MCID: BRS045
MIFTS: 31

Breast Adenoma

Categories: Cancer diseases

Aliases & Classifications for Breast Adenoma

MalaCards integrated aliases for Breast Adenoma:

Name: Breast Adenoma 12 15 74
Ademoma - Breast 12

Classifications:



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Disease Ontology 12 DOID:1625
NCIt 51 C40382
UMLS 74 C1328385

Summaries for Breast Adenoma

Disease Ontology : 12 A breast benign neoplasm that is has material basis in epithelial tissue in which tumor cells form glands or glandlike structures.

MalaCards based summary : Breast Adenoma, also known as ademoma - breast, is related to papilloma and pregnancy adenoma. An important gene associated with Breast Adenoma is NT5C1B (5'-Nucleotidase, Cytosolic IB), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Affiliated tissues include breast and skin, and related phenotypes are cellular and growth/size/body region

Related Diseases for Breast Adenoma

Diseases related to Breast Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
# Related Disease Score Top Affiliating Genes
1 papilloma 29.3 FGFR3 KRT14 KRT5 KRT7 KRT8 ODC1
2 pregnancy adenoma 28.6 A2M CD68 FGFR3 GNAS KRT14 KRT17
3 breast ductal adenoma 11.1
4 breast apocrine adenoma 11.1
5 basal cell carcinoma, infundibulocystic 10.4 KRT14 KRT17
6 thyroid hurthle cell adenoma 10.4 KRT14 PIK3CA
7 clear cell basal cell carcinoma 10.4 KRT17 KRT7
8 lichen planopilaris 10.4 KRT14 KRT5
9 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT14 KRT5
10 dermatosis papulosa nigra 10.3 FGFR3 PIK3CA
11 endolymphatic sac tumor 10.3 KRT7 KRT8
12 cervical intraepithelial neoplasia 10.3 KRT17 KRT8 ODC1
13 breast benign neoplasm 10.3 KRT14 KRT5 MED12
14 breast fibroadenoma 10.3 KRT14 KRT8 MED12
15 plasminogen activator inhibitor-1 deficiency 10.3 PLAT SERPINF2
16 thoracic benign neoplasm 10.3 KRT14 KRT5 MED12
17 oncocytic breast carcinoma 10.3 KRT14 KRT7
18 inverted transitional papilloma 10.3 KRT5 KRT7
19 ceruminoma 10.3 KRT5 KRT7
20 pre-malignant neoplasm 10.3 KRT14 KRT17 KRT5
21 in situ carcinoma 10.3 KRT14 KRT17 KRT5
22 benign mesothelioma 10.3 KRT5 KRT7
23 epidermolysis bullosa simplex, localized 10.3 KRT14 KRT5
24 hidrocystoma 10.3 KRT7 KRT8
25 skin benign neoplasm 10.3 KRT14 KRT5 ODC1
26 sensory organ benign neoplasm 10.3 KRT5 KRT7
27 brooke-spiegler syndrome 10.3 KRT14 KRT7 KRT8
28 adenoid squamous cell carcinoma 10.3 KRT7 KRT8
29 multiple enchondromatosis, maffucci type 10.3 GNAS NT5C1B
30 bile duct mucoepidermoid carcinoma 10.2 KRT5 KRT7
31 breast squamous cell carcinoma 10.2 KRT14 KRT5 PIK3CA
32 intracranial embolism 10.2 PLAT SERPINF2
33 middle ear adenoma 10.2 KRT5 KRT7
34 ductal carcinoma in situ 10.2 KRT14 KRT5 KRT8
35 benign breast adenomyoepithelioma 10.2 KRT14 KRT5 KRT7
36 eccrine sweat gland neoplasm 10.2 KRT17 KRT5 KRT7
37 epidermolysis bullosa simplex, generalized 10.2 KRT14 KRT5
38 dowling-degos disease 1 10.2 FGFR3 GNAS KRT5
39 platelet aggregation, spontaneous 10.2 PLAT SERPINF2
40 craniopharyngioma 10.2 KRT14 KRT7 KRT8
41 sweat gland disease 10.2 KRT14 KRT5 KRT7
42 tonsil cancer 10.2 KRT14 KRT5 KRT7
43 prostate squamous cell carcinoma 10.2 KRT5 KRT7 KRT8
44 oropharynx cancer 10.2 KRT14 KRT5 KRT7
45 idiopathic corneal edema 10.2 KRT19 KRT8
46 lymphoepithelioma-like carcinoma 10.2 KRT5 KRT7 KRT8
47 nasal cavity squamous cell carcinoma 10.2 KRT5 KRT7 KRT8
48 atypical choroid plexus papilloma 10.2 KRT5 KRT7 KRT8
49 spindle cell carcinoma 10.2 KRT14 KRT5 KRT7
50 breast secretory carcinoma 10.2 KRT5 KRT7 KRT8

Graphical network of the top 20 diseases related to Breast Adenoma:



Diseases related to Breast Adenoma

Symptoms & Phenotypes for Breast Adenoma

MGI Mouse Phenotypes related to Breast Adenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.28 FGFR3 GNAS H2AFX KRT14 KRT17 KRT19
2 growth/size/body region MP:0005378 10.13 FGFR3 GNAS H2AFX KRT14 KRT17 KRT19
3 cardiovascular system MP:0005385 10.11 GNAS H2AFX KRT19 KRT8 MED12 PAK4
4 mortality/aging MP:0010768 10.03 FGFR3 GNAS H2AFX KRT14 KRT17 KRT19
5 craniofacial MP:0005382 9.95 FGFR3 GNAS KRT14 KRT17 KRT5 MED12
6 digestive/alimentary MP:0005381 9.91 FGFR3 KRT14 KRT17 KRT19 KRT5 KRT8
7 integument MP:0010771 9.91 FGFR3 GNAS KRT14 KRT17 KRT19 KRT5
8 neoplasm MP:0002006 9.5 FGFR3 GNAS H2AFX KRT14 KRT19 MXI1
9 no phenotypic analysis MP:0003012 9.23 CD68 FGFR3 GNAS KRT17 KRT19 KRT5

Drugs & Therapeutics for Breast Adenoma

Search Clinical Trials , NIH Clinical Center for Breast Adenoma

Genetic Tests for Breast Adenoma

Anatomical Context for Breast Adenoma

MalaCards organs/tissues related to Breast Adenoma:

42
Breast, Skin

Publications for Breast Adenoma

Articles related to Breast Adenoma:

# Title Authors Year
1
Radio-sensitization by Piper longumine of human breast adenoma MDA-MB-231 cells in vitro. ( 24815473 )
2014
2
Ectopic breast adenoma of the anal margin: an atypical presentation of anorectal pain. ( 23229560 )
2013
3
Mutation of p53 in skin papilloma and tubular breast adenoma of albino mice. ( 16624193 )
2006
4
Ollier's disease associated with ovarian Sertoli-Leydig cell tumor and breast adenoma. ( 2029079 )
1991

Variations for Breast Adenoma

Expression for Breast Adenoma

Search GEO for disease gene expression data for Breast Adenoma.

Pathways for Breast Adenoma

GO Terms for Breast Adenoma

Cellular components related to Breast Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.7 A2M GNAS H2AFX KRT14 KRT17 KRT19
2 keratin filament GO:0045095 9.56 KRT14 KRT5 KRT7 KRT8
3 cell periphery GO:0071944 9.46 KRT14 KRT17 KRT19 KRT8
4 intermediate filament GO:0005882 9.1 KRT14 KRT17 KRT19 KRT5 KRT7 KRT8
5 cytosol GO:0005829 10.1 A2M GNAS KRT14 KRT17 KRT19 KRT5

Biological processes related to Breast Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.5 KRT14 KRT17 KRT5
2 keratinization GO:0031424 9.43 KRT14 KRT17 KRT19 KRT5 KRT7 KRT8
3 hemidesmosome assembly GO:0031581 9.26 KRT14 KRT5
4 cell differentiation involved in embryonic placenta development GO:0060706 9.16 KRT19 KRT8
5 cornification GO:0070268 9.1 KRT14 KRT17 KRT19 KRT5 KRT7 KRT8

Molecular functions related to Breast Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.91 A2M FGFR3 GNAS H2AFX KRT14 KRT17
2 structural constituent of cytoskeleton GO:0005200 8.92 KRT14 KRT17 KRT19 KRT5

Sources for Breast Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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