MCID: BRN011
MIFTS: 20

Brain Stem Astrocytic Neoplasm

Categories: Bone diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Brain Stem Astrocytic Neoplasm

MalaCards integrated aliases for Brain Stem Astrocytic Neoplasm:

Name: Brain Stem Astrocytic Neoplasm 12 15
Astrocytoma of Brain Stem 70
Brainstem Astrocytoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4860
NCIt 50 C7445
SNOMED-CT 67 107581000119103
UMLS 70 C1332608

Summaries for Brain Stem Astrocytic Neoplasm

Disease Ontology : 12 A brain stem glioma that is characterized by mass lesion of the brainstem, associated cranial nerve nuclei and long tracts, has material basis in abnormally proliferating cells derives from astrocytes.

MalaCards based summary : Brain Stem Astrocytic Neoplasm, also known as astrocytoma of brain stem, is related to adult brainstem astrocytoma and childhood brainstem astrocytoma. An important gene associated with Brain Stem Astrocytic Neoplasm is SNORD116@ (Small Nucleolar RNA, C/D Box 116 Cluster), and among its related pathways/superpathways are Autophagy Pathway and Hematopoietic cell lineage. Affiliated tissues include brain.

Related Diseases for Brain Stem Astrocytic Neoplasm

Diseases related to Brain Stem Astrocytic Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adult brainstem astrocytoma 11.1
2 childhood brainstem astrocytoma 11.1
3 glioma susceptibility 1 10.3
4 malignant astrocytoma 10.3
5 anaplastic astrocytoma 9.9
6 dysphagia 9.9

Graphical network of the top 20 diseases related to Brain Stem Astrocytic Neoplasm:



Diseases related to Brain Stem Astrocytic Neoplasm

Symptoms & Phenotypes for Brain Stem Astrocytic Neoplasm

Drugs & Therapeutics for Brain Stem Astrocytic Neoplasm

Search Clinical Trials , NIH Clinical Center for Brain Stem Astrocytic Neoplasm

Genetic Tests for Brain Stem Astrocytic Neoplasm

Anatomical Context for Brain Stem Astrocytic Neoplasm

MalaCards organs/tissues related to Brain Stem Astrocytic Neoplasm:

40
Brain

Publications for Brain Stem Astrocytic Neoplasm

Articles related to Brain Stem Astrocytic Neoplasm:

(show all 19)
# Title Authors PMID Year
1
Noncoding RNAs as potential biomarkers for DIPG diagnosis and prognosis: XIST and XIST-210 involvement. 61
32661825 2021
2
Radial Forearm Free Flap for Cochlear Implant Coverage in a Post-Irradiated Field. 61
31923157 2020
3
Brainstem astrocytoma as a neuro-Behçet's disease mimic. 61
30567204 2018
4
Child Neurology: Diencephalic syndrome-like presentation of a cervicomedullary brainstem tumor. 61
27872228 2016
5
Prognostic factors and survival in primary adult high grade brainstem astrocytoma: a population based study from 1973-2008. 61
24674698 2014
6
Treatment Outcomes and Prognostic Factors in Pediatric Non-brainstem Astrocytoma in North East of Iran. 61
25250156 2014
7
Long-term quality of life in children treated for posterior fossa brain tumors. 61
23829377 2013
8
p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas. 61
19240607 2009
9
Gaze-evoked nystagmus: a case report and literature review. 61
17765857 2007
10
Postoperative brain stem tension pneumocephalus causing transient locked-in syndrome. 61
17786010 2007
11
Intrinsic brainstem epidermoid cyst. Case report and review of the literature. 61
16619643 2006
12
Superior oblique paresis with contralateral relative afferent pupillary defect. 61
11148818 2000
13
Alveolar hypoventilation syndrome in brainstem glioma with improvement after surgical resection. 61
10893395 2000
14
Chronic arterial hypertension as unique symptom of brainstem astrocytoma. 61
7791459 1995
15
Surgical removal of brainstem astrocytomas and hemangioblastomas: report of three cases and review. 61
8516748 1993
16
Extraneural metastases from brainstem astrocytoma through ventriculoperitoneal shunt. 61
2030363 1991
17
Extraneural metastasis of a brainstem astrocytoma in a child: clinicopathological report. 61
3203482 1988
18
Magnetic resonance imaging of fibrillary brainstem astrocytoma. 61
3372469 1988
19
Central neurogenic hyperventilation in an awake patient with brainstem astrocytoma. 61
6810746 1982

Variations for Brain Stem Astrocytic Neoplasm

Expression for Brain Stem Astrocytic Neoplasm

Search GEO for disease gene expression data for Brain Stem Astrocytic Neoplasm.

Pathways for Brain Stem Astrocytic Neoplasm

Pathways related to Brain Stem Astrocytic Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.24 EPHB4 CSF3R
2 10.62 CSF3R CSF2RA

GO Terms for Brain Stem Astrocytic Neoplasm

Cellular components related to Brain Stem Astrocytic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor complex GO:0043235 8.8 EPHB4 CSF3R CSF2RA

Biological processes related to Brain Stem Astrocytic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 8.62 TWF1 EPHB4

Molecular functions related to Brain Stem Astrocytic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.16 TWF1 EPHB4
2 cytokine receptor activity GO:0004896 8.96 CSF3R CSF2RA
3 cytokine binding GO:0019955 8.62 CSF3R CSF2RA

Sources for Brain Stem Astrocytic Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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