Aliases & Classifications for Brawny Scleritis

MalaCards integrated aliases for Brawny Scleritis:

Name: Brawny Scleritis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14287
ICD9CM 34 379.06
SNOMED-CT 67 91612009
ICD10 32 H15.02
UMLS 71 C0155356

Summaries for Brawny Scleritis

Disease Ontology : 12 An anterior scleritis thta is characterized by painful inflammation and tender nodule formation of the anterior sclera and has symptom pain, red eyes, photophobia, tearing, blurry vision, and appearance of eye surface irregularity. Nodular scleritis can be caused by autoimmune diseases, connective tissue diseases, and infection.

MalaCards based summary : Brawny Scleritis is related to vascular disease and scleritis, and has symptoms including pain An important gene associated with Brawny Scleritis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Toxoplasmosis and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. Affiliated tissues include eye, and related phenotype is renal/urinary system.

Related Diseases for Brawny Scleritis

Diseases related to Brawny Scleritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 vascular disease 29.5 IFNG CD40LG ACE
2 scleritis 10.6
3 exophthalmos 10.3
4 ocular tuberculosis 10.0 IFNG ACE
5 fuchs' heterochromic uveitis 10.0 IFNG ACE
6 constrictive pericarditis 10.0 IFNG ACE
7 berylliosis 10.0 IFNG ACE
8 cardiac sarcoidosis 10.0 IFNG ACE
9 acute pyelonephritis 10.0 IFNG ACE
10 pyelonephritis 10.0 IFNG ACE
11 complex regional pain syndrome 10.0 IFNG ACE
12 aphthous stomatitis 10.0 IFNG ACE
13 pulmonary sarcoidosis 10.0 IFNG ACE
14 trypanosomiasis 9.9 IFNG ACE
15 chagas disease 9.9 IFNG ACE
16 histoplasmosis meningitis 9.9 CD40LG ACE
17 neuroretinitis 9.9 CD40LG ACE
18 optic papillitis 9.9 CD40LG ACE
19 granulomatous dermatitis 9.9 CD40LG ACE
20 cat-scratch disease 9.9 CD40LG ACE
21 iritis 9.9 CD40LG ACE
22 iridocyclitis 9.9 CD40LG ACE
23 cranial nerve palsy 9.9 CD40LG ACE
24 raynaud disease 9.9 CD40LG ACE
25 anuria 9.9 CD40LG ACE
26 papilledema 9.9 CD40LG ACE
27 retinal vasculitis 9.9 CD40LG ACE
28 facial nerve disease 9.9 CD40LG ACE
29 facial paralysis 9.9 CD40LG ACE
30 drug allergy 9.9 CD40LG ACE
31 hypersensitivity vasculitis 9.9 CD40LG ACE
32 pyelitis 9.9 CD40LG ACE
33 hypersensitivity reaction type iii disease 9.9 CD40LG ACE
34 acute kidney tubular necrosis 9.9 CD40LG ACE
35 aspiration pneumonia 9.9 CD40LG ACE
36 panuveitis 9.9 CD40LG ACE
37 endocardium disease 9.9 CD40LG ACE
38 pulmonary artery disease 9.9 CD40LG ACE
39 coronavirus infectious disease 9.8 CD40LG ACE
40 iga glomerulonephritis 9.8 CD40LG ACE
41 glomerulonephritis 9.8 CD40LG ACE
42 pericardial effusion 9.8 CD40LG ACE
43 intermittent claudication 9.8 CD40LG ACE
44 vein disease 9.8 CD40LG ACE
45 retinal vein occlusion 9.8 CD40LG ACE
46 acute cystitis 9.8 CD40LG ACE
47 limited scleroderma 9.8 CD40LG ACE
48 interstitial nephritis 9.8 CD40LG ACE
49 histoplasmosis 9.8 IFNG CD40LG
50 meningitis 9.8 IFNG CD40LG

Graphical network of the top 20 diseases related to Brawny Scleritis:



Diseases related to Brawny Scleritis

Symptoms & Phenotypes for Brawny Scleritis

Symptoms:

12
  • pain

MGI Mouse Phenotypes related to Brawny Scleritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.8 ACE CD40LG IFNG

Drugs & Therapeutics for Brawny Scleritis

Search Clinical Trials , NIH Clinical Center for Brawny Scleritis

Genetic Tests for Brawny Scleritis

Anatomical Context for Brawny Scleritis

MalaCards organs/tissues related to Brawny Scleritis:

40
Eye

Publications for Brawny Scleritis

Articles related to Brawny Scleritis:

# Title Authors PMID Year
1
Clinical manifestations of brawny scleritis. 61
434079 1979
2
Clinical manifestations of brawny scleritis. 61
677204 1978
3
[A case of brawny scleritis]. 61
5391891 1969
4
Massive Granuloma of the Sclera (Brawny Scleritis), with the Report of an Unusual Case: Pathologic Examination by Dr. F. H. Verhoeff. 61
16692330 1915
5
Brawny Scleritis. 61
19978180 1914

Variations for Brawny Scleritis

Expression for Brawny Scleritis

Search GEO for disease gene expression data for Brawny Scleritis.

Pathways for Brawny Scleritis

Pathways related to Brawny Scleritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.64 IFNG CD40LG
2
Show member pathways
11.2 IFNG CD40LG
3
Show member pathways
11.06 IFNG CD40LG
4 10.85 IFNG CD40LG
5 10.47 IFNG CD40LG
6 10.13 CD40LG ACE

GO Terms for Brawny Scleritis

Biological processes related to Brawny Scleritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-12 production GO:0032735 8.62 IFNG CD40LG

Sources for Brawny Scleritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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