MCID: BRN080
MIFTS: 44

Brain Ischemia

Categories: Neuronal diseases

Aliases & Classifications for Brain Ischemia

MalaCards integrated aliases for Brain Ischemia:

Name: Brain Ischemia 38 55 73

Classifications:



External Ids:

UMLS 73 C0007786

Summaries for Brain Ischemia

MalaCards based summary : Brain Ischemia is related to ischemia and central nervous system teratoma. An important gene associated with Brain Ischemia is KCNB1 (Potassium Voltage-Gated Channel Subfamily B Member 1), and among its related pathways/superpathways are Circadian entrainment and Melatonin metabolism and effects. The drugs Aspirin and Cilostazol have been mentioned in the context of this disorder. Affiliated tissues include Brain and Brain.

Wikipedia : 76 Brain ischemia (a.k.a. cerebral ischemia, cerebrovascular ischemia) is a condition in which there is... more...

Related Diseases for Brain Ischemia

Diseases related to Brain Ischemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 ischemia 29.2 ADORA1 EDN1 GFAP MAP2 NOS2
2 central nervous system teratoma 10.6 GFAP NES
3 anaplastic ganglioglioma 10.6 GFAP NES
4 central nervous system germ cell tumor 10.6 GFAP NES
5 central nervous system primitive neuroectodermal neoplasm 10.6 GFAP NES
6 ependymoblastoma 10.6 GFAP NES
7 astroblastoma 10.6 GFAP NES
8 medulloepithelioma 10.5 GFAP NES
9 subependymoma 10.5 GFAP NES
10 tanycytic ependymoma 10.5 GFAP NES
11 papillary ependymoma 10.5 GFAP NES
12 gliomatosis cerebri 10.5 GFAP NES
13 neuronitis 10.5
14 subependymal giant cell astrocytoma 10.5 GFAP NES
15 retinitis pigmentosa 42 10.4 GFAP NES
16 chiari malformation 10.4 GFAP MAP2
17 infratentorial cancer 10.4 GFAP NES
18 hemimegalencephaly 10.3 GFAP MAP2
19 pleomorphic xanthoastrocytoma 10.3 GFAP MAP2
20 mucopolysaccharidosis, type iiia 10.3 MAP2 NES
21 neurilemmoma 10.3 GFAP NES
22 cerebritis 10.3
23 cerebellar liponeurocytoma 10.3 GFAP MAP2
24 clear cell ependymoma 10.2 GFAP MAP2
25 optic nerve neoplasm 10.2 MAP2 NES
26 ependymoma 10.1 GFAP NES
27 scrapie 10.1 GFAP MAP2
28 sleeping sickness 10.1 HSPA8 NOS2
29 hypoxia 10.1
30 aging 10.0
31 brain injury 10.0
32 hepatopulmonary syndrome 10.0 EDN1 NOS2
33 dysembryoplastic neuroepithelial tumor 10.0 GFAP MAP2 NES
34 central neurocytoma 10.0 GFAP MAP2 NES
35 brain glioma 10.0 GFAP MAP2 NES
36 optic nerve glioma 10.0 GFAP MAP2 NES
37 ganglioglioma 10.0 GFAP MAP2 NES
38 spinal cord injury 9.9 GFAP NOS2
39 alzheimer disease 9.9
40 cardiac arrest 9.9
41 cerebral artery occlusion 9.9
42 hyperglycemia 9.8
43 endotheliitis 9.8
44 arteries, anomalies of 9.7
45 traumatic brain injury 9.7
46 protein-energy malnutrition 9.7
47 carotid stenosis 9.7
48 dementia 9.7
49 angioedema 9.7
50 transient cerebral ischemia 9.7

Graphical network of the top 20 diseases related to Brain Ischemia:



Diseases related to Brain Ischemia

Symptoms & Phenotypes for Brain Ischemia

Drugs & Therapeutics for Brain Ischemia

Drugs for Brain Ischemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 457)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 50-78-2 2244
2
Cilostazol Approved, Investigational Phase 4,Phase 3 73963-72-1 2754
3
Probucol Approved, Investigational Phase 4 23288-49-5 4912
4
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
5
Levodopa Approved Phase 4 59-92-7 6047
6
Ephedrine Approved Phase 4,Phase 2,Not Applicable 299-42-3 9294
7
Oxymetazoline Approved, Investigational Phase 4,Phase 2 1491-59-4 4636
8
Phenylephrine Approved Phase 4,Phase 2 59-42-7 6041
9
Pseudoephedrine Approved Phase 4,Phase 2,Not Applicable 90-82-4 7028
10
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 120202-66-6, 113665-84-2 60606
11
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 55142-85-3 5472
12
Angiotensin II Approved, Investigational Phase 4,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
13
Atenolol Approved Phase 4 29122-68-7 2249
14
Valsartan Approved, Investigational Phase 4,Not Applicable 137862-53-4 60846
15
Heparin Approved, Investigational Phase 4,Phase 3 9005-49-6 772 46507594
16 Nadroparin Approved, Investigational Phase 4 9041-08-1
17
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 1994-09-7, 94-09-7 2337
18
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 7440-66-6 23994
19
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 7487-88-9 24083
20
Dalteparin Approved Phase 4,Phase 3,Phase 2 9005-49-6
21
Warfarin Approved Phase 4,Phase 2,Phase 3 81-81-2 6691 54678486
22
Apixaban Approved Phase 4,Phase 3,Not Applicable 503612-47-3 10182969
23 Edoxaban Approved Phase 4,Phase 2,Phase 3,Not Applicable 480449-70-5
24
Rivaroxaban Approved Phase 4,Phase 2,Not Applicable 366789-02-8
25 Piracetam Approved, Investigational Phase 4,Phase 2 7491-74-9
26
Dipyridamole Approved Phase 4,Not Applicable 58-32-2 3108
27
Nimodipine Approved, Investigational Phase 4,Not Applicable 66085-59-4 4497
28
Triflusal Approved, Investigational Phase 4 322-79-2
29
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 51-43-4 5816
30
Racepinephrine Approved Phase 4,Phase 2,Phase 3,Not Applicable 329-65-7 838
31
Amlodipine Approved Phase 4,Phase 2,Not Applicable 88150-42-9 2162
32
Losartan Approved Phase 4 114798-26-4 3961
33
Antipyrine Approved, Investigational Phase 4,Phase 3,Phase 2 60-80-0 2206
34
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
35
Enoxaparin Approved Phase 4,Phase 3 9005-49-6 772
36
Tranexamic Acid Approved Phase 4 1197-18-8 5526
37
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
38
Simvastatin Approved Phase 4,Phase 3,Phase 2,Not Applicable 79902-63-9 54454
39
Allopurinol Approved Phase 4,Phase 3 315-30-0 2094
40
Fluvastatin Approved Phase 4 93957-54-1 1548972
41
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
42
Abciximab Approved Phase 4,Phase 3 143653-53-6
43 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable
44
Serine Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable 56-45-1 5951
45
Tocopherol Approved, Investigational, Nutraceutical Phase 4,Phase 2,Phase 1 1406-66-2 14986
46
Vitamin C Approved, Nutraceutical Phase 4,Phase 2,Not Applicable 50-81-7 5785 54670067
47
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 1 59-02-9 14985
48
Choline Approved, Nutraceutical Phase 4,Phase 3 62-49-7 305
49 Ozagrel Investigational Phase 4 82571-53-7
50 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 892)
# Name Status NCT ID Phase Drugs
1 PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study Unknown status NCT02483169 Phase 4 cilostazol;Probucol;Aspirin;placebo of cilostazol;Placebo of aspirin
2 PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage Unknown status NCT01013532 Phase 4 Cilostazol;Probucol;Aspirin;placebo of cilostazol;placebo of aspirin
3 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
4 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4 L- DOPA;placebo
5 Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery Unknown status NCT01794273 Phase 4 ephedrine and phenylephrine
6 The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion Unknown status NCT02594995 Phase 4 NBP
7 The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized and Cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral Infarction Unknown status NCT02411903 Phase 4 atorvastatin and clopidogrel;rosuvastatin and clopidogrel
8 Clopidogrel for Acute Ischaemia of Recent Onset Unknown status NCT02776540 Phase 4 Clopidogrel;Aspirin
9 The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels Unknown status NCT01926834 Phase 4 Erigeron Injection;placebo
10 Comprehensive Reparative Therapy in Ischemic Stroke COMplex Repair in Ischemic Stroke-Arm Unknown status NCT02581371 Phase 4 Cerebrolysin infusion
11 Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol Unknown status NCT02403349 Phase 4 Fimasartan;Valsartan;Atenolol
12 Safety and Efficacy of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke Unknown status NCT01862978 Phase 4 Heparin;Nadroparin;Placebo
13 Efficacy Study of Huatuo Zaizao Pills in Improving of Neural Function in Acute Ischemic Stroke Unknown status NCT01758536 Phase 4 Huatuo Zaizao Pills
14 Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy Unknown status NCT01097967 Phase 4
15 Valsartan Efficacy on Modest Blood Pressure Reduction in Acute Ischemic Stroke Unknown status NCT00874601 Phase 4 Diovan® (valsartan)
16 Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke Unknown status NCT00747279 Phase 4 Intensive insulin therapy
17 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4 Butylphthalide Soft Capsules;Aspirin
18 Single High Dose Vitamin C, E in Severe Birth Asphyxia Completed NCT01743742 Phase 4 Vitamin E, Vitamin C
19 ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial Completed NCT00161070 Phase 4 anticoagulation;aspirin and dipyridamole;aspirin alone
20 Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth Completed NCT00120588 Phase 4 magnesium
21 Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke (Japan Alteplase Clinical Trial Ⅱ:J-ACT Ⅱ) Completed NCT00412867 Phase 4 Alteplase
22 The Effect of Cilostazol Compared to Aspirin on Endothelial Function in Acute Cerebral Ischemia Patients Completed NCT03116269 Phase 4 Cilostazol 100mg;Aspirin
23 The Effect of Ventilation on Cerebral Oxygenation in the Sitting Position Completed NCT01546636 Phase 4
24 Clopidogrel Response and CYP2C19 Genotype in Ischemic Stroke Patients Completed NCT03385538 Phase 4 Clopidogrel
25 Nimodipine for Treating Acute Massive Cerebral Infarction Completed NCT02248233 Phase 4 Nimodipine;Saline + citicoline
26 AdminiStration of Statin On Acute Ischemic stRoke patienT Trial Completed NCT02549846 Phase 4 Statin
27 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4 Atorvastatin
28 A Safety Study of Ginkgolides Meglumine Injection in the Treatment of Ischemic Stroke. Completed NCT01958957 Phase 4 Ginkgolides Meglumine Injection
29 Tongxinluo Capsule in Ischemic Stroke Patients(TISS) Completed NCT01919671 Phase 4 Tongxinluo capsule;placebo capsule
30 Comparison of Triflusal and Clopidogrel in Secondary Prevention of Stroke Based on the Genotyping Completed NCT01174693 Phase 4 Triflusal;Clopidogrel
31 Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke Completed NCT01762163 Phase 4 Qizhitongluo Capsule;Naoxintong Capsule;Aspirin Enteric-coated Tablets;placebo
32 Effect of Cilostazol in the Acute Lacunar Infarction Based on Pulsatility Index of Transcranial Doppler Completed NCT00741286 Phase 4 Aspirin;cilostazol
33 The Safety and Efficacy of Cilostazol in Ischemic Stroke Patients With Peripheral Arterial Disease (SPAD Study) Completed NCT01188824 Phase 4 Cilostazol
34 Austrian Polyintervention Study to Prevent Cognitive Decline After Ischemic Stroke Completed NCT01109836 Phase 4
35 Thrombectomy REvascularization of Large Vessel Occlusions in Acute Ischemic Stroke (TREVO) Completed NCT01088672 Phase 4
36 Overcome Biochemical Aspirin Resistance Through Cilostazol Combination Completed NCT00446641 Phase 4 Cilostazol;placebo
37 Establishment and Evaluation to the Effects of a Clinical Pathway for Acute Ischemic Stroke Completed NCT00966316 Phase 4 aspirin,chinese herbs;
38 Preventing Recurrent Vascular Events in Patients With Stroke or Transient Ischemic Attack Completed NCT00931788 Phase 4 Antihypertensive agents and lipid lowering therapy
39 Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke Completed NCT00924638 Phase 4
40 Safety and Efficacy of Clopidogrel for Cerebral Infarction Treatment Completed NCT00386191 Phase 4 clopidogrel (SR25990C)
41 The Safety and Efficacy of Cerebrolysin in Patients With Acute Ischemic Stroke Completed NCT00868283 Phase 4 Cerebrolysin;0.9% Saline Solution
42 AISTCM-Outcome Measurement of Acute Ischemic Stroke With Traditional Chinese Medicine Completed NCT00351806 Phase 4 Erigeron breviscapus injection;hua tuo zai zao wan (a herbal medicine pill);Compound stroke herbal medicine (8 herbal)
43 Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject Completed NCT00823875 Phase 4 Cilostazol group;Probucol group;Cilostazol + Probucol group;control group
44 Platelet Hyperreactivity to Aspirin and Stroke Completed NCT00766896 Phase 4 Aspirin (platelet sensitive versus platelet hyperreactivity)
45 The Effect of Losartan Versus Amlodipine-based Therapy in Ischemic Stroke (0954-338)(COMPLETED) Completed NCT00754429 Phase 4 losartan;amlodipine
46 Cilostazol in Acute Ischemic Stroke Treatment (CAIST) Completed NCT00272454 Phase 4 Cilostazol;Aspirin
47 Post-marketing Study of Cilostazol (Cilostazol Stroke Prevention Study 2) Completed NCT00234065 Phase 4 Cilostazol;Aspirin
48 Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stroke Completed NCT00200356 Phase 4 Edaravone;Sodium Ozagrel
49 Quality Improvement in Stroke Prevention (QUISP) Completed NCT00328640 Phase 4 Optimal treatment
50 Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II Completed NCT00130039 Phase 4 clopidogrel;Cilostazol

Search NIH Clinical Center for Brain Ischemia

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Brain Ischemia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Brain Ischemia:
Mesenchymal stem cell-derived neuronal progenitor cells for the treatment of ischemic brain damage
Embryonic/Adult Cultured Cells Related to Brain Ischemia:
Neural progenitor cells PMIDs: 21300404

Genetic Tests for Brain Ischemia

Anatomical Context for Brain Ischemia

MalaCards organs/tissues related to Brain Ischemia:

41
Brain, Bone, Bone Marrow, Endothelial, Heart, Testes, Cortex
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Brain Ischemia:
# Tissue Anatomical CompartmentCell Relevance
1 Brain Forebrain White Matter Fibrous Astrocyte Cells Potential therapeutic candidate
2 Brain Neocortex Protoplasmic Astrocyte Cells Potential therapeutic candidate

Publications for Brain Ischemia

Articles related to Brain Ischemia:

(show top 50) (show all 673)
# Title Authors Year
1
Mechanism of Tau Hyperphosphorylation Involving Lysosomal Enzyme Asparagine Endopeptidase in a Mouse Model of Brain Ischemia. ( 29689717 )
2018
2
Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions. ( 29452136 )
2018
3
Critical Role of Flavin and Glutathione in Complex I-Mediated Bioenergetic Failure in Brain Ischemia/Reperfusion Injury. ( 29643256 )
2018
4
The protective effect of alpha-lipoic acid against brain ischemia and reperfusion injury via mTOR signaling pathway in rats. ( 29432779 )
2018
5
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia. ( 29551690 )
2018
6
Multidetector CT angiography of the Circle of Willis: association of its variants with carotid artery disease and brain ischemia. ( 29922933 )
2018
7
HMG-CoA Reductase Inhibitors Relieve Endoplasmic Reticulum Stress by Autophagy Inhibition in Rats With Permanent Brain Ischemia. ( 29970982 )
2018
8
Role of mTORC1 Controlling Proteostasis after Brain Ischemia. ( 29497356 )
2018
9
Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury. ( 29695462 )
2018
10
SUMOylation in brain ischemia: Patterns, targets, and translational implications. ( 29148315 )
2018
11
Reactive Oxygen Species Play a Biphasic Role in Brain Ischemia. ( 29420085 )
2018
12
Publisher Correction: Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury. ( 29695825 )
2018
13
Activation of JAK/STAT3 restores NK-cell function and improves immune defense after brain ischemia. ( 29401578 )
2018
14
Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia. ( 29315561 )
2018
15
Therapeutic Potential of Pretreatment with Allograft Sertoli Cells Transplantation in Brain Ischemia by Improving Oxidative Defenses. ( 29550901 )
2018
16
Bioinformatics analysis of microarray data to reveal the pathogenesis of brain ischemia. ( 29749511 )
2018
17
A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance. ( 29437797 )
2018
18
Flavonoids and its neuroprotective effects on brain ischemia and neurodegenerative diseases. ( 29577854 )
2018
19
Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways. ( 29912902 )
2018
20
Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury. ( 29472564 )
2018
21
Glutamate dehydrogenase as a neuroprotective target against brain ischemia and reperfusion. ( 27845178 )
2017
22
Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution. ( 28390980 )
2017
23
Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage. ( 29248829 )
2017
24
Microglia and macrophages differ in their inflammatory profile after permanent brain ischemia. ( 28843543 )
2017
25
LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice. ( 28880879 )
2017
26
Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons. ( 28626056 )
2017
27
Curcumin reverses neurochemical, histological and immuno-histochemical alterations in the model of global brain ischemia. ( 28053883 )
2017
28
Combined l-citrulline and glutathione administration prevents neuronal cell death following transient brain ischemia. ( 28315310 )
2017
29
Shifting Perceptions of Risk and Reward: Use of Anticoagulation in Patients With Acute Brain Ischemia and Atrial Fibrillation: Nine-Year Data From a National Acute Stroke Registry (National Acute Stroke Israeli Survey [NASIS]). ( 28258255 )
2017
30
Nontraditional Lipid Variables Predict Recurrent Brain Ischemia in Embolic Stroke of Undetermined Source. ( 28412318 )
2017
31
A new threshold of apparent diffusion coefficient values in white matter after successful tissue plasminogen activator treatment for acute brain ischemia. ( 28187865 )
2017
32
Sigma-1 receptor in brain ischemia/reperfusion: Possible role in the NR2A-induced pathway to regulate brain-derived neurotrophic factor. ( 28431607 )
2017
33
Transplantation of feeder-free human induced pluripotent stem cell-derived cortical neuron progenitors in adult male Wistar rats with focal brain ischemia. ( 29110329 )
2017
34
Brain ischemia: CT and MRI techniques in acute ischemic stroke. ( 29054448 )
2017
35
The effects of Y-27632 on pial microvessels during global brain ischemia and reperfusion in rabbits. ( 28270098 )
2017
36
Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury. ( 28914132 )
2017
37
Aromatase and neuroinflammation in rat focal brain ischemia. ( 28964927 )
2017
38
Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. ( 29138397 )
2017
39
Condition-specific transcriptional regulation of neuronal ion channel genes in brain ischemia. ( 29348796 )
2017
40
Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry. ( 27888142 )
2017
41
Radiographic and symptomatic brain ischemia in CEA and CAS: A systematic review and meta-analysis. ( 29021357 )
2017
42
Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation. ( 28360842 )
2017
43
Microglia-mediated BAFF-BAFFR ligation promotes neuronal survival in brain ischemia injury. ( 28918255 )
2017
44
The Protein Modification and Degradation Pathways after Brain Ischemia. ( 28967038 )
2017
45
G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway. ( 28823591 )
2017
46
Longitudinal Assessments of Normal and Perilesional Tissues in Focal Brain Ischemia and Partial Optic Nerve Injury with Manganese-enhanced MRI. ( 28230106 )
2017
47
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. ( 29058596 )
2017
48
Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway. ( 28642575 )
2017
49
Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations. ( 28314594 )
2017
50
G5G2.5 core-shell tecto-dendrimer specifically targets reactive glia in brain ischemia. ( 29280499 )
2017

Variations for Brain Ischemia

Expression for Brain Ischemia

Search GEO for disease gene expression data for Brain Ischemia.

Pathways for Brain Ischemia

GO Terms for Brain Ischemia

Cellular components related to Brain Ischemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 9.26 GFAP NES
2 basal part of cell GO:0045178 9.16 ADCY10 EDN1
3 cell body GO:0044297 9.13 ADORA1 GFAP MAP2
4 dendrite GO:0030425 9.02 ADCY10 ADORA1 HSPA8 KCNB1 MAP2

Biological processes related to Brain Ischemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway GO:0007193 9.43 ADORA1 EDN1
2 response to hypoxia GO:0001666 9.43 ADORA1 EDN1 NOS2
3 negative regulation of blood pressure GO:0045776 9.4 ADORA1 NOS2
4 regulation of sensory perception of pain GO:0051930 9.37 ADORA1 EDN1
5 positive regulation of cardiac muscle hypertrophy GO:0010613 9.32 EDN1 PARP1
6 regulation of protein complex assembly GO:0043254 9.16 GFAP HSPA8
7 regulation of cellular protein localization GO:1903827 8.96 MAP2 PARP1
8 negative regulation of hormone secretion GO:0046888 8.62 ADORA1 EDN1

Molecular functions related to Brain Ischemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.8 GFAP MAP2 NES

Sources for Brain Ischemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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