MCID: BRS017
MIFTS: 26

Breast Adenomyoepithelioma

Categories: Cancer diseases

Aliases & Classifications for Breast Adenomyoepithelioma

MalaCards integrated aliases for Breast Adenomyoepithelioma:

Name: Breast Adenomyoepithelioma 12 15 71
Breast Adenomyoepithelioma with Malignant Change 12
Malignant Adenomyoepithelioma of Breast 12
Adenomyoepithelioma of the Breast 12

Classifications:



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Disease Ontology 12 DOID:1642
NCIt 49 C5143 C6899
UMLS 71 C1334564 C1510795

Summaries for Breast Adenomyoepithelioma

Disease Ontology : 12 A breast myoepithelial neoplasm that affects the breast and is characterized by biphasic proliferation of both epithelial and myoepithelial cells.

MalaCards based summary : Breast Adenomyoepithelioma, also known as breast adenomyoepithelioma with malignant change, is related to benign breast adenomyoepithelioma and myoepithelial carcinoma. An important gene associated with Breast Adenomyoepithelioma is HSD11B2 (Hydroxysteroid 11-Beta Dehydrogenase 2), and among its related pathways/superpathways are Keratinization and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include breast, bone and thymus.

Wikipedia : 74 An adenomyoepithelioma of the breast is a rare tumour in the breast composed of glandular elements... more...

Related Diseases for Breast Adenomyoepithelioma

Diseases in the Breast Adenomyoepithelioma family:

Benign Breast Adenomyoepithelioma

Diseases related to Breast Adenomyoepithelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 benign breast adenomyoepithelioma 33.3 KRT7 KRT5 KRT14
2 myoepithelial carcinoma 30.8 KRT7 KRT14
3 intraductal papilloma 30.5 KRT5 KRT14
4 myoepithelioma 30.5 SERPINB5 KRT14
5 epithelial-myoepithelial carcinoma 30.3 KRT7 KRT14
6 cribriform carcinoma 29.9 KRT7 KRT5
7 pleomorphic adenoma 29.7 SERPINB5 KRT7 KRT14
8 spindle cell carcinoma 29.7 KRT7 KRT5 KRT14
9 papilloma 29.7 KRT7 KRT5 KRT14
10 adenoid cystic carcinoma 29.5 SERPINB5 KRT7 KRT5 KRT14
11 rare tumor 10.4
12 pregnancy adenoma 10.3 KRT5 KRT14
13 esophageal basaloid squamous cell carcinoma 10.3 KRT5 KRT14
14 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT5 KRT14
15 odontoma 10.3 KRT5 KRT14
16 lipid-rich carcinoma 10.3 KRT5 KRT14
17 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT5 KRT14
18 micronodular basal cell carcinoma 10.3 KRT5 KRT14
19 epidermolysis bullosa simplex, generalized 10.3 KRT5 KRT14
20 breast cancer 10.3
21 posttransplant acute limbic encephalitis 10.3
22 intraductal breast neoplasm 10.3 KRT5 KRT14
23 epidermolysis bullosa simplex, localized 10.3 KRT5 KRT14
24 intracystic papillary adenoma 10.3 KRT5 KRT14
25 reticulate acropigmentation of kitamura 10.2 KRT5 KRT14
26 hard palate cancer 10.2 KRT5 KRT14
27 vesiculobullous skin disease 10.2 KRT5 KRT14
28 sebaceous adenocarcinoma 10.2 KRT5 KRT14
29 epidermolysis bullosa simplex, dowling-meara type 10.2 KRT5 KRT14
30 adenoma 10.2
31 pachyonychia congenita 1 10.1 KRT5 KRT14
32 palmoplantar keratoderma, epidermolytic 10.1 KRT5 KRT14
33 luminal breast carcinoma 10.1 KRT5 KRT14
34 ductal carcinoma in situ 10.1
35 squamous cell papilloma 10.1
36 breast fibroadenoma 10.1
37 benign breast phyllodes tumor 10.1
38 adenosquamous carcinoma 10.1
39 tubular adenocarcinoma 10.1
40 microglandular adenosis 10.1
41 in situ carcinoma 10.1
42 rare breast tumor 10.1
43 dowling-degos disease 10.1 KRT5 KRT14
44 neurofibromatosis, type iv, of riccardi 10.0
45 osteogenic sarcoma 10.0
46 lobular neoplasia 10.0
47 thyroid tumor 10.0
48 breast myoepithelial carcinoma 10.0 SERPINB5 KRT5 KRT14
49 inverted transitional papilloma 10.0 KRT7 KRT5
50 malignant spiradenoma 10.0 KRT7 KRT5

Graphical network of the top 20 diseases related to Breast Adenomyoepithelioma:



Diseases related to Breast Adenomyoepithelioma

Symptoms & Phenotypes for Breast Adenomyoepithelioma

Drugs & Therapeutics for Breast Adenomyoepithelioma

Search Clinical Trials , NIH Clinical Center for Breast Adenomyoepithelioma

Genetic Tests for Breast Adenomyoepithelioma

Anatomical Context for Breast Adenomyoepithelioma

MalaCards organs/tissues related to Breast Adenomyoepithelioma:

40
Breast, Bone, Thymus, Skin, Lymph Node, Heart, Lung

Publications for Breast Adenomyoepithelioma

Articles related to Breast Adenomyoepithelioma:

(show all 15)
# Title Authors PMID Year
1
Clinical presentation, national practice patterns, and outcomes of breast adenomyoepithelioma. 61
31578797 2019
2
A Case of Metastatic Malignant Breast Adenomyoepithelioma With a Codon-61 Mutation of HRAS. 61
31301988 2019
3
Clinical characteristics and outcomes of benign, atypical, and malignant breast adenomyoepithelioma: a single institution's experience. 61
30982573 2019
4
Lessons From Managing the Breast Malignant Adenomyoepithelioma and the Discussion on Treatment Strategy. 61
29147448 2017
5
Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: A case series emphasizing histologic, radiologic, and clinical correlation. 61
27494340 2016
6
Adenomyoepithelioma of the breast with late pulmonary metastases - case report and review of the literature. 61
27487934 2016
7
Breast Adenomyoepithelioma: Ultrasonography, Elastography, Digital Mammography, Contrast-Enhanced Digital Mammography, and Pathology Findings of This Rare Type of Breast Tumor. 61
26366690 2015
8
Malignant adenomyoepithelioma of breast masquerading as soft tissue lytic lesion of right iliac bone: a rare entity. 61
25386443 2014
9
Breast adenomyoepithelioma: a case report with malignant proliferation of epithelial and myoepithelial elements. 61
24171817 2013
10
[Malignant adenomyoepithelioma of breast with lymph node metastasis: report of a case]. 61
24060079 2013
11
Fine-needle aspiration biopsy of breast adenomyoepithelioma: a potential false positive pitfall and presence of intranuclear cytoplasmic inclusions. 61
21548117 2012
12
[A case of breast adenomyoepithelioma that was diagnosed by local excision]. 61
22202318 2011
13
Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology. 61
12591699 2003
14
Cytologic features of the tubular variant of breast adenomyoepithelioma. 61
11726113 2001
15
[Breast adenomyoepithelioma. A case report and review of the literature]. 61
7782587 1995

Variations for Breast Adenomyoepithelioma

Expression for Breast Adenomyoepithelioma

Search GEO for disease gene expression data for Breast Adenomyoepithelioma.

Pathways for Breast Adenomyoepithelioma

Pathways related to Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.59 KRT7 KRT5 KRT14
2
Show member pathways
10.83 KRT7 KRT5 KRT14

GO Terms for Breast Adenomyoepithelioma

Cellular components related to Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.13 KRT7 KRT5 KRT14
2 keratin filament GO:0045095 8.8 KRT7 KRT5 KRT14

Biological processes related to Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.33 KRT7 KRT5 KRT14
2 hemidesmosome assembly GO:0031581 8.96 KRT5 KRT14
3 cornification GO:0070268 8.8 KRT7 KRT5 KRT14

Molecular functions related to Breast Adenomyoepithelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transition metal ion binding GO:0046914 8.62 S100P S100A3

Sources for Breast Adenomyoepithelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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