MCID: BRN026
MIFTS: 36

Branch Retinal Artery Occlusion

Categories: Cardiovascular diseases, Eye diseases

Aliases & Classifications for Branch Retinal Artery Occlusion

MalaCards integrated aliases for Branch Retinal Artery Occlusion:

Name: Branch Retinal Artery Occlusion 12 15 74
Retinal Artery Occlusion 45 74
Arterial Retinal Branch Occlusion 12
Retinal Arterial Branch Occlusion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13094
ICD9CM 36 362.32
MeSH 45 D015356
NCIt 51 C34436
SNOMED-CT 69 50821009
ICD10 34 H34.23

Summaries for Branch Retinal Artery Occlusion

MalaCards based summary : Branch Retinal Artery Occlusion, also known as retinal artery occlusion, is related to retinal vascular occlusion and retinal artery occlusion, and has symptoms including amaurosis fugax An important gene associated with Branch Retinal Artery Occlusion is MTHFR (Methylenetetrahydrofolate Reductase). The drugs Ranibizumab and Angiogenesis Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and endothelial.

Related Diseases for Branch Retinal Artery Occlusion

Diseases related to Branch Retinal Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 212)
# Related Disease Score Top Affiliating Genes
1 retinal vascular occlusion 32.2 FANCG MTHFR SERPINC1
2 retinal artery occlusion 31.9 MTHFR SERPINC1
3 retinal vein occlusion 30.9 MTHFR SERPINC1
4 central retinal vein occlusion 30.6 MTHFR SERPINC1
5 ischemic optic neuropathy 30.3 MTHFR SERPINC1
6 nonarteritic anterior ischemic optic neuropathy 30.3 MTHFR SERPINC1
7 antiphospholipid syndrome 30.2 MTHFR SERPINC1
8 patent foramen ovale 30.1 MTHFR SERPINC1
9 thrombosis 30.1 MTHFR SERPINC1
10 protein s deficiency 30.1 MTHFR SERPINC1
11 thrombophilia 30.1 MTHFR SERPINC1
12 homocysteinemia 30.0 MTHFR SERPINC1
13 stroke, ischemic 29.9 MTHFR SERPINC1
14 homocystinuria 29.8 MTHFR SERPINC1
15 arteritic anterior ischemic optic neuropathy 29.8 FANCG MTHFR
16 transient retinal arterial occlusion 12.4
17 partial arterial retinal occlusion 11.8
18 susac syndrome 11.7
19 retinal ischemia 11.7
20 lupus erythematosus 10.3
21 central retinal artery occlusion 10.3
22 vasculitis 10.3
23 systemic lupus erythematosus 10.3
24 hepatitis 10.2
25 neuroretinitis 10.2
26 retinal vasculitis 10.2
27 hereditary spherocytosis 10.2
28 hepatitis c 10.2
29 arteries, anomalies of 10.2
30 herpes zoster 10.2
31 lymphoma 10.2
32 carotid artery disease 10.2
33 spinal cord infarction 10.1 MTHFR SERPINC1
34 marantic endocarditis 10.1 MTHFR SERPINC1
35 livedoid vasculitis 10.1 MTHFR SERPINC1
36 optic neuritis 10.1
37 neovascular glaucoma 10.1
38 neuritis 10.1
39 optic nerve disease 10.1
40 retinitis 10.1
41 neuropathy 10.1
42 toxoplasmosis 10.1
43 hepatic infarction 10.1 MTHFR SERPINC1
44 thrombophlebitis 10.1 MTHFR SERPINC1
45 antithrombin iii deficiency 10.1 MTHFR SERPINC1
46 myocardial infarction 10.1
47 polyarteritis nodosa, childhood-onset 10.1
48 polyarteritis nodosa 10.1
49 herpes zoster ophthalmicus 10.1
50 intracranial thrombosis 10.1 MTHFR SERPINC1

Comorbidity relations with Branch Retinal Artery Occlusion via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Branch Retinal Artery Occlusion:



Diseases related to Branch Retinal Artery Occlusion

Symptoms & Phenotypes for Branch Retinal Artery Occlusion

UMLS symptoms related to Branch Retinal Artery Occlusion:


amaurosis fugax

Drugs & Therapeutics for Branch Retinal Artery Occlusion

Drugs for Branch Retinal Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 66)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Not Applicable 347396-82-1 459903
2 Angiogenesis Inhibitors Phase 4,Phase 2,Phase 3,Not Applicable
3 Angiogenesis Modulating Agents Phase 4,Phase 2,Phase 3,Not Applicable
4 Insulin, Globin Zinc Phase 4
5 insulin Phase 4
6 Anticoagulants Phase 4,Phase 3
7 Platelet Aggregation Inhibitors Phase 4,Phase 3
8 Fibrinolytic Agents Phase 4,Phase 3
9
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
10
Salicylic acid Approved, Investigational, Vet_approved Phase 3 69-72-7 338
11
Warfarin Approved Phase 3 81-81-2 6691 54678486
12
Phylloquinone Approved, Investigational Phase 3 84-80-0
13
Apixaban Approved Phase 3 503612-47-3 10182969
14
Phenindione Approved, Investigational Phase 3 83-12-5 4760
15
Thrombin Approved, Investigational Phase 3
16
Acenocoumarol Approved, Investigational Phase 3 152-72-7 9052 54676537
17
Rivaroxaban Approved Phase 3 366789-02-8
18
Edoxaban Approved Phase 3 480449-70-5
19
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
20
Acetazolamide Approved, Vet_approved Phase 3 59-66-5 1986
21
Menadione Approved, Nutraceutical Phase 3 58-27-5 4055
22
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
23
Dabigatran Investigational Phase 3 211914-51-1
24 Neurotransmitter Agents Phase 3,Phase 2
25 Antipyretics Phase 3
26 Anti-Inflammatory Agents, Non-Steroidal Phase 3
27 Plasminogen Phase 3
28 Cyclooxygenase Inhibitors Phase 3
29 Peripheral Nervous System Agents Phase 3
30 Anti-Inflammatory Agents Phase 3
31 Antirheumatic Agents Phase 3
32 Analgesics, Non-Narcotic Phase 3
33 Pharmaceutical Solutions Phase 3
34 Analgesics Phase 3
35 Tissue Plasminogen Activator Phase 3
36 Antithrombin III Phase 3
37 Menaquinone Phase 3
38 Factor Xa Inhibitors Phase 3
39 Serine Proteinase Inhibitors Phase 3
40 HIV Protease Inhibitors Phase 3
41
protease inhibitors Phase 3
42 naphthoquinone Phase 3
43 Vitamin K Phase 3
44 Vitamins Phase 3
45 Antithrombins Phase 3
46 Carbonic Anhydrase Inhibitors Phase 3
47 Natriuretic Agents Phase 3
48 calcium heparin Phase 3
49 Adrenergic Antagonists Phase 3
50 Adrenergic beta-Antagonists Phase 3

Interventional clinical trials:

(show all 32)
# Name Status NCT ID Phase Drugs
1 Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab Recruiting NCT02665689 Phase 4 ranibizumab
2 Study of Antithrombotic Treatment After IntraCerebral Haemorrhage Recruiting NCT03186729 Phase 4 Antithrombotic Agent
3 Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy Unknown status NCT02769169 Phase 2, Phase 3 Lucentis® (Raibizumab) double-dose;Lucentis® (Raibizumab) regular-dose
4 A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion Recruiting NCT03197194 Phase 3 Alteplase;acetylsalicylic acid;Placebo Oral Tablet;placebo IV
5 Start or STop Anticoagulants Randomised Trial (SoSTART) Recruiting NCT03153150 Phase 3 Apixaban;Rivaroxaban;Edoxaban;Dabigatran;Acenocoumarol;Phenindione;Warfarin
6 EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye Terminated NCT00637468 Phase 3 Intravenous injection of heparin;Intravenous injection of acetazolamide;Topical use of beta-blocker;Isovolaemic haemodilution;Acetylsalicylic acid
7 The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform Unknown status NCT00802698 Phase 1, Phase 2
8 The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo Unknown status NCT03090087 Phase 2 Regadenoson
9 Hyperbaric Chamber for Central Retinal Vein Occlusion (CRVO) Patients Unknown status NCT02405741 Phase 2
10 Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348633
11 Obstructive Sleep Apnea, Retinal Vein Occlusion, Retinal Artery Occlusion Unknown status NCT01291862 Not Applicable
12 Spectral-domain Optical Coherence Tomography of the Eye Unknown status NCT02614625
13 Reconstruction of Pathological Changes of the Ophthalmic Artery in Patients With Retinal Artery Occlusion Completed NCT02679716 Not Applicable
14 Ocular Discomfort Assessment After Intravitreal Injections Completed NCT02806830 Not Applicable Optive
15 Transcorneal Electrical Stimulation Therapy for Retinal Disease Completed NCT00804102 Not Applicable
16 Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma Completed NCT02097134 Not Applicable Melphalan
17 Plaque Prolapse Prevention Carotid Artery Stenting (3PCAS) Completed NCT02665585 Not Applicable
18 Intravitreal Ranibizumab in Exudative Age-related Macular Degeneration With Posterior Vitreomacular Adhesion Completed NCT01291121 Not Applicable
19 Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome Recruiting NCT01481662
20 New Non-invasive Modalities for Assessing Retinal Structure and Function Recruiting NCT03475173 Not Applicable
21 Study of Arterial Recanalization of the Central Retinal Artery Occlusions Recruiting NCT03049514
22 Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO) Recruiting NCT03313817
23 Spectral-domain Optical Coherence Tomography Findings in Retinal Vessel Occlusion Recruiting NCT03061526
24 OCT in Rare Chorioretinal Diseases Recruiting NCT02141308
25 Investigation of Biomarkers in Susac Syndrome Recruiting NCT01273792
26 Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion Active, not recruiting NCT03357146
27 Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning Active, not recruiting NCT02898480 Not Applicable
28 Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study Active, not recruiting NCT02390245 Not Applicable
29 Ocular Manifestations in Rheumatic Diseases Active, not recruiting NCT03753893
30 Hyperbaric Oxygen Therapy Registry Enrolling by invitation NCT02483650
31 Objective Assessment of Macular Function at Retinal and Cortical Levels Not yet recruiting NCT03517241
32 Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging Terminated NCT01717937

Search NIH Clinical Center for Branch Retinal Artery Occlusion

Cochrane evidence based reviews: retinal artery occlusion

Genetic Tests for Branch Retinal Artery Occlusion

Anatomical Context for Branch Retinal Artery Occlusion

MalaCards organs/tissues related to Branch Retinal Artery Occlusion:

42
Eye, Thyroid, Endothelial, Retina

Publications for Branch Retinal Artery Occlusion

Articles related to Branch Retinal Artery Occlusion:

(show top 50) (show all 267)
# Title Authors Year
1
Bartonella presenting as branch retinal artery occlusion in a child. ( 30710644 )
2019
2
Delayed Vision Recovery after Carotid Vascular Surgery for Branch Retinal Artery Occlusion. ( 30809403 )
2019
3
ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION: Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia. ( 30908470 )
2019
4
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30579615 )
2019
5
Visual field defects and changes in central retinal artery occlusion. ( 30605464 )
2019
6
Is Management of Central Retinal Artery Occlusion the Next Frontier in Cerebrovascular Diseases? ( 30612637 )
2019
7
Acute Vascular Ischemic Events in Patients with Central Retinal Artery Occlusion in the United States: A Nationwide Study 2003-2014. ( 30689989 )
2019
8
Central retinal artery occlusion - a new, provisional treatment approach. ( 30707925 )
2019
9
Stroke Risk Before and After Central Retinal Artery Occlusion in a US Cohort. ( 30711121 )
2019
10
Evaluation of the Association between the Risk of Central Retinal Artery Occlusion and the Concentration of Environmental Air Pollutants. ( 30736427 )
2019
11
Early Identification of Central Retinal Artery Occlusion Using Point-of-care Ultrasound. ( 30775656 )
2019
12
Herpes Zoster Ophthalmicus, Central Retinal Artery Occlusion, and Neovascular Glaucoma in an Immunocompetent Individual. ( 30820294 )
2019
13
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30827486 )
2019
14
A rare case having hemi-retinal artery occlusion in one eye and hemi-retinal vein occlusion in the other: Diverse manifestations of retinal vascular occlusion. ( 30672489 )
2019
15
Transient Retinal Artery Occlusion After Uncomplicated Rhinoplasty. ( 30730513 )
2019
16
Rate of strokes 1 year after retinal artery occlusion with analysis of risk groups. ( 30782009 )
2019
17
Incidence of retinal artery occlusion following intravitreal antivascular endothelial growth factor injections. ( 30810272 )
2019
18
RECURRENT BRANCH RETINAL ARTERY OCCLUSION FROM SUSAC SYNDROME: CASE REPORT AND REVIEW OF LITERATURE. ( 29870024 )
2018
19
Branch retinal artery occlusion as a clinical manifestation of hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) in pregnancy. ( 29068144 )
2018
20
Visibility of Blood Flow on Optical Coherence Tomography Angiography in a Case of Branch Retinal Artery Occlusion. ( 29403595 )
2018
21
Differentiating Occult Branch Retinal Artery Occlusion from Primary Open-angle Glaucoma. ( 29370018 )
2018
22
Branch retinal artery occlusion post-penetrating globe injury with intraocular foreign body. ( 29283146 )
2018
23
Bilateral central retinal artery occlusion from catastrophic antiphospholipid syndrome. ( 30420561 )
2018
24
Optical Coherence Tomography Angiography in Branch Retinal Artery Occlusion. ( 29988838 )
2018
25
Hereditary spherocytosis presenting with branch retinal artery occlusion. ( 30247736 )
2018
26
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects. ( 30255822 )
2018
27
Longitudinal Changes of Retinal Thicknesses in Branch Retinal Artery Occlusion: Spectral-Domain Optical Coherence Tomography Study. ( 30267095 )
2018
28
Chronic lymphocytic leukaemia presenting as branch retinal artery occlusion and optic disc infiltration. ( 30317214 )
2018
29
Hereditary spherocytosis presenting with branch retinal artery occlusion. ( 30418630 )
2018
30
Combined central retinal vein occlusion and branch retinal artery occlusion. ( 30451204 )
2018
31
Retinal Endovascular Surgery with Tissue Plasminogen Activator Injection for Central Retinal Artery Occlusion. ( 30022948 )
2018
32
Central Retinal Artery Occlusion Due to Intraorbital Ophthalmic Artery Aneurysm. ( 30052553 )
2018
33
Is Management of Central Retinal Artery Occlusion the Next Frontier in Cerebrovascular Diseases? ( 30060907 )
2018
34
Optical Coherence Tomography Measurement and Visual Outcome in Acute Central Retinal Artery Occlusion. ( 30091309 )
2018
35
Amalric triangular sign in a case of central retinal artery occlusion combined with posterior ciliary artery occlusion - Case report. ( 30094393 )
2018
36
CENTRAL RETINAL ARTERY OCCLUSION WITH CILIORETINAL ARTERY SPARING AFTER LASER-ASSISTED IN SITU KERATOMILEUSIS. ( 30106799 )
2018
37
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30153430 )
2018
38
Central retinal artery occlusion in a young child secondary to resistance to activated protein C. ( 30217606 )
2018
39
Central Retinal Artery Occlusion Following Hyaluronic Acid Fillers Injection. ( 30219170 )
2018
40
Effect of hyperbaric oxygen treatment in central retinal artery occlusion. ( 30241121 )
2018
41
Hyperbaric oxygen therapy in the treatment of central retinal artery occlusion. ( 30260139 )
2018
42
Urgent Evaluation of the Patient With Acute Central Retinal Artery Occlusion. ( 30286941 )
2018
43
Central retinal artery occlusion on postoperative day one after vitreoretinal surgery. ( 30364763 )
2018
44
Central retinal artery occlusion as an onset form of Takayasu's arteritis. ( 30424934 )
2018
45
Central retinal artery occlusion. ( 30451166 )
2018
46
Is Management of Central Retinal Artery Occlusion the Next Frontier in Cerebrovascular Diseases? ( 30529221 )
2018
47
Neurofibromatosis Type 1 Vasculopathy Presenting as Impending Central Retinal Artery Occlusion. ( 30540635 )
2018
48
Successful treatment of central retinal artery occlusion using hyperbaric oxygen therapy. ( 30571907 )
2018
49
Risk of retinal artery occlusion in patients with diabetes mellitus: A retrospective large-scale cohort study. ( 30091989 )
2018
50
Response to Makino: 'Hereditary spherocytosis presenting with branch retinal artery occlusion'. ( 30395319 )
2018

Variations for Branch Retinal Artery Occlusion

Expression for Branch Retinal Artery Occlusion

Search GEO for disease gene expression data for Branch Retinal Artery Occlusion.

Pathways for Branch Retinal Artery Occlusion

GO Terms for Branch Retinal Artery Occlusion

Biological processes related to Branch Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microtubule cytoskeleton organization GO:0000226 8.62 TBCE NEFL

Sources for Branch Retinal Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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