Aliases & Classifications for Brain Injury

MalaCards integrated aliases for Brain Injury:

Name: Brain Injury 38 54

Classifications:



Summaries for Brain Injury

NINDS : 54 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

MalaCards based summary : Brain Injury is related to neonatal hypoxic and ischemic brain injury and head injury. An important gene associated with Brain Injury is ASIC1 (Acid Sensing Ion Channel Subunit 1), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Neuroscience. The drugs Zinc and Mannitol have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and bone, and related phenotypes are Decreased viability with paclitaxel and Decreased viability with paclitaxel

Related Diseases for Brain Injury

Diseases related to Brain Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 337)
# Related Disease Score Top Affiliating Genes
1 neonatal hypoxic and ischemic brain injury 34.3 BDNF ENO2 MBP
2 head injury 33.1 APOE ENO2 S100B
3 persistent vegetative state 32.8 APOE ENO2
4 periventricular leukomalacia 32.6 EPO IL6 MBP
5 spinal cord injury 30.4 BDNF CASP3 GFAP IL6
6 status epilepticus 30.3 BDNF CASP3 ENO2 GFAP
7 stroke, ischemic 29.9 APOE CASP3 ENO2 MBP
8 bacterial meningitis 29.8 IL10 IL6 S100B
9 alzheimer disease 29.8 APOE BDNF CASP3 GFAP MAPT S100B
10 post-traumatic stress disorder 29.7 BDNF COMT DRD2
11 akinetic mutism 29.6 ENO2 MAPT
12 sleep apnea 29.5 APOE IGF1 IL6 S100B
13 alexithymia 29.5 COMT DRD2 IL6
14 hydrocephalus 29.2 APOE ENO2 GFAP MAPT MBP
15 supranuclear palsy, progressive, 1 29.2 APOE DRD2 MAPT
16 psychotic disorder 29.1 BDNF COMT DRD2 S100B
17 paranoid schizophrenia 29.1 BDNF COMT S100B
18 personality disorder 29.0 BDNF COMT DRD2
19 substance abuse 28.7 BDNF COMT DRD2
20 mood disorder 28.3 BDNF COMT DRD2 IL6
21 multiple sclerosis 28.2 APOE BDNF GFAP IL10 IL6 MBP
22 major depressive disorder 28.0 APOE BDNF COMT DRD2 IL6
23 disease of mental health 27.5 APOE BDNF COMT DRD2 MAPT
24 traumatic brain injury 27.2 APOE BDNF CASP3 COMT DRD2 ENO2
25 bipolar disorder 27.0 BDNF COMT DRD2 IGF1 MAPT
26 moderate and severe traumatic brain injury 12.3
27 pseudobulbar affect 11.1
28 agnosia 11.1
29 locked-in syndrome 11.1
30 epilepsy 11.0
31 cerebral hypoxia 11.0
32 shaken baby syndrome 11.0
33 dysphagia 11.0
34 cerebral atrophy 11.0
35 post-traumatic epilepsy 11.0
36 apraxia 11.0
37 swallowing disorders 11.0
38 speech and communication disorders 11.0
39 dementia pugilistica 11.0
40 west syndrome 11.0
41 tremor 11.0
42 vibrio vulnificus infection 10.9 EPO IL6
43 bednar tumor 10.8 ENO2 S100B
44 prosopagnosia, hereditary 10.8
45 primitive neuroectodermal tumor of the cervix uteri 10.8 ENO2 GFAP
46 intracranial cysts 10.8 ENO2 GFAP S100B
47 melanotic neuroectodermal tumor 10.7 ENO2 GFAP S100B
48 pineocytoma 10.7 ENO2 GFAP S100B
49 papillary ependymoma 10.7 ENO2 GFAP S100B
50 subependymal giant cell astrocytoma 10.7 ENO2 GFAP S100B

Graphical network of the top 20 diseases related to Brain Injury:



Diseases related to Brain Injury

Symptoms & Phenotypes for Brain Injury

GenomeRNAi Phenotypes related to Brain Injury according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with paclitaxel GR00179-A-1 8.92 IGF1 IL10 CASP3
2 Decreased viability with paclitaxel GR00179-A-2 8.92 IGF1

MGI Mouse Phenotypes related to Brain Injury:

46 (show all 18)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.45 IL10 MAPT IL6 MBP S100B SLC24A2
2 homeostasis/metabolism MP:0005376 10.39 IL10 MAPT IL6 MBP S100B SLC24A2
3 cellular MP:0005384 10.37 IL10 MAPT MBP IL6 SPTAN1 APOE
4 cardiovascular system MP:0005385 10.35 IL10 MAPT IL6 SPTAN1 UCHL1 APOE
5 growth/size/body region MP:0005378 10.35 IL10 MAPT IL6 SPTAN1 UCHL1 MBP
6 nervous system MP:0003631 10.31 IL10 MAPT IL6 MBP SLC24A2 SPTAN1
7 mortality/aging MP:0010768 10.27 IL6 IL10 MAPT IGF1 MBP SPTAN1
8 hematopoietic system MP:0005397 10.26 IL6 IL10 MAPT IGF1 UCHL1 MBP
9 immune system MP:0005387 10.24 IGF1 IL6 IL10 MAPT MBP APOE
10 integument MP:0010771 10.22 IL10 MAPT IL6 S100B UCHL1 APOE
11 digestive/alimentary MP:0005381 10.15 IL6 IL10 UCHL1 APOE CASP3 BDNF
12 muscle MP:0005369 10.09 IL10 MAPT IL6 APOE CASP3 DRD2
13 normal MP:0002873 10.07 IL10 MAPT S100B SPTAN1 MBP BDNF
14 renal/urinary system MP:0005367 9.92 MAPT IGF1 IL6 UCHL1 APOE CASP3
15 reproductive system MP:0005389 9.91 IGF1 IL6 IL10 MBP BDNF APOE
16 respiratory system MP:0005388 9.9 IL10 IL6 UCHL1 APOE CASP3 BDNF
17 taste/olfaction MP:0005394 9.43 MAPT APOE CASP3 BDNF DRD2 ENO2
18 vision/eye MP:0005391 9.28 IL10 MAPT IL6 SLC24A2 MBP APOE

Drugs & Therapeutics for Brain Injury

Drugs for Brain Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 655)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc Approved, Investigational Phase 4,Phase 2 7440-66-6 23994
2
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 69-65-8 453 6251
3
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
4
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 57-27-2 5288826
5
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
6
Citalopram Approved Phase 4,Phase 2,Not Applicable 59729-33-8 2771
7
Amantadine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 768-94-5 2130
8
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
9
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
10
Ticlopidine Approved Phase 4 55142-85-3 5472
11
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
12
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 113775-47-6 68602 5311068
13
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2078-54-8 4943
14
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
15
Sevoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 28523-86-6 5206
16
Sufentanil Approved, Investigational Phase 4,Phase 2 56030-54-7 41693
17
Atracurium Approved, Experimental, Investigational Phase 4 64228-79-1 47319
18
Cisatracurium Approved Phase 4 96946-41-7
19
Aspirin Approved, Vet_approved Phase 4,Phase 2 50-78-2 2244
20
Levodopa Approved Phase 4,Phase 1,Phase 2 59-92-7 6047
21
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
22
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 99-66-1 3121
23
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
24
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
25
Memantine Approved, Investigational Phase 4,Phase 2,Not Applicable 19982-08-2 4054
26
Etomidate Approved Phase 4 33125-97-2 36339 667484
27
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 437-38-7 3345
28
Baclofen Approved Phase 4,Phase 3,Phase 2,Phase 1 1134-47-0 2284
29
Acetylcholine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 51-84-3 187
30
Methylphenidate Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 113-45-1 4158
31
Norepinephrine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 51-41-2 439260
32
Enoxaparin Approved Phase 4,Phase 1 9005-49-6 772
33
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 64-17-5 702
34
Acetaminophen Approved Phase 4,Phase 2,Not Applicable 103-90-2 1983
35
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-43-4 5816
36
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-23-7 5754
37
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 329-65-7 838
38
Ibuprofen Approved Phase 4,Phase 3,Phase 2,Not Applicable 15687-27-1 3672
39
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 1 525-66-6 4946
40
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
41
Exenatide Approved, Investigational Phase 4,Not Applicable 141758-74-9 15991534
42
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
43
Testosterone Approved, Investigational Phase 4,Phase 2,Not Applicable 58-22-0 6013
44
Testosterone enanthate Approved Phase 4,Phase 2 315-37-7 9416
45
Testosterone undecanoate Approved, Investigational Phase 4,Phase 2 5949-44-0
46
Dalteparin Approved Phase 4,Phase 2 9005-49-6
47
Heparin Approved, Investigational Phase 4,Phase 2,Not Applicable 9005-49-6 772 46507594
48
Fosphenytoin Approved, Investigational Phase 4,Not Applicable 93390-81-9 56339
49
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 57-41-0 1775
50 Piracetam Approved, Investigational Phase 4,Phase 3,Phase 2 7491-74-9

Interventional clinical trials:

(show top 50) (show all 2422)
# Name Status NCT ID Phase Drugs
1 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4 Ramelteon
2 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4 Insulin
3 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4 Cerebrolysin;0.9% NaCl, saline
4 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4 Midazolam;Placebo
5 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4 Diclofenac
6 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4 citalopram;Placebo
7 Growth Hormone and Brain Functioning After Traumatic Brain Injury Unknown status NCT01699308 Phase 4 Genotropin (somatropin)
8 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
9 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4 Amantadine hydrochloride;Placebo capsule
10 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4 Clopidogrel;Atorvastatin
11 The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery Unknown status NCT02123355 Phase 4 Induction of anesthesia;Sevoflurane, remifentanil ,vecuronium;Dexmedetomidine;Placebo
12 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
13 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4 discontinuation of aspirin therapy;continuation of aspirin therapy
14 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4 Insulin (Actrapid)
15 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4 L- DOPA;placebo
16 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4 Use of prophylactic anticonvulsants (valproate, clonazepam);Control group
17 TXA in the EMS on the Helicopter and the Ambulance Unknown status NCT02354885 Phase 4 Tranexamic Acid
18 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
19 Creative Therapy to Affect Stroke Outcomes Unknown status NCT01455155 Phase 4
20 Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial Unknown status NCT00196703 Phase 4 memantine
21 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
22 A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients Unknown status NCT02147678 Phase 4 Etomidate;Propofol;Remifentanil;Anesthesia induction
23 Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery Unknown status NCT02133638 Phase 4 Sevoflurane;Propofol
24 Consequence of Dexmedetomidine on Emergence Deliruim After Sevoflurane Anesthesia in Children With Cerebral Palsy Unknown status NCT02244515 Phase 4 dexmedetomidine
25 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Unknown status NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
26 The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy Unknown status NCT01256021 Phase 4 Botulinum Toxin Type A
27 Effects of Functional Electrical Stimulation on Gait in Children With Cerebral Palsy Unknown status NCT02462018 Phase 4
28 Using Propranolol in Traumatic Brain Injury to Reduce Sympathetic Storm Phenomenon Completed NCT03401515 Phase 4 Propranolol Hydrochloride 1 MG/ML
29 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4 Rivastigmine
30 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4 methylphenidate
31 Intravenous Exenatide in Patients With Acute Brain Injury Completed NCT02058940 Phase 4 Exenatide
32 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4 Venlafaxine
33 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4 Methylphenidate;Placebo
34 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
35 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4 Androgel (Testosterone Gel);Androgel Placebo
36 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4 Recombinant human growth hormone
37 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4 citalopram (celexa)
38 The Use of Low Molecular Weight Heparin in Traumatic Brain Injury Completed NCT00170378 Phase 4 Enoxaparin
39 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4 Dipeptiven
40 Effect of Erythropoietin on Preterm Brain Injury Completed NCT02036073 Phase 4 recombinant human erythropoietin
41 Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients Completed NCT03480880 Phase 4
42 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4 Levetiracetam;Phenytoin
43 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4 Topiramate;Placebo
44 Simvastatin for mTBI Completed NCT01952288 Phase 4 simvastatin;Placebo Oral Tablet
45 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4 Nuedexta (DM 20 mg/Q 10 mg)
46 Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity Completed NCT00178646 Phase 4 Botox
47 Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies Completed NCT01695070 Phase 4 Melatonin
48 BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity Completed NCT00430196 Phase 4 BOTOX®;Zanaflex®
49 Enteral Glutamine in Neurologically-injured Patients Completed NCT00204971 Phase 4
50 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate

Search NIH Clinical Center for Brain Injury

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Brain Injury cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Brain Injury:
Hematopoietic stem cells for treatment of ischemic brain injury
Embryonic/Adult Cultured Cells Related to Brain Injury:
Bone marrow-derived hematopoietic stem cells (family)

Genetic Tests for Brain Injury

Anatomical Context for Brain Injury

MalaCards organs/tissues related to Brain Injury:

41
Brain, Testes, Bone, Heart, Eye, Spinal Cord, Cortex

Publications for Brain Injury

Articles related to Brain Injury:

(show top 50) (show all 2178)
# Title Authors Year
1
Association of Histologic Chorioamnionitis With Perinatal Brain Injury and Early Childhood Neurodevelopmental Outcomes Among Preterm Neonates. ( 29610829 )
2018
2
Effects of pregabalin on brain edema, neurologic and histologic outcomes in experimental traumatic brain injury. ( 29730418 )
2018
3
Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. ( 29572821 )
2018
4
Brain injury and neural stem cells. ( 29451199 )
2018
5
Impaired autophagic flux is associated with the severity of trauma and the role of A<sub>2A</sub>R in brain cells after traumatic brain injury. ( 29449536 )
2018
6
Alpha desynchronization/synchronization during working memory testing is compromised in acute mild traumatic brain injury (mTBI). ( 29444081 )
2018
7
Intravenous saline administration in patients with severe acquired brain injury and orthostatic intolerance for tilt-table mobilization. ( 29190150 )
2018
8
OXIDIZED PHOSPHOLIPID SIGNALING IN TRAUMATIC BRAIN INJURY. ( 29964171 )
2018
9
Robotically-driven orthoses exert proximal-to-distal differential recovery on the lower limbs in children with hemiplegia, early after acquired brain injury. ( 29650492 )
2018
10
Phenol neurolysis for management of shoulder spasticity in early recovery from traumatic brain injury - a case report. ( 29933094 )
2018
11
Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization. ( 29448108 )
2018
12
Safety, Tolerability, and Effectiveness of Dextromethorphan/Quinidine for Pseudobulbar Affect Among Study Participants With Traumatic Brain Injury: Results From the PRISM-II Open Label Study. ( 29477412 )
2018
13
Epileptiform activity in traumatic brain injury predicts post-traumatic epilepsy. ( 29537656 )
2018
14
Intracranial pressure thresholds in severe traumatic brain injury: Con : The injured brain is not aware of ICP thresholds! ( 29978388 )
2018
15
Mild traumatic brain injury: evaluation of olfactory dysfunction and clinical-neurological characteristics. ( 29446651 )
2018
16
Corrigendum: Image of the month: Dysphagia due to injury of the corticobulbar tract following traumatic brain injury. ( 29436459 )
2018
17
Long-term and delayed functional recovery in patients with severe cerebrovascular and traumatic brain injury requiring tracheostomy. ( 29979120 )
2018
18
Comparing disability between traumatic brain injury and spinal cord injury using the 12-item WHODAS 2.0 and the WHO minimal generic data set covering functioning and health. ( 29962230 )
2018
19
Traumatic Brain Injury and Firearm Use and Risk of Progressive Supranuclear Palsy Among Veterans. ( 29973911 )
2018
20
Clinical predictive score of intracranial hemorrhage in mild traumatic brain injury. ( 29440905 )
2018
21
Towards a Clinical Neuroethics for Brain Injury Practice: An Introduction to a New Special Feature for Ethics in JHTR. ( 29975255 )
2018
22
The incidence of anosmia after traumatic brain injury: the SHEFBIT cohort. ( 29874472 )
2018
23
Susceptibility-weighted and diffusion kurtosis imaging to evaluate encephalomalacia with epilepsy after traumatic brain injury. ( 29761118 )
2018
24
Evidence- and Consensus-Based Guidelines for the Management of Communication and Swallowing Disorders Following Pediatric Traumatic Brain Injury. ( 29385009 )
2018
25
The development of a new computer-adaptive test to evaluate strain in caregivers of individuals with traumatic brain injury: TBI-CareQOL Caregiver Strain. ( 29966647 )
2018
26
Risk of Traumatic Brain Injury Among Children, Adolescents, and Young Adults With Attention-Deficit Hyperactivity Disorder in Taiwan. ( 29970331 )
2018
27
Intracranial pressure thresholds in severe traumatic brain injury: Pro. ( 29978389 )
2018
28
Roles of elevated 20a89HETE in the breakdown of blood brain barrier and the severity of brain edema in experimental traumatic brain injury. ( 29568904 )
2018
29
Understanding health-related quality of life in caregivers of civilians and service members/veterans with traumatic brain injury: Reliability and validity data for the TBI-CareQOL measurement system. ( 29966648 )
2018
30
Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa I^-related pathway in rats. ( 29928110 )
2018
31
Obesity and Overweight Problems Among Individuals 1 to 25 Years Following Acute Rehabilitation for Traumatic Brain Injury: A NIDILRR Traumatic Brain Injury Model Systems Study. ( 29975254 )
2018
32
Alpha-Linolenic Acid Treatment Reduces the Contusion and Prevents the Development of Anxiety-Like Behavior Induced by a Mild Traumatic Brain Injury in Rats. ( 28844093 )
2018
33
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia. ( 29551690 )
2018
34
Management of traumatic brain injury patients. ( 29441170 )
2018
35
A CONCOMITANT BONE FRACTURE DELAYS COGNITIVE RECOVERY FROM TRAUMATIC BRAIN INJURY. ( 29787539 )
2018
36
Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice. ( 29439712 )
2018
37
Chronic Hypopituitarism Associated with Increased Postconcussive Symptoms Is Prevalent after Blast-Induced Mild Traumatic Brain Injury. ( 29515515 )
2018
38
Brain Oxygenation with a Non-vasoactive Perfluorocarbon Emulsion in a Rat Model of Traumatic Brain Injury. ( 29356218 )
2018
39
Hypertonic Saline Alleviates Brain Edema After Traumatic Brain Injury via Downregulation of Aquaporin 4 in Rats. ( 29600800 )
2018
40
Biomechanical simulation of traumatic brain injury in the rat. ( 29449041 )
2018
41
Efficacy and Harms of Pharmacological Interventions for Neurobehavioral Symptoms in Post Traumatic Amnesia after Traumatic Brain Injury - A Systematic Review. ( 29969935 )
2018
42
A Comparative Study of Two Blast-Induced Traumatic Brain Injury Models: Changes in Monoamine and Galanin Systems Following Single and Repeated Exposure. ( 29973912 )
2018
43
Diffusion Tensor Imaging (DTI) Correlates of Self-Reported Sleep Quality and Depression Following Mild Traumatic Brain Injury. ( 29973910 )
2018
44
Temporal Lobe Epilepsy, Stroke, and Traumatic Brain Injury: Mechanisms of Hyperpolarized, Depolarized, and Flow-Through Ion Channels Utilized as Tri-Coordinate Biomarkers of Electrophysiologic Dysfunction. ( 29951646 )
2018
45
Histopathological and Behavioral Assessments of Aging Effects on Stem Cell Transplants in an Experimental Traumatic Brain Injury. ( 29445958 )
2018
46
From Mechanical to Chemical: A Case of Diabetes Insipidus Induced by Concussive Brain Injury. ( 29596786 )
2018
47
Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury. ( 29695462 )
2018
48
Extended Erythropoietin Treatment Prevents Chronic Executive Functional and Microstructural Deficits Following Early Severe Traumatic Brain Injury in Rats. ( 29971038 )
2018
49
The Interactive Effect of Traumatic Brain Injury and Psychiatric Symptoms on Cognition Among Late Middle-Aged Men: Findings from the Vietnam Era Twin Study of Aging (VETSA). ( 29978738 )
2018
50
Mild Traumatic Brain Injury Associated with Internal Carotid Artery Dissection and Pseudoaneurysm. ( 29937650 )
2018

Variations for Brain Injury

Expression for Brain Injury

Search GEO for disease gene expression data for Brain Injury.

Pathways for Brain Injury

GO Terms for Brain Injury

Cellular components related to Brain Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.81 APOE BDNF ENO1 ENO2 EPO IGF1
2 dendrite GO:0030425 9.8 APOE BDNF COMT DRD2 MAPT
3 axon GO:0030424 9.77 BDNF COMT DRD2 MAPT UCHL1
4 myelin sheath GO:0043209 9.62 ENO2 GFAP MBP UCHL1
5 phosphopyruvate hydratase complex GO:0000015 9.26 ENO1 ENO2
6 cell body GO:0044297 9.26 COMT EPO GFAP MAPT
7 neuronal cell body GO:0043025 9.1 APOE ENO2 MAPT MBP S100B UCHL1
8 extracellular region GO:0005576 10.09 APOE BDNF EPO IGF1 IL10 IL6

Biological processes related to Brain Injury according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.67 CASP3 COMT EPO IL10
2 regulation of signaling receptor activity GO:0010469 9.63 BDNF EPO IGF1 IL10 IL6 MAPT
3 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.61 EPO IGF1 IL6
4 long-term synaptic potentiation GO:0060291 9.5 GFAP S100B SLC24A2
5 axon development GO:0061564 9.49 GFAP MAPT
6 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.48 IL10 MBP
7 axonal transport of mitochondrion GO:0019896 9.46 MAPT UCHL1
8 neuron projection regeneration GO:0031102 9.4 APOE GFAP
9 response to inactivity GO:0014854 9.26 DRD2 IL10
10 response to glucocorticoid GO:0051384 9.26 CASP3 IL10 IL6 S100B
11 memory GO:0007613 9.02 ASIC1 BDNF MAPT S100B SLC24A2

Molecular functions related to Brain Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 BDNF IGF1 IL10 IL6
2 lipoprotein particle binding GO:0071813 9.16 APOE MAPT
3 phosphopyruvate hydratase activity GO:0004634 8.62 ENO1 ENO2

Sources for Brain Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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