MCID: BRC002
MIFTS: 30

Brachial Plexus Neuritis

Categories: Neuronal diseases

Aliases & Classifications for Brachial Plexus Neuritis

MalaCards integrated aliases for Brachial Plexus Neuritis:

Name: Brachial Plexus Neuritis 12 15 17 72
Parsonage-Aldren-Turner Syndrome 12
Brachial Neuritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3689
MeSH 44 D020968
NCIt 50 C84600
ICD10 33 G54.5
UMLS 72 C0221759

Summaries for Brachial Plexus Neuritis

MalaCards based summary : Brachial Plexus Neuritis, also known as parsonage-aldren-turner syndrome, is related to peripheral nervous system disease and neuromuscular disease. An important gene associated with Brachial Plexus Neuritis is BLOC1S6 (Biogenesis Of Lysosomal Organelles Complex 1 Subunit 6), and among its related pathways/superpathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and B Cell Development Pathways. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include myeloid, and related phenotypes are Mildly decreased CFP-tsO45G cell surface transport and mortality/aging

Related Diseases for Brachial Plexus Neuritis

Diseases related to Brachial Plexus Neuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 peripheral nervous system disease 30.1 MUSK MTM1 DNM2
2 neuromuscular disease 29.4 MUSK MTM1
3 amyotrophic neuralgia 12.1
4 amyotrophy, hereditary neuralgic 12.0
5 parsonage turner syndrome 11.9
6 radiation induced brachial plexopathy 11.5
7 neuritis 10.8
8 myopathy, centronuclear, x-linked 10.4 MTM1 DNM2
9 charcot-marie-tooth disease, dominant intermediate b 10.3 MTM1 DNM2
10 gonadal dysgenesis 10.3
11 turner syndrome 10.3
12 plexopathy 10.3
13 centronuclear myopathy 10.2 MTM1 DNM2
14 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2
15 herpes zoster 10.2
16 vasculitis 10.2
17 chickenpox 10.2
18 neuropathy 10.2
19 myopathy, congenital 10.2 MTM1 DNM2
20 cleft palate, isolated 10.0
21 myasthenia gravis 10.0
22 leukemia, acute myeloid 10.0
23 aceruloplasminemia 10.0
24 tetanus 10.0
25 allergic hypersensitivity disease 10.0
26 polyneuropathy 10.0
27 lymphadenitis 10.0
28 endometriosis 10.0
29 brachial plexus neuropathy 10.0
30 myopathy 10.0
31 radiculopathy 10.0
32 rhinitis 10.0
33 erythema infectiosum 10.0
34 hypersensitivity vasculitis 10.0
35 hypereosinophilic syndrome 10.0
36 kikuchi disease 10.0
37 cytomegalovirus infection 10.0
38 hematopoietic stem cell transplantation 10.0
39 pfeiffer syndrome 10.0
40 cervical rib 10.0
41 pertussis 10.0
42 diphtheria 10.0
43 guillain-barre syndrome 10.0
44 thoracic outlet syndrome 10.0
45 autoimmune disease of musculoskeletal system 10.0 MUSK CD40LG
46 spondylosis, cervical 9.9
47 immune deficiency disease 9.9
48 myeloma, multiple 9.9
49 exanthem 9.9
50 cervical dystonia 9.9

Graphical network of the top 20 diseases related to Brachial Plexus Neuritis:



Diseases related to Brachial Plexus Neuritis

Symptoms & Phenotypes for Brachial Plexus Neuritis

GenomeRNAi Phenotypes related to Brachial Plexus Neuritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Mildly decreased CFP-tsO45G cell surface transport GR00360-A-1 9.17 BLOC1S6 CD40LG DNM2 FOXL2 GPT PDCD1

MGI Mouse Phenotypes related to Brachial Plexus Neuritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.76 BLOC1S6 CD40LG DNM2 FOXL2 MTM1 MUSK
2 muscle MP:0005369 9.35 BLOC1S6 DNM2 MTM1 MUSK PDCD1
3 skeleton MP:0005390 9.1 BLOC1S6 CD40LG GPT MTM1 MUSK PDCD1

Drugs & Therapeutics for Brachial Plexus Neuritis

Drugs for Brachial Plexus Neuritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2 Cholinergic Agents Phase 4
3 Neurotransmitter Agents Phase 4
4 Acetylcholine Release Inhibitors Phase 4
5 Botulinum Toxins Phase 4
6
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
7 Analgesics Phase 2, Phase 3
8 Cyclooxygenase Inhibitors Phase 2, Phase 3
9 Analgesics, Non-Narcotic Phase 2, Phase 3
10 Peripheral Nervous System Agents Phase 2, Phase 3
11 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3
12 Anti-Inflammatory Agents Phase 2, Phase 3
13 Antirheumatic Agents Phase 2, Phase 3
14 Immunologic Factors
15 Vaccines

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Probe Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
2 Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain Completed NCT02593721 Phase 2, Phase 3 Ibuprofen
3 Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02596815 Phase 2
4 Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group Completed NCT02595294 Phase 2
5 Longitudinal Experimental Study on ULNTT1 and Cervico-Thoracic Spine Motion Patterns Relationship Completed NCT02632357
6 The GRANVIA®-C Cervical Disc Prosthesis to Treat Symptomatic Degenerative Disc Diseases Completed NCT01518582
7 A Phase IV Study to Assess the Safety of Menveo Vaccine Being Used by HMO Subjects Aged 11-21 Years of Age Completed NCT01452464
8 Cervicobrachial Neuralgia and Sagital Balance of the Cervical Spine Recruiting NCT03397459
9 Neuralgic Amyotrophy: Central Reorganization and Rehabilitation After Peripheral Dysfunction Enrolling by invitation NCT03441347

Search NIH Clinical Center for Brachial Plexus Neuritis

Genetic Tests for Brachial Plexus Neuritis

Anatomical Context for Brachial Plexus Neuritis

MalaCards organs/tissues related to Brachial Plexus Neuritis:

41
Myeloid

Publications for Brachial Plexus Neuritis

Articles related to Brachial Plexus Neuritis:

(show top 50) (show all 56)
# Title Authors PMID Year
1
Visceral disseminated varicella zoster virus infection with brachial plexus neuritis detected by fluorodeoxyglucose positron emission tomography and computed tomography. 38
30879980 2019
2
Immune-mediated neurological manifestations of dengue virus- a study of clinico-investigational variability, predictors of neuraxial involvement, and outcome with the role of immunomodulation. 38
30504556 2018
3
Chronic Brachial Plexus Neuritis That Developed into Typical Neuralgic Amyotrophy and Positively Responded to Immunotherapy. 38
29269655 2018
4
Brachial Plexus Neuritis Associated With Anti-Programmed Cell Death-1 Antibodies: Report of 2 Cases. 38
30225416 2017
5
Neuralgic Amyotrophy Attributed Incorrectly to Block-Related Injury: Understanding Errors in Clinical Reasoning. 38
28665875 2017
6
A case of relapsing-remitting facial palsy and ipsilateral brachial plexopathy caused by HSV-1. 38
26991053 2016
7
[Bilateral diaphragmatic paralysis due to Parsonage-Turner syndrome]. 38
25534571 2015
8
A novel dynamin-2 gene mutation associated with a late-onset centronuclear myopathy with necklace fibres. 38
25633151 2015
9
Idiopathic brachial neuritis in a child: A case report and review of the literature. 38
25624937 2014
10
Brachial Plexus Neuritis Associated With Streptococcus agalactiae Infection: A Case Report. 38
25229037 2014
11
Brachial Neuritis With Phrenic Nerve Involvement in a Patient With a Possible Connective Tissue Disease. 38
26425609 2014
12
Fascicular thickening of the median nerve detected by sonography in an anterior interosseous syndrome as a brachial plexus neuritis. 38
24095152 2014
13
Idiopathic brachial plexus neuritis after laparoscopic treatment of endometriosis: a complication that may mimic position-related brachial plexus injury. 38
24183278 2013
14
Dysphonia as an unusual debut of Parsonage-Turner syndrome. 38
22887078 2013
15
Brachial Plexopathy due to Myeloid Sarcoma in a Patient With Acute Myeloid Leukemia After Allogenic Peripheral Blood Stem Cell Transplantation. 38
23705126 2013
16
Recurrent vocal fold paralysis and parsonage-turner syndrome. 38
24288639 2013
17
[Pathogenesis and treatment of brachial plexus neuritis]. 38
24291849 2013
18
Neuralgic amyotrophy (Parsonage-Turner syndrome). 38
22751163 2012
19
Brachial plexus neuritis in the context of acute HIV seroconversion illness: a case report. 38
22422693 2012
20
Clinical and pathophysiological concepts of neuralgic amyotrophy. 38
21556032 2011
21
Teaching NeuroImages: MRI findings in varicella zoster brachial plexus neuritis. 38
21482943 2011
22
An unusual case of neuralgic amyotrophy presenting with bilateral phrenic nerve and vocal cord paresis. 38
21490716 2011
23
Idiopathic brachial neuritis. 38
19927060 2009
24
Pure motor Herpes Zoster induced brachial plexopathy. 38
19434442 2009
25
Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis). 38
19588414 2009
26
Brachial plexus neuritis following HPV vaccination. 38
18602437 2008
27
Kiloh-Nevin syndrome: a compression neuropathy or brachial plexus neuritis? 38
17715720 2007
28
Brachial plexus neuritis: is prognosis worse in children? 38
15120689 2004
29
Distinctive imaging evidence of brachial plexus neuritis demonstrated on Ga-67 citrate scintigraphy. 38
12544147 2003
30
[Scapula alata as a complication of infection with human parvovirus B19 (erythema infectiosum)]. 38
11386110 2001
31
Acute brachial plexus neuritis: an uncommon cause of shoulder pain. 38
11087188 2000
32
Viral brachial neuritis in emergency medicine. 38
10699518 2000
33
Transfer of flexor carpi ulnaris branch of the ulnar nerve to the pronator teres nerve: histomorphometric analysis. 38
10088923 1999
34
[A case of subacute necrotizing lymphadenitis complicated with brachial plexus neuritis]. 38
10203979 1998
35
Brachial neuritis presenting as anterior interosseous nerve compression--implications for diagnosis and treatment: a case report. 38
9195467 1997
36
Herpes zoster brachial plexus neuritis. 38
9101105 1997
37
Bilateral brachial plexus neuritis following parvovirus B19 and cytomegalovirus infection. 38
9007101 1996
38
Isolated suprascapular nerve palsy: a review of nine cases. 38
8599775 1995
39
[Monoparesis due to the brachial plexus neuritis by herpes zoster virus--report of a case]. 38
1813197 1991
40
Hypertrophic brachial plexus neuritis: a pathological study of two cases. 38
3202614 1988
41
Brachial plexus neuritis and recurrent laryngeal nerve palsy. 38
3385453 1988
42
Craniolateral approach to the canine brachial plexus. 38
3256140 1988
43
Acute bilateral brachial plexus neuritis associated with hypersensitivity vasculitis. A case report and review of literature. 38
4032989 1985
44
Brachial neuritis in salmonellosis. 38
6512573 1984
45
Brachial plexus neuritis and fatal hemorrhage following Aspergillus infection of a Hickman catheter. 38
6955001 1982
46
Neurological complications of immunization. 38
6751212 1982
47
Lumbosacral plexus neuritis. 38
7194440 1981
48
[Painless brachial plexus neuritis (author's transl)]. 38
450882 1979
49
[Brachial plexus neuritis may be painless and a good indication for surgery (authors transl)]. 38
834728 1977
50
Cryptogenic infraclavicular brachial plexus neuritis: (preliminary report). 38
1028516 1976

Variations for Brachial Plexus Neuritis

Expression for Brachial Plexus Neuritis

Search GEO for disease gene expression data for Brachial Plexus Neuritis.

Pathways for Brachial Plexus Neuritis

Pathways related to Brachial Plexus Neuritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.72 PDCD1 CD40LG
2 10.35 PDCD1 CD40LG

GO Terms for Brachial Plexus Neuritis

Biological processes related to Brachial Plexus Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.13 PDCD1 FOXL2 DNM2
2 T cell costimulation GO:0031295 8.62 PDCD1 CD40LG

Sources for Brachial Plexus Neuritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
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42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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