomatosis	10.4	KRT7 CEACAM5
45	clear cell acanthoma	10.4	KRT10 IVL
46	trachea carcinoma in situ	10.4	KRT14 CDKN2A
47	urinary bladder small cell neuroendocrine carcinoma	10.4	KRT7 KRT20
48	gallbladder adenoma	10.4	KRT7 CDKN2A
49	ovarian seromucinous carcinoma	10.4	TP53 KRT7 CDKN2A
50	jejunal cancer	10.4	KRT7 KRT20

Graphical network of the top 20 diseases related to Borst-Jadassohn Intraepidermal Carcinoma:

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Symptoms & Phenotypes for Borst-Jadassohn Intraepidermal Carcinoma

MGI Mouse Phenotypes related to Borst-Jadassohn Intraepidermal Carcinoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.56	CD4 CDKN2A KRT14 KRT16 KRT17 KRT5
2	integument	MP:0010771	9.36	CD4 CD8A CDKN2A FECH KRT14 KRT16

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Drugs & Therapeutics for Borst-Jadassohn Intraepidermal Carcinoma

Search Clinical Trials , NIH Clinical Center for Borst-Jadassohn Intraepidermal Carcinoma

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Genetic Tests for Borst-Jadassohn Intraepidermal Carcinoma

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Anatomical Context for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards organs/tissues related to Borst-Jadassohn Intraepidermal Carcinoma:

⁴⁰

Breast, Lung, Skin, Thymus, Uterus, Appendix, Colon

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Publications for Borst-Jadassohn Intraepidermal Carcinoma

Articles related to Borst-Jadassohn Intraepidermal Carcinoma:

#	Title	Authors	PMID	Year
1	[Groups at high risk for skin cancer]. ⁶¹	Kurdina MI...Vinogradova NN	7785248	1994
2	Intraepidermal epithelioma of Jadassohn. ⁶¹	Sampson DD...Indianer L	3709225	1986
3	Intraepidermal epithelioma of Jadassohn. ⁶¹	Holubar K	7437312	1980
4	Proceedings: Intraepidermal epithelioma of Jadassohn. ⁶¹	Siegel JM	4281292	1974

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Genes for Borst-Jadassohn Intraepidermal Carcinoma

Genes related to Borst-Jadassohn Intraepidermal Carcinoma (0 elite genes):

(show all 21)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KRT7	Keratin 7	Protein Coding	6.76	DISEASES inferred ¹⁵
2	TP53	Tumor Protein P53	Protein Coding	6.76	DISEASES inferred ¹⁵
3	PIP	Prolactin Induced Protein	Protein Coding	6.52	DISEASES inferred ¹⁵
4	KRT10	Keratin 10	Protein Coding	6.48	DISEASES inferred ¹⁵
5	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	6.21	DISEASES inferred ¹⁵
6	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	6.09	DISEASES inferred ¹⁵
7	MLANA	Melan-A	Protein Coding	6.07	DISEASES inferred ¹⁵
8	KRT5	Keratin 5	Protein Coding	5.86	DISEASES inferred ¹⁵
9	IVL	Involucrin	Protein Coding	5.72	DISEASES inferred ¹⁵
10	KRT20	Keratin 20	Protein Coding	5.67	DISEASES inferred ¹⁵
11	TLR7	Toll Like Receptor 7	Protein Coding	5.43	DISEASES inferred ¹⁵
12	KRT14	Keratin 14	Protein Coding	5.41	DISEASES inferred ¹⁵
13	FECH	Ferrochelatase	Protein Coding	5.4	DISEASES inferred ¹⁵
14	CD8A	CD8a Molecule	Protein Coding	5.38	DISEASES inferred ¹⁵
15	CD4	CD4 Molecule	Protein Coding	5.37	DISEASES inferred ¹⁵
16	KRT17	Keratin 17	Protein Coding	5.37	DISEASES inferred ¹⁵
17	C2orf81	Chromosome 2 Open Reading Frame 81	Protein Coding	5.37	DISEASES inferred ¹⁵
18	AS3MT	Arsenite Methyltransferase	Protein Coding	5.3	DISEASES inferred ¹⁵
19	PTGER4	Prostaglandin E Receptor 4	Protein Coding	5.2	DISEASES inferred ¹⁵
20	KRT16	Keratin 16	Protein Coding	5.17	DISEASES inferred ¹⁵
21	CDH1	Cadherin 1	Protein Coding	5.16	DISEASES inferred ¹⁵

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Variations for Borst-Jadassohn Intraepidermal Carcinoma

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Expression for Borst-Jadassohn Intraepidermal Carcinoma

Search GEO for disease gene expression data for Borst-Jadassohn Intraepidermal Carcinoma.

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Pathways for Borst-Jadassohn Intraepidermal Carcinoma

Pathways related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Developmental Biology ⁶⁵ Show member pathways Axon guidance ⁶⁵	13.22	KRT7 KRT5 KRT20 KRT17 KRT16 KRT14
2	Cytoskeletal Signaling ⁴	12.25	KRT7 KRT5 KRT20 KRT17 KRT10
3	Estrogen signaling pathway (KEGG) ³⁶	11.79	KRT20 KRT17 KRT16 KRT14 KRT10
4	Keratinization ⁶⁵ Show member pathways Formation of the cornified envelope ⁶⁵	11.68	KRT7 KRT5 KRT20 KRT17 KRT16 KRT14
5	Cytoskeleton remodeling Neurofilaments ²³ Show member pathways Cytoskeleton remodeling Keratin filaments ²³	11.59	KRT7 KRT5 KRT17 KRT16 KRT14
6	Glucocorticoid receptor regulatory network ¹	11.54	TP53 KRT5 KRT17 KRT14
7	Dendritic Cells Developmental Lineage Pathway ⁶⁴	11.48	TLR7 CD8A CD4
8	Staphylococcus aureus infection ³⁶	11.34	KRT20 KRT17 KRT16 KRT14 KRT10

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GO Terms for Borst-Jadassohn Intraepidermal Carcinoma

Cellular components related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	intermediate filament	GO:0005882	9.17	KRT7 KRT5 KRT20 KRT17 KRT16 KRT14

Biological processes related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	keratinization	GO:0031424	9.56	KRT7 KRT5 KRT20 KRT17 KRT16 KRT14
2	keratinocyte differentiation	GO:0030216	9.33	KRT16 KRT10 IVL
3	hemidesmosome assembly	GO:0031581	9.26	KRT5 KRT14
4	cornification	GO:0070268	9.23	KRT7 KRT5 KRT20 KRT17 KRT16 KRT14

Molecular functions related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	structural constituent of cytoskeleton	GO:0005200	9.26	KRT5 KRT20 KRT16 KRT14
2	MDM2/MDM4 family protein binding	GO:0097371	9.16	TP53 CDKN2A
3	structural molecule activity	GO:0005198	9.02	KRT20 KRT17 KRT16 KRT14 KRT10

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