BP
MCID: BWN003
MIFTS: 42

Bowenoid Papulosis (BP)

Categories: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

MalaCards integrated aliases for Bowenoid Papulosis:

Name: Bowenoid Papulosis 53 73
Bp 53

Classifications:



External Ids:

UMLS 73 C0334106

Summaries for Bowenoid Papulosis

MalaCards based summary : Bowenoid Papulosis, also known as bp, is related to squamous cell carcinoma and cervical intraepithelial neoplasia. An important gene associated with Bowenoid Papulosis is CCND1 (Cyclin D1), and among its related pathways/superpathways are Human cytomegalovirus infection and PI3K-Akt signaling pathway. Affiliated tissues include heart, kidney and breast, and related phenotypes are Reduced mammosphere formation and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 76 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

Related Diseases for Bowenoid Papulosis

Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 290)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 30.8 CCND1 CDKN2A PTGS2
2 cervical intraepithelial neoplasia 30.2 CDKN2A TERT
3 papilloma 30.1 CCND1 CDKN2A FLG
4 nasopharyngeal carcinoma 29.2 CCND1 CDKN2A TERT
5 oral cancer 29.2 CCND1 CDKN2A PTGS2
6 gastric cancer 29.1 CCND1 CDKN2A PTGS2 TERT
7 hepatocellular carcinoma 28.6 CCND1 CDKN2A PTGS2 TERT
8 lung cancer 28.6 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
9 interstitial cystitis 12.0
10 bartsocas-papas syndrome 11.6
11 knuckle pads, leukonychia, and sensorineural deafness 11.1
12 growth hormone insensitivity with immunodeficiency 11.0
13 d-bifunctional protein deficiency 11.0
14 leukemia, chronic myeloid 11.0
15 vertebrobasilar insufficiency 11.0
16 bowen's disease 10.7
17 bullous pemphigoid 10.3
18 cystitis 10.3
19 acquired immunodeficiency syndrome 10.3
20 in situ carcinoma 10.3
21 clear cell adenocarcinoma of the ovary 10.2 CCND1 CCNE1
22 breast papillomatosis 10.2 CCND1 CDKN2A
23 tonsil squamous cell carcinoma 10.2 CCND1 CDKN2A
24 thalassemia 10.1
25 endometrial squamous cell carcinoma 10.1 CCND1 CDKN2A
26 ischemic fasciitis 10.1 CCND1 CDKN2A
27 verrucous carcinoma 10.1 CCND1 CDKN2A
28 pre-malignant neoplasm 10.1 CCND1 CDKN2A
29 chondromyxoid fibroma 10.1 CCND1 CDKN2A
30 laryngeal disease 10.1 CCND1 CDKN2A
31 oropharynx cancer 10.1 CCND1 CDKN2A
32 pharynx cancer 10.1 CCND1 CDKN2A
33 systemic lupus erythematosus 10.1
34 suppressor of tumorigenicity 3 10.1
35 dermatitis, atopic 10.1
36 leukemia 10.1
37 skin epithelioid hemangioma 10.1
38 dermatitis 10.1
39 hairy cell leukemia 10.1
40 lupus erythematosus 10.1
41 inverted papilloma 10.1 CCND1 CDKN2A
42 penile cancer 10.1 CCND1 CDKN2A
43 nasopharyngeal disease 10.1 CCND1 CDKN2A
44 retinal cancer 10.1 CCND1 CDKN2A
45 cervix disease 10.1 CCND1 CDKN2A
46 ocular cancer 10.1 CCND1 CDKN2A
47 recessive dystrophic epidermolysis bullosa 10.1 CDKN2A FLG
48 uterine anomalies 10.1 CCND1 CDKN2A
49 epstein-barr virus-associated gastric carcinoma 10.1 CDKN2A FLG
50 breast cancer 10.1

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to Bowenoid Papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

GenomeRNAi Phenotypes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.26 CCND1 CCNE1 PPARG PTGS2
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.17 CCNE1 CDKN2A TERT
3 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.17 CCND1 CCNE1 CDKN2A TERT

MGI Mouse Phenotypes related to Bowenoid Papulosis:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.99 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
2 endocrine/exocrine gland MP:0005379 9.95 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
3 growth/size/body region MP:0005378 9.93 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
4 hematopoietic system MP:0005397 9.91 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
5 digestive/alimentary MP:0005381 9.89 CCND1 CCNE1 CDKN2A PTGS2 TERT
6 immune system MP:0005387 9.88 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
7 neoplasm MP:0002006 9.8 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
8 integument MP:0010771 9.77 CCND1 CCNE1 CDKN2A PPARG PTGS2
9 nervous system MP:0003631 9.73 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
10 normal MP:0002873 9.55 CCND1 CCNE1 PPARG PTGS2 TERT
11 reproductive system MP:0005389 9.43 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
12 skeleton MP:0005390 9.1 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT

Drugs & Therapeutics for Bowenoid Papulosis

Search Clinical Trials , NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

MalaCards organs/tissues related to Bowenoid Papulosis:

41
Heart, Kidney, Breast, Skin, Lung, Liver, Myeloid

Publications for Bowenoid Papulosis

Articles related to Bowenoid Papulosis:

(show top 50) (show all 931)
# Title Authors Year
1
Erratum: Novel 4-bp Intronic Deletion (c.1560+3_1560+6del) in LEMD3 in a Korean Patient With Osteopoikilosis. ( 30430792 )
2019
2
Genital bowenoid papulosis: the variegated dermoscopic features. ( 29767494 )
2018
3
Korean Medication Algorithm Project for Bipolar Disorder 2018 (KMAP-BP 2018): Fourth Revision. ( 30466216 )
2018
4
Evaluation of 4-bp insertion/deletion polymorphism within the 3'UTR of SGSM3 in bladder cancer using mismatch PCR-RFLP method: A preliminary report. ( 29693742 )
2018
5
Epidermal mast cells in Bowenoid papulosis during topical imiquimod therapy. ( 30204264 )
2018
6
Ghrelin Ameliorates Traumatic Brain Injury by Down-Regulating bFGF and FGF-BP. ( 30026681 )
2018
7
The intron 3 16 bp duplication polymorphism of p53 (rs17878362) is not associated with increased risk of developing triple-negative breast cancer. ( 30430302 )
2018
8
Pathobiological and Genomic Characterization of a Cold-Adapted Infectious Bronchitis Virus (BP-caKII). ( 30463206 )
2018
9
The incidence of herpes zoster in cutaneous lupus erythematosus (CLE), dermatomyositis (DM), pemphigus vulgaris (PV), and bullous pemphigoid (BP). ( 30521827 )
2018
10
Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT. ( 30371182 )
2018
11
Characterization of a human induced Pluripotent Stem (iPS) cell line (INCABRi002-A) derived from a primary myelofibrosis patient harboring the 5-bp insertion in CALR and the p.W146X mutation in TP53. ( 30343103 )
2018
12
Human leucocyte antigen-G 14-bp InDel polymorphism and oral squamous cell carcinoma risk in Chinese Han population: A case-control study. ( 30030939 )
2018
13
Oral implant survival in patients with bisphosphonate (BP)/antiresorptive and radiation therapy and their impact on osteonecrosis of the jaws. A systematic review. ( 30109302 )
2018
14
Bordetella pertussis (Bp) disease: Before (2003-2011) and after (2013-2016) maternal immunization strategy in a pediatric hospital. ( 29429812 )
2018
15
Association of VDR gene polymorphisms and 22 bp deletions in the promoter region of TLR2Δ22 (-196-174) with increased risk of pulmonary tuberculosis: A case-control study in tea garden communities of Assam. ( 29727015 )
2018
16
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea. ( 29951886 )
2018
17
A biallelic 36-bp insertion in PIBF1 is associated with Joubert syndrome. ( 29695797 )
2018
18
A 4-bp deletion promoter variant (rs984225803) is associated with mild OCA4 among Japanese patients. ( 30019506 )
2018
19
Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer. ( 29779135 )
2018
20
A novel 8-bp duplication in ADAT3 causes mild intellectual disability. ( 29796286 )
2018
21
Does self-monitoring and self-management of blood pressure after stroke or transient ischemic attack improve control? TEST-BP, a randomized controlled trial. ( 30060882 )
2018
22
Correction to: Lack of relationship between PTEN 32-bp and TP53 16-bp Ins/Del polymorphisms and chronic hepatitis B virus infection. ( 29608185 )
2018
23
Meta-analysis of correlationship between HLA-G 3'UTR 14-bp Ins/Del polymorphism and virus susceptibility. ( 30235670 )
2018
24
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis. ( 30138450 )
2018
25
Performance evaluation of fuzzy-logic and BP-ANN methods for WEDM of aeronautics super alloy. ( 30151349 )
2018
26
Translation into Portuguese language (Brazil), transcultural adaptation and validation of the quality of life questionnaire in female pattern hair loss (WAA-QoL-BP). ( 30156620 )
2018
27
Ultrahigh-photoresponsive UV photodetector based on a BP/ReS2 heterostructure p-n diode. ( 30160292 )
2018
28
The comparison of early healing 1-month after PCI among CoCr-everolimus-eluting stent (EES), biodegradable polymer (BP)-EES and BP-sirolimus-eluting stent: Insights from OFDI and coronary angioscopy. ( 30167453 )
2018
29
Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. ( 30190611 )
2018
30
Validation of the A&D BP UA-1200BLE device for home blood pressure measurement according to the ISO 81060-2: 2013 standard. ( 30199378 )
2018
31
Association between 14 bp insertion/deletion HLA-G functional polymorphism and insulin resistance in a cohort of Italian children with obesity. ( 30203576 )
2018
32
Peridialysis BP levels and risk of all-cause mortality: a dose-response meta-analysis. ( 30209306 )
2018
33
Review: In hypertension, intensive BP goals reduce CV events; self vs office BP measures do not improve BP at 12 mo. ( 30242399 )
2018
34
Risk Evaluation Model of Highway Tunnel Portal Construction Based on BP Fuzzy Neural Network. ( 30245709 )
2018
35
A Novel F3' 5' H Allele with 14 bp Deletion Is Associated with High Catechin Index Trait of Wild Tea Plants and Has Potential Use in Enhancing Tea Quality. ( 30253089 )
2018
36
Unobserved automated office BP is similar to other clinic BP measurements: A prospective randomized study. ( 30272388 )
2018
37
Correction: Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype-phenotype correlation. ( 30275510 )
2018
38
In response to letter: OSA and BP: Too good to be true? ( 30284260 )
2018
39
Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos. ( 30300651 )
2018
40
Operation Mechanism of a MoS₂/BP Heterojunction FET. ( 30301261 )
2018
41
A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of ENCODE/Broad ChromHMM Annotations: A Computational Perspective. ( 30309205 )
2018
42
No association of TP53 codon 72 and intron 3 16-bp duplication polymorphisms with breast cancer risk in Chinese Han women: new evidence from a population-based case-control investigation. ( 30309383 )
2018
43
Validation of the Welch Allyn Pro BP 2000, a professional-grade inflation-based automated sphygmomanometer with arrhythmia detection in a combined pediatric and adult population by ANSI/AAMI/ISO standard testing. ( 30312180 )
2018
44
Effects of DRD2 splicing-regulatory polymorphism and DRD4 48 bp VNTR on crack cocaine addiction. ( 30367264 )
2018
45
Genome-wide function of MCM-BP in Trypanosoma brucei DNA replication and transcription. ( 30407533 )
2018
46
Detection of Toxoplasma gondii copro-prevalence by polymerase chain reaction using repetitive 529 bp gene in feces of pet cats (Felis catus) in Yogyakarta, Indonesia. ( 30410243 )
2018
47
The genetic prehistory of the Andean highlands 7000 years BP though European contact. ( 30417096 )
2018
48
Decoupling Research of a Novel Three-Dimensional Force Flexible Tactile Sensor Based on an Improved BP Algorithm. ( 30424169 )
2018
49
FBCSP-based Multi-class Motor Imagery Classification using BP and TDP features. ( 30440376 )
2018
50
Home blood pressure control status in 2017-2018 for hypertension specialist centers in Asia: Results of the Asia BP@Home study. ( 30444315 )
2018

Variations for Bowenoid Papulosis

Expression for Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for Bowenoid Papulosis

Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 35)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.73 CCND1 CCNE1 CDKN2A PTGS2
2
Show member pathways
12.64 CCND1 CCNE1 PTGS2 TERT
3
Show member pathways
12.45 CCND1 CCNE1 CDKN2A PPARG
4
Show member pathways
12.34 CCND1 CCNE1 CDKN2A TERT
5
Show member pathways
12.31 CCND1 CCNE1 CDKN2A
6 12.25 CCND1 CCNE1 CDKN2A
7 12.17 CCND1 CCNE1 PTGS2
8
Show member pathways
12.17 CCND1 CCNE1 CDKN2A
9 12.16 CCND1 CDKN2A TERT
10
Show member pathways
12.1 CCND1 CCNE1 CDKN2A
11 12.07 CCND1 CCNE1 CDKN2A
12
Show member pathways
12.05 CCND1 CCNE1 CDKN2A
13
Show member pathways
12.01 CCND1 PPARG PTGS2
14 11.96 CCND1 CCNE1 CDKN2A
15 11.93 CCND1 CCNE1 CDKN2A PTGS2
16
Show member pathways
11.88 CCND1 CCNE1 CDKN2A
17 11.82 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
18 11.81 CCND1 CCNE1 CDKN2A
19
Show member pathways
11.72 CCND1 CCNE1 PTGS2
20
Show member pathways
11.55 PPARG PTGS2
21 11.54 CCND1 CCNE1 CDKN2A
22 11.53 CCND1 CDKN2A
23 11.51 PPARG PTGS2
24
Show member pathways
11.5 CCND1 CCNE1
25 11.47 CCND1 TERT
26
Show member pathways
11.45 CCND1 PTGS2
27 11.41 PPARG PTGS2
28 11.4 CCND1 CCNE1 PTGS2
29 11.39 CCNE1 PPARG
30 11.36 CCND1 PPARG
31 11.34 CCND1 PTGS2
32 11.32 CCND1 CCNE1
33 11.25 CCND1 CCNE1
34 11.07 CCND1 CCNE1
35 10.84 CCND1 CCNE1 CDKN2A

GO Terms for Bowenoid Papulosis

Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CCNE1

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.74 CDKN2A PPARG PTGS2
2 positive regulation of apoptotic process GO:0043065 9.69 CDKN2A PPARG PTGS2
3 response to drug GO:0042493 9.61 CCND1 PPARG PTGS2
4 regulation of protein stability GO:0031647 9.58 CDKN2A TERT
5 response to glucocorticoid GO:0051384 9.56 CCND1 PTGS2
6 response to estrogen GO:0043627 9.55 CCND1 PPARG
7 regulation of blood pressure GO:0008217 9.54 PPARG PTGS2
8 positive regulation of cell cycle GO:0045787 9.52 CCND1 CCNE1
9 regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 9.49 CCND1 CCNE1
10 animal organ regeneration GO:0031100 9.48 CCND1 PPARG
11 telomere maintenance GO:0000723 9.46 CCNE1 TERT
12 regulation of mitotic nuclear division GO:0007088 9.4 CCND1 CCNE1
13 positive regulation of G1/S transition of mitotic cell cycle GO:1900087 9.37 CCND1 TERT
14 response to organic cyclic compound GO:0014070 9.33 CCND1 PPARG PTGS2
15 response to organonitrogen compound GO:0010243 9.32 CCND1 PTGS2
16 replicative senescence GO:0090399 9.26 CDKN2A TERT
17 G1/S transition of mitotic cell cycle GO:0000082 9.13 CCND1 CCNE1 CDKN2A
18 response to organic substance GO:0010033 8.8 CCND1 PPARG PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.43 CCND1 PPARG PTGS2
2 transcription factor binding GO:0008134 9.33 CCND1 CDKN2A PPARG
3 cyclin-dependent protein serine/threonine kinase activity GO:0004693 8.96 CCND1 CCNE1
4 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.62 CCND1 CCNE1

Sources for Bowenoid Papulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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