Brain Stem Infarction disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BRN036 MIFTS: 32	Brain Stem Infarction Categories: Cardiovascular diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Brain Stem Infarction

MalaCards integrated aliases for Brain Stem Infarction:

Name: Brain Stem Infarction ¹² ¹⁵

Brain Stem Infarctions ⁴⁴ ⁷³

Brainstem Infarction ¹²

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3523

MeSH ⁴⁴ D020526

SNOMED-CT ⁶⁸ 95457000

UMLS ⁷³ C0521542

Sources

Summaries for Brain Stem Infarction

Disease Ontology : ¹² A brain infarction that is characterized by stroke of the brain stem that develops from blockage or narrowing in the arteries located in the brainstem, has material basis in damage to the cranial nerve nuclei and long tracts, has symptom vertigo, has symptom imbalance, has symptom decreased level of arousal.

MalaCards based summary : Brain Stem Infarction, also known as brain stem infarctions, is related to lateral medullary syndrome and basilar artery occlusion, and has symptoms including vertigo, imbalance and decreased level of arousal. An important gene associated with Brain Stem Infarction is FGB (Fibrinogen Beta Chain), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Miconazole and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and liver.

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Related Diseases for Brain Stem Infarction

Diseases related to Brain Stem Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)

#	Related Disease	Score	Top Affiliating Genes
1	lateral medullary syndrome	31.3	FGB MRPS22 PLG
2	basilar artery occlusion	29.5	APOBEC3G PLG
3	mutism	10.1
4	meningitis	10.0
5	vertebral artery occlusion	9.9
6	internuclear ophthalmoplegia	9.9
7	dysphagia	9.9
8	myoclonus and ataxia	9.7
9	temporal arteritis	9.7
10	trigeminal neuralgia	9.7
11	familial mediterranean fever	9.7
12	moyamoya disease 1	9.7
13	myxedema	9.7
14	partial third-nerve palsy	9.7
15	hypohidrosis	9.7
16	central nervous system vasculitis	9.7
17	vasculitis	9.7
18	tremor	9.7
19	major affective disorder 1	9.7
20	major affective disorder 8	9.7
21	major affective disorder 7	9.7
22	major affective disorder 9	9.7
23	liver disease	9.7
24	stuttering	9.7
25	meningococcal meningitis	9.7
26	nonalcoholic fatty liver disease	9.7
27	panuveitis	9.7
28	syphilis	9.7
29	intracranial hypotension	9.7
30	human immunodeficiency virus infectious disease	9.7
31	rem sleep behavior disorder	9.7
32	fatty liver disease	9.7
33	brainstem auditory evoked responses	9.7
34	nonalcoholic steatohepatitis	9.7
35	postural hypotension	9.7
36	spontaneous intracranial hypotension	9.7

Graphical network of the top 20 diseases related to Brain Stem Infarction:

Sources

Symptoms & Phenotypes for Brain Stem Infarction

Symptoms:

¹²

• vertigo
• imbalance

• decreased level of arousal

Sources

Drugs & Therapeutics for Brain Stem Infarction

Drugs for Brain Stem Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Miconazole

Approved, Investigational, Vet_approved

Phase 2, Phase 3

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin iv

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (tn)

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Sirolimus

Approved, Investigational

Phase 2, Phase 3

53123-88-9

46835353 6436030 5284616

Synonyms:

(-)-rapamycin

(-)-Rapamycin

1fkb

1pbk

23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine

23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine

23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29

3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

53123-88-9

A422989, NSC226080

AC1L1JH9

AC1L7MJ9

AC1L9ZMV

AC-722

Ambotz53123-88-9

Antibiotic AY 22989

AY 22989

AY22989

AY-22989

BIDD:PXR0165

Bio1_000293

Bio1_000782

Bio1_001271

Bio2_000375

Bio2_000855

BiomolKI2_000084

C07909

C51H79NO13

CBiol_002007

CCRIS 9024

CHEBI:100923

CHEBI:9168

CHEMBL413

CID10213190

CID10795871

CID11949238

CID11959112

CID313006

CID478951

CID5040

CID5284616

CID5358081

CID5374464

CID5460439

CID5497196

CID5924240

CID6436030

CID6610270

CID6610346

CID6711160

CID6713081

CID9833581

CID9854379

CID9854380

CID9962926

CID9962928

D00753

DB00877

DE-109

DivK1c_006936

FT-0082351

heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy

HMS2089A21

HSDB 7284

KBio1_001880

KBio2_000410

KBio2_002978

KBio2_005546

KBio3_000779

KBio3_000780

KBioGR_000410

KBioSS_000410

LCP-Siro

LMPK06000003

LS-143290

MLS000028373

MolMap_000043

MolPort-003-959-433

MS-R001

NCGC00021305-05

nchembio.100-comp4

nchembio.2007.42-comp2

nchembio.79-comp1

nchembio762-comp1

nchembio883-comp3

NCI60_001851

NCIMech_000355

NSC 226080

NSC226080

Perceiva

QTL1_000069

R0395_SIAL

R0395_SIGMA

RAP

RAPA

Rapammune

Rapamune

Rapamune (TN)

rapamycin

Rapamycin

Rapamycin (TN)

Rapamycin C-7, analog 4

Rapamycin from Streptomyces hygroscopicus

Rapamycin Immunosuppressant Drug

RPM

S1039_Selleck

SIIA 9268A

SILA 9268A

SILA9268A

sirolimus

Sirolimus

sirolimús

Sirolimus (RAPAMUNE)

Sirolimus (USAN/INN)

Sirolimus [USAN:BAN:INN]

Sirolimus, Rapamune,Rapamycin

sirolimusum

SMP1_000255

SMR000058564

SpecPlus_000840

UNII-W36ZG6FT64

UNM-0000358684

Wy 090217

WY-090217

Everolimus

Approved

Phase 2, Phase 3

159351-69-6

6442177

Synonyms:

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

001, RAD

07741_FLUKA

159351-69-6

40-O-(2-hydroxyethyl)-rapamycin

40-O-(2-Hydroxyethyl)-rapamycin

42-O-(2-Hydroxyethyl)rapamycin

Afinitor

Certican

CERTICAN(R)

CHEMBL1201755

D02714

DB01590

everolimus

Everolimus

Everolimus (JAN/USAN/INN)

Everolimus [USAN]

LS-143292

MolPort-003-847-342

MolPort-003-925-588

NCGC00167512-01

NVP-RAD-001

RAD 001

RAD, SDZ

RAD001

RAD-001

RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus

RAD-001C

S1120_Selleck

SDZ RAD

SDZ-RAD

UNII-9HW64Q8G6G

Zortress

Anti-Infective Agents

Phase 2, Phase 3

Immunologic Factors

Phase 2, Phase 3

Antibiotics, Antitubercular

Phase 2, Phase 3

Antifungal Agents

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3

Immunosuppressive Agents

Phase 2, Phase 3

Pharmaceutical Solutions

Phase 2, Phase 3,Phase 1

Anticonvulsants

Phase 1, Phase 2

Timolol

Approved

Phase 1

26839-75-8

33624 5478

Synonyms:

(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole

(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(S)-timolol

131628-37-0

194288-09-0

26839-75-8

26921-17-5 (maleate (1:1) salt)

AB00513729

AC1L1PYN

AC1Q59QM

Apo-Timol

Apo-Timop

Aquanil

Betim

Betimol

Betimol (TN)

BIDD:GT0073

Blocadren

BPBio1_001008

BRD-K08806317-050-03-6

BSPBio_000916

C07141

C13H24N4O3S

CAS-26921-17-5

CHEBI:9599

CHEMBL499

CID33624

CPD001456519

D08600

DB00373

DB08625

EINECS 248-032-6

HMS2089I11

HSDB 6533

Istalol

L-714,465

Lopac0_001189

Lopac-T-6394

LS-122231

MK-950

NCGC00016038-01

NCGC00016038-02

NCGC00016798-01

NCGC00016798-07

NCGC00022033-02

NCGC00022033-04

NCGC00022033-05

Novo-Timol

Nu-Timolol

Oprea1_640981

Optimol

Phoxal-timolol

Prestwick0_000948

Prestwick1_000948

Prestwick2_000948

Prestwick3_000948

Proflax

S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole

S(-)-Timolol maleate

SAM002564238

SPBio_003075

ST072193

Temserin

Tenopt

TIM

Timacar

Timacor

Tim-AK

timolol

Timolol

Timolol (INN)

Timolol (TN)

Timolol [USAN]

Timolol anhydrous

Timolol GFS

Timolol maleate

Timolol Maleate, (1:1) Salt

Timololo

Timololum

Timololum [INN-Latin]

Timopic

Timoptic

Timoptic in Ocudose

Timoptic OcuDose

Timoptic-XE

Timoptol

Tocris-0649

UNII-817W3C6175

Maleic acid

Experimental

Phase 1

110-16-7

444266

Synonyms:

(2E)-2-Butenedioate

(2E)-2-Butenedioic acid

(2E)-But-2-enedioate

(2E)-But-2-enedioic acid

(e)-2-Butenedioate

(e)-2-Butenedioic acid

2-(e)-Butenedioate

2-(e)-Butenedioic acid

Allomaleate

Allomaleic acid

Ammonium fumarate

Boletate

Boletic acid

e297

FC 33

Fumarate

Fumarsaeure

Furamag

Lichenate

Lichenic acid

Magnesium fumarate

Sodium fumarate

trans-1,2-Ethylenedicarboxylate

trans-1,2-Ethylenedicarboxylic acid

trans-2-Butenedioate

trans-2-Butenedioic acid

trans-But-2-enedioate

trans-But-2-enedioic acid

trans-Butenedioate

trans-Butenedioic acid

Anti-Arrhythmia Agents

Phase 1

Adrenergic beta-Antagonists

Phase 1

Adrenergic Agents

Phase 1

Neurotransmitter Agents

Phase 1

Ophthalmic Solutions

Phase 1

Antihypertensive Agents

Phase 1

Adrenergic Antagonists

Phase 1

Lubricant Eye Drops

Phase 1

Immunoglobulins

Antibodies

GTPase-Activating Proteins

Not Applicable

Interventional clinical trials:

(show all 16)

#	Name	Status	NCT ID	Phase	Drugs
1	Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome	Recruiting	NCT03047980	Phase 2, Phase 3	Sirolimus
2	Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome	Completed	NCT02080624	Phase 2	Drug: Topical Rapamycin
3	Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome	Active, not recruiting	NCT02332655	Phase 1, Phase 2	Cannabidiol
4	Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)	Withdrawn	NCT01997255	Phase 2	Everolimus
5	Use of the Atkins Diet for Children With Sturge Weber Syndrome	Completed	NCT00639730	Phase 1
6	Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol	Recruiting	NCT01533376	Phase 1	Timolol;Preservative free artificial tear gel.
7	ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis	Completed	NCT01393444	Not Applicable
8	Transcranial Direct Current Stimulation for Dysphagia Therapy in Acute Stroke Patients	Completed	NCT01970384	Not Applicable
9	Biomarker Development in Sturge-Weber Syndrome	Completed	NCT01345305
10	Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)	Completed	NCT00610402
11	Cortical Recording and Stimulating Array Brain-Machine Interface	Recruiting	NCT01894802	Not Applicable
12	Investigation on the Cortical Communication (CortiCom) System	Recruiting	NCT03567213	Not Applicable
13	BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia	Recruiting	NCT00912041	Not Applicable
14	Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome	Recruiting	NCT01425944
15	French National Cohort of Children With Port Wine Stain	Active, not recruiting	NCT01364857	Not Applicable
16	NeuroCognitive Communicator: Safety Study	Not yet recruiting	NCT03100110	Not Applicable

Search NIH Clinical Center for Brain Stem Infarction

Cochrane evidence based reviews: brain stem infarctions

Sources

Genetic Tests for Brain Stem Infarction

Sources

Anatomical Context for Brain Stem Infarction

MalaCards organs/tissues related to Brain Stem Infarction:

⁴¹

Brain, Cerebellum, Liver

The Foundational Model of Anatomy Ontology organs/tissues related to Brain Stem Infarction:

¹⁹

The Brainstem

Sources

Publications for Brain Stem Infarction

Articles related to Brain Stem Infarction:

(show all 44)

#	Title	Authors	Year
1	Herpetic cranial polyneuritis mimicking brain stem infarction-an atypical presentation of Ramsay Hunt syndrome. ( 27251418 )	Bharadwaj S....Bharadwaj A.	2016
2	Brain Stem Infarction Due to Basilar Artery Dissection in a Patient with Moyamoya Disease Four Years after Successful Bilateral Revascularization Surgeries. ( 27068774 )	Abe T....Tominaga T.	2016
3	Bilateral cerebellar and brain stem infarction resulting from vertebral artery injury following cervical trauma without radiographic damage of the spinal column: a case report. ( 24061492 )		2014
4	&quot;Invisible&quot; brain stem infarction at the first day. ( 24809672 )		2014
5	Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis. ( 23710607 )		2013
6	Fatal outcome after brain stem infarction related to bilateral vertebral artery occlusion - case report of a detrimental complication of cervical spine trauma. ( 21756312 )		2011
7	Partial third nerve palsy involving the superior rectus and levator palpebrae muscles and distruption of central binocular vision fusion from brain stem infarction: a case report. ( 19807689 )	Khawam E....Hamam R.	2009
8	Successful treatment of pulmonary aspiration due to brain stem infarction by using cough exercise based on swallowing scintigraphy: preliminary observations. ( 19387737 )		2009
9	Brain stem infarction caused by proximal internal carotid artery stenosis in a patient with a persisting primitive trigeminal artery. ( 16766871 )	Foerch C....Neumann-Haefelin T.	2006
10	Brain stem infarction: a complication of microvascular decompression for trigeminal neuralgia. ( 16936412 )	Singh D....Sinha S.	2006
11	Re: Poor surgical technique in cervical plating leading to vertebral artery injury and brain stem infarction--case report (Cho KH, Shin YS, Yoon SH, et al, Surg Neurol 2005;64:221-5). ( 16488269 )		2006
12	Poor surgical technique in cervical plating leading to vertebral artery injury and brain stem infarction--case report. ( 16099249 )	Cho K.H....Cho K.G.	2005
13	Electro-acupuncture for treatment of dysequillibrium due to cerebellum or brain stem infarction. ( 14719296 )	Zhao H....Liu X.	2003
14	Vertebrobasilar artery dissection presenting with simultaneous subarachnoid hemorrhage and brain stem infarction: case report. ( 12633950 )	Murakami K....Nishijima M.	2003
15	Time course of lesion development in patients with acute brain stem infarction and correlation with NIHSS score. ( 11566246 )		2001
16	Transient mutism after brain stem infarction. ( 10809658 )	ErA9ahin Y.	2000
17	Natural course of combined limb and palatal tremor caused by cerebellar-brain stem infarction. ( 10495051 )	Yanagisawa T....Murayama M.	1999
18	Transient mutism after brain stem infarction. ( 10610613 )	ErA9ahin Y.	1999
19	Transient mutism after brain stem infarction. ( 10481795 )	ErA9ahin Y.	1999
20	Transient mutism resolving into cerebellar speech after brain stem infarction following a traumatic injury of the vertebral artery in a child. ( 10189505 )	Miyakita Y....Kitagawa H.	1999
21	Xenon contrast-enhanced CT imaging of supratentorial hypoperfusion in patients with brain stem infarction. ( 10588109 )		1999
22	Transient mutism after brain stem infarction. ( 10672311 )		1999
23	Transient mutism after brain stem infarction (ref. Acta Neurochirurgia 1999, 141: 209-213) ( 10536732 )		1999
24	The protective effect of a persistent trigeminal artery on brain stem infarctions: a follow-up case report. ( 9617875 )	Ito Y...Yanagi T	1998
25	Aberrant distribution of tyrosine hydroxylase and substance P in infants with brain-stem infarction. ( 7524264 )	Nishimura A....Becker L.E.	1994
26	Ipsilateral hypohidrosis in brain stem infarction. ( 8418531 )	Korpelainen J.T....MyllylAo V.V.	1993
27	Brain stem infarction and diaschisis. A SPECT cerebral perfusion study. ( 8342190 )	Fazekas F....Flooh E.	1993
28	Pediatric brain stem infarction caused by a basilar and vertebral artery occlusion: case report. ( 1513445 )	Ishikawa T....Takei H.	1992
29	Bilateral persistent trigeminal arteries presenting with brain-stem infarction. ( 1528434 )	Okada Y....Kagawa R.	1992
30	Transient amnesia heralding brain stem infarction. ( 1431969 )	Howard R.S....Ron M.	1992
31	Isolated inferior oblique paresis from brain-stem infarction. Perspective on oculomotor fascicular organization in the ventral midbrain tegmentum. ( 2405823 )	Castro O....Mamourian A.C.	1990
32	Transcranial Doppler in acute brain stem infarction. ( 2565551 )	Shepard D.L....Halsey J.H.	1989
33	Brain stem infarction as a complication of giant-cell arteritis. ( 3757384 )		1986
34	Megadolichobasilar anomaly associated with brain stem infarction: a case report. ( 3971740 )	Shirakuni T....Fujiwara M.	1985
35	Brain stem infarction due to chiropractic manipulation of the cervical spine. ( 6612409 )		1983
36	Brain stem infarction due to chiropractic manipulation of the cervical spine. ( 6359460 )		1983
37	Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction. ( 314229 )		1979
38	Respiratory rate and pattern disturbances in acute brain stem infarction. ( 960158 )	Lee M.C....Resch J.A.	1976
39	Characteristics and survival of patients with brain stem infarction. ( 1154470 )	Fogelhol R....Aho K.	1975
40	'Iatrogenic' brain stem infarction. A complication of x-ray examination of the cervical spine and following posterior tamponation of the nose. ( 1126348 )		1975
41	Insulin-resistant diabetic coma. Acute onset in an unknown diabetic associated with brain-stem infarction and death. ( 4212098 )	Siegel A.J....Bell W.R.	1974
42	See-saw nystagmus: an unusual sign of brain-stem infarction. ( 4847304 )	Mastaglia F.L.	1974
43	Sleep patterns in a patient with a brain stem infarction involving the raphe nucleus. ( 4135364 )		1974
44	Electroencephalogram in brain stem infarction. ( 13737459 )	POTES J....Wells C.E.	1961

Sources

Genes for Brain Stem Infarction

Genes related to Brain Stem Infarction (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	FGB	Fibrinogen Beta Chain	Protein Coding	14.7	DISEASES inferred ¹⁵
2	APOBEC3G	Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3G	Protein Coding	14.65	DISEASES inferred ¹⁵
3	CNOT3	CCR4-NOT Transcription Complex Subunit 3	Protein Coding	14.55	DISEASES inferred ¹⁵
4	PLG	Plasminogen	Protein Coding	14.46	DISEASES inferred ¹⁵
5	LIPN	Lipase Family Member N	Protein Coding	14.41	DISEASES inferred ¹⁵
6	MRPS22	Mitochondrial Ribosomal Protein S22	Protein Coding	14.37	DISEASES inferred ¹⁵

Sources

Variations for Brain Stem Infarction

Sources

Expression for Brain Stem Infarction

Search GEO for disease gene expression data for Brain Stem Infarction.

Sources

Pathways for Brain Stem Infarction

Pathways related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade) ⁶⁶ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁵ Common Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Prothrombin Activation Pathway ⁶⁴ Intrinsic Pathway of Fibrin Clot Formation ⁶⁶	11.36	FGB PLG
2	Complement and coagulation cascades ¹ ³⁷	11.1	FGB PLG
3	Cell adhesion_Plasmin signaling ²²	10.31	FGB PLG

Sources

GO Terms for Brain Stem Infarction

Cellular components related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	blood microparticle	GO:0072562	9.16	FGB PLG
2	P-body	GO:0000932	8.96	APOBEC3G CNOT3
3	platelet alpha granule lumen	GO:0031093	8.62	FGB PLG

Biological processes related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	blood coagulation	GO:0007596	9.26	FGB PLG
2	platelet degranulation	GO:0002576	9.16	FGB PLG
3	hemostasis	GO:0007599	8.96	FGB PLG
4	fibrinolysis	GO:0042730	8.62	FGB PLG

Molecular functions related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chaperone binding	GO:0051087	8.62	FGB PLG

Sources

Sources for Brain Stem Infarction

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia