MCID: BRN011
MIFTS: 23

Brain Stem Astrocytic Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Brain Stem Astrocytic Neoplasm

MalaCards integrated aliases for Brain Stem Astrocytic Neoplasm:

Name: Brain Stem Astrocytic Neoplasm 12 15
Astrocytoma of Brain Stem 73
Brainstem Astrocytoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4860
NCIt 50 C7445
UMLS 73 C1332608

Summaries for Brain Stem Astrocytic Neoplasm

Disease Ontology : 12 A brain stem glioma that is characterized by mass lesion of the brainstem, associated cranial nerve nuclei and long tracts, has material basis in abnormally proliferating cells derives from astrocytes.

MalaCards based summary : Brain Stem Astrocytic Neoplasm, also known as astrocytoma of brain stem, is related to adult brainstem astrocytoma and childhood brainstem astrocytoma. An important gene associated with Brain Stem Astrocytic Neoplasm is MARK3 (Microtubule Affinity Regulating Kinase 3). Affiliated tissues include brain, bone and spinal cord, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Brain Stem Astrocytic Neoplasm

Diseases related to Brain Stem Astrocytic Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adult brainstem astrocytoma 12.2
2 childhood brainstem astrocytoma 12.2
3 astrocytoma 10.0

Symptoms & Phenotypes for Brain Stem Astrocytic Neoplasm

GenomeRNAi Phenotypes related to Brain Stem Astrocytic Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.58 MARK3
2 Decreased viability GR00221-A-1 9.58 CDKN2A MARK3
3 Decreased viability GR00221-A-2 9.58 MARK3
4 Decreased viability GR00221-A-3 9.58 CDKN2A
5 Decreased viability GR00221-A-4 9.58 CDKN2A MARK3
6 Decreased viability GR00402-S-2 9.58 CDKN2A MARK3

MGI Mouse Phenotypes related to Brain Stem Astrocytic Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 8.96 CDKN2A MARK3
2 no phenotypic analysis MP:0003012 8.62 CDKN2A MARK3

Drugs & Therapeutics for Brain Stem Astrocytic Neoplasm

Search Clinical Trials , NIH Clinical Center for Brain Stem Astrocytic Neoplasm

Genetic Tests for Brain Stem Astrocytic Neoplasm

Anatomical Context for Brain Stem Astrocytic Neoplasm

MalaCards organs/tissues related to Brain Stem Astrocytic Neoplasm:

41
Brain, Bone, Spinal Cord

Publications for Brain Stem Astrocytic Neoplasm

Articles related to Brain Stem Astrocytic Neoplasm:

# Title Authors Year
1
Prognostic factors and survival in primary adult high grade brainstem astrocytoma: a population based study from 1973-2008. ( 24674698 )
2014
2
Treatment Outcomes and Prognostic Factors in Pediatric Non-brainstem Astrocytoma in North East of Iran. ( 25250156 )
2014

Variations for Brain Stem Astrocytic Neoplasm

Expression for Brain Stem Astrocytic Neoplasm

Search GEO for disease gene expression data for Brain Stem Astrocytic Neoplasm.

Pathways for Brain Stem Astrocytic Neoplasm

GO Terms for Brain Stem Astrocytic Neoplasm

Sources for Brain Stem Astrocytic Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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