Breast Apocrine Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Breast Apocrine Carcinoma

MalaCards integrated aliases for Breast Apocrine Carcinoma:

Name: Breast Apocrine Carcinoma ¹² ¹⁵

Apocrine Carcinoma of Breast ¹²

Apocrine Breast Carcinoma ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:6581

NCIt ⁵⁰ C5141

UMLS ⁷³ C1332316

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Summaries for Breast Apocrine Carcinoma

Disease Ontology : ¹² A breast adenocarcinoma that is characterized by abundant eosinophilic cytoplasm, large round nuclei and sharp cell borders.

MalaCards based summary : Breast Apocrine Carcinoma, also known as apocrine carcinoma of breast, is related to apocrine adenocarcinoma and breast apocrine carcinoma in situ. An important gene associated with Breast Apocrine Carcinoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Gastric cancer and Signaling by ERBB4. Affiliated tissues include bone, ovary and cervix.

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Related Diseases for Breast Apocrine Carcinoma

Diseases in the Breast Apocrine Carcinoma family:

Breast Apocrine Carcinoma in Situ

Diseases related to Breast Apocrine Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)

#	Related Disease	Score	Top Affiliating Genes
1	apocrine adenocarcinoma	30.3	ERBB2 PGR
2	breast apocrine carcinoma in situ	12.3
3	scirrhous adenocarcinoma	10.0	ERBB2 PGR
4	glassy cell carcinoma of the cervix	10.0	ERBB2 PGR
5	intracystic papillary adenoma	10.0	ERBB2 PGR
6	breast metaplastic carcinoma	10.0	ERBB2 PGR
7	progesterone-receptor negative breast cancer	10.0	ERBB2 PGR
8	breast medullary carcinoma	10.0	ERBB2 PGR
9	breast scirrhous carcinoma	10.0	ERBB2 PGR
10	progesterone-receptor positive breast cancer	10.0	ERBB2 PGR
11	breast adenoid cystic carcinoma	10.0	ERBB2 PGR
12	adenoid cystic carcinoma	10.0	ERBB2 PGR
13	uterine body mixed cancer	10.0	ERBB2 PGR
14	microglandular adenosis	10.0	ERBB2 PGR
15	inflammatory breast carcinoma	10.0	ERBB2 PGR
16	luminal breast carcinoma	10.0	ERBB2 PGR
17	breast benign neoplasm	10.0	ERBB2 PGR
18	thoracic benign neoplasm	9.9	ERBB2 PGR
19	uterine corpus cancer	9.9	ERBB2 PGR
20	breast secretory carcinoma	9.9	ERBB2 PGR
21	lipid-rich carcinoma	9.9	ERBB2 PGR
22	mixed cell type cancer	9.9	ERBB2 PGR
23	mammary paget's disease	9.9	ERBB2 PGR
24	bilateral breast cancer	9.9	ERBB2 PGR
25	primary peritoneal carcinoma	9.9	ERBB2 PGR
26	tubular adenocarcinoma	9.9	ERBB2 PGR
27	pre-malignant neoplasm	9.9	ERBB2 PGR
28	fallopian tube carcinoma	9.9	ERBB2 PGR
29	papillary adenocarcinoma	9.9	ERBB2 PGR
30	in situ carcinoma	9.9	ERBB2 PGR
31	estrogen-receptor negative breast cancer	9.9	ERBB2 PGR
32	breast fibroadenoma	9.9	ERBB2 PGR
33	breast carcinoma in situ	9.9	ERBB2 PGR
34	malignant ovarian surface epithelial-stromal neoplasm	9.9	ERBB2 PGR
35	ovary epithelial cancer	9.9	ERBB2 PGR
36	female breast cancer	9.9	ERBB2 PGR
37	serous cystadenocarcinoma	9.9	ERBB2 PGR
38	cystadenocarcinoma	9.9	ERBB2 PGR
39	cervical adenocarcinoma	9.9	ERBB2 PGR
40	estrogen-receptor positive breast cancer	9.9	ERBB2 PGR
41	sweat gland cancer	9.9	ERBB2 PGR
42	uterine anomalies	9.9	ERBB2 PGR
43	sporadic breast cancer	9.9	ERBB2 PGR
44	ductal carcinoma in situ	9.9	ERBB2 PGR
45	carcinosarcoma	9.9	ERBB2 PGR
46	ovarian serous cystadenocarcinoma	9.9	ERBB2 PGR
47	female reproductive system disease	9.9	ERBB2 PGR
48	reproductive system disease	9.9	ERBB2 PGR
49	papillary carcinoma	9.9	ERBB2 PGR
50	endometrial adenocarcinoma	9.9	ERBB2 PGR

Graphical network of the top 20 diseases related to Breast Apocrine Carcinoma:

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Symptoms & Phenotypes for Breast Apocrine Carcinoma

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Drugs & Therapeutics for Breast Apocrine Carcinoma

Search Clinical Trials , NIH Clinical Center for Breast Apocrine Carcinoma

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Genetic Tests for Breast Apocrine Carcinoma

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Anatomical Context for Breast Apocrine Carcinoma

MalaCards organs/tissues related to Breast Apocrine Carcinoma:

⁴¹

Bone, Ovary, Cervix

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Publications for Breast Apocrine Carcinoma

Articles related to Breast Apocrine Carcinoma:

#	Title	Authors	Year
1	Incidental detection of breast apocrine carcinoma via endometrial cytology. ( 22041622 )	Shiota M....Hoshiai H.	2011

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Genes for Breast Apocrine Carcinoma

Genes related to Breast Apocrine Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	PGR	Progesterone Receptor	Protein Coding	14.22	DISEASES inferred ¹⁵
2	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	13.67	DISEASES inferred ¹⁵

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Variations for Breast Apocrine Carcinoma

Cosmic variations for Breast Apocrine Carcinoma:

⁹

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM17564	PTEN	breast,NS,carcinoma,apocrine	c.766G>A	p.E256K	10:87957984-87957984	13
2	COSM23568	PTEN	breast,NS,carcinoma,apocrine	c.919G>A	p.E307K	10:87961011-87961011	13

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Expression for Breast Apocrine Carcinoma

Search GEO for disease gene expression data for Breast Apocrine Carcinoma.

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Pathways for Breast Apocrine Carcinoma

Pathways related to Breast Apocrine Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	11.62	ERBB2 PGR
2	Signaling by ERBB4 ⁶⁶ Show member pathways Downregulation of ERBB4 signaling ⁶⁶ ErbB4 signaling events ¹ Nuclear signaling by ERBB4 ⁶⁶	10.66	ERBB2 PGR

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GO Terms for Breast Apocrine Carcinoma

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