MCID: BWN003
MIFTS: 42

Bowenoid Papulosis

Categories: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

MalaCards integrated aliases for Bowenoid Papulosis:

Name: Bowenoid Papulosis 54 74
Bp 54

Classifications:



External Ids:

UMLS 74 C0334106

Summaries for Bowenoid Papulosis

MalaCards based summary : Bowenoid Papulosis, also known as bp, is related to squamous cell carcinoma and cervical intraepithelial neoplasia. An important gene associated with Bowenoid Papulosis is CCND1 (Cyclin D1), and among its related pathways/superpathways are Human cytomegalovirus infection and PI3K-Akt signaling pathway. Affiliated tissues include breast, kidney and heart, and related phenotypes are Reduced mammosphere formation and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 77 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

Related Diseases for Bowenoid Papulosis

Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 385)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 30.8 CCND1 CDKN2A PTGS2
2 cervical intraepithelial neoplasia 30.3 CDKN2A TERT
3 papilloma 30.1 CCND1 CDKN2A FLG
4 nasopharyngeal carcinoma 29.7 CCND1 CDKN2A TERT
5 oral cancer 29.2 CCND1 CDKN2A PTGS2
6 gastric cancer 29.1 CCND1 CDKN2A PTGS2 TERT
7 hepatocellular carcinoma 28.6 CCND1 CDKN2A PTGS2 TERT
8 lung cancer 27.9 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
9 interstitial cystitis 12.0
10 bartsocas-papas syndrome 11.7
11 knuckle pads, leukonychia, and sensorineural deafness 11.1
12 growth hormone insensitivity with immunodeficiency 11.1
13 d-bifunctional protein deficiency 11.1
14 leukemia, chronic myeloid 11.1
15 vertebrobasilar insufficiency 11.1
16 bowen's disease 10.7
17 bullous pemphigoid 10.3
18 acquired immunodeficiency syndrome 10.3
19 in situ carcinoma 10.3
20 thalassemia 10.3
21 clear cell adenocarcinoma of the ovary 10.3 CCND1 CCNE1
22 cystitis 10.3
23 breast papillomatosis 10.2 CCND1 CDKN2A
24 tonsil squamous cell carcinoma 10.2 CCND1 CDKN2A
25 endometrial squamous cell carcinoma 10.2 CCND1 CDKN2A
26 oral leukoplakia 10.2 CCND1 CDKN2A
27 ischemic fasciitis 10.2 CCND1 CDKN2A
28 verrucous carcinoma 10.2 CCND1 CDKN2A
29 pre-malignant neoplasm 10.2 CCND1 CDKN2A
30 chondromyxoid fibroma 10.2 CCND1 CDKN2A
31 laryngeal disease 10.2 CCND1 CDKN2A
32 oropharynx cancer 10.2 CCND1 CDKN2A
33 pharynx cancer 10.2 CCND1 CDKN2A
34 hypertension, essential 10.2
35 inverted papilloma 10.2 CCND1 CDKN2A
36 penile cancer 10.2 CCND1 CDKN2A
37 nasopharyngeal disease 10.2 CCND1 CDKN2A
38 retinal cancer 10.2 CCND1 CDKN2A
39 breast cancer 10.2
40 purulent endophthalmitis 10.1 CCNE1 TERT
41 cervix disease 10.1 CCND1 CDKN2A
42 systemic lupus erythematosus 10.1
43 suppressor of tumorigenicity 3 10.1
44 dermatitis, atopic 10.1
45 leukemia 10.1
46 squamous cell papilloma 10.1
47 skin epithelioid hemangioma 10.1
48 dermatitis 10.1
49 hairy cell leukemia 10.1
50 histiocytoid hemangioma 10.1

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to Bowenoid Papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

GenomeRNAi Phenotypes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.26 CCND1 CCNE1 PPARG PTGS2
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.17 CCNE1 CDKN2A TERT
3 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.17 CCND1 CCNE1 CDKN2A TERT

MGI Mouse Phenotypes related to Bowenoid Papulosis:

47 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.99 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
2 endocrine/exocrine gland MP:0005379 9.95 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
3 growth/size/body region MP:0005378 9.93 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
4 hematopoietic system MP:0005397 9.91 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
5 digestive/alimentary MP:0005381 9.89 CCND1 CCNE1 CDKN2A PTGS2 TERT
6 immune system MP:0005387 9.88 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
7 neoplasm MP:0002006 9.8 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
8 integument MP:0010771 9.77 CCND1 CCNE1 CDKN2A PPARG PTGS2
9 nervous system MP:0003631 9.73 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
10 normal MP:0002873 9.55 CCND1 CCNE1 PPARG PTGS2 TERT
11 reproductive system MP:0005389 9.43 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
12 skeleton MP:0005390 9.1 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT

Drugs & Therapeutics for Bowenoid Papulosis

Search Clinical Trials , NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

MalaCards organs/tissues related to Bowenoid Papulosis:

42
Breast, Kidney, Heart, Skin, Brain, Endothelial, Liver

Publications for Bowenoid Papulosis

Articles related to Bowenoid Papulosis:

(show top 50) (show all 2965)
# Title Authors Year
1
Identification and Mapping of a 2,009-bp DNA Deletion in SERPING1 of a Hereditary Angioedema Patient. ( 30923640 )
2019
2
Epidermal mast cells in Bowenoid papulosis during topical imiquimod therapy. ( 30204264 )
2019
3
Bowenoid papulosis unveiling a rare cause of immunosuppression. ( 30999833 )
2019
4
Brucellosis in an adult female from Fate Bell Rock Shelter, Lower Pecos, Texas (4000-1300 BP). ( 30710889 )
2019
5
Genetic Polymorphism of HLA-G 14-bp Insertion/Deletion in Pancreas Transplant Recipients and Its Association With Type 1 Diabetes Mellitus. ( 30702046 )
2019
6
Association of 32-bp deletion polymorphism and promoter methylation of PTEN and hepatitis C virus induced hepatocellular carcinoma. ( 31109254 )
2019
7
circRNA of AR-suppressed PABPC1 91 bp enhances the cytotoxicity of natural killer cells against hepatocellular carcinoma via upregulating UL16 binding protein 1. ( 30655779 )
2019
8
Intensive BP control and incident kidney disease: what can we learn from urinary biomarkers? ( 30898341 )
2019
9
Association of eNOS 27-bp VNTR, 894G>T and 786T>C polymorphisms with susceptibility to Legg-Calve-Perthes Disease in Iranian children. ( 30890857 )
2019
10
Erratum: Novel 4-bp Intronic Deletion (c.1560+3_1560+6del) in LEMD3 in a Korean Patient With Osteopoikilosis. ( 30430792 )
2019
11
Genome Sequence of Bordetella pertussis Vaccine Strain BP 165. ( 31000545 )
2019
12
VEGF Promoter Region 18-bp Insertion-Deletion Polymorphism in Sickle Cell Disease Patients with Microalbuminuria: A Pilot Study. ( 30988564 )
2019
13
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea. ( 29951886 )
2019
14
Prospective external validation of the Predicting Out-of-OFfice Blood Pressure (PROOF-BP) strategy for triaging ambulatory monitoring in the diagnosis and management of hypertension: observational cohort study. ( 30948382 )
2019
15
Diagnostic Effect of the Single BP Cut-Offs for Identifying Elevated BP and Hypertension in Adolescents Aged 13-17 Years. ( 30707250 )
2019
16
Improving Blood Pressure Among African Americans With Hypertension Using a Mobile Health Approach (the MI-BP App): Protocol for a Randomized Controlled Trial. ( 30681965 )
2019
17
Blood pressure checks and diagnosing hypertension (BP-CHECK): Design and methods of a randomized controlled diagnostic study comparing clinic, home, kiosk, and 24-hour ambulatory BP monitoring. ( 30634036 )
2019
18
Dopamine-beta-hydroxylase 19-bp insertion/deletion polymorphism affects medication overuse in patients with chronic migraine. ( 30972508 )
2019
19
Breaking up sitting time after stroke - How much less sitting is needed to improve blood pressure after stroke (BUST-BP-Dose): Protocol for a dose-finding study. ( 30740549 )
2019
20
A 4-bp deletion promoter variant (rs984225803) is associated with mild OCA4 among Japanese patients. ( 30019506 )
2019
21
Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use. ( 30936032 )
2019
22
Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. ( 30190611 )
2019
23
Peridialysis BP levels and risk of all-cause mortality: a dose-response meta-analysis. ( 30209306 )
2019
24
Correction: Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. ( 30275510 )
2019
25
In response to letter: OSA and BP: Too good to be true? ( 30284260 )
2019
26
Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos. ( 30300651 )
2019
27
Effects of DRD2 splicing-regulatory polymorphism and DRD4 48 bp VNTR on crack cocaine addiction. ( 30367264 )
2019
28
Genome-wide function of MCM-BP in Trypanosoma brucei DNA replication and transcription. ( 30407533 )
2019
29
The intron 3 16 bp duplication polymorphism of p53 (rs17878362) is not associated with increased risk of developing triple-negative breast cancer. ( 30430302 )
2019
30
Safety and Efficacy of Biodegradable Polymer-biolimus-eluting Stents (BP-BES) Compared with Durable Polymer-everolimus-eluting Stents (DP-EES) in Patients Undergoing Complex Percutaneous Coronary Intervention. ( 30468035 )
2019
31
Long-term relationship between unattended automated blood pressure and auscultatory BP measurements in hypertensive patients. ( 30474412 )
2019
32
BP neural network prediction model for suicide attempt among Chinese rural residents. ( 30599370 )
2019
33
Lower Systolic BP During Antihypertensive Treatment Associated with More Deaths in Older Adults. ( 30600978 )
2019
34
Development of specific fetometric formulas of ICC and BP for predicting the parturition date in Maine Coon queens. ( 30657609 )
2019
35
RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation. ( 30661983 )
2019
36
A Lung Sound Category Recognition Method Based on Wavelet Decomposition and BP Neural Network. ( 30662359 )
2019
37
Observation of ballistic avalanche phenomena in nanoscale vertical InSe/BP heterostructures. ( 30664752 )
2019
38
Efficacy and tolerability of BP-C1 in metastatic breast cancer: a Phase II, randomized, double-blind, and placebo-controlled Thai multi-center study. ( 30666153 )
2019
39
Identification of possible Δ14C anomalies since 14 ka BP: A computational intelligence approach. ( 30711582 )
2019
40
Labrador Sea freshening at 8.5 ka BP caused by Hudson Bay Ice Saddle collapse. ( 30718573 )
2019
41
The role of home BP monitoring: Answers to 10 common questions. ( 30724898 )
2019
42
A 4-bp deletion in the ASIP gene is associated with the recessive black coat colour in domestic guinea pigs (Cavia porcellus). ( 30746725 )
2019
43
Increased mitochondrial DNA4977-bp deletion in catheterization laboratory workers with long-term low-dose exposure to ionizing radiation. ( 30782005 )
2019
44
Impact of a 4-bp deletion variant (rs984225803) in the promoter region of SLC45A2 on color variation among a Japanese population. ( 30809845 )
2019
45
The further development of out-of-office BP monitoring: Japan's ImPACT Program Project's achievements, impact, and direction. ( 30811098 )
2019
46
The mitochondrial DNA 4977-bp deletion and copy number alteration in Han Chinese samples with uterine fibroids. ( 30821350 )
2019
47
First-Principles Investigation of the Adsorption Behaviors of CH₂O on BN, AlN, GaN, InN, BP, and P Monolayers. ( 30823524 )
2019
48
The Effect of Polyphenolic Composition BP-C3 on the Efficacy and Hematological Toxicity of Cyclophosphamide in the Chemotherapy of Mice Bearing Soft Tissue Sarcomas Induced by Benzo[a]pyrene. ( 30841763 )
2019
49
Risk assessment of earthquake network public opinion based on global search BP neural network. ( 30845195 )
2019
50
Fat regulates expression of four-jointed reporters in vivo through a 20 bp element independently of the Hippo pathway. ( 30858024 )
2019

Variations for Bowenoid Papulosis

Expression for Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for Bowenoid Papulosis

Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 34)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.64 CCND1 CCNE1 CDKN2A PTGS2
2
Show member pathways
12.63 CCND1 CCNE1 PTGS2 TERT
3
Show member pathways
12.45 CCND1 CCNE1 CDKN2A PPARG
4
Show member pathways
12.34 CCND1 CCNE1 CDKN2A TERT
5
Show member pathways
12.3 CCND1 CCNE1 CDKN2A
6 12.24 CCND1 CCNE1 CDKN2A
7 12.16 CCND1 CCNE1 PTGS2
8
Show member pathways
12.1 CCND1 CCNE1 CDKN2A
9 12.09 CCND1 CDKN2A TERT
10 12.07 CCND1 CCNE1 CDKN2A
11
Show member pathways
12.05 CCND1 CCNE1 CDKN2A
12
Show member pathways
12.01 CCND1 PPARG PTGS2
13 11.96 CCND1 CCNE1 CDKN2A
14 11.93 CCND1 CCNE1 CDKN2A PTGS2
15
Show member pathways
11.88 CCND1 CCNE1 CDKN2A
16 11.82 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
17 11.81 CCND1 CCNE1 CDKN2A
18
Show member pathways
11.72 CCND1 CCNE1 PTGS2
19
Show member pathways
11.54 PPARG PTGS2
20 11.54 CCND1 CCNE1 CDKN2A
21 11.52 CCND1 CDKN2A
22 11.51 PPARG PTGS2
23
Show member pathways
11.5 CCND1 CCNE1
24 11.47 CCND1 TERT
25
Show member pathways
11.44 CCND1 PTGS2
26 11.4 PPARG PTGS2
27 11.4 CCND1 CCNE1 PTGS2
28 11.38 CCNE1 PPARG
29 11.35 CCND1 PPARG
30 11.33 CCND1 PTGS2
31 11.32 CCND1 CCNE1
32 11.24 CCND1 CCNE1
33 11.07 CCND1 CCNE1
34 10.84 CCND1 CCNE1 CDKN2A

GO Terms for Bowenoid Papulosis

Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CCNE1

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.74 CDKN2A PPARG PTGS2
2 positive regulation of apoptotic process GO:0043065 9.69 CDKN2A PPARG PTGS2
3 response to drug GO:0042493 9.61 CCND1 PPARG PTGS2
4 regulation of protein stability GO:0031647 9.58 CDKN2A TERT
5 response to glucocorticoid GO:0051384 9.56 CCND1 PTGS2
6 response to estrogen GO:0043627 9.55 CCND1 PPARG
7 regulation of blood pressure GO:0008217 9.54 PPARG PTGS2
8 positive regulation of cell cycle GO:0045787 9.52 CCND1 CCNE1
9 regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 9.49 CCND1 CCNE1
10 animal organ regeneration GO:0031100 9.48 CCND1 PPARG
11 telomere maintenance GO:0000723 9.46 CCNE1 TERT
12 regulation of mitotic nuclear division GO:0007088 9.4 CCND1 CCNE1
13 positive regulation of G1/S transition of mitotic cell cycle GO:1900087 9.37 CCND1 TERT
14 response to organic cyclic compound GO:0014070 9.33 CCND1 PPARG PTGS2
15 response to organonitrogen compound GO:0010243 9.32 CCND1 PTGS2
16 replicative senescence GO:0090399 9.26 CDKN2A TERT
17 G1/S transition of mitotic cell cycle GO:0000082 9.13 CCND1 CCNE1 CDKN2A
18 response to organic substance GO:0010033 8.8 CCND1 PPARG PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.33 CCND1 PPARG PTGS2
2 transcription factor binding GO:0008134 9.13 CCND1 CDKN2A PPARG
3 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.62 CCND1 CCNE1

Sources for Bowenoid Papulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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