MCID: BRS004
MIFTS: 38

Breast Angiosarcoma

Categories: Cancer diseases, Cardiovascular diseases, Rare diseases

Aliases & Classifications for Breast Angiosarcoma

MalaCards integrated aliases for Breast Angiosarcoma:

Name: Breast Angiosarcoma 12 53 15
Angiosarcoma of the Breast 53 44 73
Hemangiosarcoma of the Breast 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4511
MeSH 44 C536368
NCIt 50 C5184
UMLS 73 C1332614

Summaries for Breast Angiosarcoma

Disease Ontology : 12 An angiosarcoma and sarcoma of breast and vascular neoplasm of breast that is located in the cells that line the blood vessels within the breast or underarm area.

MalaCards based summary : Breast Angiosarcoma, also known as angiosarcoma of the breast, is related to radiation induced angiosarcoma of the breast and angiosarcoma. An important gene associated with Breast Angiosarcoma is HBA1 (Hemoglobin Subunit Alpha 1), and among its related pathways/superpathways are Cushing syndrome and Melanocyte Development and Pigmentation. Affiliated tissues include breast, lung and skin, and related phenotypes are homeostasis/metabolism and integument

Related Diseases for Breast Angiosarcoma

Diseases related to Breast Angiosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 radiation induced angiosarcoma of the breast 12.5
2 angiosarcoma 10.8
3 waardenburg syndrome type 4 10.2 MITF SOX10
4 waardenburg syndrome, type 2e 10.2 MITF SOX10
5 histiocytoid hemangioma 10.2 F8 HBA1
6 waardenburg syndrome, type 3 10.2 MITF SOX10
7 waardenburg syndrome, type 4b 10.2 MITF SOX10
8 cochlear disease 10.2 MITF SOX10
9 albinism, ocular, with sensorineural deafness 10.2 MITF TYR
10 waardenburg syndrome, type 4a 10.2 MITF SOX10
11 pulmonary artery leiomyosarcoma 10.2 HBA1 SMUG1
12 hypomelanosis of ito 10.2 MITF TYR
13 hemangioma-thrombocytopenia syndrome 10.2
14 peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease 10.2 MITF SOX10
15 vitiligo-associated multiple autoimmune disease susceptibility 6 10.2 MITF TYR
16 heart cancer 10.2 HBA1 SMUG1
17 breast sarcoma 10.2 ANGPTL8 HBA1 SCN8A
18 indeterminate leprosy 10.2 F8 HBA1
19 gallbladder melanoma 10.2 MITF MLANA
20 lentigo maligna melanoma 10.1 MITF MLANA
21 halo nevi 10.1 MLANA TYR
22 alpha thalassemia-intellectual disability syndrome type 1 10.1 HBA1 SOX10
23 hermansky-pudlak syndrome 3 10.1 MITF TYR
24 small cell sarcoma 10.1 MLANA SOX10
25 melanoacanthoma 10.1 MLANA TYR
26 diffuse meningeal melanocytosis 10.1 MLANA TYR
27 albinism, oculocutaneous, type iv 10.1 MITF TYR
28 cutaneous ganglioneuroma 10.1 KIT MITF
29 hermansky-pudlak syndrome 1 10.1 SOX10 TYR
30 pericardial mesothelioma 10.1 HBA1 SMUG1
31 skin epithelioid hemangioma 10.1 CD34 HBA1
32 albinism, ocular, with late-onset sensorineural deafness 10.1 MITF SOX10 TYR
33 ovary sarcoma 10.1 CD34 HBA1
34 ovarian angiosarcoma 10.1 CD34 HBA1
35 intravascular fasciitis 10.1 CD34 HBA1
36 thyroid angiosarcoma 10.1 CD34 HBA1
37 tietz albinism-deafness syndrome 10.1 MITF SOX10 TYR
38 waardenburg syndrome, type 2a 10.1 MITF SOX10 TYR
39 waardenburg syndrome, type 1 10.1 MITF SOX10 TYR
40 mucosal melanoma 10.1 KIT MITF
41 dyschromatosis symmetrica hereditaria 10.1 MITF SOX10 TYR
42 amelanotic melanoma 10.1 KIT TYR
43 thyroid sarcoma 10.1 CD34 HBA1
44 hordeolum 10.1 CD34 HBA1
45 glomeruloid hemangioma 10.1 CD34 HBA1
46 hemangioma of liver 10.1 CD34 HBA1
47 vitiligo-associated multiple autoimmune disease susceptibility 1 10.1 MITF TYR
48 conventional angiosarcoma 10.1 CD34 HBA1
49 malignant anus melanoma 10.0 KIT MLANA
50 venous hemangioma 10.0 CD34 HBA1

Graphical network of the top 20 diseases related to Breast Angiosarcoma:



Diseases related to Breast Angiosarcoma

Symptoms & Phenotypes for Breast Angiosarcoma

MGI Mouse Phenotypes related to Breast Angiosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.92 ANGPTL8 CD34 F8 KIT MITF SMUG1
2 integument MP:0010771 9.73 CD34 KIT MITF MLANA SOX10 TYR
3 neoplasm MP:0002006 9.55 CD34 KIT SMUG1 SOX10 TYR
4 no phenotypic analysis MP:0003012 9.35 KIT MITF MLANA SOX10 TYR
5 pigmentation MP:0001186 9.02 KIT MITF MLANA SOX10 TYR

Drugs & Therapeutics for Breast Angiosarcoma

Search Clinical Trials , NIH Clinical Center for Breast Angiosarcoma

Cochrane evidence based reviews: angiosarcoma of the breast

Genetic Tests for Breast Angiosarcoma

Anatomical Context for Breast Angiosarcoma

MalaCards organs/tissues related to Breast Angiosarcoma:

41
Breast, Lung, Skin, Liver, Spleen, Heart, Small Intestine

The Foundational Model of Anatomy Ontology organs/tissues related to Breast Angiosarcoma:

19
The Cells

Publications for Breast Angiosarcoma

Articles related to Breast Angiosarcoma:

(show top 50) (show all 256)
# Title Authors Year
1
Impact of specialist management on survival from radiation-associated angiosarcoma of the breast. ( 29405251 )
2018
2
Primary Angiosarcoma of the Breast after Bilateral Breast Reduction. ( 29977639 )
2018
3
Radiation-induced angiosarcoma of the breast in a Li-Fraumeni patient. ( 30001797 )
2018
4
Diagnostic difficulties of primary angiosarcoma of the breast: a case report. ( 30131065 )
2018
5
Repeated resection-associated breast angiosarcoma: A case report. ( 30278541 )
2018
6
A rare case of primary breast angiosarcoma in a male: a case report. ( 30326852 )
2018
7
Soft tissue angiosarcoma of the breast in a patient with Klippel-Trenaunay-Weber syndrome. ( 30361716 )
2018
8
Radiation-induced angiosarcoma of the breast: a retrospective analysis of 15 years' experience at an oncology center. ( 30369653 )
2018
9
Primary and Secondary Breast Angiosarcoma: FDG PET/CT Series. ( 30371579 )
2018
10
Two cases of radiation-associated angiosarcoma of the breast. ( 30426313 )
2018
11
Management of Localized Breast Angiosarcoma by North American Radiation and Medical Oncologists. ( 30482726 )
2018
12
Reduced H3K27me3 expression in radiation-associated angiosarcoma of the breast. ( 28983701 )
2018
13
Primary breast angiosarcoma - a single institution experience from a tertiary cancer center in South India. ( 29286911 )
2018
14
First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry. ( 29303019 )
2018
15
Primary angiosarcoma of the breast-series of 11 consecutive cases-a single-centre experience. ( 29507495 )
2018
16
Mutational landscape of radiation-associated angiosarcoma of the breast. ( 29515789 )
2018
17
Radiogenic angiosarcoma of the breast: case report and systematic review of the literature. ( 29690864 )
2018
18
Radiation-Associated Angiosarcoma of the Breast: A Case Report and Literature Review. ( 29805371 )
2018
19
Clinicopathological features of breast angiosarcoma: A 16-years single-institution experience. ( 28704748 )
2017
20
Primary breast angiosarcoma in young women from the same geographic region in a short period of time: Only a coincidence or an increased risk? ( 28597488 )
2017
21
Cutaneous Radiation-associated Breast Angiosarcoma: Radicality of Surgery Impacts Survival. ( 28267696 )
2017
22
Radical chest wall resection and hyperfractionated accelerated radiotherapy for radiation-associated angiosarcoma of the breast: A safe and effective treatment strategy. ( 28845531 )
2017
23
Prognosis and treatment of non-metastatic primary and secondary breast angiosarcoma: a comparative study. ( 28449661 )
2017
24
Radiation induced angiosarcoma of the breast: outcomes from a retrospective case series. ( 28794852 )
2017
25
Breast angiosarcoma without radiation history, putatively associated with subclinical lymphedema: A case report and review of the Japanese literature. ( 28543441 )
2017
26
Primary Synchronous Bilateral Angiosarcoma of the Breast. ( 29336740 )
2017
27
Metastatic Primary Angiosarcoma of the Breast: Can We Tame It the Metronomic Way. ( 28900339 )
2017
28
Primary breast angiosarcoma: a rare presentation of rare tumor - case report. ( 28855848 )
2017
29
Primary Synchronous Bilateral Angiosarcoma of the Breast. ( 30454411 )
2017
30
Clinical outcomes in breast angiosarcoma patients: A rare tumor with unique challenges. ( 29205355 )
2017
31
Atypical Presentation of Radiation-Associated Breast Angiosarcoma: A Case Report and Review of Literature. ( 29249796 )
2017
32
Primary Angiosarcoma of the Breast: A Case Report and Review of the Literature. ( 28234720 )
2017
33
Angiosarcoma of the Breast: A Rare and Dismal Complication of Breast Surgery Associated with Radiation. ( 28316292 )
2017
34
Angiosarcoma of the Breast: A Rare and Dismal Complication of Breast Surgery Associated with Radiation. ( 30401149 )
2017
35
Angiosarcoma of the Breast: A Rare and Dismal Complication of Breast Surgery Associated with Radiation. ( 30454139 )
2017
36
Late recurrent cutaneous breast angiosarcoma in an elderly woman: A case report. ( 27123098 )
2016
37
P2.15: Treatment Outcome of Metastatic Breast Angiosarcoma to the Lung, inA aA Reference Hospital in Latin America: AA Case Report: Track: Pathology. ( 27676551 )
2016
38
Awareness of primary spontaneous hemorrhagic angiosarcoma of the breast associated with Kasabach-Merritt syndrome in a pregnant woman by enhanced magnetic resonance imaging: A CARE-compliant case report. ( 27858895 )
2016
39
Radiation-Induced Breast Angiosarcoma: Case Report and Clinical Approach. ( 26848144 )
2016
40
Primary Breast Angiosarcoma: A Retrospective Study of 36 Cases from a Single Chinese Medical Institute with Clinicopathologic and Radiologic Correlations. ( 27933680 )
2016
41
Multidisciplinary approach to breast angiosarcoma in an elderly patient: Repeated local relapses and significant objective responses. ( 26872968 )
2016
42
Radiation-induced breast angiosarcoma: a case report. ( 28101140 )
2016
43
Exsanguinating Hemorrhage during Open Biopsy in a Primary Breast Angiosarcoma: A Case Report. ( 26989288 )
2016
44
Breast Angiosarcoma with Exophytic Growth. ( 27845552 )
2016
45
Radiation-Associated Angiosarcoma of the Breast: Clinical and Pathologic Features. ( 27128306 )
2016
46
Primary breast angiosarcoma in a young woman. ( 27232295 )
2016
47
Primary angiosarcoma of the breast. ( 26867719 )
2016
48
Recurrent Primary Angiosarcoma of the Breast Presenting as Kasabach-Merritt Syndrome: A Case Report and Review of Literature. ( 27042570 )
2016
49
Radiation-Associated Angiosarcoma of the Breast: What the Radiologist Needs to Know. ( 27099969 )
2016
50
Angiosarcoma of the breast masquerading as hemangioma: exploring clinical and pathological diagnostic challenges. ( 25798409 )
2015

Variations for Breast Angiosarcoma

Expression for Breast Angiosarcoma

Search GEO for disease gene expression data for Breast Angiosarcoma.

Pathways for Breast Angiosarcoma

Pathways related to Breast Angiosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.54 KIT MITF TYR
2 10.41 KIT MITF SOX10

GO Terms for Breast Angiosarcoma

Biological processes related to Breast Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.46 CD34 KIT MITF SOX10
2 cell maturation GO:0048469 9.37 ANGPTL8 SOX10
3 stem cell differentiation GO:0048863 9.32 KIT SOX10
4 peripheral nervous system development GO:0007422 9.26 SCN8A SOX10
5 pigmentation GO:0043473 9.13 KIT MITF TYR
6 melanocyte differentiation GO:0030318 8.8 KIT MITF SOX10

Sources for Breast Angiosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....