Borst-Jadassohn Intraepidermal Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards integrated aliases for Borst-Jadassohn Intraepidermal Carcinoma:

Name: Borst-Jadassohn Intraepidermal Carcinoma ¹² ¹⁵

Intraepidermal Epithelioma of Jadassohn ¹² ⁷⁴

Bowen's Disease, Clonal ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7039

UMLS ⁷⁴ C0334260 C2937231

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Summaries for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards based summary : Borst-Jadassohn Intraepidermal Carcinoma, also known as intraepidermal epithelioma of jadassohn, is related to mucinous tubular and spindle renal cell carcinoma and appendix cancer. An important gene associated with Borst-Jadassohn Intraepidermal Carcinoma is KRT10 (Keratin 10), and among its related pathways/superpathways are Pathways in cancer and Keratinization. Affiliated tissues include breast, tongue and cervix, and related phenotypes are digestive/alimentary and integument

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Related Diseases for Borst-Jadassohn Intraepidermal Carcinoma

Diseases related to Borst-Jadassohn Intraepidermal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 191)

#	Related Disease	Score	Top Affiliating Genes
1	mucinous tubular and spindle renal cell carcinoma	10.5	KRT10 KRT7
2	appendix cancer	10.4	KRT7 TP53
3	mixed cell type cancer	10.4	KRT7 TP53
4	cystic teratoma	10.4	KRT7 TP53
5	acinar cell carcinoma	10.4	KRT7 TP53
6	pseudomyxoma peritonei	10.4	KRT7 TP53
7	epithelial-myoepithelial carcinoma	10.4	KRT7 TP53
8	biliary papillomatosis	10.4	KRT7 TP53
9	pleomorphic carcinoma	10.4	KRT7 TP53
10	granulosa cell tumor of the ovary	10.4	KRT7 TP53
11	suppressor of tumorigenicity 3	10.4	CDKN2A TP53
12	spiradenoma	10.4	KRT7 TP53
13	cervix small cell carcinoma	10.4	CDKN2A TP53
14	meningeal melanomatosis	10.4	CDKN2A TP53
15	dedifferentiated liposarcoma	10.4	CDKN2A TP53
16	mucinous bronchioloalveolar adenocarcinoma	10.4	CDKN2A KRT7
17	adenocarcinoma in situ	10.4	CDKN2A KRT7
18	cervical adenosquamous carcinoma	10.4	CDKN2A KRT7
19	well-differentiated liposarcoma	10.4	CDKN2A KRT7
20	acanthoma	10.4	KRT10 KRT17
21	epidermolysis bullosa simplex, dowling-meara type	10.4	KRT10 KRT5
22	ampulla of vater adenocarcinoma	10.4	KRT17 KRT7
23	ovarian mucinous neoplasm	10.4	KRT17 KRT7
24	breast benign neoplasm	10.4	KRT5 TP53
25	thoracic benign neoplasm	10.4	KRT5 TP53
26	sweat gland disease	10.4	KRT5 KRT7
27	peritoneum cancer	10.4	KRT5 KRT7
28	atypical choroid plexus papilloma	10.4	KRT5 KRT7
29	breast secretory carcinoma	10.4	KRT5 KRT7
30	lipoadenoma	10.4	KRT5 KRT7
31	cystadenofibroma	10.4	KRT5 KRT7
32	pleural cancer	10.4	CDKN2A KRT5
33	bladder squamous cell carcinoma	10.4	CDKN2A TP53
34	nodular hidradenoma	10.4	KRT10 KRT7
35	clear cell basal cell carcinoma	10.3	KRT17 KRT7
36	basal cell carcinoma, infundibulocystic	10.3	KRT10 KRT17
37	spitz nevus	10.3	CDKN2A TP53
38	balloon cell malignant melanoma	10.3	KRT5 KRT7
39	benign breast adenomyoepithelioma	10.3	KRT5 KRT7
40	ceruminoma	10.3	KRT5 KRT7
41	eccrine acrospiroma	10.3	KRT10 KRT17
42	adenoid basal cell carcinoma	10.3	CDKN2A KRT7
43	bile duct adenoma	10.3	CDKN2A KRT7
44	benign mesothelioma	10.3	KRT5 KRT7
45	endocervical carcinoma	10.3	CDKN2A KRT7
46	scrotal carcinoma	10.3	CDKN2A TP53
47	sensory organ benign neoplasm	10.3	KRT5 KRT7
48	cerebral convexity meningioma	10.3	CDH1 TP53
49	bile duct mucoepidermoid carcinoma	10.3	KRT5 KRT7
50	nasal cavity cancer	10.3	CDKN2A KRT7

Graphical network of the top 20 diseases related to Borst-Jadassohn Intraepidermal Carcinoma:

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Symptoms & Phenotypes for Borst-Jadassohn Intraepidermal Carcinoma

MGI Mouse Phenotypes related to Borst-Jadassohn Intraepidermal Carcinoma:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.8	CDH1 CDKN2A KRT17 KRT5 MMP21 PTCH1
2	integument	MP:0010771	9.7	CDH1 CDKN2A KRT17 KRT5 OVOL1 PTCH1
3	no phenotypic analysis	MP:0003012	9.43	CDH1 CDKN2A KRT17 KRT5 PTCH1 TP53
4	pigmentation	MP:0001186	8.92	CDKN2A KRT17 PTCH1 TP53

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Drugs & Therapeutics for Borst-Jadassohn Intraepidermal Carcinoma

Search Clinical Trials , NIH Clinical Center for Borst-Jadassohn Intraepidermal Carcinoma

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Genetic Tests for Borst-Jadassohn Intraepidermal Carcinoma

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Anatomical Context for Borst-Jadassohn Intraepidermal Carcinoma

MalaCards organs/tissues related to Borst-Jadassohn Intraepidermal Carcinoma:

⁴²

Breast, Tongue, Cervix, Lung, Skin, Ovary, Bone

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Publications for Borst-Jadassohn Intraepidermal Carcinoma

Articles related to Borst-Jadassohn Intraepidermal Carcinoma:

#	Title	Authors	Year
1	Intraepidermal epithelioma of Jadassohn. ( 3709225 )	Sampson DD...Indianer L	1986
2	Intraepidermal epithelioma of Jadassohn. ( 7437312 )	Holubar K	1980
3	Proceedings: Intraepidermal epithelioma of Jadassohn. ( 4281292 )	Siegel JM	1974

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Genes for Borst-Jadassohn Intraepidermal Carcinoma

Genes related to Borst-Jadassohn Intraepidermal Carcinoma (0 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KRT10	Keratin 10	Protein Coding	16.12	DISEASES inferred ¹⁵
2	TP53	Tumor Protein P53	Protein Coding	16.04	DISEASES inferred ¹⁵
3	KRT7	Keratin 7	Protein Coding	15.58	DISEASES inferred ¹⁵
4	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	15.47	DISEASES inferred ¹⁵
5	CNTROB	Centrobin, Centriole Duplication And Spindle Assembly Protein	Protein Coding	15.02	DISEASES inferred ¹⁵
6	KRT17	Keratin 17	Protein Coding	14.82	DISEASES inferred ¹⁵
7	KRT5	Keratin 5	Protein Coding	14.78	DISEASES inferred ¹⁵
8	CDH1	Cadherin 1	Protein Coding	14.48	DISEASES inferred ¹⁵
9	MMP21	Matrix Metallopeptidase 21	Protein Coding	14.47	DISEASES inferred ¹⁵
10	PTCH1	Patched 1	Protein Coding	14.39	DISEASES inferred ¹⁵
11	LINC01191	Long Intergenic Non-Protein Coding RNA 1191	RNA Gene	5.4	DISEASES inferred ¹⁵
12	OVOL1	Ovo Like Transcriptional Repressor 1	Protein Coding	5.27	DISEASES inferred ¹⁵

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Variations for Borst-Jadassohn Intraepidermal Carcinoma

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Expression for Borst-Jadassohn Intraepidermal Carcinoma

Search GEO for disease gene expression data for Borst-Jadassohn Intraepidermal Carcinoma.

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Pathways for Borst-Jadassohn Intraepidermal Carcinoma

Pathways related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Pathways in cancer ³⁸	12.46	CDH1 CDKN2A PTCH1 TP53
2	Keratinization ⁶⁷ Show member pathways Formation of the cornified envelope ⁶⁷	11.91	KRT10 KRT17 KRT5 KRT7
3	Cytoskeleton remodeling Neurofilaments ²³ Show member pathways Cytoskeleton remodeling Keratin filaments ²³	11.53	KRT17 KRT5 KRT7
4	Cytoskeletal Signaling ⁴	11.51	CDH1 KRT10 KRT17 KRT5 KRT7
5	Glucocorticoid receptor regulatory network ¹	11.35	KRT17 KRT5 TP53
6	Bladder cancer ¹ ³⁸	11	CDH1 CDKN2A TP53
7	Oncogene Induced Senescence ⁶⁷	10.96	CDKN2A TP53
8	Inhibition of Ribosome Biogenesis by p14(ARF) ⁶⁵	10.75	CDKN2A TP53
9	TP53 Network ¹ Show member pathways Activation, translocation and oligomerization of BAX ⁶⁷	10.71	CDKN2A TP53

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GO Terms for Borst-Jadassohn Intraepidermal Carcinoma

Cellular components related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	intermediate filament	GO:0005882	8.92	KRT10 KRT17 KRT5 KRT7

Biological processes related to Borst-Jadassohn Intraepidermal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of transcription, DNA-templated	GO:0045892	9.62	CDKN2A OVOL1 PTCH1 TP53
2	keratinization	GO:0031424	9.46	KRT10 KRT17 KRT5 KRT7
3	replicative senescence	GO:0090399	9.26	CDKN2A TP53
4	cornification	GO:0070268	9.26	KRT10 KRT17 KRT5 KRT7
5	epidermis development	GO:0008544	8.92	KRT17 KRT5 OVOL1 PTCH1

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