Brain Stem Infarction disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: BRN036 MIFTS: 38	Brain Stem Infarction Categories: Cardiovascular diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Brain Stem Infarction

MalaCards integrated aliases for Brain Stem Infarction:

Name: Brain Stem Infarction ¹² ¹⁵ ¹⁷

Brain Stem Infarctions ⁴⁵ ⁷⁴

Brainstem Infarction ¹²

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3523

MeSH ⁴⁵ D020526

SNOMED-CT ⁶⁹ 95457000

EFO ¹⁷ EFO_1000847

UMLS ⁷⁴ C0521542

Sources

Summaries for Brain Stem Infarction

Disease Ontology : ¹² A brain infarction that is characterized by stroke of the brain stem that develops from blockage or narrowing in the arteries located in the brainstem, has material basis in damage to the cranial nerve nuclei and long tracts, has symptom vertigo, has symptom imbalance, has symptom decreased level of arousal.

MalaCards based summary : Brain Stem Infarction, also known as brain stem infarctions, is related to lateral medullary syndrome and basilar artery occlusion, and has symptoms including vertigo, imbalance and decreased level of arousal. An important gene associated with Brain Stem Infarction is SRPK2 (SRSF Protein Kinase 2), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Sirolimus and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and eye.

Sources

Related Diseases for Brain Stem Infarction

Diseases related to Brain Stem Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)

#	Related Disease	Score	Top Affiliating Genes
1	lateral medullary syndrome	31.1	FGB PLG
2	basilar artery occlusion	29.3	APOBEC3G PLG
3	mutism	10.2
4	meningitis	10.0
5	vertebral artery occlusion	9.9
6	internuclear ophthalmoplegia	9.9
7	herpes zoster	9.9
8	dysphagia	9.9
9	myoclonus and ataxia	9.8
10	trigeminal neuralgia	9.8
11	down syndrome	9.8
12	familial mediterranean fever	9.8
13	moyamoya disease 1	9.8
14	myxedema	9.8
15	ocular motor apraxia	9.8
16	partial third-nerve palsy	9.8
17	amnestic disorder	9.8
18	anhidrosis	9.8
19	carotid stenosis	9.8
20	central nervous system vasculitis	9.8
21	vasculitis	9.8
22	pathologic nystagmus	9.8
23	polyarteritis nodosa	9.8
24	tremor	9.8
25	major affective disorder 1	9.7
26	major affective disorder 8	9.7
27	major affective disorder 7	9.7
28	major affective disorder 9	9.7
29	liver disease	9.7
30	stuttering	9.7
31	meningococcal meningitis	9.7
32	nonalcoholic fatty liver disease	9.7
33	panuveitis	9.7
34	mental depression	9.7
35	syphilis	9.7
36	intracranial hypotension	9.7
37	human immunodeficiency virus infectious disease	9.7
38	rem sleep behavior disorder	9.7
39	fatty liver disease	9.7
40	bacterial meningitis	9.7
41	brainstem auditory evoked responses	9.7
42	depression	9.7
43	encephalopathy	9.7
44	spontaneous intracranial hypotension	9.7

Graphical network of the top 20 diseases related to Brain Stem Infarction:

Sources

Symptoms & Phenotypes for Brain Stem Infarction

Symptoms:

¹²

• vertigo
• imbalance

• decreased level of arousal

Sources

Drugs & Therapeutics for Brain Stem Infarction

Drugs for Brain Stem Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Sirolimus

Approved, Investigational

Phase 2, Phase 3

53123-88-9

46835353 5284616 6436030

Synonyms:

(-)-rapamycin

(-)-Rapamycin

1fkb

1pbk

23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine

23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine

23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29

3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

53123-88-9

A422989, NSC226080

AC1L1JH9

AC1L7MJ9

AC1L9ZMV

AC-722

Ambotz53123-88-9

Antibiotic AY 22989

AY 22989

AY22989

AY-22989

BIDD:PXR0165

Bio1_000293

Bio1_000782

Bio1_001271

Bio2_000375

Bio2_000855

BiomolKI2_000084

C07909

C51H79NO13

CBiol_002007

CCRIS 9024

CHEBI:100923

CHEBI:9168

CHEMBL413

CID10213190

CID10795871

CID11949238

CID11959112

CID313006

CID478951

CID5040

CID5284616

CID5358081

CID5374464

CID5460439

CID5497196

CID5924240

CID6436030

CID6610270

CID6610346

CID6711160

CID6713081

CID9833581

CID9854379

CID9854380

CID9962926

CID9962928

D00753

DB00877

DE-109

DivK1c_006936

FT-0082351

heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy

HMS2089A21

HSDB 7284

KBio1_001880

KBio2_000410

KBio2_002978

KBio2_005546

KBio3_000779

KBio3_000780

KBioGR_000410

KBioSS_000410

LCP-Siro

LMPK06000003

LS-143290

MLS000028373

MolMap_000043

MolPort-003-959-433

MS-R001

NCGC00021305-05

nchembio.100-comp4

nchembio.2007.42-comp2

nchembio.79-comp1

nchembio762-comp1

nchembio883-comp3

NCI60_001851

NCIMech_000355

NSC 226080

NSC226080

Perceiva

QTL1_000069

R0395_SIAL

R0395_SIGMA

RAP

RAPA

Rapammune

Rapamune

Rapamune (TN)

rapamycin

Rapamycin

Rapamycin (TN)

Rapamycin C-7, analog 4

Rapamycin from Streptomyces hygroscopicus

Rapamycin Immunosuppressant Drug

RPM

S1039_Selleck

SIIA 9268A

SILA 9268A

SILA9268A

sirolimus

Sirolimus

Sirolimús

Sirolimus (RAPAMUNE)

Sirolimus (USAN/INN)

Sirolimus [USAN:BAN:INN]

Sirolimus, Rapamune,Rapamycin

Sirolimusum

SMP1_000255

SMR000058564

SpecPlus_000840

UNII-W36ZG6FT64

UNM-0000358684

Wy 090217

WY-090217

Everolimus

Approved

Phase 2, Phase 3

159351-69-6

70789204 6442177

Synonyms:

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

001, RAD

07741_FLUKA

159351-69-6

40-O-(2-hydroxyethyl)-rapamycin

40-O-(2-Hydroxyethyl)-rapamycin

42-O-(2-Hydroxyethyl)rapamycin

Afinitor

Certican

CERTICAN(R)

CHEMBL1201755

D02714

DB01590

everolimus

Everolimus

évérolimus

Everolimus (JAN/USAN/INN)

Everolimus [USAN]

LS-143292

MolPort-003-847-342

MolPort-003-925-588

NCGC00167512-01

NVP-RAD-001

RAD 001

RAD, SDZ

RAD001

RAD-001

RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus

RAD-001C

S1120_Selleck

SDZ RAD

SDZ-RAD

UNII-9HW64Q8G6G

Zortress

Miconazole

Approved, Investigational, Vet_approved

Phase 2, Phase 3

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Immunologic Factors

Phase 2, Phase 3

Antibiotics, Antitubercular

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3

Immunosuppressive Agents

Phase 2, Phase 3

Antifungal Agents

Phase 2, Phase 3

Anti-Infective Agents

Phase 2, Phase 3

Pharmaceutical Solutions

Phase 2, Phase 3,Phase 1

Anticonvulsants

Phase 1, Phase 2

Epidiolex

Phase 1, Phase 2

Timolol

Approved

Phase 1

26839-75-8

5478 33624

Synonyms:

(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole

(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol

(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol

(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

(S)-timolol

131628-37-0

194288-09-0

26839-75-8

26921-17-5 (maleate (1:1) salt)

AB00513729

AC1L1PYN

AC1Q59QM

Apo-Timol

Apo-Timop

Aquanil

Betim

Betimol

Betimol (TN)

BIDD:GT0073

Blocadren

BPBio1_001008

BRD-K08806317-050-03-6

BSPBio_000916

C07141

C13H24N4O3S

CAS-26921-17-5

CHEBI:9599

CHEMBL499

CID33624

CPD001456519

D08600

DB00373

DB08625

EINECS 248-032-6

HMS2089I11

HSDB 6533

Istalol

L-714,465

Lopac0_001189

Lopac-T-6394

LS-122231

MK-950

NCGC00016038-01

NCGC00016038-02

NCGC00016798-01

NCGC00016798-07

NCGC00022033-02

NCGC00022033-04

NCGC00022033-05

Novo-Timol

Nu-Timolol

Oprea1_640981

Optimol

Phoxal-timolol

Prestwick0_000948

Prestwick1_000948

Prestwick2_000948

Prestwick3_000948

Proflax

S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole

S(-)-Timolol maleate

SAM002564238

SPBio_003075

ST072193

Temserin

Tenopt

TIM

Timacar

Timacor

Tim-AK

timolol

Timolol

Timolol (INN)

Timolol (TN)

Timolol [USAN]

Timolol anhydrous

Timolol GFS

Timolol maleate

Timolol Maleate, (1:1) Salt

Timololo

Timololum

Timololum [INN-Latin]

Timopic

Timoptic

Timoptic in Ocudose

Timoptic OcuDose

Timoptic-XE

Timoptol

Tocris-0649

UNII-817W3C6175

Maleic acid

Experimental, Investigational

Phase 1

110-17-8, 110-16-7

444972

Synonyms:

(2E)-2-Butenedioate

(2E)-2-butenedioic acid

(2E)-2-Butenedioic acid

(2E)-But-2-enedioate

(2E)-but-2-enedioic acid

(2E)-But-2-enedioic acid

(e)-2-Butenedioate

(e)-2-Butenedioic acid

(E)-2-butenedioic acid

(E)-2-Butenedioic acid

(E)-but-2-enedioic acid

03761_FLUKA

1,2-Ethylenedicarboxylic acid, (E)

110-17-8

2-(e)-Butenedioate

2-(e)-Butenedioic acid

2-(E)-Butenedioic acid

240745_ALDRICH

240745_SIAL

26B3632D-E93F-4655-90B0-3C17855294BA

2-Butenedioic acid

2-Butenedioic acid (2E)- (9CI)

4-02-00-02202 (Beilstein Handbook Reference)

623158-97-4

AB1002616

AC1L9H76

AC1Q5T7Y

AC1Q71EM

Acidum fumaricum

AI3-24236

AKOS000118896

Allomaleate

Allomaleic acid

Allomalenic acid

ammonium fumarate

Ammonium fumarate

AR-1D9767

bmse000083

Boletate

Boletic acid

BRN 0605763

But-2-enedioic acid

Butenedioic acid

C00122

C4H4O4

Caswell No. 465E

CCRIS 1039

CHEBI:18012

CHEBI:22958

CHEMBL503160

CID444972

D02308

DB04299

e297

E-2-Butenedioic acid

EINECS 203-743-0

EPA Pesticide Chemical Code 051201

F0067

F8509_SIGMA

FC 33

FC 33 (acid)

FEMA No. 2488

FEMA Number 2488

fum

fumarate

Fumarate

fumarate, 10

fumaric acid

Fumaric acid (8CI)

Fumaric acid (NF)

Fumaricum acidum

Fumarsaeure

Fumarsäure

Furamag

HSDB 710

I04-1070

Kyselina fumarova

Kyselina fumarova [Czech]

Lichenate

Lichenic acid

Lichenic acid (VAN)

LMFA01170106

LS-500

Magnesium fumarate

MLS002454406

MolPort-001-780-031

MolPort-004-288-293

NCGC00091192-01

nchembio.186-comp71

nchembio.2007.47-comp1

NSC2752

NSC-2752

OR17920

S04-0167

SMR000112117

Sodium fumarate

trans-1,2-Ethylenedicarboxylate

trans-1,2-ethylenedicarboxylic acid

trans-1,2-Ethylenedicarboxylic acid

trans-2-Butenedioate

trans-2-Butenedioic acid

trans-But-2-enedioate

trans-but-2-enedioic acid

trans-But-2-enedioic acid

trans-Butenedioate

trans-Butenedioic acid

Tumaric acid

U-1149

UNII-88XHZ13131

USAF EK-P-583

W248800_ALDRICH

WLN: QV1U1VQ-T

Neurotransmitter Agents

Phase 1

Lubricant Eye Drops

Phase 1

Adrenergic Agents

Phase 1

Adrenergic Antagonists

Phase 1

Antihypertensive Agents

Phase 1

Anti-Arrhythmia Agents

Phase 1

Ophthalmic Solutions

Phase 1

Adrenergic beta-Antagonists

Phase 1

Immunoglobulins

Antibodies

GTPase-Activating Proteins

Not Applicable

Interventional clinical trials:

(show all 16)

#	Name	Status	NCT ID	Phase	Drugs
1	Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome	Recruiting	NCT03047980	Phase 2, Phase 3	Sirolimus
2	Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome	Completed	NCT02080624	Phase 2	Drug: Topical Rapamycin
3	Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome	Active, not recruiting	NCT02332655	Phase 1, Phase 2	Cannabidiol
4	Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)	Withdrawn	NCT01997255	Phase 2	Everolimus
5	Use of the Atkins Diet for Children With Sturge Weber Syndrome	Completed	NCT00639730	Phase 1
6	Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol	Terminated	NCT01533376	Phase 1	Timolol;Preservative free artificial tear gel.
7	ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis	Completed	NCT01393444	Not Applicable
8	Transcranial Direct Current Stimulation for Dysphagia Therapy in Acute Stroke Patients	Completed	NCT01970384	Not Applicable
9	Biomarker Development in Sturge-Weber Syndrome	Completed	NCT01345305
10	Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)	Completed	NCT00610402
11	Cortical Recording and Stimulating Array Brain-Machine Interface	Recruiting	NCT01894802	Not Applicable
12	Investigation on the Cortical Communication (CortiCom) System	Recruiting	NCT03567213	Not Applicable
13	BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia	Recruiting	NCT00912041	Not Applicable
14	Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome	Recruiting	NCT01425944
15	French National Cohort of Children With Port Wine Stain	Active, not recruiting	NCT01364857	Not Applicable
16	NeuroCognitive Communicator: Safety Study	Not yet recruiting	NCT03100110	Not Applicable

Search NIH Clinical Center for Brain Stem Infarction

Cochrane evidence based reviews: brain stem infarctions

Sources

Genetic Tests for Brain Stem Infarction

Sources

Anatomical Context for Brain Stem Infarction

MalaCards organs/tissues related to Brain Stem Infarction:

⁴²

Brain, Liver, Eye, Cerebellum

The Foundational Model of Anatomy Ontology organs/tissues related to Brain Stem Infarction:

²⁰

The Brainstem

Sources

Publications for Brain Stem Infarction

Articles related to Brain Stem Infarction:

(show all 45)

#	Title	Authors	Year
1	Brain stem infarction in a 6-year-old boy with Down syndrome. ( 30857880 )	Imagi T...Matsuishi T	2019
2	Brain Stem Infarction Due to Basilar Artery Dissection in a Patient with Moyamoya Disease Four Years after Successful Bilateral Revascularization Surgeries. ( 27068774 )	Abe T...Tominaga T	2016
3	Herpetic cranial polyneuritis mimicking brain stem infarction-an atypical presentation of Ramsay Hunt syndrome. ( 27251418 )	Bharadwaj S...Bharadwaj A	2016
4	Bilateral cerebellar and brain stem infarction resulting from vertebral artery injury following cervical trauma without radiographic damage of the spinal column: a case report. ( 24061492 )	Mimata Y...Suzuki Y	2014
5	"Invisible" brain stem infarction at the first day. ( 24809672 )	Tsuyusaki Y...Inaoka T	2014
6	Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis. ( 23710607 )	Luger S...Foerch C	2013
7	Fatal outcome after brain stem infarction related to bilateral vertebral artery occlusion - case report of a detrimental complication of cervical spine trauma. ( 21756312 )	Yoshihara H...Stahel PF	2011
8	Successful treatment of pulmonary aspiration due to brain stem infarction by using cough exercise based on swallowing scintigraphy: preliminary observations. ( 19387737 )	Kanai N...Majima M	2009
9	Partial third nerve palsy involving the superior rectus and levator palpebrae muscles and distruption of central binocular vision fusion from brain stem infarction: a case report. ( 19807689 )	Khawam E...Hamam R	2009
10	Re: Poor surgical technique in cervical plating leading to vertebral artery injury and brain stem infarction--case report (Cho KH, Shin YS, Yoon SH, et al, Surg Neurol 2005;64:221-5). ( 16488269 )	Dickerman RD...Morgan B	2006
11	Brain stem infarction caused by proximal internal carotid artery stenosis in a patient with a persisting primitive trigeminal artery. ( 16766871 )	Foerch C...Neumann-Haefelin T	2006
12	Brain stem infarction: a complication of microvascular decompression for trigeminal neuralgia. ( 16936412 )	Singh D...Sinha S	2006
13	Poor surgical technique in cervical plating leading to vertebral artery injury and brain stem infarction--case report. ( 16099249 )	Cho KH...Cho KG	2005
14	Electro-acupuncture for treatment of dysequillibrium due to cerebellum or brain stem infarction. ( 14719296 )	Zhao H...Liu X	2003
15	Vertebrobasilar artery dissection presenting with simultaneous subarachnoid hemorrhage and brain stem infarction: case report. ( 12633950 )	Murakami K...Nishijima M	2003
16	Time course of lesion development in patients with acute brain stem infarction and correlation with NIHSS score. ( 11566246 )	Fitzek S...Stoeter P	2001
17	Transient mutism after brain stem infarction. ( 10809658 )	Er?ahin Y	2000
18	Transient mutism resolving into cerebellar speech after brain stem infarction following a traumatic injury of the vertebral artery in a child. ( 10189505 )	Miyakita Y...Kitagawa H	1999
19	Transient mutism after brain stem infarction. ( 10481795 )	Er?ahin Y	1999
20	Natural course of combined limb and palatal tremor caused by cerebellar-brain stem infarction. ( 10495051 )	Yanagisawa T...Murayama M	1999
21	Transient mutism after brain stem infarction (ref. Acta Neurochirurgia 1999, 141: 209-213) ( 10536732 )	Er?ahin Y	1999
22	Xenon contrast-enhanced CT imaging of supratentorial hypoperfusion in patients with brain stem infarction. ( 10588109 )	Miyazawa N...Nukui H	1999
23	Transient mutism after brain stem infarction. ( 10610613 )	Er?ahin Y	1999
24	Transient mutism after brain stem infarction. ( 10672311 )	Er?ahin Y	1999
25	The protective effect of a persistent trigeminal artery on brain stem infarctions: a follow-up case report. ( 9617875 )	Ito Y...Yanagi T	1998
26	Aberrant distribution of tyrosine hydroxylase and substance P in infants with brain-stem infarction. ( 7524264 )	Nishimura A...Becker LE	1994
27	Brain stem infarction and diaschisis. A SPECT cerebral perfusion study. ( 8342190 )	Fazekas F...Flooh E	1993
28	Ipsilateral hypohidrosis in brain stem infarction. ( 8418531 )	Korpelainen JT...Myllyl? VV	1993
29	Transient amnesia heralding brain stem infarction. ( 1431969 )	Howard RS...Ron M	1992
30	Pediatric brain stem infarction caused by a basilar and vertebral artery occlusion: case report. ( 1513445 )	Ishikawa T...Takei H	1992
31	Bilateral persistent trigeminal arteries presenting with brain-stem infarction. ( 1528434 )	Okada Y...Kagawa R	1992
32	Isolated inferior oblique paresis from brain-stem infarction. Perspective on oculomotor fascicular organization in the ventral midbrain tegmentum. ( 2405823 )	Castro O...Mamourian AC	1990
33	Transcranial Doppler in acute brain stem infarction. ( 2565551 )	Shepard DL...Halsey JH	1989
34	Brain stem infarction as a complication of giant-cell arteritis. ( 3757384 )	Michotte A...Ebinger G	1986
35	Megadolichobasilar anomaly associated with brain stem infarction: a case report. ( 3971740 )	Shirakuni T...Fujiwara M	1985
36	Brain stem infarction due to chiropractic manipulation of the cervical spine. ( 6359460 )	Braun IF...Zimmerman RD	1983
37	Brain stem infarction due to chiropractic manipulation of the cervical spine. ( 6612409 )	Braun IF...Zimmerman RD	1983
38	Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction. ( 314229 )	Sturm V...Stock G	1979
39	Respiratory rate and pattern disturbances in acute brain stem infarction. ( 960158 )	Lee MC...Resch JA	1976
40	'Iatrogenic' brain stem infarction. A complication of x-ray examination of the cervical spine and following posterior tamponation of the nose. ( 1126348 )	Fogelholm R...Karli P	1975
41	Characteristics and survival of patients with brain stem infarction. ( 1154470 )	Fogelhol R...Aho K	1975
42	Sleep patterns in a patient with a brain stem infarction involving the raphe nucleus. ( 4135364 )	Freemon FR...Ward JW	1974
43	Insulin-resistant diabetic coma. Acute onset in an unknown diabetic associated with brain-stem infarction and death. ( 4212098 )	Siegel AJ...Bell WR	1974
44	See-saw nystagmus: an unusual sign of brain-stem infarction. ( 4847304 )	Mastaglia FL	1974
45	Electroencephalogram in brain stem infarction. ( 13737459 )	POTES J...WELLS CE	1961

Sources

Genes for Brain Stem Infarction

Genes related to Brain Stem Infarction (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SRPK2	SRSF Protein Kinase 2	Protein Coding	15.11	DISEASES inferred ¹⁵
2	FGB	Fibrinogen Beta Chain	Protein Coding	14.75	DISEASES inferred ¹⁵
3	APOBEC3G	Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3G	Protein Coding	14.63	DISEASES inferred ¹⁵
4	CNOT3	CCR4-NOT Transcription Complex Subunit 3	Protein Coding	14.56	DISEASES inferred ¹⁵
5	PLG	Plasminogen	Protein Coding	14.48	DISEASES inferred ¹⁵
6	LIPN	Lipase Family Member N	Protein Coding	14.43	DISEASES inferred ¹⁵

Sources

Variations for Brain Stem Infarction

Sources

Expression for Brain Stem Infarction

Search GEO for disease gene expression data for Brain Stem Infarction.

Sources

Pathways for Brain Stem Infarction

Pathways related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade) ⁶⁷ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁶ Common Pathway of Fibrin Clot Formation ⁶⁷ Extrinsic Pathway of Fibrin Clot Formation ⁶⁷ Extrinsic Prothrombin Activation Pathway ⁶⁵ Intrinsic Pathway of Fibrin Clot Formation ⁶⁷	11.36	FGB PLG
2	Complement and coagulation cascades ¹ ³⁸	11.1	FGB PLG
3	Cell adhesion_Plasmin signaling ²³	10.31	FGB PLG

Sources

GO Terms for Brain Stem Infarction

Cellular components related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	blood microparticle	GO:0072562	9.16	FGB PLG
2	P-body	GO:0000932	8.96	APOBEC3G CNOT3
3	platelet alpha granule lumen	GO:0031093	8.62	FGB PLG

Biological processes related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	innate immune response	GO:0045087	9.43	APOBEC3G FGB SRPK2
2	blood coagulation	GO:0007596	9.37	FGB PLG
3	platelet degranulation	GO:0002576	9.32	FGB PLG
4	hemostasis	GO:0007599	9.16	FGB PLG
5	negative regulation of viral genome replication	GO:0045071	8.96	APOBEC3G SRPK2
6	fibrinolysis	GO:0042730	8.62	FGB PLG

Molecular functions related to Brain Stem Infarction according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chaperone binding	GO:0051087	8.62	FGB PLG

Sources

Sources for Brain Stem Infarction

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia