MCID: BRN026
MIFTS: 38

Branch Retinal Artery Occlusion

Categories: Cardiovascular diseases, Eye diseases

Aliases & Classifications for Branch Retinal Artery Occlusion

MalaCards integrated aliases for Branch Retinal Artery Occlusion:

Name: Branch Retinal Artery Occlusion 12 15 74
Retinal Artery Occlusion 45 74
Arterial Retinal Branch Occlusion 12
Retinal Arterial Branch Occlusion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13094
ICD9CM 36 362.32
MeSH 45 D015356
NCIt 51 C34436
SNOMED-CT 69 50821009
ICD10 34 H34.23

Summaries for Branch Retinal Artery Occlusion

MalaCards based summary : Branch Retinal Artery Occlusion, also known as retinal artery occlusion, is related to retinal vascular occlusion and retinal artery occlusion, and has symptoms including amaurosis fugax An important gene associated with Branch Retinal Artery Occlusion is MTHFR (Methylenetetrahydrofolate Reductase). The drugs Ranibizumab and Angiogenesis Modulating Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and brain.

Related Diseases for Branch Retinal Artery Occlusion

Diseases related to Branch Retinal Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 229)
# Related Disease Score Top Affiliating Genes
1 retinal vascular occlusion 32.2 FANCG MTHFR SERPINC1
2 retinal artery occlusion 31.9 MTHFR SERPINC1
3 retinal vein occlusion 30.9 MTHFR SERPINC1
4 central retinal vein occlusion 30.6 MTHFR SERPINC1
5 homocysteinemia 30.4 MTHFR SERPINC1
6 ischemic optic neuropathy 30.3 MTHFR SERPINC1
7 nonarteritic anterior ischemic optic neuropathy 30.3 MTHFR SERPINC1
8 stroke, ischemic 30.2 MTHFR SERPINC1
9 antiphospholipid syndrome 30.2 MTHFR SERPINC1
10 patent foramen ovale 30.2 MTHFR SERPINC1
11 thrombosis 30.1 MTHFR SERPINC1
12 protein s deficiency 30.1 MTHFR SERPINC1
13 thrombophilia 30.1 MTHFR SERPINC1
14 livedoid vasculitis 29.9 MTHFR SERPINC1
15 homocystinuria 29.8 MTHFR SERPINC1
16 thrombophilia due to activated protein c resistance 29.8 MTHFR SERPINC1
17 arteritic anterior ischemic optic neuropathy 29.8 FANCG MTHFR
18 budd-chiari syndrome 29.8 MTHFR SERPINC1
19 transient retinal arterial occlusion 12.5
20 partial arterial retinal occlusion 11.8
21 susac syndrome 11.7
22 retinal ischemia 11.7
23 lupus erythematosus 10.3
24 central retinal artery occlusion 10.3
25 vasculitis 10.3
26 systemic lupus erythematosus 10.3
27 yemenite deaf-blind hypopigmentation syndrome 10.2
28 hepatitis 10.2
29 neuroretinitis 10.2
30 retinal vasculitis 10.2
31 hereditary spherocytosis 10.2
32 hepatitis c 10.2
33 chorioretinitis 10.2
34 arteries, anomalies of 10.2
35 herpes zoster 10.2
36 cataract 10.2
37 lymphoma 10.2
38 carotid artery disease 10.2
39 spinal cord infarction 10.1 MTHFR SERPINC1
40 marantic endocarditis 10.1 MTHFR SERPINC1
41 optic neuritis 10.1
42 carotid stenosis 10.1
43 neovascular glaucoma 10.1
44 neuritis 10.1
45 optic nerve disease 10.1
46 retinitis 10.1
47 neuropathy 10.1
48 toxoplasmosis 10.1
49 hepatic infarction 10.1 MTHFR SERPINC1
50 thrombophlebitis 10.1 MTHFR SERPINC1

Comorbidity relations with Branch Retinal Artery Occlusion via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Branch Retinal Artery Occlusion:



Diseases related to Branch Retinal Artery Occlusion

Symptoms & Phenotypes for Branch Retinal Artery Occlusion

UMLS symptoms related to Branch Retinal Artery Occlusion:


amaurosis fugax

Drugs & Therapeutics for Branch Retinal Artery Occlusion

Drugs for Branch Retinal Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 66)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Not Applicable 347396-82-1 459903
2 Angiogenesis Modulating Agents Phase 4,Phase 2,Phase 3,Not Applicable
3 Angiogenesis Inhibitors Phase 4,Phase 2,Phase 3,Not Applicable
4 Insulin, Globin Zinc Phase 4
5 insulin Phase 4
6 Fibrinolytic Agents Phase 4,Phase 3
7 Platelet Aggregation Inhibitors Phase 4,Phase 3
8 Anticoagulants Phase 4,Phase 3
9
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
10
Salicylic acid Approved, Investigational, Vet_approved Phase 3 69-72-7 338
11
Edoxaban Approved Phase 3 480449-70-5
12
Phenindione Approved, Investigational Phase 3 83-12-5 4760
13 Menaquinone Approved, Investigational Phase 3 1182-68-9
14
Phylloquinone Approved, Investigational Phase 3 84-80-0
15
Warfarin Approved Phase 3 81-81-2 54678486 6691
16
Rivaroxaban Approved Phase 3 366789-02-8
17
Thrombin Approved, Investigational Phase 3
18
Apixaban Approved Phase 3 503612-47-3 10182969
19
Acenocoumarol Approved, Investigational Phase 3 152-72-7 54676537 9052
20
Heparin Approved, Investigational Phase 3 9005-49-6 46507594 772
21
Acetazolamide Approved, Vet_approved Phase 3 59-66-5 1986
22
Menadione Approved, Nutraceutical Phase 3 58-27-5 4055
23
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
24
Dabigatran Investigational Phase 3 211914-51-1
25 Neurotransmitter Agents Phase 3,Phase 2
26 Antipyretics Phase 3
27 Anti-Inflammatory Agents, Non-Steroidal Phase 3
28 Analgesics, Non-Narcotic Phase 3
29 Peripheral Nervous System Agents Phase 3
30 Pharmaceutical Solutions Phase 3
31 Anti-Inflammatory Agents Phase 3
32 Tissue Plasminogen Activator Phase 3
33 Plasminogen Phase 3
34 Cyclooxygenase Inhibitors Phase 3
35 Antirheumatic Agents Phase 3
36 Analgesics Phase 3
37 HIV Protease Inhibitors Phase 3
38 Vitamins Phase 3
39 naphthoquinone Phase 3
40 Factor Xa Inhibitors Phase 3
41
protease inhibitors Phase 3
42 Antithrombin III Phase 3
43 Vitamin K Phase 3
44 Antithrombins Phase 3
45 Serine Proteinase Inhibitors Phase 3
46 Natriuretic Agents Phase 3
47 Anticonvulsants Phase 3
48 diuretics Phase 3
49 Adrenergic beta-Antagonists Phase 3
50 calcium heparin Phase 3

Interventional clinical trials:

(show all 34)
# Name Status NCT ID Phase Drugs
1 Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab Recruiting NCT02665689 Phase 4 ranibizumab
2 Study of Antithrombotic Treatment After IntraCerebral Haemorrhage Recruiting NCT03186729 Phase 4 Antithrombotic Agent
3 Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy Unknown status NCT02769169 Phase 2, Phase 3 Lucentis® (Raibizumab) double-dose;Lucentis® (Raibizumab) regular-dose
4 A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion Recruiting NCT03197194 Phase 3 Alteplase;acetylsalicylic acid;Placebo Oral Tablet;placebo IV
5 Start or STop Anticoagulants Randomised Trial (SoSTART) Recruiting NCT03153150 Phase 3 Apixaban;Rivaroxaban;Edoxaban;Dabigatran;Acenocoumarol;Phenindione;Warfarin
6 EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye Terminated NCT00637468 Phase 3 Intravenous injection of heparin;Intravenous injection of acetazolamide;Topical use of beta-blocker;Isovolaemic haemodilution;Acetylsalicylic acid
7 The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform Unknown status NCT00802698 Phase 1, Phase 2
8 The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo Unknown status NCT03090087 Phase 2 Regadenoson
9 Hyperbaric Chamber for Central Retinal Vein Occlusion (CRVO) Patients Unknown status NCT02405741 Phase 2
10 the Treatment of Human Bone Marrow Mesenchymal Stem Cells in Ocular Corneal Burn Completed NCT02325843 Phase 2
11 Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348633
12 Obstructive Sleep Apnea, Retinal Vein Occlusion, Retinal Artery Occlusion Unknown status NCT01291862 Not Applicable
13 Spectral-domain Optical Coherence Tomography of the Eye Unknown status NCT02614625
14 Reconstruction of Pathological Changes of the Ophthalmic Artery in Patients With Retinal Artery Occlusion Completed NCT02679716 Not Applicable
15 Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning Completed NCT02898480 Not Applicable
16 Ocular Discomfort Assessment After Intravitreal Injections Completed NCT02806830 Not Applicable Optive
17 Transcorneal Electrical Stimulation Therapy for Retinal Disease Completed NCT00804102 Not Applicable
18 Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma Completed NCT02097134 Not Applicable Melphalan
19 Plaque Prolapse Prevention Carotid Artery Stenting (3PCAS) Completed NCT02665585 Not Applicable
20 Intravitreal Ranibizumab in Exudative Age-related Macular Degeneration With Posterior Vitreomacular Adhesion Completed NCT01291121 Not Applicable
21 Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome Recruiting NCT01481662
22 New Non-invasive Modalities for Assessing Retinal Structure and Function Recruiting NCT03475173 Not Applicable
23 Study of Arterial Recanalization of the Central Retinal Artery Occlusions Recruiting NCT03049514
24 Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO) Recruiting NCT03313817
25 Spectral-domain Optical Coherence Tomography Findings in Retinal Vessel Occlusion Recruiting NCT03061526
26 OCT in Rare Chorioretinal Diseases Recruiting NCT02141308
27 Atrial Cardiomyopathy in Patients With Stroke of Undetected Mechanism Recruiting NCT03830983
28 Investigation of Biomarkers in Susac Syndrome Recruiting NCT01273792
29 Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion Active, not recruiting NCT03357146
30 Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study Active, not recruiting NCT02390245 Not Applicable
31 Ocular Manifestations in Rheumatic Diseases Active, not recruiting NCT03753893
32 Hyperbaric Oxygen Therapy Registry Enrolling by invitation NCT02483650
33 Objective Assessment of Macular Function at Retinal and Cortical Levels Not yet recruiting NCT03517241
34 Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging Terminated NCT01717937

Search NIH Clinical Center for Branch Retinal Artery Occlusion

Cochrane evidence based reviews: retinal artery occlusion

Genetic Tests for Branch Retinal Artery Occlusion

Anatomical Context for Branch Retinal Artery Occlusion

MalaCards organs/tissues related to Branch Retinal Artery Occlusion:

42
Eye, Bone, Brain, Heart, Bone Marrow, Retina, Thyroid

Publications for Branch Retinal Artery Occlusion

Articles related to Branch Retinal Artery Occlusion:

(show top 50) (show all 891)
# Title Authors Year
1
Hereditary spherocytosis presenting with branch retinal artery occlusion. ( 30418630 )
2019
2
Bartonella presenting as branch retinal artery occlusion in a child. ( 30710644 )
2019
3
Delayed Vision Recovery after Carotid Vascular Surgery for Branch Retinal Artery Occlusion. ( 30809403 )
2019
4
ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION: Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia. ( 30908470 )
2019
5
Visualization of a retinal embolus associated with branch retinal artery occlusion with OCT-angiography. ( 31097314 )
2019
6
CENTRAL RETINAL ARTERY OCCLUSION WITH DOUBLE CILIORETINAL ARTERY SPARING. ( 28085758 )
2019
7
Central retinal artery occlusion showing features of paracentral acute middle maculopathy following uncomplicated pterygium surgery. ( 29962106 )
2019
8
Central Retinal Artery Occlusion Due to Intraorbital Ophthalmic Artery Aneurysm. ( 30052553 )
2019
9
Central retinal artery occlusion as an onset form of Takayasu's arteritis. ( 30424934 )
2019
10
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30579615 )
2019
11
Visual field defects and changes in central retinal artery occlusion. ( 30605464 )
2019
12
Is Management of Central Retinal Artery Occlusion the Next Frontier in Cerebrovascular Diseases? ( 30612637 )
2019
13
Acute Vascular Ischemic Events in Patients with Central Retinal Artery Occlusion in the United States: A Nationwide Study 2003-2014. ( 30689989 )
2019
14
Central retinal artery occlusion-A new, provisional treatment approach. ( 30707925 )
2019
15
Stroke Risk Before and After Central Retinal Artery Occlusion in a US Cohort. ( 30711121 )
2019
16
Evaluation of the Association between the Risk of Central Retinal Artery Occlusion and the Concentration of Environmental Air Pollutants. ( 30736427 )
2019
17
Early Identification of Central Retinal Artery Occlusion Using Point-of-care Ultrasound. ( 30775656 )
2019
18
Herpes Zoster Ophthalmicus, Central Retinal Artery Occlusion, and Neovascular Glaucoma in an Immunocompetent Individual. ( 30820294 )
2019
19
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30827486 )
2019
20
Central retinal artery occlusion after endovascular coil embolization for internal carotid artery aneurysm. ( 30918825 )
2019
21
Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. ( 30935476 )
2019
22
Preferred practice pattern for central retinal artery occlusion management. ( 30946807 )
2019
23
Intravenous Prostaglandin E1 Infusion for Acute Central Retinal Artery Occlusion. ( 31100175 )
2019
24
Response to Makino: 'Hereditary spherocytosis presenting with branch retinal artery occlusion'. ( 30395319 )
2019
25
A rare case having hemi-retinal artery occlusion in one eye and hemi-retinal vein occlusion in the other: Diverse manifestations of retinal vascular occlusion. ( 30672489 )
2019
26
Transient Retinal Artery Occlusion After Uncomplicated Rhinoplasty. ( 30730513 )
2019
27
Rate of strokes 1 year after retinal artery occlusion with analysis of risk groups. ( 30782009 )
2019
28
Incidence of retinal artery occlusion following intravitreal antivascular endothelial growth factor injections. ( 30810272 )
2019
29
Bilateral central retinal artery occlusion from catastrophic antiphospholipid syndrome. ( 30420561 )
2018
30
Branch retinal artery occlusion as a clinical manifestation of hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) in pregnancy. ( 29068144 )
2018
31
Branch retinal artery occlusion post-penetrating globe injury with intraocular foreign body. ( 29283146 )
2018
32
Differentiating Occult Branch Retinal Artery Occlusion from Primary Open-angle Glaucoma. ( 29370018 )
2018
33
Visibility of Blood Flow on Optical Coherence Tomography Angiography in a Case of Branch Retinal Artery Occlusion. ( 29403595 )
2018
34
RECURRENT BRANCH RETINAL ARTERY OCCLUSION FROM SUSAC SYNDROME: CASE REPORT AND REVIEW OF LITERATURE. ( 29870024 )
2018
35
Optical Coherence Tomography Angiography in Branch Retinal Artery Occlusion. ( 29988838 )
2018
36
Hereditary spherocytosis presenting with branch retinal artery occlusion. ( 30247736 )
2018
37
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects. ( 30255822 )
2018
38
Longitudinal Changes of Retinal Thicknesses in Branch Retinal Artery Occlusion: Spectral-Domain Optical Coherence Tomography Study. ( 30267095 )
2018
39
Chronic lymphocytic leukaemia presenting as branch retinal artery occlusion and optic disc infiltration. ( 30317214 )
2018
40
Combined central retinal vein occlusion and branch retinal artery occlusion. ( 30451204 )
2018
41
Current treatment of central retinal artery occlusion: a national survey. ( 29236169 )
2018
42
Ophthalmic artery MRI in an arteritis-related central retinal artery occlusion. ( 29358510 )
2018
43
Intra-retinal Arterial Cannulation using a Microneedle for Central Retinal Artery Occlusion. ( 29358594 )
2018
44
Thrombus in Lamina Cribrosa Seen Using Swept-Source Optical Coherence Tomography in Eye With Central Retinal Artery Occlusion. ( 29360684 )
2018
45
Intra-Arterial Thrombolytic Therapy Is Not a Therapeutic Option for Filler-Related Central Retinal Artery Occlusion. ( 29378380 )
2018
46
Central retinal artery occlusion during vitrectomy: Immediate retinal revascularization following induction of posterior vitreous detachment. ( 29468216 )
2018
47
Bilateral central retinal artery occlusion as presenting manifestation of human immunodeficiency virus infection. ( 29480272 )
2018
48
Intra-Arterial Thrombolysis for Acute Central Retinal Artery Occlusion: A Systematic Review and Meta-Analysis. ( 29527185 )
2018
49
Management of central retinal artery occlusion following successful hyperbaric oxygen therapy: case report. ( 29571239 )
2018
50
Ischemic Stroke Risk in Medicare Beneficiaries with Central Retinal Artery Occlusion: A Retrospective Cohort Study. ( 29574676 )
2018

Variations for Branch Retinal Artery Occlusion

Expression for Branch Retinal Artery Occlusion

Search GEO for disease gene expression data for Branch Retinal Artery Occlusion.

Pathways for Branch Retinal Artery Occlusion

GO Terms for Branch Retinal Artery Occlusion

Biological processes related to Branch Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microtubule cytoskeleton organization GO:0000226 8.62 NEFL TBCE

Sources for Branch Retinal Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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