MCID: BRN008
MIFTS: 29

Brain Compression

Categories: Neuronal diseases

Aliases & Classifications for Brain Compression

MalaCards integrated aliases for Brain Compression:

Name: Brain Compression 12 15
Compression of Brain 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:11457
ICD9CM 34 348.4
SNOMED-CT 67 46963008
ICD10 32 G93.5
UMLS 71 C0009592

Summaries for Brain Compression

Disease Ontology : 12 A brain disease that is characterized by pressure on the intracranial tissues by an effusion of blood or cerebrospinal fluid, an abscess, a neoplasm, a depressed fracture of the skull, or edema of the brain.

MalaCards based summary : Brain Compression, also known as compression of brain, is related to intracranial hypertension and hydrops, lactic acidosis, and sideroblastic anemia. An important gene associated with Brain Compression is MIA2 (MIA SH3 Domain ER Export Factor 2). The drugs tannic acid and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and pituitary.

Related Diseases for Brain Compression

Diseases related to Brain Compression via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 intracranial hypertension 9.9
2 hydrops, lactic acidosis, and sideroblastic anemia 9.8
3 brain edema 9.8
4 hydrocephalus, congenital, 1 9.6
5 hypervitaminosis a 9.6
6 moyamoya disease 1 9.6
7 ocular motor apraxia 9.6
8 meningioma, radiation-induced 9.6
9 meningioma, familial 9.6
10 deficiency anemia 9.6
11 cardiac arrest 9.6
12 disseminated intravascular coagulation 9.6
13 spinal meningioma 9.6
14 secretory meningioma 9.6
15 lymphoplasmacyte-rich meningioma 9.6
16 48,xyyy 9.6
17 paresthesia 9.6
18 actinomycosis 9.6 WRNIP1 HCCS

Comorbidity relations with Brain Compression via Phenotypic Disease Network (PDN):


Brain Edema Hypertension, Essential
Obstructive Hydrocephalus

Graphical network of the top 20 diseases related to Brain Compression:



Diseases related to Brain Compression

Symptoms & Phenotypes for Brain Compression

Drugs & Therapeutics for Brain Compression

Drugs for Brain Compression (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
tannic acid Approved Phase 3 1401-55-4
2
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
3
Tranexamic Acid Approved Phase 3 1197-18-8 5526
4
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
5 Calcium, Dietary Phase 3
6 diuretics Phase 3
7 Angiotensin-Converting Enzyme Inhibitors Phase 3
8 calcium channel blockers Phase 3
9 Antihypertensive Agents Phase 3
10 Hemostatics Phase 3
11 Coagulants Phase 3
12 Antifibrinolytic Agents Phase 3
13
Curcumin Approved, Experimental, Investigational Early Phase 1 458-37-7 969516
14
Turmeric Approved, Experimental, Investigational Early Phase 1
15 Anti-Inflammatory Agents Early Phase 1
16 Anti-Inflammatory Agents, Non-Steroidal Early Phase 1
17 Analgesics, Non-Narcotic Early Phase 1
18 Antioxidants Early Phase 1
19 Protective Agents Early Phase 1
20 Antirheumatic Agents Early Phase 1
21 Analgesics Early Phase 1
22 Turmeric extract Early Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 China Antihypertensive Trial in Acute Ischemic Stroke II Recruiting NCT03479554 Phase 3
2 Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma. A Double-blind, Placebo-controlled, Multicentre, Randomized Controlled Clinical Trial Recruiting NCT03582293 Phase 3 Tranexamic Acid 500Mg Tablet;Placebo oral capsule
3 Clinical Action of Curcumin/Turmeric in Chronic Subdural Hematoma Recurrence Recruiting NCT03845322 Early Phase 1 Curcumin Pill;Placebo pills
4 Association Between Haptoglobin Genotype and the Development of Perihematomal Edema After Spontaneous Intracerebral Hemorrhage Terminated NCT02054117
5 Preliminary Investigation of ViaShield™ Amnion Patch as an Anti-Adhesive Barrier in Hemicraniectomies Withdrawn NCT03371316

Search NIH Clinical Center for Brain Compression

Genetic Tests for Brain Compression

Anatomical Context for Brain Compression

MalaCards organs/tissues related to Brain Compression:

40
Brain, Bone, Pituitary, Eye, Cortex, Thyroid, Skin

Publications for Brain Compression

Articles related to Brain Compression:

(show top 50) (show all 201)
# Title Authors PMID Year
1
Brain Compression by Encephalo-Myo-Synangiosis is a Risk Factor for Transient Neurological Deficits After Surgical Revascularization in Pediatric Patients with Moyamoya Disease. 61
31562963 2020
2
Neurological abnormalities in 97 dogs with detectable pituitary masses. 61
31112462 2019
3
A microfabricated, 3D-sharpened silicon shuttle for insertion of flexible electrode arrays through dura mater into brain. 61
31216526 2019
4
Head of the Bed Down: Paradoxical Management for Paradoxical Herniation. 61
31403093 2019
5
Spontaneous Subdural Hematoma in Patient with Polycythemia Vera. 61
30780039 2019
6
Case-based review: atypical teratoid/rhabdoid tumor. 61
31386032 2019
7
Detection and Evaluation of Intracranial Aneurysms in the Posterior Fossa by Multidetector Computed Tomography Angiography - Comparison with Digital Subtraction Angiography. 61
31143268 2019
8
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium. 61
30948807 2019
9
Prediction of probability of fatality due to brain injury in traffic accidents. 61
31381455 2019
10
Cerebral Edema and Elevated Intracranial Pressure. 61
30516597 2018
11
Nanoscale mechanics of brain abscess: An atomic force microscopy study. 61
29957562 2018
12
Direct visualization of microcirculation impairment after acute subdural hemorrhage in a novel animal model. 61
29219760 2018
13
Rapid increase of 'brain-type' transferrin in cerebrospinal fluid after shunt surgery for idiopathic normal pressure hydrocephalus: a prognosis marker for cognitive recovery. 61
29701803 2018
14
Intracranial Hematopoiesis in Beta Thalassemia: A Case Series. 61
29368108 2018
15
Bone flap elevation for intracranial EEG monitoring: technical note. 61
28946179 2018
16
An extremely rare giant skin cirsoid angioma with brain compression. 61
29507133 2018
17
A Rare Case of Composite Dural Extranodal Marginal Zone Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. 61
29740389 2018
18
[Invasive sinonasal papilloma with intracranial invasion: Case report and bibliographic review]. 61
29430328 2018
19
Cerebral Arterial Compliance in Traumatic Brain Injury. 61
29492525 2018
20
Brain metastasis: clinical manifestations, symptom management, and palliative care. 61
29307363 2018
21
Hyponatremia and the Brain. 61
29340311 2018
22
Calcified cephalohematoma as an unusual cause of EEG anomalies: case report. 61
27715482 2017
23
Development of acute hydrocephalus does not change brain tissue mechanical properties in adult rats, but in juvenile rats. 61
28837671 2017
24
To Retain or Remove the Bone Flap During Evacuation of Acute Subdural Hematoma: Factors Associated with Perioperative Brain Edema. 61
27476687 2016
25
Density measurements with computed tomography in patients with extra-axial hematoma can quantitatively estimate a degree of brain compression. 61
27385774 2016
26
Early Decompression of Acute Subdural Hematoma for Postoperative Neurological Improvement: A Single Center Retrospective Review of 10 Years. 61
27182496 2016
27
Calvarial bone cavernous hemangioma with intradural invasion: An unusual aggressive course-Case report and literature review. 61
27061482 2016
28
[Extensive cranioplasty for sagittal synostosis in young children by preserving multiple cranial bone flaps adhered to the dura mater: experience with 63 cases]. 61
27197472 2016
29
Improving hospital death certification in Viet Nam: results of a pilot study implementing an adapted WHO hospital death report form in two national hospitals. 61
28588910 2016
30
Outcome of surgery for operable supratentorial mass lesions in patients presenting with decerebration following severe head injury: A retrospective analysis of factors affecting outcome. 61
26396598 2015
31
Candida Albicans Dural Granuloma: Case Report. 61
28663966 2015
32
Extensive cranioplasty for sagittal synostosis in young children by preserving cranial bone flaps adhered to the dura mater. 61
25668119 2015
33
Outcome of 12 antenatally diagnosed fetal arachnoid cysts: case series and review of the literature. 61
25599983 2015
34
Detection of third and sixth cranial nerve palsies with a novel method for eye tracking while watching a short film clip. 61
25495739 2015
35
Neural oscillation, network, eloquent cortex and epileptogenic zone revealed by magnetoencephalography and awake craniotomy. 61
25685205 2014
36
[Postmortem assessment of labor from changes in the skull and brain in fetuses and newborn infants]. 61
25306615 2014
37
Zolpidem arouses patients in vegetative state after brain injury: quantitative evaluation and indications. 61
23462249 2014
38
Chronic subdural hematoma in elderly patient with EDTA-dependent pseudothrombocytopenia recently treated with aspirin and warfarin: case report. 61
24477063 2014
39
Endoscopic surgery for traumatic acute subdural hematoma. 61
24659965 2013
40
Extracranial expansion of a feline meningioma. 61
23295269 2013
41
Observations of changes of blood pressure before and after neurosurgical decompression in hypertensive patients with different types of neurovascular compression of brain stem. 61
24247558 2013
42
Determination of friction coefficient in unconfined compression of brain tissue. 61
23026694 2012
43
Posterior cranial vault expansion in the treatment of craniosynostosis. Comparison of current techniques. 61
22872270 2012
44
Atypical scaphocephaly: a review. 61
22872243 2012
45
Quantitative immunohistochemical analysis of human brain basic fibroblast growth factor, glial fibrillary acidic protein and single-stranded DNA expressions following traumatic brain injury. 61
22607979 2012
46
Elevated diffusion anisotropy in gray matter and the degree of brain compression. 61
22680241 2012
47
[Intracranial, cerebral perfusion pressure and systemic hemodynamic parameters during anesthesia induction in patients with traumatic brain compression]. 61
23082647 2012
48
[Syndrome of brain compression in cranio-cerebral trauma]. 61
23488267 2012
49
Microscopic magnetic resonance elastography of traumatic brain injury model. 61
21871490 2011
50
Intradiploic epidermoid cyst of the temporal bone: is it the same as or different from cholesteatoma? 61
21959487 2011

Variations for Brain Compression

Expression for Brain Compression

Search GEO for disease gene expression data for Brain Compression.

Pathways for Brain Compression

GO Terms for Brain Compression

Sources for Brain Compression

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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