MCID: BRN008
MIFTS: 25

Brain Compression

Categories: Neuronal diseases

Aliases & Classifications for Brain Compression

MalaCards integrated aliases for Brain Compression:

Name: Brain Compression 12 15
Compression of Brain 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11457
ICD9CM 36 348.4
SNOMED-CT 69 46963008
ICD10 34 G93.5
UMLS 74 C0009592

Summaries for Brain Compression

Disease Ontology : 12 A brain disease that is characterized by pressure on the intracranial tissues by an effusion of blood or cerebrospinal fluid, an abscess, a neoplasm, a depressed fracture of the skull, or edema of the brain.

MalaCards based summary : Brain Compression, also known as compression of brain, is related to hemopneumothorax and sphenoid sinusitis. An important gene associated with Brain Compression is HCCS (Holocytochrome C Synthase), and among its related pathways/superpathways are Endochondral Ossification and Cell adhesion_Plasmin signaling. Affiliated tissues include brain, skin and thyroid, and related phenotype is homeostasis/metabolism.

Related Diseases for Brain Compression

Diseases related to Brain Compression via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hemopneumothorax 10.1 AVP HCCS
2 sphenoid sinusitis 10.0 AVP GJB6
3 vestibular disease 10.0 AVP GJB6
4 adhesive otitis media 9.9 FGF2 PLAT
5 space motion sickness 9.8 AVP FGF2
6 carotid artery dissection 9.8 AVP PLAT
7 posterior myocardial infarction 9.8 PLAT WRNIP1
8 keratitis, hereditary 9.7 FGF2 GJB6
9 hypervitaminosis a 9.6

Comorbidity relations with Brain Compression via Phenotypic Disease Network (PDN):


Brain Edema Hypertension, Essential
Obstructive Hydrocephalus

Graphical network of the top 20 diseases related to Brain Compression:



Diseases related to Brain Compression

Symptoms & Phenotypes for Brain Compression

MGI Mouse Phenotypes related to Brain Compression:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.17 AVP FGF2 GJB6 HCCS PLAT POLK

Drugs & Therapeutics for Brain Compression

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Association Between Haptoglobin Genotype and Brain Swelling Terminated NCT02054117

Search NIH Clinical Center for Brain Compression

Genetic Tests for Brain Compression

Anatomical Context for Brain Compression

MalaCards organs/tissues related to Brain Compression:

42
Brain, Skin, Thyroid

Publications for Brain Compression

Articles related to Brain Compression:

(show all 35)
# Title Authors Year
1
An extremely rare giant skin cirsoid angioma with brain compression. ( 29507133 )
2018
2
Density measurements with computed tomography in patients with extra-axial hematoma can quantitatively estimate a degree of brain compression. ( 27385774 )
2016
3
Observations of changes of blood pressure before and after neurosurgical decompression in hypertensive patients with different types of neurovascular compression of brain stem. ( 24247558 )
2013
4
Elevated diffusion anisotropy in gray matter and the degree of brain compression. ( 22680241 )
2012
5
Determination of friction coefficient in unconfined compression of brain tissue. ( 23026694 )
2012
6
Brain compression without global neuronal loss in meningiomas: whole-brain proton MR spectroscopy report of 2 cases. ( 16219819 )
2005
7
Neonatal subgaleal hematoma causing brain compression: report of two cases and review of the literature. ( 12762894 )
2003
8
The effect of brain compression under venous circulatory impairment. ( 11091978 )
2000
9
Moderate hypothermia for 48 hours after temporary epidural brain compression injury in a canine outcome model. ( 9605347 )
1998
10
Progressive brain compression. Changes in vital physiological variables, correlated with brain tissue water content and brain tissue displacement. Experimental MR imaging in dogs. ( 8489844 )
1993
11
The effect of resuscitative moderate hypothermia following epidural brain compression on cerebral damage in a canine outcome model. ( 8331408 )
1993
12
Pathophysiology of brain swelling after acute experimental brain compression and decompression. ( 8437667 )
1993
13
Contribution of brain distortion and displacement to CSF dynamics in experimental brain compression. ( 1992818 )
1991
14
Rebound of ICP after brain compression. An MRI study in dogs. ( 2251941 )
1990
15
Brain tissue elastic behavior and experimental brain compression. ( 3189591 )
1988
16
Magnetic resonance imaging of brain tissue displacement and brain tissue water contents during progressive brain compression. An experimental study in dogs. ( 2980493 )
1986
17
Changes of frequency spectrum of the CSF pulse wave caused by supratentorial epidural brain compression. ( 3806113 )
1986
18
Brain elastic behavior in experimental brain compression: influence of steroid therapy. ( 6744052 )
1984
19
Effect of brain compression on pyramidal tract responses in the cat. ( 6788586 )
1981
20
The physiological basis of intracranial pressure change with progressive epidural brain compression. An experimental evaluation in cats. ( 903806 )
1977
21
Proceedings: The intracranial volume-pressure response during experimental brain compression in primates. ( 4208974 )
1974
22
Intracranial volume--pressure relationships during experimental brain compression in primates. 2. Effect of induced changes in systemic arterial pressure and cerebral blood flow. ( 4443804 )
1974
23
Intracranial volume--pressure relationships during experimental brain compression in primates. 3. Effect of mannitol and hyperventilation. ( 4443805 )
1974
24
Intracranial volume--pressure relationships during experimental brain compression in primates. 1. Pressure responses to changes in ventricular volume. ( 4443803 )
1974
25
Experimental epidural brain compression. ( 4469147 )
1974
26
EEG frequency spectra after the epidural brain compression in rabbits. ( 4698082 )
1973
27
Dimethyl sulfoxide in the treatment of experimental brain compression. ( 4197201 )
1973
28
Cerebral blood flow regulation during experimental brain compression. ( 4719697 )
1973
29
The effect of sublethal epidural brain compression on the EEG broadband frequency spectrum in the rabbit. (Preliminary communication). ( 5052824 )
1972
30
Hypothalamic-hypophysial adrenal and thyroid systems: observations in fetal rats subjected to hypothalamic destruction, brain compression and hypervitaminosis A. ( 5436115 )
1970
31
Regional cerebral blood flow (rCBF) changes following local brain compression in the cat. ( 5714629 )
1968
32
Experimental brain compression. Electroencephalographic consequences. ( 13789854 )
1961
33
Tentorial herniation, the mid brain and the pupil. Experimental studies in brain compression. ( 14407085 )
1960
34
Studies in experimental brain swelling and brain compression. ( 13834474 )
1959
35
Compression of brain arteries as pathogenetic factor for tissue necroses and their areas of predilection. ( 14392475 )
1955

Variations for Brain Compression

Expression for Brain Compression

Search GEO for disease gene expression data for Brain Compression.

Pathways for Brain Compression

Pathways related to Brain Compression according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.77 FGF2 PLAT
2 10.31 FGF2 PLAT

GO Terms for Brain Compression

Cellular components related to Brain Compression according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.62 AVP PLAT

Sources for Brain Compression

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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